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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Indiana Center for Recovery

Situated in Bloomington, IN, Indiana Center for Recovery specializes in an array of thorough addiction treatment services tailored for both adults and young adults. The center offers detox services, programs for substance use, transitional housing, and options for sober living. Treatment modalities encompass intensive outpatient care, long-term residential support, and outpatient services. Emphasizing 12-step guidance, anger management techniques, and brief intervention strategies, the facility is equipped to serve active duty military members, as well as adult men and women. The center welcomes both male and female clients, fostering a nurturing and inclusive atmosphere for those on their recovery journey.

Indiana University West Hospital

Indiana University West Hospital, situated in Avon, IN, delivers thorough addiction treatment for adults and young adults. The facility offers intensive outpatient care, standard outpatient programs, and outpatient detox, all customized to meet specific needs. Employing strategies like brief intervention, cognitive behavioral therapy, and the Matrix Model, this center ensures excellent treatment for all clients, regardless of gender. Key advantages include custom-designed treatment plans and distinct programs addressing individual circumstances. For effective detox and substance abuse treatment in a nurturing setting, this center is committed to fostering long-term recovery.

Infinity Center of Frankfort LLC

Situated in Frankfort, KY, Infinity Center of Frankfort LLC provides targeted treatment options for adults and young adults battling substance use issues. This center offers outpatient services, including methadone/buprenorphine and naltrexone therapies, alongside traditional outpatient programs and telehealth consultations. Emphasizing cognitive behavioral therapy and specialized counseling for substance use disorders, the facility customizes its approach to meet the unique needs of each individual. Catering to both men and women, Infinity Center of Frankfort LLC is committed to a holistic and personalized methodology in the recovery process. For individuals in search of effective care and tailored treatment strategies, this center represents a promising step on the path to recovery.

Inner Voyage Recovery Center

Inner Voyage Recovery Center, situated in Woodstock, GA, delivers targeted substance abuse interventions for adults and young adults. They provide intensive outpatient, standard outpatient, and partial hospitalization programming. Their therapeutic framework incorporates 12-step facilitation, anger management, and cognitive behavioral therapy, ensuring personalized treatment plans. A distinctive feature of Inner Voyage Recovery Center is its gender-specific programs, accommodating both male and female clients. Patients receive excellent care and individualized assistance throughout their recovery process.

Innovate Recovery

Innovate Recovery, situated in Tarzana, CA, specializes in a wide array of treatment options for those aiming to address substance use challenges. This center features inpatient detox services and treatment programs tailored specifically for active military personnel, as well as adult men and women. It employs various methodologies, including 12-step strategies, anger management sessions, and brief interventions to meet the unique requirements of each individual. Prioritizing high-quality care, Innovate Recovery serves adults and young adults of all genders, offering transitional housing solutions like halfway houses and sober living arrangements. Opt for Innovate Recovery to experience evidence-based therapy within a compassionate and supportive setting.

Inland Valley Drug and Alcohol

Inland Valley Drug and Alcohol, situated in Upland, CA, stands as a premier institution dedicated to comprehensive addiction recovery. We offer complete detoxification and substance use treatment services, including hospital-level inpatient detoxification and round-the-clock care. Our programs are designed for adults, encompassing active duty military members, and address specific needs such as 12-step facilitation, anger management, and brief intervention strategies. Serving both male and female adults and young adults, Inland Valley Drug and Alcohol is dedicated to delivering exceptional addiction care within a welcoming and encouraging setting.

Infinity Health

Infinity Health, situated in Leon, IA, stands as a leading rehabilitation facility dedicated to delivering extensive care. They focus on addressing addiction and dual diagnoses, offering robust intensive outpatient services, general outpatient support, and medication-assisted treatments including methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like anger management, brief intervention, and cognitive behavioral therapy, Infinity Health is committed to successful outcomes. Their tailored programs extend to younger individuals and those facing concurrent mental health challenges, serving adults, children, and adolescents irrespective of gender. Choose Infinity Health for superior treatment aimed at sustained recovery and comprehensive well-being.

