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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Liberty Addiction Recovery Centers

Liberty Addiction Recovery Centers, located in West Jordan, UT, specializes in a wide range of treatment options for both adults and young adults dealing with substance use issues. The center offers a variety of programs, including intensive outpatient, outpatient services, and partial hospitalization options. It employs proven techniques such as cognitive behavioral therapy, 12-step facilitation, and motivational incentives to assist clients, particularly those facing both mental health and substance use challenges. With tailored programs for men and women, Liberty Addiction Recovery Centers is dedicated to providing exceptional care as individuals work toward their recovery goals.

Liberty Addiction Recovery Centers LLC

Liberty Addiction Recovery Centers LLC, located in Riverton, UT, is dedicated to providing tailored substance abuse treatment in a nurturing setting. The center features various residential programs, including options for 24-hour care and short-term stays, catering to both adults and young adults. Their treatment methods are grounded in research-based practices, employing strategies such as 12-step programs, brief interventions, and cognitive behavioral therapy. Special attention is given to those who have faced trauma, as well as individuals dealing with both mental health and substance use issues. Prioritizing personalized treatment, Liberty Addiction Recovery Centers LLC also offers gender-specific services for men and women. Experience thorough support and quality treatment at this center.

Liberty House Recovery

Situated in Redlands, CA, Liberty House Recovery delivers extensive rehabilitation programs for both adults and young adults facing challenges with substance use and concurrent mental health issues. The center features hospital-based inpatient detoxification and treatment services, with tailored programs designed for active duty military personnel, as well as adult men and women. Emphasizing 12-step support, anger management techniques, and brief intervention strategies, Liberty House Recovery provides specialized care for men and women in search of personalized treatment. Its dedication to meeting the distinct requirements of each individual distinguishes it as a reliable option for those on their path to recovery.

Liberty House Recovery Center

Situated in Fenton, MI, Liberty House Recovery Center delivers extensive addiction treatment services for both adults and young adults. The center features residential detox programs, round-the-clock residential support, and short-term care options. By employing 12-step methodologies, anger management techniques, and cognitive behavioral therapy, this facility addresses the needs of individuals dealing with concurrent mental health issues and substance use disorders. With specialized programs designed for male and female patients, Liberty House Recovery Center prioritizes high-quality care in a nurturing setting. For those in search of effective interventions for substance use and dual diagnoses, this center is committed to facilitating long-term recovery.

Liberty Manor
Rochester, NY

In Rochester, NY, Liberty Manor provides extensive long-term residential care for women facing addiction and co-occurring mental health challenges. The center is particularly equipped to assist survivors of domestic violence, intimate partner violence, and sexual abuse, offering a secure and nurturing atmosphere. Employing proven therapeutic methods like 12-step facilitation, anger management, and brief intervention, Liberty Manor champions complete healing and sustained recovery. Designed for adults of all ages, from young adults to seniors, the facility delivers individualized attention and support to aid each resident in achieving sobriety and improved mental health.

Life Center of Connecticut Inc

Situated in Hartford, CT, the Life Center of Connecticut Inc delivers comprehensive rehabilitation services aimed at adult males facing challenges related to substance use disorders alongside significant mental health concerns. The facility offers a variety of treatment options, including long-term, short-term, and round-the-clock residential care. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, the center customizes its programs to support individuals who have experienced intimate partner violence and those from active duty military backgrounds. Catering to adult men, including seniors and young adults, Life Center of Connecticut Inc is dedicated to providing high-quality treatment in a nurturing environment to facilitate recovery and personal growth.

Life Line Services LLC

Located in Greenville, SC, Life Line Services LLC provides an extensive array of outpatient treatment options for adults and young adults facing issues related to substance abuse and concurrent mental health disorders. The center is dedicated to detoxification, treatment for substance use, and addressing co-occurring conditions, offering services like outpatient detox, as well as methadone and buprenorphine treatments, including naltrexone. Committed to personalized care, Life Line Services LLC utilizes evidence-based methodologies, such as 12-step programs, anger management techniques, and brief interventions. This facility serves both men and women, focusing on high-quality care and customized assistance to support individuals in achieving long-term recovery.

