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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Luxe Recovery
Los Angeles, CA

Nestled in Los Angeles, CA, Luxe Recovery delivers thorough substance abuse recovery for adults and adolescents. This institution features extended residential stays, encompassing detox and round-the-clock assistance. Luxe Recovery focuses on addressing dual diagnoses of addiction and significant mental health conditions, supporting those who have experienced trauma or sexual abuse. Offering distinct programs for men and women, Luxe Recovery employs proven methods such as 12-step support and emotional regulation techniques to ensure excellent treatment. From short-term solutions to in-depth residential stays, individuals will receive tailored care at Luxe Recovery.

Luxe Treatment Center LLC

Nestled in Las Vegas, NV, Luxe Treatment Center LLC focuses on delivering in-depth addiction recovery solutions for both adults and younger individuals. The center features long-term residential services, detoxification support, and continuous care available around the clock for those facing substance use challenges alongside significant mental health issues. Luxe Treatment Center LLC employs methods such as 12-step programs, anger management strategies, and short intervention techniques. Its programs cater specifically to men, women, and clients who have witnessed trauma, ensuring personalized treatment plans that address a wide range of requirements. Committed to fostering a nurturing atmosphere for clients of all genders, Luxe Treatment Center LLC aims to provide effective, research-supported therapies that facilitate sustainable recovery.

Lynn Community Health Center Inc

Situated in Lynn, MA, Lynn Community Health Center Inc provides an extensive range of substance use treatment for both adults and children facing co-existing mental health issues. The center offers outpatient services, such as methadone and buprenorphine therapies, as well as cognitive behavioral therapy. Emphasizing short-term interventions and motivational rewards, the facility serves adult males, trauma survivors, and those with co-occurring conditions. Catering to adults and seniors across all genders, this center guarantees high-quality care through customized programs aimed at meeting the specific needs of every individual.

MARR
Atlanta, GA

MARR, located in Atlanta, GA, is dedicated to providing extensive addiction recovery care for adult males in need of substance abuse support. The center features transitional living, halfway house, and sober living arrangements within a nurturing atmosphere. Treatment is available in various formats, including intensive outpatient, extended residential stays, and outpatient services. MARR's expertise lies in its application of 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Specialized offerings are designed for adult men, particularly those who have faced intimate partner violence or sexual trauma. Catering to a broad age range from young adults to seniors, MARR prioritizes delivering exceptional care customized for the unique journey of men pursuing sobriety.

MARR Right Side Up

MARR Right Side Up, situated in Atlanta, GA, is a leading treatment center dedicated to aiding adult women in overcoming substance use disorders. This facility features both long-term residential and round-the-clock residential options, cultivating a nurturing atmosphere for individuals who have endured intimate partner violence, domestic abuse, or sexual trauma. By integrating 12-step principles, anger management techniques, and cognitive behavioral therapy, MARR Right Side Up serves adults, seniors, and young adults in pursuit of thorough rehabilitation. The center's tailored programs and gender-exclusive methodology guarantee personalized treatment strategies and superior care for those embarking on a journey of addiction recovery.

MAT Texas
Grand Prairie, TX

MAT Texas in Grand Prairie, TX, delivers outpatient substance use treatment and detox services for adults and young adults. They emphasize personalized care through brief interventions, cognitive behavioral therapy, and motivational incentives to aid recovery. MAT Texas specializes in outpatient methadone, buprenorphine, or naltrexone treatment for both male and female clients needing thorough addiction support. Their use of evidence-based methods and tailored programs guarantees excellent care for individuals aiming to conquer substance use issues.

MAT Care Clinics

Located in Nashua, NH, MAT Care Clinics specializes in outpatient treatment for adults struggling with substance use issues alongside significant mental health challenges and also addresses emotional issues in children. The center offers treatment options such as methadone, buprenorphine, or naltrexone, in addition to standard outpatient services. Tailored programs are available for active military members as well as adult males and females. The center provides a range of services including 12-step support, anger management classes, and brief intervention strategies. MAT Care Clinics is committed to delivering effective care to adults and young adults of all genders who are looking to overcome addiction and mental health difficulties.

