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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Innovative Health Systems Inc

Innovative Health Systems Inc, located in White Plains, NY, delivers thorough care for individuals struggling with addiction, addressing both dual diagnoses in adults and significant emotional challenges in children. Their services include intensive outpatient, standard outpatient, and day treatment programs, incorporating techniques like anger management, brief intervention strategies, and cognitive behavioral therapy. The facility features distinct programs designed for teenagers, adult men, and adult women, accommodating various age ranges and genders. Clients receive personalized, top-tier treatment aimed at promoting recovery and well-being within a nurturing setting.

Insight BH and Addiction Solutions

Insight BH and Addiction Solutions, located in New Port Richey, FL, provides a wide array of evidence-backed treatment options for adults and young adults facing substance use disorders along with co-occurring mental health issues. The center features hospital inpatient detox services, round-the-clock hospital inpatient support, and extended residential care. It offers specialized programming for active duty military personnel, as well as separate services for men and women, addressing a variety of needs. Employing methods like 12-step support, anger management, and brief intervention strategies, the center focuses on personalized treatment. Committed to high standards and customized care plans, Insight BH and Addiction Solutions is devoted to assisting individuals on their path to recovery.

Insight Into Action Therapy

Insight Into Action Therapy located in Ashburn, VA, specializes in outpatient detox services, treatment for substance use disorders, and targeted support for adults with co-occurring mental health conditions or children experiencing significant emotional challenges. This center offers outpatient options for methadone, buprenorphine, and naltrexone, and employs various methodologies including 12-step programs, anger management techniques, and brief interventions. With customized programs designed for adolescents, adult males, and females, the center addresses the needs of both adults and older individuals. Patients can anticipate high-quality, individualized care, positioning Insight Into Action Therapy as a guiding light for those in pursuit of effective recovery solutions.

Insight Recovery Center

Situated in Arden, NC, Insight Recovery Center delivers extensive addiction treatment options for both adults and young adults. The center features inpatient detox services and treatment programs, tailored specifically for adult men, adult women, and individuals who have faced intimate partner or domestic violence. Insight Recovery Center employs a range of methodologies, including 12-step facilitation, anger management, and brief intervention, to address the unique needs of each client. Additionally, the facility provides transitional housing such as halfway houses and sober living environments, fostering a nurturing atmosphere for healing. With an emphasis on high-quality care and gender-focused programs, Insight Recovery Center serves as an essential support system for those on the path to lasting recovery.

Insight Recovery Centers

Situated in Ashburn, VA, Insight Recovery Centers delivers targeted treatment for adults battling substance use disorders, including those facing significant mental health challenges concurrently. Emphasizing intensive outpatient services, as well as outpatient care and medication-assisted treatments like methadone, buprenorphine, or naltrexone, the center utilizes various therapeutic methods such as 12-step support, anger management, and focused interventions. Customized programs are designed for adult men and women, along with individuals who have undergone trauma. Catering to both adult and young adult clients of all genders, Insight Recovery Centers ensures personalized care aimed at fostering enduring recovery and comprehensive wellness.

Inspire Malibu
Agoura Hills, CA

Situated in Agoura Hills, California, Inspire Malibu is a premier rehabilitation facility that offers an extensive array of services. Focusing on detoxification, treatment for substance abuse, and addressing co-occurring mental health disorders, this center delivers long-term residential programs, residential detox services, and 24/7 support. Inspire Malibu is designed to meet the diverse needs of its clients, including programs specifically for active duty military personnel, as well as adult men and women. By employing effective methods such as 12-step principles, anger management techniques, and brief interventions, the center provides exceptional care for both adult and young adult populations. Inspire Malibu distinguishes itself through its dedication to individualized treatment plans and holistic healing approaches.

Inspire Malibu
Agoura Hills, CA

Inspire Malibu in Agoura Hills, CA, delivers a complete suite of addiction recovery services for adults and adolescents. The center features detox, comprehensive substance abuse treatment, and targeted support for those with dual diagnoses involving mental health or emotional challenges alongside addiction. Available program structures like intensive outpatient, outpatient, and day treatment allow for customized care pathways. Inspire Malibu employs a variety of evidence-based modalities including 12-step program integration, anger management techniques, and brief intervention strategies. They also offer distinct programs for active military, adult men, and adult women. Through its dedication to high-quality support and personalized recovery plans, Inspire Malibu aims to help individuals achieve enduring sobriety.