Life Recovery Center

Life Recovery Center, situated in Bronx, NY, provides extensive inpatient hospital detoxification and substance use treatment. This establishment is dedicated to personalized care, offering specific programs for adults and young adults. With a holistic strategy, the center supports both male and female individuals pursuing effective addiction recovery. Life Recovery Center distinguishes itself through its constant, 24-hour inpatient hospital services, guaranteeing continuous care and assistance for individuals in their recovery process. For those seeking personalized and focused addiction treatment, this center offers a secure and encouraging setting to commence the transition to improved well-being.

Liberty Health Services

Liberty Health Services, based in Derry, NH, provides an extensive range of addiction recovery programs for both adults and young adults. This facility emphasizes detoxification and offers inpatient care with round-the-clock assistance. Their treatment methodologies encompass 12-step facilitation, anger management techniques, and brief interventions, all customized to meet each individual’s requirements. A distinguishing feature of this center is its dedication to personalized care, with specialized programs crafted for each participant. Liberty Health Services welcomes both men and women, creating a secure and nurturing atmosphere for those on their journey to recovery.

Life Challenge Mental Health Services

Situated in Detroit, MI, Life Challenge Mental Health Services presents an extensive variety of rehabilitation options. This center specializes in long-term residential care, outpatient services, and structured outpatient programs designed for both adults and young adults. Emphasizing treatment for substance use disorders, transitional living, and co-occurring mental health and substance use disorders, the facility employs methods including 12-step support, anger management techniques, and brief intervention strategies. There are specialized programs available for adult men, adult women, and individuals affected by intimate partner violence. Life Challenge Mental Health Services is committed to providing high-quality support for those on the path to recovery from addiction and mental health issues.

Libertae Inc
Bensalem, PA

Libertae Inc, located in Bensalem, PA, specializes in rehabilitation services designed specifically for adult women dealing with substance use issues. The center offers various treatment options, including intensive outpatient care, long-term residential programs, and outpatient services that integrate techniques such as 12-step approaches, cognitive behavioral therapy, and anger management. Libertae Inc creates a safe and nurturing space for women who have faced challenges like intimate partner violence, domestic abuse, and sexual trauma. This center caters to seniors, young adults, and adults, ensuring high-quality care and distinctive programs, making it an important asset for individuals seeking thorough rehabilitation support.

Life Change Center

Situated in Sparks, NV, the Life Change Center provides an extensive outpatient program focused on substance use recovery for both adults and young adults. This center is adept at addressing dual diagnosis, treating individuals with overlapping substance use challenges and severe mental health issues in adults or significant emotional disturbances in minors. The treatment approach integrates 12-step programs, anger management techniques, and brief interventions to foster recovery. With specialized offerings for men, women, and those with dual diagnoses, the facility emphasizes personalized care for every individual. They also deliver outpatient treatment options using methadone, buprenorphine, or naltrexone, alongside standard outpatient services, ensuring exceptional care for clients pursuing meaningful life transformations.

Life Net Services LLC
Fayetteville, NC

Life Net Services LLC in Fayetteville, NC, is a dedicated facility providing thorough substance use disorder treatment for adults and children experiencing co-occurring mental health conditions. Their offerings include intensive outpatient and standard outpatient services, incorporating medication-assisted treatment like methadone and buprenorphine. The center emphasizes therapeutic approaches such as cognitive behavioral therapy, anger management, and brief intervention strategies to address the varied requirements of their clientele. Specialized support is extended to individuals managing co-occurring pain disorders, those navigating the criminal justice system, and forensic clients. Life Net Services LLC is committed to delivering high-quality care and fostering a supportive environment for adults, adolescents, and young adults across all genders on their journey to recovery and well-being.

Life Net Services LLC
Fayetteville, NC

Life Net Services LLC, located in Fayetteville, NC, delivers complete addiction recovery care for adults and youth facing concurrent severe mental health conditions. This establishment features intensive and standard outpatient services, incorporating medication-assisted treatments such as methadone/buprenorphine and naltrexone. Employing therapeutic modalities like anger management and cognitive behavioral therapy, the center serves both male and female individuals. Tailored programs exist for teenagers and those involved with the legal or forensic system. Emphasizing high-quality support and diverse therapeutic avenues, Life Net Services LLC stands as a crucial provider of effective recovery solutions in the Fayetteville region.