MAHEC Center for Psychiatry and

The MAHEC Center for Psychiatry and in Asheville, NC provides targeted care for adults struggling with addiction and co-occurring mental health challenges, as well as addressing emotional difficulties in young people. Their offerings encompass intensive outpatient programs, standard outpatient services, and medication-supported therapies, ensuring diverse approaches to support personal recovery journeys. Employing techniques like anger management, brief intervention, and cognitive behavioral therapy, the center customizes treatment strategies for every individual. This institution distinguishes itself through its commitment to personalized support, catering to adults and older adults of any gender. For individuals in search of thorough and tailored recovery programs, the MAHEC Center for Psychiatry and is committed to delivering exceptional treatment.

MATClinics
Dundalk, MD

MATClinics, located in Dundalk, MD, provides comprehensive outpatient and intensive outpatient programs aimed at assisting both adults and young adults dealing with substance use issues and concurrent mental health disorders. The center employs proven methods such as cognitive behavioral therapy and short-term interventions to cater to its diverse clientele, including active military members and both male and female adults. Additionally, there are customized options for outpatient treatments using methadone, buprenorphine, or naltrexone. Emphasizing personalized and high-quality care, MATClinics fosters a nurturing atmosphere for clients pursuing recovery from substance use and mental health difficulties.

MATClinics
Laurel, MD

MATClinics, located in Laurel, MD, provides a variety of treatment options for adults and young adults facing substance abuse issues alongside mental health challenges. The center features intensive outpatient programs, outpatient services, and targeted treatments with methadone, buprenorphine, or naltrexone. Utilizing techniques such as cognitive behavioral therapy and motivational incentives, MATClinics prioritizes personalized care. The center also has specialized programs designed for active military members, as well as distinct support for adult men and women. By offering services for both genders, this facility takes a holistic approach to addiction recovery, serving as a crucial support system for individuals on their path to healing.

MARR
Lawrenceville, GA

MARR in Lawrenceville, GA, provides extensive recovery support specifically designed for women addressing substance use disorders. Their offerings include intensive outpatient care, extended residential stays, and outpatient options that integrate proven therapeutic methods like 12-step facilitation, anger management, and cognitive behavioral therapy. Specialized services are available for adult women, as well as those impacted by intimate partner violence, domestic abuse, and sexual assault. The center is equipped to support adults, older adults, and young adults, fostering a secure atmosphere for women pursuing sobriety. MARR prioritizes personalized care and a secure, encouraging setting for women committed to their recovery path.

MATClinics
Annapolis, MD

MATClinics in Annapolis, MD, provides comprehensive, evidence-supported therapies for addiction and accompanying mental health challenges. Services include robust outpatient programming, standard outpatient care, and medication-assisted recovery with methadone, buprenorphine, or naltrexone. Their approach incorporates proven therapeutic methods like CBT, brief intervention, and contingency management. MATClinics serves diverse groups, including active military, adults of all genders, and young adults. Prioritizing excellent care, this center is committed to empowering individuals as they pursue sobriety.

Lutheran Family Services of Nebraska

Lutheran Family Services of Nebraska, located in Lincoln, NE, provides targeted substance abuse treatment for adults and young adults experiencing co-occurring severe mental health conditions or emotional challenges. Their structured programs, including intensive outpatient services, general outpatient support, and medication-assisted treatment with methadone, buprenorphine, or naltrexone, offer customized interventions such as anger management, brief intervention strategies, and cognitive behavioral therapy. The center emphasizes a personalized approach, welcoming both male and female individuals in their pursuit of effective rehabilitation. For those requiring thorough and individualized addiction care, this facility offers a nurturing setting for recovery and well-being.

MAAC Project
San Diego, CA

The MAAC Project in San Diego, CA, provides tailored substance abuse recovery services for adult women impacted by domestic violence, sexual assault, and intimate partner abuse. This center offers various residential treatment durations, including extended stays, shorter programs, and immediate 24-hour care. Their approach integrates anger management techniques, proactive brief interventions, and evidence-based cognitive behavioral therapy. Serving a diverse age range from young adults to seniors, the MAAC Project emphasizes gender-specific support. They are recognized for their thorough programs designed to address the distinct challenges faced by women in their healing process, delivering exceptional support and quality care.

