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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Lakeview Health Systems LLC

Lakeview Health Systems LLC, based in Jacksonville, FL, provides an extensive selection of addiction recovery services designed for both adults and young adults. The center features hospital inpatient detoxification and treatment, utilizing methods like 12-step facilitation and anger management. What sets this facility apart is its targeted programs for active military members, women, and those affected by intimate partner violence. Additionally, with options for transitional housing and treatment pathways specifically for each gender, Lakeview Health Systems LLC is dedicated to delivering personalized care that promotes effective and well-rounded recovery.

Lakewood Comprehensive Treatment Ctr

Lakewood Comprehensive Treatment Ctr, situated in Lakewood, WA, provides various outpatient services for substance use disorders. The facility offers treatments including methadone, buprenorphine, and naltrexone, utilizing effective methods such as brief interventions, cognitive behavioral therapy, and motivational incentives. It serves adult men and women, along with clients affected by intimate partner or domestic violence. With a commitment to cater to adults and young adults of all genders, this center emphasizes providing personalized care, making it an essential option for individuals seeking targeted addiction treatment solutions.

Lamprey Healthcare
Newmarket, NH

Lamprey Healthcare, situated in Newmarket, NH, is a full-service recovery facility dedicated to addressing substance use challenges in adults and young adults. They provide various levels of care, including outpatient services, medication-assisted treatment with methadone, buprenorphine, or naltrexone, and standard outpatient programs. Their therapeutic offerings encompass techniques like anger management, brief intervention, and cognitive behavioral therapy. Lamprey Healthcare serves adult men and women and supports individuals facing co-occurring mental health and substance use conditions. By emphasizing personalized attention and proven treatment methodologies, the center delivers effective recovery support for all patients.

Landmark Recovery
Indianapolis, IN

Landmark Recovery, located in Indianapolis, IN, provides a wide range of addiction recovery services for both adults and young adults. This center specializes in detoxification, treatment for substance use disorders, and offers dedicated support for those facing concurrent mental health conditions in adults or emotional issues in children. With a variety of treatment formats such as intensive outpatient, long-term residential, and outpatient care, Landmark Recovery customizes its services to meet the unique needs of each individual. The facility employs evidence-backed methods, including 12-step programs, cognitive behavioral therapy, and brief therapeutic interventions, to maintain a high standard of care. Additionally, there are specific programs aimed at active military members, as well as tailored options for adult men and women. Landmark Recovery is open to both male and female individuals in search of effective and personalized recovery solutions.

Landmark Recovery of Knoxville

Landmark Recovery of Knoxville, located in Seymour, TN, delivers extensive, research-backed therapeutic options for adults and young adults battling addiction and accompanying mental health challenges. The center features intensive outpatient, extended residential, and standard outpatient care, employing methods like 12-step guidance, cognitive behavioral therapy, and brief intervention strategies. Dedicated programs for active military personnel, adult men, and adult women are available, demonstrating Landmark Recovery of Knoxville's commitment to varied client requirements. Their customized treatment strategies and skilled professionals guarantee excellent care for all clients, establishing it as a premier destination for effective and individualized recovery assistance.

Landmark Recovery of Louisville

Landmark Recovery of Louisville in Louisville, KY, delivers extensive substance abuse rehabilitation for adults and young adults. Their offerings encompass detox services, drug and alcohol treatment, and tailored support for co-occurring mental health disorders. The center provides various treatment modalities, including intensive outpatient, residential stays, and flexible outpatient programs, to suit different requirements. Employing proven therapeutic strategies such as 12-step integration, cognitive behavioral therapy, and brief intervention techniques, Landmark Recovery ensures high-quality care. Additionally, they feature distinct programs designed for active military members, adult males, and adult females. A key focus at this facility is the development of personalized treatment strategies to aid every individual's path to recovery.

Lantana Recovery
Charleston, SC

Situated in Charleston, SC, Lantana Recovery provides targeted treatment for adults and young adults struggling with substance use and co-occurring mental health disorders. The center offers a range of services including intensive outpatient programs, outpatient treatments, and day treatment options, emphasizing 12-step support, anger management strategies, and cognitive behavioral therapy. Lantana Recovery adopts a personalized approach, ensuring high-quality care for both men and women. Clients can anticipate extensive support whether they opt for outpatient services or partial hospitalization, all within a compassionate and understanding setting. Opt for Lantana Recovery for evidence-based solutions and customized care on your path to recovery.

