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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Longbranch Recovery and Wellness

Nestled in Metairie, LA, Longbranch Recovery and Wellness is dedicated to assisting those on their journey toward overcoming substance use disorders. Their holistic approach encompasses detoxification services, comprehensive substance use treatment, and tailored support for individuals of all ages facing the complexities of dual diagnoses. Longbranch Recovery and Wellness provides a spectrum of outpatient care, including intensive programs, general outpatient services, and outpatient detoxification. Utilizing proven therapeutic modalities like 12-step facilitation, anger management, and cognitive behavioral therapy, they foster healing. Dedicated programs are available for individuals with co-occurring mental health and substance use conditions, offering personalized support for adults and young adults, irrespective of gender. Discover effective care and dedicated assistance at Longbranch Recovery and Wellness.

Loretto Hospital
Chicago, IL

Situated in Chicago, IL, Loretto Hospital provides a wide range of rehabilitation services aimed at adults and young adults dealing with substance use disorders, alongside co-occurring mental health issues. This establishment focuses on hospital inpatient detoxification and offers treatment with round-the-clock supervision, employing methods like brief intervention, relapse prevention, and counseling for substance use disorders. With customized programs for adult men, women, and those who have faced intimate partner or domestic violence, Loretto Hospital is committed to delivering individualized support for every patient. Their specialized care for all genders among adults and young adults highlights their dedication to comprehensive healing and recovery.

Lott Behavioral Health

At Lott Behavioral Health in Lisle, IL, we provide complete outpatient care for those striving for sobriety from addiction and dual diagnoses. Our programs are tailored for adults managing significant mental health challenges and children with emotional concerns. Emphasizing a personal approach, Lott Behavioral Health employs proven methods like CBT and 12-step guidance. We offer outpatient detox and MAT using methadone, buprenorphine, or naltrexone, serving all genders and ages. Discover excellent, customized support at Lott Behavioral Health.

Lotus Recovery Centers

Lotus Recovery Centers, situated in Comfort, WV, provides a thorough suite of addiction rehabilitation options. Their expertise lies in aiding individuals through the detox process and managing substance dependencies, offering extended stay residences, detox accommodations, and round-the-clock residential care. Employing strategies like 12-step support, emotional regulation techniques, and focused short-term counseling, the center serves adult men and women, including those in active military service. With treatment plans designed for both older adults and younger individuals, Lotus Recovery Centers guarantees individualized support for everyone. Whether you are looking for recovery for yourself or assisting someone else, you can anticipate top-tier, gender-focused services at this respected recovery establishment.

Lotus Recovery Centers of

Lotus Recovery Centers located in Wilmington, DE provides an extensive array of treatments for substance use and tailored programs aimed at adults and young adults dealing with co-occurring mental health issues. This center features intensive outpatient care, outpatient services, and options for methadone, buprenorphine, or naltrexone treatments. Emphasizing 12-step assistance, anger management, and brief intervention strategies, the facility serves both men and women, including those with trauma histories. With a commitment to high-quality care, Lotus Recovery Centers is dedicated to personalized treatment plans that foster recovery and promote overall wellness.

Louis Stokes VA Medical

Located in Canton, OH, Louis Stokes VA Medical delivers extensive treatment options for substance use disorders, catering to both adults and young adults grappling with significant mental health challenges or emotional issues. Their programs, which include both intensive and regular outpatient services, utilize proven methods such as 12-step guidance, anger management techniques, and short-term interventions. This center is dedicated to providing focused support to both men and women, as well as those who have suffered from domestic or intimate partner violence. Emphasizing gender-specific care, the facility personalizes its services to meet the unique needs of each patient. Individuals can also receive outpatient treatment options involving methadone, buprenorphine, or naltrexone. The center's dedication to high-quality care positions it as an essential option for individuals in need of effective rehabilitation.

Lowell Community Health Center Inc

Situated in Lowell, MA, Lowell Community Health Center Inc delivers extensive outpatient services for adults confronting substance use challenges alongside mental health issues. The center features tailored programs aimed at adolescents as well as male and female adults, employing verified methods like cognitive behavioral therapy, anger management, and short-term interventions. Committed to high-quality treatment, this facility administers outpatient options including methadone, buprenorphine, and naltrexone for adults and seniors of all genders. For those in need of individualized and effective support in their recovery journey, Lowell Community Health Center Inc is dedicated to guiding individuals toward healing and wellness.

