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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Intermountain Hospital of Boise

Intermountain Hospital of Boise, located in Boise, ID, provides extensive services for detoxification, substance abuse, and concurrent mental health disorders for both adults and children. Their inpatient hospital programs ensure around-the-clock support, employing techniques such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. This center accommodates active military personnel, teenagers, and adult males, with tailored programs designed for each demographic. Intermountain Hospital of Boise serves individuals of all genders across the adult and child/adolescent spectrum, prioritizing high-quality, personalized treatment to assist patients in achieving sustainable recovery from addiction and mental health issues.

Interval Brotherhood Homes Inc

Interval Brotherhood Homes Inc, situated in Akron, OH, provides an extensive range of services for those battling substance use disorders, along with transitional housing. This center focuses on adults facing both substance use challenges and significant mental health concerns. Emphasizing methods such as 12-step programs, anger management, and short-term interventions, the facility serves adult men, women, and young adults who have undergone trauma. With offerings that include inpatient hospital services, long-term residential care, and sober living arrangements, this center is committed to delivering high-quality support to individuals on their recovery journey in a nurturing atmosphere.

Interim House Inc
Philadelphia, PA

Interim House Inc, located in Philadelphia, PA, specializes in extensive substance abuse treatment and transitional living arrangements tailored for adult women. This center offers a range of services such as intensive outpatient care, long-term residential programs, and outpatient services, concentrating on areas like anger management, motivational interviewing, and relapse prevention strategies. With a particular focus on co-occurring mental health issues, the facility addresses the needs of clients with intricate backgrounds, including those connected to the criminal justice system. Catering to women of various ages, from young adults to seniors, Interim House Inc fosters a supportive and gender-sensitive atmosphere for those on their recovery and rehabilitation journey.

Intermountain
Salt Lake City, UT

Intermountain, located in Salt Lake City, UT, provides a broad spectrum of treatment options for adults and young adults dealing with substance use issues alongside significant mental health challenges or emotional struggles. The center features intensive outpatient and outpatient programs, as well as targeted treatments using methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief intervention strategies, and cognitive behavioral therapy, the facility serves adult men and women, including those who have undergone traumatic experiences. Intermountain is committed to delivering high-quality care to individuals pursuing tailored addiction recovery in a nurturing setting.

Intermountain
Salt Lake City, UT

Intermountain, situated in Salt Lake City, UT, delivers an extensive range of services for those struggling with substance use disorders and related mental health challenges in adults, along with addressing significant emotional issues in children. The center features various treatment options, including intensive outpatient, outpatient, and medication-assisted programs using methadone, buprenorphine, or naltrexone. Emphasizing strategies such as anger management, brief interventions, and cognitive behavioral therapy, Intermountain serves both men and women, as well as individuals who have faced traumatic experiences. This facility is dedicated to offering personalized care and research-supported therapies to facilitate sustainable recovery for adults and young adults of all genders.

InterCare Community Health Network

InterCare Community Health Network in Bangor, MI, delivers targeted care for adults facing substance use disorders alongside serious mental health conditions or emotional challenges in children. Their services include robust outpatient, intensive outpatient, and medication-assisted treatment options (methadone, buprenorphine, naltrexone). Emphasizing 12-step principles, anger management, and brief intervention strategies, the center supports a diverse clientele, including military personnel, youth, adult men, and seniors. Dedicated tracks for men and women ensure individualized attention. InterCare Community Health Network is committed to offering top-tier, holistic rehabilitation to guide individuals toward lasting recovery.

InterCommunity Healthcare
East Hartford, CT

InterCommunity Healthcare, located in East Hartford, CT, delivers extensive treatment for substance use disorders in adults, with a focus on those facing concurrent serious mental health issues. The center features a variety of treatment options, such as intensive outpatient and outpatient programs, with specific therapies including methadone/buprenorphine and naltrexone. Their methodology encompasses anger management, brief interventions, and cognitive behavioral therapy. Special programs are designed for adult men, women, and survivors of intimate partner violence. Catering to adults and seniors across all genders, InterCommunity Healthcare ensures customized support for each person. Committed to high-quality care and proven treatment methods, this center is recognized as a reliable source for addiction recovery services.

