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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Jaywalker Lodge Inc
Carbondale, CO

Situated in Carbondale, CO, Jaywalker Lodge Inc provides extended residential and around-the-clock substance abuse recovery services specifically for adult males. The facility emphasizes techniques like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. It features specialized programs tailored for adult men, individuals who have faced sexual abuse, and those with trauma backgrounds. This center serves men of all ages, including older adults and younger individuals, creating a nurturing atmosphere dedicated solely to male clients. By prioritizing evidence-based practices and individualized care, Jaywalker Lodge Inc distinguishes itself through its wide-ranging treatment offerings and dedication to aiding individuals on their recovery journey.

Jefferson Health
Cherry Hill, NJ

Jefferson Health, situated in Cherry Hill, NJ, delivers targeted care for adults facing dual diagnoses of severe mental health conditions and substance use disorders, as well as for children with significant emotional challenges. Their program offerings include structured intensive outpatient care, general outpatient services, and day treatment or partial hospitalization. Employing evidence-based methods such as 12-step integration, anger management techniques, and brief intervention strategies, this establishment is equipped to assist individuals managing overlapping mental health and addiction issues. Jefferson Health is committed to offering high-caliber treatment and thorough assistance to people of all genders, encompassing adults and younger individuals, who are striving for recovery from addiction and mental health struggles.

Jerry L Pettis Memorial VA Med Center

At the Jerry L Pettis Memorial VA Med Center in Loma Linda, CA, adults and young adults can access dedicated programs for overcoming substance use challenges. This center delivers robust outpatient services, including intensive programs and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their therapeutic interventions emphasize anger management, cognitive behavioral therapy, and contingency management, specifically addressing the needs of those who have experienced trauma, sexual abuse, or are managing co-occurring mental health and substance use conditions. The center welcomes both male and female participants, reflecting a holistic and inclusive philosophy. Discover effective treatment and personalized assistance at this respected rehabilitation facility.

Jersey Shore Medical Center

Jersey Shore Medical Center, situated in Neptune, NJ, delivers extensive recovery programs for adults and adolescents facing addiction and coexisting mental health challenges. The center features intensive outpatient and general outpatient programs, alongside medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing proven therapeutic approaches such as cognitive behavioral therapy and contingency management, the center customizes care strategies for each person. Catering specifically to individuals with dual diagnoses, Jersey Shore Medical Center offers dedicated services for both male and female clients. For those in search of impactful, individualized addiction treatment within a nurturing setting, this institution is committed to supporting your journey toward lasting sobriety.

Janus of Santa Cruz
Santa Cruz, CA

Janus of Santa Cruz, located in Santa Cruz, CA, provides exceptional detoxification and addiction treatment services within a nurturing setting. The center offers an array of treatment options such as long-term residential programs, detox services, and round-the-clock residential support. Its expertise includes 12-step programs, brief intervention strategies, and cognitive behavioral therapy. Specialized programs are available for individuals who have dealt with trauma and those facing dual diagnoses of mental health and substance use issues. Janus of Santa Cruz caters to both adult and young adult demographics, ensuring personalized care for all genders.

