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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Integrative Life Center

Integrative Life Center in Nashville, TN, delivers a thorough spectrum of care for those pursuing freedom from substance abuse and accompanying mental health challenges. The center features tailored treatment plans for adult men and women, including those impacted by trauma. Offering flexible care options like intensive outpatient and day treatment programs, the facility serves adults and young adults of all genders. Employing proven methods such as 12-step integration, cognitive behavioral therapy, and the Matrix Model, this establishment guarantees excellent support for individuals embarking on their path to wellness and sustained sobriety.

Integrity Inc
Newark, NJ

Situated in Newark, NJ, Integrity Inc delivers exceptional rehabilitation solutions for adult males facing challenges related to substance abuse and concurrent severe mental health conditions. The center features both long and short-term residential options and emphasizes 12-step programs, anger management strategies, and brief intervention techniques. Focusing on individuals who have undergone intimate partner violence, domestic violence, or sexual trauma, Integrity Inc serves a diverse clientele, including adults, seniors, and younger adults. The facility's dedication to personalized care and high-standard programs establishes it as a reliable option for individuals looking for thorough and impactful addiction recovery services.

Integrity Inc
Newark, NJ

Situated in Newark, NJ, Integrity Inc provides extended residential treatment options for both adults and young adults aiming to address substance use issues. This center is dedicated to assisting individuals coping with co-occurring substance use disorders and significant mental health conditions in adults, as well as severe emotional challenges in children. Emphasizing support for female clients, the facility offers tailored programs for women who have undergone intimate partner violence, domestic abuse, or sexual trauma. By implementing methods such as 12-step facilitation, anger management techniques, and short-term interventions, Integrity Inc guarantees comprehensive care for adults, seniors, and young adults striving to conquer addiction and mental health difficulties.

Integrity Inc
Newark, NJ

Situated in Newark, NJ, Integrity Inc is dedicated to providing long-term residential care and round-the-clock support for adult males facing challenges with substance use disorders alongside significant mental health concerns or emotional issues. Emphasizing 12-step methods, anger management techniques, and short-term intervention strategies, this center designs custom programs for individuals who have suffered from intimate partner violence, domestic violence, or sexual trauma. Catering to adults, including seniors and young adults, Integrity Inc distinguishes itself by concentrating solely on male clients, thereby fostering a focused and nurturing atmosphere conducive to recovery. Discover thorough care and personalized treatment at this esteemed rehabilitation facility.

Integrity Inc
Newark, NJ

Integrity Inc, situated in Newark, NJ, provides extensive programs for adult men battling addiction within a long-term residential framework. This facility excels in substance abuse treatment and offers supportive housing, accommodating individuals who also face mental health challenges. Recovery is facilitated through methods such as 12-step encouragement, techniques for managing anger, and concise therapeutic interventions. Tailored services are available for adult men, those who have experienced sexual abuse, and clients with dual diagnoses. Committed to high standards of care, Integrity Inc assists adults, older adults, and young adults in finding a nurturing space for recovery and personal growth.

Integrity Inc
Newark, NJ

Integrity Inc, situated in Newark, NJ, is dedicated to offering targeted recovery support for adult women facing challenges with substance use and co-occurring severe mental health concerns. The center delivers comprehensive outpatient care, including intensive and day treatment, employing methodologies like 12-step integration, emotional regulation training, and concise counseling. Specialized programs are designed for individuals with histories of intimate partner violence, domestic abuse, and sexual trauma. Primarily serving adult women, including seniors and young adults, Integrity Inc is committed to delivering high-quality assistance and fostering healing for all clients on their path to wellness.

Integrity Inc
Newark, NJ

Integrity Inc, located in Newark, NJ, provides exceptional substance abuse treatment for adult women. They offer extended residential care, emphasizing transitional living, halfway house accommodations, and sober living environments. The center is adept at addressing dual diagnoses, treating addiction concurrently with significant mental health conditions in adults and emotional challenges in children. Integrity Inc also features unique programs for survivors of intimate partner violence, domestic abuse, and sexual assault, fostering a secure and nurturing space for healing. Their individualized strategies, incorporating 12-step guidance, anger control techniques, and short-term interventions, deliver thorough rehabilitation for adults, older adults, and young adults.