MAAC Project
Chula Vista, CA

MAAC Project in Chula Vista, CA, provides targeted substance abuse rehabilitation for adult males. The center features diverse residential options, including extended stays, shorter durations, and round-the-clock care. Their treatment methodologies incorporate anger management, brief intervention strategies, and cognitive behavioral therapy, all personalized for each client's requirements. Distinctive programs are available for adult men who have endured intimate partner violence, domestic abuse, or sexual trauma. Serving a broad age spectrum from young adults to seniors, MAAC Project prioritizes high-quality care with a specific emphasis on male individuals. MAAC Project is a reputable provider for those in search of thorough and successful recovery services.

MATClinics
Towson, MD

MATClinics in Towson, Maryland, provides a thorough approach to substance use rehabilitation for both adults and young adults grappling with severe mental health conditions or emotional issues. The center offers a variety of treatment options, including intensive outpatient programs, standard outpatient care, and specialized programs utilizing methadone, buprenorphine, or naltrexone. By incorporating techniques such as brief intervention, cognitive behavioral therapy, and contingency management with motivational incentives, MATClinics personalizes its treatment plans to meet the distinct needs of each patient. Focused programs for active military personnel, adult men, and adult women ensure that care is customized to address gender-specific requirements. Patients can anticipate high-quality, research-supported treatment within a nurturing atmosphere designed to foster long-term recovery.

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Situated in Eau Claire, WI, Lutheran Social Services of Wisconsin delivers exceptional addiction recovery services within a nurturing atmosphere. This center focuses on treating substance use disorders and offers various options, including transitional housing, halfway houses, and sober living arrangements for women, seniors, and young adults. With both short-term and long-term residential programs available, the facility ensures customized care that meets the unique needs of each client. The treatment methods include 12-step programs, anger management, and brief interventions, specifically designed for individuals who have faced intimate partner violence, domestic violence, or sexual abuse. This center is renowned for its dedication to high-quality, individualized care in a compassionate environment.

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M and M Behav Health Solutions LLC, located in Glen Burnie, MD, specializes in rehabilitation services for individuals dealing with substance use issues and accompanying mental health challenges for both adults and children. The facility offers a range of services, including intensive outpatient programs, outpatient support, and medication-assisted treatment with options such as methadone, buprenorphine, or naltrexone. By employing evidence-based methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the center customizes treatment plans to suit the unique needs of each patient. It features programs specifically aimed at adult men, women, and those who have faced intimate partner violence, ensuring it serves a wide array of communities. The center is dedicated to providing effective care and assistance to individuals of all genders seeking to recover from addiction and mental health issues.

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M and M Behavioral Health Solution, located in Glen Burnie, MD, specializes in treating substance use disorders among adults and children who also face serious mental health challenges. The facility offers a range of treatment modalities, including intensive outpatient programs, outpatient care, and options involving methadone, buprenorphine, or naltrexone. Adopting evidence-based practices such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing, M and M crafts personalized treatment strategies to address the unique needs of each client. The center also features tailored programs for adult men and women, as well as individuals who have been victims of intimate partner violence. Focused on providing high-quality, holistic care, it is dedicated to helping both adults and young adults achieve lasting recovery.

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MBI Health Services Inc, situated in Los Angeles, CA, provides a complete spectrum of recovery services for adults and adolescents facing challenges with addiction and co-occurring mental health conditions. Emphasizing intensive outpatient care and day treatment options, this center delivers expert support through modalities like 12-step integration, emotional regulation strategies, and concise therapeutic interventions. Distinctive programs are designed for adult men and women, as well as individuals with a history of sexual trauma. Dedicated to personalized attention, MBI Health Services Inc cultivates a nurturing atmosphere conducive to healing. All clients, regardless of gender, receive exceptional and customized treatment to aid their path to sustained abstinence and psychological well-being.

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MBI Health Services LLC, located in Washington, DC, delivers extensive care for individuals struggling with substance use disorders, particularly those with co-occurring serious mental health conditions or emotional challenges. Their program offerings include intensive outpatient services, standard outpatient care, and day treatment programs. The center employs evidence-based strategies such as 12-step facilitation, anger management techniques, and brief intervention methods. MBI Health Services LLC is equipped to support adult men, women, and those impacted by intimate partner or domestic violence. With a dedication to all adults and seniors regardless of gender, MBI Health Services LLC prioritizes excellent care and tailored recovery journeys.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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