InterCommunity Healthcare

InterCommunity Healthcare, located in Hartford, CT, specializes in comprehensive detoxification and treatment for substance use within a nurturing setting. The center features residential detox services and round-the-clock care, employing proven methods including 12-step support, brief interventions, and cognitive behavioral therapy. InterCommunity Healthcare provides tailored programs for adult men and women, ensuring gender-sensitive treatment options for both sexes. Patients can anticipate individualized, high-quality care aimed at facilitating their recovery process.

InterCommunity Healthcare

InterCommunity Healthcare, located in Hartford, CT, provides a wide range of treatment options for adults and young adults dealing with both substance use disorders and significant mental health challenges. The center features specialized programs designed for men and women, offering various levels of care including short-term, long-term, and around-the-clock residential services. By employing proven methods such as cognitive behavioral therapy, 12-step programs, and targeted brief interventions, this facility effectively meets the needs of its diverse clientele. With a strong focus on high-quality care, gender-sensitive programming, and individualized treatment plans, InterCommunity Healthcare stands out as an excellent choice for those in need of effective rehabilitation solutions in the Hartford region.

InterCommunity Inc
Hartford, CT

InterCommunity Inc located in Hartford, CT provides extensive outpatient and intensive outpatient treatment for adults dealing with substance use issues alongside mental health challenges. Their services include cognitive behavioral therapy, anger management sessions, and short therapeutic interventions. The center tailors its approach to cater to adult men, women, and those who have faced trauma. Dedicated to serving adults and seniors of all genders, InterCommunity Inc prioritizes personalized care to address the distinct requirements of every individual. The center's all-encompassing treatment model and specialized offerings position it as an essential support for individuals pursuing effective rehabilitation in the Hartford vicinity.

InterCare Community Health Network

InterCare Community Health Network, located in Benton Harbor, MI, delivers targeted rehabilitation services for adults and seniors facing challenges related to substance use disorders and concurrent mental health issues. The facility offers a range of options, including intensive outpatient programs, standard outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, anger management, and brief intervention strategies, InterCare customizes its offerings to address the specific needs of each client. The center features specialized programs for active-duty military members, teenagers, and adult males, ensuring that both men and women receive all-encompassing care from qualified professionals committed to delivering effective treatment and assistance.

Intermountain Centers for

Intermountain Centers, located in Tucson, AZ, provides thorough addiction recovery services and expert support for individuals with dual diagnoses, addressing both substance dependence and significant mental health conditions in adults, or serious emotional challenges in youth. They offer a range of treatment modalities, including intensive outpatient, extended residential stays, and standard outpatient services. The center employs scientifically validated techniques such as anger management, cognitive behavioral therapy, and community reinforcement with incentive programs. Additionally, they feature specific interventions for adolescents, survivors of intimate partner violence, domestic abuse, and sexual assault, delivering customized care for young males and females. Clients can anticipate high standards of care and personalized recovery strategies at Intermountain Centers.

Intermountain Centers for

Intermountain Centers for in Tucson, AZ, delivers expert substance abuse care in a secure and encouraging setting. Prioritizing inpatient services, with both round-the-clock and brief stays available, this establishment features customized plans for patients across the lifespan, from children to adults. Their methodology integrates techniques like anger reduction, immediate support, and cognitive restructuring to meet unique requirements effectively. Distinctive offerings include dedicated tracks for individuals with a history of trauma and those facing dual diagnoses of mental health and addiction challenges. Through dedication to high standards, Intermountain Centers for guarantees a thorough and empathetic path to recovery for all individuals, regardless of gender, pursuing freedom from substance dependency.

InterCare Community Health Network

InterCare Community Health Network, located in Eau Claire, MI, delivers targeted substance abuse treatment for adults grappling with serious mental health issues alongside children experiencing emotional challenges. Their outpatient services feature intensive treatment alternatives, as well as methadone, buprenorphine, and naltrexone therapies. By utilizing techniques such as 12-step facilitation and anger management, the center offers personalized care for active military members, teenagers, and adult males. Catering to adults and seniors of various genders, InterCare Community Health Network provides extensive and impactful rehabilitation programs for individuals pursuing exceptional addiction recovery in a nurturing atmosphere.