Inter Care Ltd
New York, NY

Inter Care Ltd in New York, NY, delivers focused recovery support for addiction and related mental health challenges. Their offerings include structured outpatient care, general outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing approaches like 12-step engagement, brief counseling, and cognitive behavioral techniques, Inter Care Ltd supports adult males, those with trauma histories, and individuals managing dual diagnoses. Open to adult men and women, as well as young adults, the center personalizes treatment plans to meet the distinct requirements of every person seeking help.

Integrated Care of Greater Hickory

Integrated Care of Greater Hickory, situated in Hickory, NC, provides extensive support for adults and young adults facing addiction. Their offerings encompass detox, outpatient care for substance misuse, and transitional living arrangements like halfway and sober houses. The facility is equipped to serve specific groups, including active military, adult men, and adult women, tailoring their approach. Recovery is fostered through methods such as 12-step facilitation, anger management, and brief interventions. They also offer outpatient treatment with methadone, buprenorphine, or naltrexone. Committed to high standards of care and personalized assistance, this center aims to guide individuals toward sustained recovery.

Integrity Behavioral Management

Integrity Behavioral Management located in New Orleans, LA, specializes in treatment for substance use and co-occurring disorders for both adults and children. Emphasizing personalized care, the center offers a variety of treatment modalities including intensive outpatient, outpatient, and day programs. The facility implements strategies such as 12-step recovery, anger management, and brief interventions, customizing its services to fit the specific requirements of each client. Catering to both men and women, Integrity Behavioral Management is recognized for its holistic approach in tackling substance use and mental health challenges. For those looking for high-quality care in a nurturing setting, this center is committed to supporting your journey towards long-term recovery.

Integrity House
Toms River, NJ

Integrity House, located in Toms River, NJ, provides a wide array of treatment options for substance use disorders, including intensive outpatient programs, standard outpatient services, and day treatment sessions. The facility emphasizes methodologies like 12-step facilitation, anger management techniques, and brief intervention strategies. Primarily focusing on adult men and women, as well as clients who have undergone sexual abuse, Integrity House serves a varied clientele. Accommodating individuals across all gender identities, the center customizes its approach to align with the specific requirements of each client. Its dedication to delivering high-quality care and specialized treatment options positions it as a leading facility for those in search of compassionate and effective addiction recovery solutions.

Integrity Inc
Secaucus, NJ

Integrity Inc, located in Secaucus, NJ, delivers an extensive array of rehabilitation services designed for individuals facing challenges related to substance use disorders alongside concurrent mental health issues. This center features intensive outpatient care, long-term residential options, and various outpatient programs that integrate methodologies such as 12-step facilitation, anger management, and brief interventions. Specialized programs are available for adult men and women, as well as those who have faced intimate partner violence. Emphasizing support for both adults and young adults, the facility creates a nurturing atmosphere for individuals on their journey to recovery. With a strong dedication to exceptional care and individualized treatment plans, Integrity Inc stands out as a reliable option for those seeking rehabilitation services.

Integrity Inc
Secaucus, NJ

Integrity Inc located in Secaucus, NJ, provides exceptional rehabilitation services for individuals dealing with substance abuse and co-occurring mental health disorders, catering to both adults and children. The center offers both residential and short-term residential programs, incorporating techniques such as 12-step facilitation, anger management, and brief intervention strategies. Tailored programs are available for adult men and women, as well as those who have faced intimate partner violence. This facility is committed to delivering quality care and personalized treatment to promote sustained recovery for adults and young adults of all genders. For those seeking specialized and effective rehabilitation in a nurturing atmosphere, Integrity Inc is ready to assist you.

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Nashua, NH

Integrate, located in Nashua, NH, delivers extensive addiction treatment options such as intensive outpatient programs, supervised living accommodations, and daily outpatient care. The center focuses on therapeutic interventions including 12-step support, managing anger, and brief counseling strategies for overcoming dependency. Catering to adult men, adult women, and the LGBTQ+ community, Integrate fosters a welcoming atmosphere for diverse individuals. This facility supports adults and young adults, providing specific attention to both male and female patients. Discover effective treatment and customized guidance at Integrate to begin a path to sustained sobriety.

