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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Lake Hills Oasis
Somerset, KY

Located in Somerset, KY, Lake Hills Oasis provides extensive treatment for substance use disorders specifically designed for adult and older male clients. Emphasizing personalized care, the center offers a range of options including intensive outpatient, long-term residential, and outpatient services. Using methods like 12-step facilitation, anger management techniques, and brief interventions, Lake Hills Oasis customizes its approach to meet the unique requirements of each individual. This facility is distinguished by its dedication to tailored care and thorough attention to client needs. For those in search of effective addiction treatment that prioritizes personal circumstances, Lake Hills Oasis in Somerset is an excellent option for high-quality support.

Lakes Treatment Center Inc

Situated in Copperopolis, CA, Lakes Treatment Center Inc delivers extensive rehabilitation programs aimed at adults and young adults confronting substance abuse and related mental health disorders. This center offers long-term residential services, detoxification, and around-the-clock assistance. By employing methods like 12-step facilitation, anger management techniques, and cognitive behavioral therapy, the facility customizes its treatment to meet the specific needs of each individual. It features specialized programs designed for both adult men and women, as well as those who have faced intimate partner or domestic violence. Committed to high-quality care and individualized treatment strategies, Lakes Treatment Center Inc prioritizes helping clients navigate their recovery paths.

Lakes Treatment Center Inc

Nestled in Copperopolis, CA, Lakes Treatment Center Inc is dedicated to providing a full spectrum of care for those battling substance use disorders and accompanying mental health conditions. They offer extended residential stays, detox services, and round-the-clock residential assistance. Their approach emphasizes 12-step principles, anger management techniques, and cognitive behavioral therapy, ensuring a personalized treatment plan for every client. Dedicated programs cater to adult men and women, as well as individuals affected by domestic violence or intimate partner abuse. Serving adults and young adults of all genders, Lakes Treatment Center Inc is committed to delivering exceptional, individualized support for sustained recovery.

Lakeside Academy
Buffalo, MN

Situated in Buffalo, MN, Lakeside Academy delivers a wide array of rehabilitation services specifically designed for adult males. This center offers various treatment options, including intensive outpatient therapy, long-term residential support, and standard outpatient programs. Lakeside Academy focuses on addressing substance use disorders, alongside concurrent mental health challenges and emotional issues in adolescents. Emphasizing techniques such as 12-step empowerment, anger management, and brief interventions, the center customizes its methods to meet the specific requirements of each individual. Specialized programs for teenagers, as well as for those who have experienced domestic violence and sexual abuse, distinguish Lakeside Academy from other facilities. Dedicated to providing quality care and tailored services, this center strives to assist clients on their path to recovery.

Lakeside Behavioral Health System

Situated in Memphis, TN, Lakeside Behavioral Health System delivers extensive rehabilitation services tailored for adults and seniors. This facility specializes in detoxification, treatment for substance use disorders, and managing co-occurring conditions, providing inpatient care around the clock. Lakeside employs various methods such as 12-step programming, anger management techniques, and brief intervention strategies to meet the unique needs of each individual. The center also offers specialized programs for active duty military members, as well as distinct services for adult men and women, ensuring it serves a wide range of clients. With a strong commitment to high-quality care and personalized treatment approaches, Lakeside Behavioral Health System stands out as a premier option for specialized addiction and mental health support in the area.

Lake Whatcom Residential and Trt Ctr

Lake Whatcom Residential and Trt Ctr, located in Bellingham, WA, offers tailored care for individuals of all ages facing substance use and co-occurring mental health challenges. Within a peaceful residential environment, they provide flexible treatment durations, including extended, brief, and round-the-clock options. Their approach integrates proven methods such as 12-step support and emotional regulation techniques, customized for each person's journey. Specialized tracks are available for active military personnel, adult men, and women, emphasizing personalized support. Addressing the needs of adults and young adults, both male and female, Lake Whatcom Residential and Trt Ctr is dedicated to delivering thorough and effective services for sustained healing.