Lowell Comprehensive Treatment Center

The Lowell Comprehensive Treatment Center, situated in Lowell, MA, delivers tailored outpatient care for individuals grappling with substance use issues, including both adults and younger populations. This center specializes in administering methadone, buprenorphine, or naltrexone treatment and employs various techniques such as 12-step programs, anger management strategies, and brief interventions. It features distinct offerings designed for adult men and women, as well as those affected by intimate partner or domestic violence. Emphasizing personalized treatment, the center is dedicated to providing compassionate and skilled care to all clients, making the Lowell Comprehensive Treatment Center a reliable option for effective addiction recovery solutions.

Luke Air Force Base
Glendale Luke AFB, AZ

Luke Air Force Base in Glendale, Arizona, features outpatient programs aimed at addressing substance use for both adults and young adults. The facility emphasizes regular outpatient care through clinically-supported methods, including brief interventions, cognitive behavioral strategies, and motivational interviewing techniques. While primarily serving active duty military members, it accommodates clients of all genders, ensuring inclusive support. The center is committed to providing personalized treatment plans that empower individuals in their recovery process.

Lukner Medical Clinic PLLC

Situated in Pampa, TX, Lukner Medical Clinic PLLC provides extensive restorative care. The clinic focuses on detoxifying individuals, treating dependency issues, and addressing co-occurring conditions for both younger and older patients. Through rigorous outpatient, standard outpatient, and detox programs, Lukner Medical Clinic PLLC delivers customized support utilizing methods like rage control, swift intervention, and cognitive behavioral techniques. This establishment serves active military personnel, teenagers, adult males, and adult and elderly individuals. Both male and female patients benefit from treatment plans created specifically for them, guaranteeing excellent support designed for each person's unique requirements.

Lumiere Healing Center
West Chester, OH

In West Chester, OH, Lumiere Healing Center is dedicated to providing extensive care for substance use disorders. This institution offers inpatient medical detoxification and treatment, alongside supportive housing for individuals requiring it. Lumiere Healing Center features tailored programs for active military personnel, adult males, and adult females, accommodating a broad spectrum of clients. Their treatment methods incorporate 12-step program guidance, strategies for managing anger, and short-term interventions to meet diverse requirements. Catering to adults and young adults of all genders, the center prioritizes individualized attention and assistance throughout the recovery journey.

Luminis Health Pathways

Situated in Annapolis, MD, Luminis Health Pathways delivers comprehensive rehabilitation services for detoxification, substance dependency, and co-occurring mental health disorders in adults, as well as emotional issues in children. Prioritizing high-quality treatment, the center offers hospital inpatient detox services, therapeutic interventions, and round-the-clock care through various methods, including 12-step programs, anger management, and short-term interventions. Customized programs are available for adult men and those who have faced trauma, including situations of intimate partner violence or domestic abuse. This facility is dedicated to providing tailored care and assistance to individuals of all ages and genders who are on the journey to recovery from addiction and mental health difficulties.

Lower Shore Clinic Inc

Lower Shore Clinic Inc, located in Cambridge, MD, provides outpatient services for adults and young adults dealing with substance use and accompanying mental health challenges. The center focuses on tailored programs that effectively target both addiction and significant mental health issues. Treatment methods include outpatient support featuring medications like methadone, buprenorphine, or naltrexone. Lower Shore Clinic Inc employs techniques such as 12-step facilitation, anger management, and brief interventions to assist clients in their recovery processes. Committed to delivering high-quality care, the facility serves both men and women seeking thorough and personalized treatment plans for substance use disorders coupled with mental health conditions.

Lower Shore Clinic Inc

Lower Shore Clinic Inc, situated in Salisbury, MD, provides extensive outpatient care for those pursuing substance use treatment and healing. This establishment focuses on adult and child services, including detoxification and integrated mental health and substance use care. They emphasize outpatient detox and medication-assisted treatment with methadone or buprenorphine, utilizing proven methods like cognitive behavioral therapy and anger management. Lower Shore Clinic Inc also accommodates individuals with trauma or sexual abuse backgrounds, fostering a secure and encouraging setting for recovery. Serving adults and young adults across all genders, the clinic is dedicated to offering superior treatment to aid clients in their recovery path.