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Integrated Care of Greater Hickory, located in Gastonia, NC, provides an extensive array of services for those battling addiction. This center offers detox services, treatment for substance use disorders, transitional living, and sober housing tailored for both men and women. It features outpatient options, including methadone and buprenorphine treatments, designed for adults and young adults in need of focused support. Their methodology incorporates 12-step programs, anger management strategies, and short-term interventions to assist individuals on the path to recovery. Additionally, they have specialized programs for active duty service members. Integrated Care of Greater Hickory is committed to delivering personalized, high-quality treatment aimed at helping clients achieve sustainable sobriety.

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Situated in Montrose, CO, Integrated Insight Community Care delivers specialized outpatient treatment for substance use issues affecting both adults and seniors. The center excels in addressing co-occurring substance use and significant mental health conditions, providing personalized care through methods such as cognitive behavioral therapy and anger management. With a commitment to customizing programs to meet individual needs, this facility is distinguished by its emphasis on a tailored approach. It offers outpatient services for methadone, buprenorphine, and naltrexone, serving both male and female clients in pursuit of effective and all-encompassing rehabilitation solutions.

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Situated in Delta, CO, Integrated Insight Therapy delivers extensive treatment for substance use and provides transitional housing for both adults and seniors. The center has a strong emphasis on addressing co-occurring disorders involving substance use and significant mental health challenges in adults, along with severe emotional issues in children. The treatment options include intensive outpatient programs, general outpatient services, and outpatient medication-assisted therapies using methadone, buprenorphine, or naltrexone. The center's methodology incorporates strategies such as anger management, brief interventions, and cognitive behavioral therapy, customizing its services to meet the distinct needs of each client. Integrated Insight Therapy ensures a specialized treatment experience for both men and women, prioritizing exceptional care for individuals on their path to recovery.

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Integrated Psychotherapeutic Services, located in Dallas, TX, delivers a wide range of treatment options for addiction that encompass detoxification and substance use therapies. This center provides a structured environment for intensive outpatient, outpatient, and detox services customized for both adults and young adults. Emphasizing techniques such as anger management, cognitive behavioral therapy, and strategies for preventing relapse, the facility attends to the specific requirements of clients dealing with co-occurring conditions involving pain and substance use, including those within the criminal justice system. With dedicated programs for adult women and personalized care for all clients, Integrated Psychotherapeutic Services is committed to offering effective support for individuals on their journey to recovery from addiction.

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Integrative Wellness LLC, located in Lebanon, IN, specializes in outpatient treatment for adults dealing with substance use issues alongside mental health challenges, as well as for children facing significant emotional difficulties. The facility offers treatment options including methadone, buprenorphine, and naltrexone, combined with ongoing outpatient services. The therapeutic strategies employed, such as brief interventions, cognitive behavioral therapy, and the Matrix Model, are customized to meet the specific needs of each patient. Catering to adults and seniors of all genders, Integrative Wellness LLC is distinguished by its personalized treatment approach, ensuring that individuals receive top-notch care in a nurturing atmosphere for their addiction recovery journey.

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Newark, NJ

Integrity House in Newark, NJ, delivers extensive care for individuals of all ages struggling with addiction, including those facing simultaneous serious mental health challenges. Their programs encompass intensive outpatient, outpatient, and standard outpatient care, all grounded in proven therapeutic methods like 12-step support, brief counseling, and cognitive behavioral strategies. Specialized treatment tracks are offered for adult men, women, those affected by intimate partner violence, and survivors of domestic abuse. Serving adults and older adults, regardless of gender, Integrity House is dedicated to providing exceptional support centered on complete well-being and lasting sobriety.

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Morris Plains, NJ

Situated in Morris Plains, NJ, Integrity Inc delivers thorough treatment for substance use and distinct care for those facing both substance use disorders and significant mental health challenges. The center features various outpatient services such as intensive outpatient programs and day treatment options. Emphasizing 12-step facilitation, anger management, and short-term interventions, Integrity Inc customizes its offerings to address the specific needs of each client. Additionally, the center provides specialized programs tailored for active duty military members, as well as separate tracks for adult men and women. This facility caters to adults and young adults of all genders, ensuring high-quality, individualized support for sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)