Las Vegas Paiute Tribe

Situated in Las Vegas, NV, the Las Vegas Paiute Tribe recovery facility extends outpatient support for substance use disorders, serving adults and seniors. This establishment delivers consistent outpatient care, employing proven methods like anger management, motivational interviewing, and cognitive behavioral therapy. Tailored programs are available for young people, adult males, and adult females, demonstrating a commitment to addressing varied requirements. The center ensures personalized support for all its male and female participants throughout their recovery process. The Las Vegas Paiute Tribe center is dedicated to providing excellent, all-encompassing rehabilitation services aimed at fostering lasting sobriety and emotional well-being.

Laurel Ridge Treatment Center

Laurel Ridge Treatment Center, situated in San Antonio, TX, provides extensive inpatient care for adults and children dealing with addiction and co-occurring mental health issues. Their hospital setting offers round-the-clock support, employing proven therapies like cognitive behavioral therapy and relapse prevention strategies. Specialized tracks are available for active military personnel, teenagers, and adult men, guaranteeing personalized treatment. The center emphasizes brief intervention and customized plans to deliver excellent care for individuals of all genders seeking recovery from substance abuse and mental health challenges.

Lawndale Christian Health Center

Lawndale Christian Health Center, located in Chicago, IL, delivers extensive outpatient services for adults dealing with substance use and serious co-occurring mental health conditions, as well as emotional challenges in children. The center focuses on specialized programs designed for individuals who have experienced trauma, incorporating methods such as anger management and cognitive behavioral therapy. It offers personalized outpatient treatments using methadone/buprenorphine or naltrexone, in addition to standard outpatient services. The facility is inclusive, serving adults and seniors of various genders, and prioritizing tailored, high-quality care for every individual. Lawndale Christian Health Center is recognized for its holistic treatment philosophy and dedication to assisting clients in their recovery journey.

Lawndale Christian Health Center

Lawndale Christian Health Center, located in Chicago, IL, specializes in a wide range of addiction treatment options tailored for adults and seniors. The facility offers programs such as intensive outpatient therapy and general outpatient support, along with targeted services for those facing both mental health challenges and substance abuse issues. The center employs various therapeutic methods, including anger management techniques, brief interventions, and cognitive behavioral therapy. Lawndale Christian Health Center serves individuals of all genders and provides outpatient options like methadone, buprenorphine, or naltrexone treatment. Committed to trauma-informed care, the center aims to deliver personalized, high-quality support to help clients successfully navigate their recovery journey.

Lamprey Healthcare

Situated in Raymond, NH, Lamprey Healthcare provides a wide array of substance abuse treatment options through its outpatient programs. This center is dedicated to supporting adult men, adult women, and individuals facing both mental health and substance use challenges. Emphasizing therapies such as anger management, brief interventions, and cognitive behavioral therapy, Lamprey Healthcare is designed for adults and young adults, regardless of gender. The facility offers tailored methadone, buprenorphine, or naltrexone programs, alongside standard outpatient services, ensuring that care is personalized to meet the unique needs of each client. Lamprey Healthcare is committed to offering high-quality, evidence-informed treatment to aid individuals in their recovery from addiction.

Lamprey Healthcare

Situated in Nashua, NH, Lamprey Healthcare specializes in providing targeted treatment for substance use to both adults and young adults. The center offers outpatient services such as methadone/buprenorphine or naltrexone therapy, along with standard outpatient programs and a range of strategies like anger management, brief interventions, and cognitive behavioral therapy. With an emphasis on delivering high-quality care, Lamprey Healthcare serves adult men and women, including those facing co-occurring mental health and substance use challenges. Its gender-specific initiatives and customized services foster a nurturing environment for individuals in pursuit of thorough and effective solutions for addiction recovery.

Lassen Indian Health Center

The Lassen Indian Health Center, situated in Susanville, CA, provides outpatient services for addiction and withdrawal management, designed for adults and older adults. They accommodate male and female patients, utilizing techniques like anger management, cognitive behavioral therapy, and brief interventions. Emphasizing personalized care plans, the center delivers excellent support for individuals battling substance dependence. Offering outpatient methadone, buprenorphine, or naltrexone treatments, the center is a well-rounded option for those starting their path to sobriety.