Independence Place

Independence Place, situated in Hines, OR, is a rehabilitation center providing specialized programs. It offers both extended and short-stay residential care for adults and young adults grappling with substance use disorders and associated mental health issues. Employing methods like 12-step facilitation, anger management, and brief intervention, the center serves adult men and women, including those with dual diagnoses. Independence Place distinguishes itself with gender-specific treatment tracks, ensuring personalized support for all participants. The center is recognized for its all-encompassing treatment strategies and dedication to offering excellent, customized recovery services for addiction and mental health concerns.

Indian Family Health Clinic

Situated in Great Falls, MT, the Indian Family Health Clinic provides outpatient services for substance use issues along with specialized support for individuals struggling with both substance use and significant mental health challenges in adults, as well as serious emotional difficulties in children. The center employs Regular Outpatient Treatment that incorporates evidence-based methodologies, including 12-step facilitation, anger management techniques, and short-term interventions. Special programs are designed for active military members, teenagers, and adult males, ensuring comprehensive care for adults and seniors across all genders. Individuals can anticipate top-notch, personalized support within a nurturing setting dedicated to holistic healing and recovery.

Infinity Center LLC

Infinity Center LLC, situated in Ashland, KY, provides extensive care for addiction issues affecting adults and young adults. Their expertise covers detox, addiction therapy, and managing co-occurring mental health conditions. The center offers intensive outpatient and standard outpatient services, including outpatient detox. Employing methods like 12-step support, anger resolution, and brief counseling, they serve active military, adult men, and women. Infinity Center LLC is dedicated to delivering high-quality, personalized treatment plans to guide individuals toward lasting recovery.

Infinity Health
Corydon, IA

Infinity Health in Corydon, IA, provides extensive outpatient care for individuals of all ages facing challenges with substance use, co-occurring mental health conditions, and emotional difficulties. Our specialized programs cater to adolescents and those with dual diagnoses, employing proven methods such as anger management, cognitive behavioral therapy, and the Matrix Model to deliver personalized treatment. We are distinguished by our outpatient offerings of methadone/buprenorphine and naltrexone, contributing to a comprehensive recovery strategy. Infinity Health ensures that both male and female clients receive dedicated, gender-specific support within a nurturing setting that fosters enduring well-being.

Independence House

Independence House, located in Denver, CO, provides extensive treatment options for adults and young adults dealing with substance use issues along with concurrent mental health conditions. The facility features various programs, such as intensive outpatient, outpatient, and standard outpatient treatments, employing proven methods like cognitive behavioral therapy and strategies for managing anger. Customized programs designed specifically for adult men, adult women, and trauma survivors allow for individualized attention. With a strong commitment to delivering high-quality care, Independence House is a reliable option for individuals in need of effective and empathetic rehabilitation support in the Denver region.

Indiana University Health Bloomington

Indiana University Health Bloomington in Bloomington, IN, is dedicated to assisting adults and adolescents in their recovery from substance use disorders and concurrent mental health challenges. They offer a spectrum of care including intensive outpatient services, outpatient detox, and standard outpatient programs. Their therapeutic model is grounded in proven methods like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Tailored support is available for individuals with trauma histories and those managing co-occurring conditions. Emphasizing personalized treatment plans, Indiana University Health Bloomington provides specialized care for both men and women, aiming to foster enduring sobriety and overall well-being.

Indio Substance Abuse

Situated in Indio, CA, Indio Substance Abuse delivers a wide range of treatment options for both adults and teens dealing with substance use issues. The center specializes in intensive outpatient programs, general outpatient services, and outpatient treatments utilizing medications such as methadone, buprenorphine, or naltrexone. Emphasizing techniques like 12-step participation, brief intervention, and cognitive behavioral therapy, this facility customizes its methods to meet each client's specific requirements. Unique programs are available for adolescents, as well as for adult men and women. Indio Substance Abuse is committed to providing high-quality care to all clients, establishing itself as a crucial option for effective and individualized addiction recovery in the Indio community.