Lake Whatcom Residential and Trt Ctr

Lake Whatcom Residential and Trt Ctr, located in Bellingham, WA, delivers a full spectrum of recovery support. Their offerings encompass extended residential stays, standard outpatient care, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. They focus on aiding individuals through substance use recovery and providing stable housing during their transition. The facility excels in addressing dual diagnoses of substance abuse and significant mental health conditions in adults, as well as severe emotional challenges in children. Utilizing proven methods like motivational interviewing, cognitive behavioral therapy, and motivational incentives, Lake Whatcom Residential and Trt Ctr supports a broad range of clients, including active military, adult men and women, and young adults. They are dedicated to providing excellent, individualized care.

Lakeview Behavioral Health

Situated in Hibbing, MN, Lakeview Behavioral Health specializes in addressing substance abuse and mental health disorders concurrently for both adults and children. The facility offers various treatment options, including intensive outpatient, outpatient, and partial hospitalization, employing proven methods such as anger management, cognitive behavioral therapy, and motivational techniques. Lakeview Behavioral Health is equipped with customized programs for active military personnel, teenagers, and adult males, and it serves individuals of all genders, including seniors. Committed to delivering high-quality, personalized care, this center has earned a reputation as a reliable option for extensive rehabilitation services within the Hibbing community.

Lake Wellness Center

Situated in Covington, LA, Lake Wellness Center presents an extensive array of specialized rehabilitation services. The facility offers detox and treatment for substance use through various options, including intensive outpatient, outpatient, and partial hospitalization programs. Employing proven methods such as cognitive behavioral therapy and the Matrix Model, the center serves adult men and women, along with active duty military members. With an emphasis on short-term interventions and customized care, Lake Wellness Center is committed to aiding the recovery process for adults and young adults, providing tailored treatment plans for both genders.

Lake Wellness Center

Lake Wellness Center in Metairie, LA, is dedicated to providing extensive addiction treatment solutions for individuals striving for lasting sobriety. Their offerings encompass detox and comprehensive substance abuse therapy via intensive outpatient, outpatient, and day treatment formats. Employing therapeutic modalities like brief intervention, cognitive behavioral therapy, and the Matrix Model, Lake Wellness Center crafts personalized recovery plans. They also feature specialized programs designed for active duty military, adult men, and adult women, ensuring a broad spectrum of client needs are addressed. Serving adults and young adults, Lake Wellness Center is committed to delivering exceptional care and assistance to all on their journey to overcoming addiction.

Lake Wellness Center

Situated in Houma, Louisiana, Lake Wellness Center delivers a wide range of addiction recovery services for both adults and young adults. The facility specializes in detox and treatment for substance misuse, offering various programs including intensive outpatient, outpatient, and day treatment options. Employing evidence-based methods like brief intervention, cognitive behavioral therapy, and the Matrix Model, the center customizes treatment plans to meet the unique requirements of each individual. It also features specialized programs tailored for active duty military members, as well as programs for adult men and women. Committed to providing high-quality care, Lake Wellness Center fosters a nurturing atmosphere for all clients on their path to recovery.

Lakeview Behavioral Health

Lakeview Behavioral Health, located in Grand Rapids, MN, delivers extensive rehabilitation services to both adults and young adults facing challenges related to substance use and concurrent mental health disorders. The center features various treatment options including intensive outpatient programs, outpatient day programs, and personalized outpatient services. With dedicated programs designed for active military personnel, as well as specific services for adult men and women, Lakeview Behavioral Health serves a wide range of individuals. The facility employs research-backed methods such as cognitive behavioral therapy and contingency management, focusing on effective strategies like anger management. Deeply committed to providing high-quality care, this center fosters a nurturing environment for those on their path to recovery.

Lake Wellness Center

Lake Wellness Center, located in Lafayette, LA, provides a wide range of services for addiction recovery, encompassing detox and treatment for substance abuse. Their programs are designed to cater to the unique requirements of each individual, offering various formats such as intensive outpatient care, regular outpatient services, and day treatment options. Employing proven methods like brief intervention, cognitive behavioral therapy, and the Matrix Model, this center delivers excellent support for adult men, women, and active duty military members. Focusing on the rehabilitation of adults and young adults, Lake Wellness Center invites both male and female clients who are in search of effective recovery solutions within a nurturing atmosphere.

Lakeview Center Inc
Pensacola, FL

Lakeview Center Inc, located in Pensacola, FL, provides focused treatment for substance abuse and co-occurring mental health issues for both adults and youth. The center offers various residential options, including long-term and short-term stays, and utilizes methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Customized treatment programs are available for adults and adolescents, with gender-specific options for male and female clients. Lakeview Center Inc is recognized for its detailed treatment plans and high-quality care, ensuring that every participant receives individualized support as they work towards recovery.