Lummi Counseling Services

Lummi Counseling Services in Bellingham, WA, delivers complete care for addiction, concentrating on detox and substance abuse support. This location provides intensive outpatient treatment, standard outpatient programs, and outpatient detox services to suit diverse requirements. Employing proven methods such as 12-step guidance, brief intervention, and cognitive behavioral therapy, the center customizes treatment plans for each person. Specialized programs are available for young people, adult males, and adult females. Catering to both adults and younger individuals, Lummi Counseling Services ensures individualized support for all genders. Dedicated to high-quality and successful recovery, this center is a reliable choice for individuals pursuing expert addiction treatment.

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Situated in Sterling, VA, Loudoun County Mental Health Center specializes in outpatient services for both substance use disorders and concurrent mental health issues affecting adults and children. The center emphasizes a range of therapeutic approaches, including 12-step facilitation, cognitive behavioral therapy, and contingency management, all designed to provide personalized treatment solutions. It features distinct programs tailored for active duty military personnel, adolescents, and adult males to ensure thorough support. Catering to adults and seniors of all genders, the center is committed to offering high-quality, evidence-based treatment aimed at fostering enduring recovery and overall well-being. For those in search of effective addiction recovery services within a nurturing setting, Loudoun County Mental Health Center is focused on helping you reach your objectives.

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In Leesburg, VA, the Loudoun County Mental Health Center provides extensive outpatient care for individuals of all ages dealing with substance use issues and co-occurring mental health conditions. Employing proven methods such as 12-step facilitation, cognitive behavioral therapy, and motivational incentives, the center serves a diverse clientele including military personnel, teenagers, adult men, and older adults. The center is dedicated to delivering high-quality treatment with specific programs designed for male and female patients. For those in need of addiction recovery or mental health assistance, the Loudoun County Mental Health Center offers personalized treatment strategies and a team of skilled professionals.

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Situated in Bryn Mawr, Pennsylvania, Lower Merion Counseling and offers extensive outpatient treatment for substance use disorders, catering to both adults and children facing concurrent mental health challenges. The center features targeted programs designed specifically for adult men, women, and individuals who have undergone traumatic experiences. Treatment methodologies encompass anger management, brief interventions, and cognitive behavioral therapy. Providing tailored services for adults and seniors of all genders, this center ensures high-quality care through outpatient options, including methadone/buprenorphine or naltrexone treatments, in addition to standard outpatient programs. Consider Lower Merion Counseling and for individualized and effective rehabilitation solutions.

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The Luminosity Bakari Program, situated in Brockton, MA, provides outpatient substance use disorder treatment and detoxification for adults managing co-occurring mental health conditions. The program excels in anger management, cognitive behavioral therapy, and brief intervention techniques. Specialized tracks are offered for active military personnel, teenagers, and adult men. Primarily an outpatient facility, it serves individuals of all ages and genders, including older adults. The Luminosity Bakari Program delivers effective addiction treatment within a nurturing setting, presenting a strong option for individuals requiring thorough and personalized support.

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Lutheran Community Services NW, located in Portland, OR, provides comprehensive outpatient services for adults struggling with substance use disorders, particularly those with co-occurring serious mental health conditions or children experiencing emotional disturbances. Their therapeutic approaches incorporate 12-step facilitation, brief intervention strategies, and cognitive behavioral therapy. This establishment offers distinct programs designed for adult men, women, and individuals who have endured intimate partner violence. Catering to adult and young adult populations of both genders, Lutheran Community Services NW is dedicated to delivering exceptional, individualized care.

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Lutheran Family Services of Nebraska, located in Fremont, NE, provides targeted substance use recovery programs for both adults and young adults who are also battling mental health challenges. Their extensive treatment offerings include intensive outpatient and outpatient services, utilizing proven methods like cognitive behavioral therapy and motivational incentives. Emphasizing personalized care, this center develops customized treatment strategies for male and female clients alike. Individuals enjoy a nurturing atmosphere that allows them to confront their specific needs in a constructive manner. Lutheran Family Services of Nebraska is dedicated to offering exceptional rehabilitation support to assist individuals in attaining enduring recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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