Janus of Santa Cruz
Santa Cruz, CA

Situated in Santa Cruz, California, Janus of Santa Cruz specializes in substance use rehabilitation for women. The center offers various treatment options, including long-term residential care, 24-hour residential programs, and short-term stays. By employing proven methods such as 12-step programs, brief interventions, and cognitive behavioral techniques, this facility is particularly suited for those who have faced intimate partner violence, domestic abuse, and trauma. Janus of Santa Cruz is committed to delivering personalized services for adults, seniors, and young adults, fostering a nurturing atmosphere aimed at recovery and healing.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, located in Wheat Ridge, CO, specializes in addressing substance use disorders along with serious mental health challenges in adults, as well as emotional issues in children. The center emphasizes intensive outpatient programs and offers outpatient options like methadone, buprenorphine, or naltrexone therapy. It employs personalized treatment methodologies such as cognitive behavioral therapy and motivational interviewing. Additionally, the center features distinct programs designed for active military members, adolescents, and adult males. Committed to providing exceptional care, the center supports adults and seniors across all genders, ensuring customized rehabilitation services for those in need.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, situated in Wheat Ridge, CO, delivers a wide array of services for people seeking assistance with substance misuse and concurrent significant mental health issues. This center features intensive outpatient programs, standard outpatient care, and outpatient treatments using methadone/buprenorphine or naltrexone. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, the facility addresses the needs of both adults and children facing severe emotional challenges. Additionally, specialized programs are available for active military members, young individuals, and men. Committed to offering personalized and high-quality care for adults and seniors of all genders, the Jefferson Center for Mental Health aims to facilitate recovery and enhance overall well-being.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, located in Denver, CO, delivers extensive support for addiction and co-occurring mental health conditions, serving individuals of all ages. Dedicated services are available for active military personnel, young people, and adult men. The center employs proven therapeutic methods, including cognitive behavioral therapy and motivational interviewing, within its intensive outpatient and outpatient programs. Care is personalized, with distinct programs designed for adults, seniors, and separate options for male and female patients. The Jefferson Center for Mental Health is recognized for its dedication to high-quality, nurturing rehabilitation services in the Denver region.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, situated in Denver, Colorado, provides an extensive array of treatment alternatives for those dealing with substance use issues alongside mental health challenges. This facility includes intensive outpatient care, outpatient services, and targeted programs featuring methadone, buprenorphine, or naltrexone. Emphasizing brief intervention strategies, cognitive behavioral therapy, and motivational interviewing, it supports both adults and children grappling with significant emotional difficulties. Additionally, specialized programs are available for active military members, teenagers, and adult males. The center is dedicated to serving individuals of all genders, including adults and seniors, ensuring personalized care and assistance for everyone.

Jefferson Center for Mental Health

Situated in Denver, CO, the Jefferson Center for Mental Health provides targeted support for individuals dealing with substance use disorders and simultaneous mental health challenges, catering to both adults and children. The center features both intensive outpatient and outpatient options, such as methadone and buprenorphine therapies, offering customized treatment through approaches like brief interventions, cognitive behavioral therapy, and motivational interviewing. Specialized programs are available for active military personnel, adolescents, and adult men to address their specific requirements. This facility serves a diverse population, including adults and seniors of all genders, ensuring comprehensive and high-quality care for those in need of addiction recovery and mental health assistance.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, situated in Wheat Ridge, CO, delivers a comprehensive suite of targeted therapies for individuals grappling with substance use and intertwined mental health conditions, serving both adolescents and adults. Their offerings include robust intensive outpatient programs, standard outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing strategies like brief intervention, cognitive behavioral therapy, and motivational interviewing, the center personalizes care plans for every client. Dedicated programs are available for active duty military members, teenagers, and adult men. Open to adults and older adults of all gender identities, the facility is committed to providing superior support throughout the recovery journey.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health in Denver, CO, provides specialized services for adults and seniors dealing with addiction and co-occurring mental health challenges. They offer intensive outpatient and standard outpatient programs, employing proven methods like cognitive behavioral therapy and motivational interviewing. Distinctive offerings are available for active military members, young people, and adult men. Emphasizing high standards of care, the center delivers gender-tailored treatment for men and women. For those needing assistance with substance dependence or significant emotional distress, this respected institution offers personalized support.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, situated in Black Hawk, CO, provides extensive support for individuals battling substance use and co-occurring mental health conditions. They extend their services to both adults and younger individuals, emphasizing intensive outpatient services alongside methadone and buprenorphine treatment. Their approach incorporates evidence-based methods like brief interventions, cognitive behavioral therapy, and motivational interviewing to create personalized treatment plans. Dedicated programs are available for active-duty service members, teenagers, and adult men. Serving a diverse population including seniors, this center is committed to delivering exceptional, person-centered care aimed at fostering sustained recovery and overall mental well-being.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, located in Arvada, CO, provides targeted treatment for individuals dealing with substance abuse and co-occurring mental health challenges, serving both adults and children. Their extensive offerings feature intensive outpatient and outpatient programs that emphasize evidence-based techniques like cognitive behavioral therapy and motivational interviewing. This center also delivers customized care for active military members, youth, and men, ensuring support for all adults and older adults regardless of gender. With a strong dedication to delivering high-quality care and personalized treatment strategies, the Jefferson Center for Mental Health strives to assist clients in their recovery journey.