Life Vessel Treatment and
Mission Viejo, CA

Life Vessel Treatment and, situated in Mission Viejo, CA, delivers thorough recovery programs for adults and young adults facing addiction and accompanying mental health challenges. This establishment offers extended stay residential care, inpatient detox, and round-the-clock residential assistance. Featuring tailored programs for active military personnel, adult males, and adult females, Life Vessel Treatment and addresses varied requirements. Employing methods like 12-step encouragement, emotional regulation training, and short-term counseling, the center guarantees personalized support. Assisting both male and female individuals, this facility is dedicated to providing excellent, impactful treatment for sustained wellness.

LifeSkills Inc
Bowling Green, KY

LifeSkills Inc, located in Bowling Green, KY, provides exceptional residential treatment for substance use issues. The center emphasizes 12-step programs, anger management strategies, and brief intervention methods. Designed for adult men, the facility also supports individuals affected by intimate partner violence, domestic violence, and sexual abuse. LifeSkills Inc focuses on offering personalized care for adults, seniors, and young adults, ensuring that male clients receive the attention they need. The center's short-term and 24-hour residential treatment options deliver thorough assistance for those pursuing recovery. With a dedication to high-quality care, LifeSkills Inc is recognized as a reliable resource for individuals facing substance use difficulties.

Liberation Programs Inc

Liberation Programs Inc, situated in Bridgeport, CT, delivers thorough substance abuse care for adults of all genders, including individuals with a history of sexual trauma. They offer a range of services such as intensive outpatient, standard outpatient, and medication-assisted treatment (MAT) utilizing methadone, buprenorphine, or naltrexone. The center emphasizes therapeutic interventions including anger management, cognitive behavioral therapy (CBT), and motivational incentives, serving both adults and young adults needing specialized support. Their individualized and gender-informed treatment plans are designed for optimal recovery outcomes. Liberation Programs Inc is recognized for its dedication to providing high-quality, supportive services to clients on their path to lasting sobriety.

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Liberation Programs Inc., situated in Stamford, CT, provides extensive residential rehabilitation for adults grappling with substance abuse and co-occurring severe mental health conditions, as well as children experiencing significant emotional distress. Their therapeutic framework incorporates the principles of 12-step recovery, anger management techniques, and brief intervention strategies. This institution is dedicated to serving adult men, individuals diagnosed with HIV or AIDS, and those concurrently managing mental health and substance use disorders. Their services extend to adults, older adults, and young adults, ensuring a nurturing setting designed for male individuals pursuing thorough recovery and personal growth.

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Liberty, NY

Liberty Clinic, situated in Liberty, NY, delivers complete outpatient recovery programs for individuals of all ages grappling with substance use issues and concurrent mental health concerns. The facility features tailored care plans for active military members, teenagers, and adult males. Emphasizing 12-step support, emotional regulation strategies, and short-term counseling, Liberty Clinic customizes its offerings to address the unique requirements of every patient. Providing outpatient medication-assisted treatment with methadone, buprenorphine, and naltrexone, the clinic adopts a comprehensive approach to healing. Catering to both genders, Liberty Clinic is dedicated to delivering excellent care to foster enduring sobriety and psychological well-being.

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Situated in Tutwiler, MS, Life Help/Region 6 CMC provides extensive long-term residential rehabilitation for adult women facing challenges with substance abuse and concurrent mental health disorders. Emphasizing 12-step programs and anger management strategies, this center delivers tailored support for those who have been victims of intimate partner violence. The facility also offers residential detox services and short-term intervention programs suitable for adults, seniors, and young adults. Life Help/Region 6 CMC is distinguished by its dedication to high-quality care, making it a preferred option for women in search of a nurturing space for their recovery journey.

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Santa Fe, NM

Situated in Santa Fe, NM, Life Link is dedicated to providing a wide range of rehabilitation services for both adults and children. This center focuses on treating substance use issues and concurrent conditions such as significant mental health disorders or emotional challenges. Emphasizing intensive outpatient programs and tailored treatment plans, Life Link employs strategies like cognitive behavioral therapy and community reinforcement to facilitate recovery. The center features distinct programs designed for adult men, adult women, and individuals with a history of trauma. By accommodating clients of all genders, Life Link is committed to delivering effective support for those on the path to overcoming addiction and mental health difficulties.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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