Lakeside Family Therapy Services

"Lakeside Family Therapy Services in Racine, WI, offers outpatient treatment for substance use and co-occurring mental health conditions in adults and children. The center specializes in anger management, brief intervention, and cognitive behavioral therapy. Unique programs cater to active duty military, adolescents, adult men, as well as adults and seniors of all genders. With a focus on quality care, this facility provides a supportive environment for individuals seeking recovery. Whether seeking help for substance use or mental health concerns, Lakeside Family Therapy Services offers tailored treatment plans to meet the diverse needs of its clients."

Lake Place Retreat Center

Nestled in Bovey, MN, Lake Place Retreat Center provides robust outpatient and intensive outpatient programs designed for adult men addressing substance dependency. The center excels in employing the 12-step facilitation, Matrix Model, and relapse prevention strategies, offering thorough support. This institution serves adult men, including seniors and young adults, who have faced intimate partner violence, domestic abuse, and sexual trauma. By concentrating on individualized treatment plans for male patients, Lake Place Retreat Center cultivates a nurturing setting for healing. For those in pursuit of effective addiction treatment with a distinct specialization, this center presents a caring and successful route to recovery.

Lake Wellness Center
Baton Rouge, LA

Nestled in Baton Rouge, LA, Lake Wellness Center is a premier addiction treatment facility delivering a full spectrum of care. They offer crucial detoxification and substance abuse rehabilitation via structured intensive outpatient, standard outpatient, and day treatment options. Employing evidence-based methodologies including brief intervention, cognitive behavioral therapy, and the Matrix Model, this institution supports active duty military members, adult males, and adult females. Dedicated to serving adults and young adults, Lake Wellness Center prioritizes providing exceptional support for those on their journey to overcome substance use disorders.

Lake Wellness Center

Nestled in New Roads, LA, Lake Wellness Center provides extensive addiction recovery solutions for adults and young adults. Their offerings include detox and substance use treatment via intensive outpatient, outpatient, and day treatment modalities. Employing methods like brief intervention, cognitive behavioral therapy, and the Matrix Model, this establishment customizes care to each person's unique situation. Lake Wellness Center also caters to specific groups with dedicated programs for active duty military personnel, adult men, and adult women, guaranteeing specialized support. They welcome both male and female clients, focusing on high-quality, evidence-based approaches to aid individuals in their journey toward lasting sobriety.

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Situated in Devils Lake, ND, the Lake Region Human Service Center provides extensive treatment options for substance use disorders in both adults and children, particularly those dealing with concurrent mental health issues. Their program offerings include intensive outpatient and traditional outpatient services, employing proven methods such as cognitive behavioral therapy and motivational interviewing. The center prioritizes customized treatment plans that cater to the specific requirements of each individual. Emphasizing support and inclusivity, it serves adult and senior clients of all genders. For anyone in search of effective, personalized recovery solutions, the Lake Region Human Service Center is committed to delivering exceptional care to aid in your recovery journey.

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Nestled in Rolla, ND, Lake Region Outreach Office is dedicated to providing expert recovery assistance for adults and elderly individuals facing addiction and concurrent severe mental health challenges. The center features robust intensive outpatient and outpatient care, encompassing methadone/buprenorphine or naltrexone therapy. Emphasizing personalized attention, the facility employs scientifically proven methods like cognitive behavioral therapy and motivational interviewing. Lake Region Outreach Office distinguishes itself with customized plans designed to meet the specific requirements of every individual. Men and women looking for thorough substance abuse treatment within a nurturing setting will receive exceptional support here.

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Situated in Hollister, CA, Lakes Treatment Center Inc presents a wide array of targeted services aimed at helping individuals combat addiction. The center offers extensive options including long-term residential stays, detoxification programs, and 24-hour residential care designed for both adults and young adults. Emphasizing techniques like 12-step support, anger management, and cognitive behavioral therapy, this facility is recognized for its dedication to providing high-quality treatment. Additionally, Lakes Treatment Center Inc features specialized services for adult men and women, as well as those affected by domestic violence or intimate partner violence. Their welcoming approach ensures a nurturing atmosphere for all clients on their journey to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)