Jefferson Center for Mental Health

The Jefferson Center for Mental Health, located in Evergreen, CO, specializes in providing treatment for substance use and co-occurring disorders for both adults facing severe mental health challenges and children dealing with emotional issues. The center offers a variety of treatment options, including intensive outpatient programs, traditional outpatient services, and medication-assisted therapies with methadone or buprenorphine. Their approach includes personalized care through strategies like brief interventions, cognitive behavioral therapy, and motivational interviewing. Distinctive programs are available for active duty military members, adolescents, and adult men, accommodating clients of all ages and genders. With a commitment to high-quality care and a focus on customized treatment plans, this center stands out as a leading option for those in need of thorough rehabilitation services in the Evergreen region.

Jefferson Center for Mental Health

Nestled in Idaho Springs, Colorado, the Jefferson Center for Mental Health provides dedicated support for individuals grappling with substance use disorders and co-occurring mental health challenges. Serving both young and adult populations, the center offers a comprehensive suite of intensive outpatient and traditional outpatient services, incorporating vital treatments such as methadone and buprenorphine. Their therapeutic framework is firmly rooted in scientifically validated methods, including cognitive behavioral therapy and motivational interviewing, to foster lasting change. Distinctive programs are available for active military members, teenagers, and adult males. Catering to individuals of all ages, from adults to seniors, and across all genders, the facility emphasizes personalized care pathways designed to promote successful recovery and overall mental well-being. Opt for the Jefferson Center for a complete and superior rehabilitation experience within a supportive setting.

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Situated in Corbin, KY, Jaynes Family Practice delivers a wide range of rehabilitation services designed for adults and senior individuals dealing with substance use issues along with concurrent mental health challenges. The center focuses on intensive outpatient care as well as outpatient options utilizing methadone/buprenorphine or naltrexone. Employing validated techniques such as cognitive behavioral therapy and anger management, the facility offers personalized treatment for women, particularly those impacted by intimate partner violence. Additionally, with specific programs geared towards active military members and young adults, this center is committed to providing high-quality care and support to those striving to conquer addiction and enhance their mental health.

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Carbondale, CO

Situated in Carbondale, CO, Jaywalker Lodge Inc specializes in addiction recovery for adult males within a nurturing atmosphere. The center features a range of treatment options, including intensive outpatient programs, long-term residential support, and outpatient services. Employing evidence-based methods such as cognitive behavioral therapy and motivational interviewing, Jaywalker Lodge Inc emphasizes the importance of 12-step facilitation. The facility is particularly beneficial for those who have faced trauma or sexual abuse. With customized programs for young adults, adults, and seniors, the center ensures holistic care for individuals across different life stages. For male clients in need of transitional housing or a halfway house, this center is recognized for its exceptional and empathetic rehabilitation offerings.

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Johnston, RI

Situated in Johnston, RI, Jellison House delivers tailored rehabilitation services aimed at adult males grappling with substance use issues alongside significant mental health challenges. The facility features inpatient hospital treatment, continuous round-the-clock care, and extended residential options. Emphasizing methods such as 12-step programs, anger management strategies, and concise intervention techniques, Jellison House is equipped to assist individuals who have faced intimate partner violence, domestic abuse, and sexual trauma. This center serves a diverse range of clients, including adults, seniors, and young adults, fostering a secure and nurturing environment for men pursuing personalized and thorough recovery support.

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Jeremiah Recovery House Inc, located in Berryville, AR, provides an extensive array of services for individuals dealing with substance use challenges. This center features transitional housing options, including halfway houses and sober living environments specifically designed for adult males and females. It offers various treatment modalities, such as intensive outpatient programs and daytime outpatient services, focusing on methods like 12-step engagement, anger management, and brief intervention strategies. Additionally, specialized programs are available for active military members, addressing the needs of both adults and younger individuals. The facility also emphasizes gender-specific treatment to ensure more personalized care. Jeremiah Recovery House Inc is dedicated to delivering high-quality, individualized recovery plans tailored to those on their journey toward overcoming addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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