Inspire Recovery LLC
West Palm Beach, FL

Inspire Recovery LLC, situated in West Palm Beach, FL, delivers comprehensive recovery solutions. This facility specializes in intensive outpatient care, day treatment, and partial hospitalization for adults and young adults confronting addiction and associated mental health challenges. Their therapeutic modalities encompass 12-step support, anger management techniques, and brief intervention strategies. Inspire Recovery LLC extends its services to active military, teenagers, and adult men, prioritizing personalized, high-quality support. The availability of transitional housing further aids both male and female individuals in their path toward lasting sobriety.

Institute for Human Resources

The Institute for Human Resources, situated in Pontiac, IL, delivers thorough recovery programs for individuals of all ages dealing with addiction and co-occurring mental health challenges. This center offers robust outpatient treatment, general outpatient services, and specific medication-assisted treatment plans using methadone, buprenorphine, or naltrexone. Their approach emphasizes 12-step integration, techniques for managing anger, and concise intervention strategies, serving adolescents and adults across all age groups. The Institute for Human Resources is recognized for its customized support and excellent therapeutic services, establishing it as a leading provider for effective, individualized addiction recovery.

Inspire Health
Irvine, CA

Inspire Health, situated in Irvine, CA, is a leading residential facility providing extended care for individuals navigating detoxification, substance dependency, and co-occurring mental health conditions. The center features distinct treatment paths for active military members, adult males, and adult females. Through a curriculum incorporating 12-step facilitation, anger management techniques, and brief intervention strategies, Inspire Health serves adult and young adult populations of all genders. Their all-encompassing treatment and on-site detoxification services guarantee continuous support for those pursuing sobriety. Inspire Health is recognized for its high standards of care and individualized addiction recovery plans.

Inspiration Health Services LLC

Inspiration Health Services LLC, located in Fruitland, MD, delivers extensive outpatient care for individuals dealing with substance use issues and associated mental health challenges in both adults and youth. This center features personalized counseling specifically designed for those struggling with substance use disorders. It has distinct programs available for active military members, teenagers, and adult males, providing focused support for each group. With an emphasis on outpatient treatment options such as methadone/buprenorphine or naltrexone, as well as standard outpatient services, this center accommodates clients of all genders and ages. Discover exceptional care and customized assistance at Inspiration Health Services LLC.

Inspire Counseling and Support Center

Situated in Wichita, Kansas, Inspire Counseling and Support Center provides a variety of targeted rehabilitation programs for both adults and youth dealing with substance abuse and simultaneous mental health concerns. The facility features intensive outpatient programs, daytime outpatient treatment, and partial hospitalization options, employing proven methods such as cognitive behavioral therapy and anger management techniques. Emphasizing care for individuals who have gone through trauma, sexual abuse, intimate partner violence, and domestic violence, this center delivers personalized assistance for males and females in need of holistic support within a nurturing atmosphere.

Inspire Counseling and Support Center

Inspire Counseling and Support Center in Saint Cloud, FL, is dedicated to providing comprehensive and individualized addiction recovery services. They offer intensive outpatient and day treatment programs designed to address substance use disorders and co-occurring mental health conditions across all age groups, from children to adults and seniors. By integrating evidence-based therapies such as 12-step facilitation and anger management, alongside specialized programs for active duty military, adolescents, and adult men, the center ensures a personalized and effective journey toward healing and sustained well-being for every client.

Insight Human Services Inc

Insight Human Services Inc, located in Winston Salem, NC, delivers a wide array of substance abuse recovery programs. They offer intensive outpatient, day treatment, and partial hospitalization options for adults and young people. Utilizing approaches like 12-step facilitation, anger management, and cognitive behavioral therapy, this center is equipped to assist individuals facing dual diagnoses of mental health and addiction challenges. Tailored services are provided for adolescents, adult women, and those with significant emotional disturbances. Insight Human Services Inc is committed to providing excellent, gender-tailored support to all clients in a caring and understanding setting.