Infinity Health
Osceola, IA

Situated in Osceola, IA, Infinity Health specializes in outpatient treatment for adults facing substance use disorders alongside mental health challenges. The center focuses on therapies such as anger management and cognitive behavioral therapy, offering customized care for both men and women. With specialized programs for teenagers and individuals with dual diagnoses, Infinity Health guarantees thorough support for clients of all ages. Their outpatient services include methadone, buprenorphine, and naltrexone treatments, facilitating effective and approachable recovery solutions. Select Infinity Health for high-quality, evidence-based care in a supportive setting.

Infinity Health
Knoxville, IA

Infinity Health, located in Knoxville, IA, delivers targeted substance abuse treatment for adults facing significant mental health challenges along with services for children experiencing emotional difficulties. The center features both intensive outpatient and outpatient programs, offering treatments such as methadone, buprenorphine, and naltrexone. Emphasizing approaches like cognitive behavioral therapy, anger management, and short-term interventions, Infinity Health serves both adult and youth populations. Its specialized programs for those with co-occurring conditions provide holistic support. Moreover, the facility welcomes clients of all genders, fostering an encouraging and inclusive space for individuals on their recovery journey.

Infinity Health
Chariton, IA

Infinity Health, situated in Chariton, IA, provides thorough addiction treatment and expert support for those facing co-occurring mental health challenges. Their offerings encompass intensive outpatient care, standard outpatient services, and medication-assisted treatment (methadone/buprenorphine or naltrexone). Employing proven therapeutic methods like anger management, cognitive-behavioral therapy, and the Matrix Model, Infinity Health fosters sustained recovery. The center serves adults, teenagers, and younger individuals, recognizing and responding to the distinct requirements of different genders. Infinity Health distinguishes itself through its personalized treatment strategies and dedicated assistance for individuals with intricate health concerns.

Infinity Health

Infinity Health, situated in Albia, IA, delivers extensive outpatient care for individuals of all ages struggling with substance use disorders and co-occurring mental health conditions. The center features distinct programs for younger clients and those with dual diagnoses, ensuring gender-specific and individualized support. Employing scientifically proven methods such as cognitive behavioral therapy and the Matrix Model, Infinity Health prioritizes successful outcomes through interventions like anger management and outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. They are dedicated to providing high-quality, supportive services to aid in recovery from addiction and mental health difficulties.

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Indiana Community Addiction Network in Noblesville, IN provides extensive support for overcoming addiction. They offer critical detox services, general substance use therapy, and targeted programs for those facing both addiction and significant mental health challenges. Their flexible treatment options include intensive outpatient and partial hospitalization programs, serving adults and young adults across all genders. Employing proven methods such as 12-step support, anger management techniques, and personalized care plans, the center is committed to delivering excellent, tailored treatment. For those looking for successful recovery within a nurturing setting, this facility is devoted to guiding you toward sustained well-being.

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At the Indiana Community Addiction Network in Lafayette, IN, a complete spectrum of addiction recovery solutions is available. This establishment delivers detox services, addresses substance abuse, and offers dedicated support for those managing both addiction and significant mental health challenges concurrently. Through structured programs like intensive outpatient and full-day outpatient treatment, the center serves adults and young adults across all genders. The Indiana Community Addiction Network's approach emphasizes 12-step principles, emotional regulation techniques, concise therapeutic strategies, and personalized recovery paths. Patients will receive superior, customized care designed to foster their progress toward sobriety.

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Centerville, IA

Situated in Centerville, IA, Infinity Health stands out as a premier rehabilitation center dedicated to treating substance use issues and co-occurring mental health challenges in both adults and youth. The facility offers a range of services, including intensive outpatient programs, outpatient therapy, and treatment options using methadone, buprenorphine, or naltrexone. Emphasizing anger management, cognitive behavioral therapy, and the Matrix Model, Infinity Health customizes its treatments to address the unique needs of each individual. The center also features specialized programs for adolescents and those with dual diagnoses, ensuring a holistic approach to recovery. With a commitment to providing effective and evidence-based care, Infinity Health caters to both male and female clients on their journey towards sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)