Inter Care Ltd
Hawthorne, NY

Inter Care Ltd, situated in Hawthorne, NY, delivers extensive support for individuals of all ages struggling with addiction and co-occurring mental health challenges. Their diverse offerings, such as intensive outpatient programs and outpatient medication-assisted treatment (methadone/buprenorphine), allow for personalized care plans. Employing proven methodologies like 12-step integration and cognitive behavioral therapy, Inter Care Ltd is dedicated to providing effective, scientifically-backed interventions. Specific programs are designed for adult men, individuals with a history of trauma, and those facing dual diagnoses. Serving both men and women, the facility is committed to fostering complete wellness and sustained sobriety.

Intercept True North Health Clinic

Intercept True North Health Clinic in Roanoke, VA, offers a comprehensive range of services for individuals seeking recovery from substance use disorders and co-occurring mental health conditions. Their treatment programs include detoxification, substance use treatment, and specialized care for those with serious mental health illnesses. The center provides intensive outpatient treatment, outpatient detoxification, and outpatient services utilizing approaches such as 12-step facilitation, anger management, and brief intervention. With a focus on adolescents, adults, and seniors of all genders, Intercept True North Health Clinic delivers high-quality care tailored to each individual's unique needs.

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InterCare Community Health Network, located in Holland, MI, specializes in providing substance use rehabilitation for adults facing significant mental health challenges alongside children with profound emotional issues. The outpatient services feature intensive programs, as well as treatments involving methadone, buprenorphine, or naltrexone. The center customizes its approaches, offering various interventions like 12-step support, anger management strategies, and short-term counseling. Among its distinct offerings are tailored services for active military members, youth, and adult males. InterCare Community Health Network is dedicated to delivering comprehensive care to adults and seniors of every gender, prioritizing individualized treatment strategies that promote enduring recovery.

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InterCare Community Health Network, located in Pullman, MI, delivers a full spectrum of substance abuse support for adults facing co-occurring serious mental health challenges and for children with significant emotional disturbances. Their services include robust intensive outpatient programs, general outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The facility is equipped to assist specific groups with dedicated programs for active military personnel, teenagers, and adult males, demonstrating their commitment to varied populations. Utilizing methods like 12-step facilitation, anger management techniques, and brief intervention strategies, InterCare Community Health Network focuses on personalized recovery journeys. Serving adults and older adults of any gender, this organization emphasizes high-quality, individually crafted treatment approaches.

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Dorchester Center, MA

Interim House Inc, located in Dorchester Center, MA, provides a long-term residential treatment program for adult men dealing with substance use disorders in a nurturing and secure atmosphere. This center features transitional housing and sober living arrangements, with round-the-clock support available. Employing various methods, including 12-step programs, anger management techniques, and brief interventions, the treatment is customized to meet the specific needs of each individual. The center also offers unique programs aimed at adult men who have faced issues such as intimate partner violence, domestic abuse, and sexual trauma. Focusing on adult males, including seniors and younger adults, Interim House Inc ensures that each client receives personalized care. The center is committed to delivering high-quality, evidence-driven treatment for individuals striving to defeat addiction and restore their lives.

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Philadelphia, PA

Interim House West Inc. in Philadelphia, PA, provides dedicated long-term residential care for adult women facing challenges with substance use and co-occurring serious mental health concerns. This establishment fosters a nurturing atmosphere for individuals who have endured intimate partner violence, domestic abuse, or sexual trauma. Their approach incorporates 12-step support, strategies for managing anger, and cognitive-behavioral techniques, all customized to each client's unique journey. Through residential detox and continuous round-the-clock support, the center ensures thorough assistance in the recovery process. Catering to adults, older adults, and younger adults, this facility is committed to delivering high-caliber care and empowering women on their quest for wellness and sustained sobriety.

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Intermountain Health Centers Inc., located in Nogales, AZ, delivers outpatient substance abuse recovery services and tailored support for those experiencing co-occurring mental health challenges. The facility employs standard outpatient treatment methodologies, including anger management techniques, brief intervention strategies, and cognitive behavioral therapy. Specifically designed for individuals with dual diagnoses, this program serves adults and seniors across all genders. Intermountain Health Centers Inc. is recognized for its thorough approach to treating individuals grappling with significant emotional distress and substance dependency. Patients can anticipate receiving excellent care and personalized assistance within a warm and proficient setting.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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