Inspiration House
Fort Wayne, IN

Situated in Fort Wayne, IN, Inspiration House delivers a wide variety of services for substance use treatment. The center features both outpatient and residential programs designed for adults and young adults of any gender. Emphasizing 12-step support, anger management, and brief intervention strategies, Inspiration House is recognized for its customized treatment plans. The facility also provides transitional housing and sober living opportunities for individuals requiring assistance. Committed to offering excellent care, this center serves as a guiding light for those on their journey to recovery.

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Situated in Fairfax, VA, the Inova CATS Program specializes in rehabilitation for adults and young adults facing challenges with substance use and concurrent mental health issues. The center offers a range of services, including intensive outpatient care, outpatient day programs, and partial hospitalization, all customized to meet the unique needs of each client. Emphasizing therapeutic approaches such as 12-step support, anger management, and brief intervention, the facility serves women, men, clients with dual diagnoses, and those involved with the criminal justice system. Committed to providing high-quality care and individualized support, the Inova CATS Program plays a vital role in assisting individuals on their journey to recovery.

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Falls Church, VA

The Inova CATS Program, situated in Falls Church, VA, provides extensive care for adults and young adults battling addiction. This institution excels in hospital-based inpatient detoxification and treatment for substance use disorders, including when mental health issues are also present. Employing approaches like 12-step facilitation, cognitive behavioral therapy, and brief interventions, the program customizes treatment plans to suit each person's specific requirements. Distinctive offerings for adult men, women, and those affected by intimate partner or domestic violence highlight the program's specialized approach. Offering round-the-clock support in a nurturing setting, the Inova CATS Program is committed to delivering high-quality, empathetic assistance to those on their path to recovery.

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Insight Human Services, situated in Asheville, NC, delivers tailored recovery programs for adult women, older adults, and young adults grappling with substance use disorders. The center's offerings encompass intensive outpatient care, day treatment, and general outpatient services, specifically designed for individuals managing co-occurring mental health conditions and addiction. Employing therapeutic approaches such as cognitive behavioral therapy, anger management, and motivational incentives, the facility addresses the unique needs of clients who have faced intimate partner violence, domestic abuse, or sexual trauma. Insight Human Services is committed to providing effective rehabilitation and compassionate support through its individualized treatment plans.

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Insight Treatment Centers, located in Suitland, MD, provides tailored programs for individuals dealing with substance use and accompanying mental health issues. They serve both adults and younger individuals. Their treatment modalities include intensive outpatient, standard outpatient, and step-down care, all personalized to each client's needs. Therapeutic methods utilized are 12-step integration, anger management techniques, and cognitive behavioral therapy. The center is equipped to support individuals with dual diagnoses and those involved with the legal system. Open to all genders, Insight Treatment Centers is dedicated to delivering effective support and high-caliber services for anyone pursuing healing from addiction and mental health concerns.

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Situated in Detroit, MI, the Institute of Supportive Services Inc delivers an extensive selection of treatment alternatives for those facing challenges with substance use and concurrent mental health issues. This facility features intensive outpatient care, general outpatient services, and day treatment/partial hospitalization programs. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention strategies, the center serves a diverse population, including adults, adolescents, and children, with tailored programs for active duty military personnel, adult males, and various age and gender demographics. The Institute of Supportive Services Inc is committed to offering exceptional care and assistance to support individuals in achieving enduring recovery.

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Institutes for Behavior Resources Inc, situated in Baltimore, MD, provides a full spectrum of care for individuals struggling with substance misuse. They are particularly adept at addressing dual diagnoses, namely the presence of both substance use disorders and significant mental health conditions in adults, as well as serious emotional challenges in young people. Their treatment offerings include structured intensive outpatient programs, flexible outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing scientifically validated methods such as cognitive behavioral therapy, contingency management, and motivational interviewing, the center serves adult men and women, including survivors of intimate partner or domestic violence. Their commitment extends to adults and young adults across genders, ensuring a nurturing setting for recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)