Lawndale Christian Health Center

Lawndale Christian Health Center, located in Chicago, IL, delivers outpatient services for individuals of all ages dealing with substance use challenges and concurrent serious mental health conditions. The center is adept at anger management, short-term interventions, and cognitive behavioral techniques, offering structured outpatient services complemented by medications like methadone, buprenorphine, or naltrexone. This program is designed for both men and women who have encountered traumatic experiences, providing essential support for adults and the elderly in search of effective rehabilitation solutions. Committed to addressing the intersection of substance use disorders and mental health issues, Lawndale Christian Health Center strives to offer thorough and impactful care for those requiring targeted treatment.

Launch Pad Wellness
Wilmington, NC

Launch Pad Wellness, situated in Wilmington, NC, specializes in extensive treatment for adults and young adults struggling with both substance use and concurrent serious mental health issues or emotional challenges. The center offers a variety of programs, including intensive outpatient and standard outpatient services, as well as treatments involving methadone/buprenorphine or naltrexone. Emphasizing personalized care, the facility incorporates methods such as 12-step facilitation, anger management, and brief interventions to aid in the recovery process. Serving both men and women, Launch Pad Wellness is recognized for its customized care approach and dedication to providing high-quality services. For those in search of effective addiction treatment within a nurturing atmosphere, this center is committed to guiding you towards sustained recovery.

Lakeview Center Inc

Situated in Century, FL, Lakeview Center Inc delivers a wide array of outpatient services focusing on detoxification and treatment for substance use disorders. The facility provides outpatient detox programs, methadone, buprenorphine, and naltrexone treatments, employing evidence-based methodologies such as brief interventions, cognitive behavioral therapy, and motivational incentives or contingency management. The center serves adult men and women, including those who have faced intimate partner or domestic violence. Catering to both adults and young adults, Lakeview Center Inc prioritizes personalized care, offering top-notch rehabilitation services designed to accommodate varying needs.

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Landmark Recovery of Western Michigan, located in Battle Creek, MI, provides a variety of evidence-supported treatment options for adults and young adults facing addiction challenges. This facility emphasizes detoxification, treatment for substance use, and handling co-occurring disorders. Offering a spectrum of services that includes intensive outpatient, long-term residential, and outpatient programs, the center emphasizes a tailored approach through methods such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. Additionally, there are specialized programs designed for active duty military and distinct groups of adult men and women, ensuring focused care. Catering to both genders, this center is dedicated to delivering effective and personalized rehabilitation solutions.

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Lawndale Christian Health Center, located in Chicago, IL, provides accessible outpatient care for individuals of all ages grappling with substance use and related mental health challenges. This center features distinct programs designed for those who have experienced trauma, offering support through anger management, short-term interventions, and cognitive behavioral therapy. Serving adults and older adults across the gender spectrum, the facility administers outpatient medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Emphasizing a commitment to high standards of care and personalized recovery journeys, Lawndale Christian Health Center stands as a reliable resource for comprehensive rehabilitation services within the Chicago community.

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Lawndale Christian Health Center, located in Chicago, IL, specializes in outpatient treatment for substance use disorders, as well as tailored services for those facing both substance use issues and significant mental health challenges. Their offerings include anger management sessions, brief intervention techniques, and cognitive behavioral therapy. The center accommodates regular outpatient services alongside programs that utilize methadone, buprenorphine, or naltrexone for treatment. With an emphasis on supporting individuals who have encountered trauma, the facility caters to adults and seniors across all genders. Lawndale Christian Health Center is committed to delivering exceptional, personalized care to assist clients in their recovery journey.

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Lawndale Christian Health Center, located in Chicago, IL, specializes in outpatient treatment for substance use among both adults and children facing concurrent mental health challenges. The center focuses on anger management, brief interventions, and cognitive behavioral therapy, offering personalized support for those who have experienced trauma. With services designed for adults and senior individuals, the facility provides outpatient options including methadone, buprenorphine, or naltrexone treatments alongside standard outpatient care. Catering to a diverse clientele of both men and women, Lawndale Christian Health Center is dedicated to delivering compassionate, high-quality care throughout the recovery process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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