NWVCIL Logo
Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6655 results

MacNeal Hospital

MacNeal Hospital in Berwyn, IL is dedicated to providing extensive addiction treatment for individuals, both adults and young adults, who are dealing with substance use disorders and overlapping mental health issues. The center offers a range of services including hospital-based inpatient detox, intensive outpatient programs, and round-the-clock hospital inpatient care. Employing methods like 12-step facilitation, cognitive behavioral therapy, and brief intervention, the facility customizes treatment plans to suit each person's unique requirements. Their specialized programs are designed for individuals with co-occurring disorders, guaranteeing comprehensive care. Prioritizing high standards and individualized treatment, MacNeal Hospital accepts both male and female patients, fostering a nurturing atmosphere for healing and recovery.

Madrona Recovery
Portland, OR

Madrona Recovery, located in Portland, OR, delivers an extensive array of services to those pursuing recovery from addiction. This center specializes in care for detoxification, treatment of substance use disorders, and co-occurring mental health issues for both adults and minors. It features residential detox options, around-the-clock residential care, as well as short-stay programs. Emphasizing 12-step approaches, anger management, and quick intervention techniques, Madrona Recovery personalizes treatment strategies to fit each individual's circumstances. The center stands out with its distinct offerings for teenagers, individuals who have experienced intimate partner violence, domestic abuse, and sexual trauma. Madrona Recovery admits clients of all genders, including children and teens, ensuring inclusive and quality support for every age group.

Magnolia Medical Group

Magnolia Medical Group, located in Denver, CO, delivers focused outpatient care for adults grappling with substance use issues and concurrently facing severe mental health challenges, as well as addressing significant emotional issues in children. This center features customized treatment plans that encompass outpatient services for methadone/buprenorphine or naltrexone, cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. With particular attention to the needs of pregnant and postpartum women, Magnolia Medical Group serves individuals of all genders, including young adults. Its commitment to high-quality care and personalized treatment makes it a leading option for those in the Denver community seeking extensive addiction recovery services.

Maine Behavioral Healthcare

Situated in Portland, ME, Maine Behavioral Healthcare provides a wide array of services for substance use treatment and tailored support for those facing co-existing mental health challenges. The center offers an intensive outpatient program, standard outpatient services, and treatment alternatives like methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, cognitive behavioral therapy, and brief interventions, this facility is designed to assist adult women, trauma survivors, and individuals dealing with both mental health and substance use issues. Maine Behavioral Healthcare accommodates adults and seniors of every gender, delivering quality care and individualized rehabilitation services to meet diverse needs.

Malcolm Randall VAMC
Gainesville, FL

Situated in Gainesville, FL, the Malcolm Randall VAMC delivers a wide range of rehabilitation services aimed at adults and older individuals dealing with substance use issues along with concurrent mental health challenges. This center features an intensive outpatient program, outpatient detox services, and diverse outpatient offerings employing methods like 12-step support, anger management, and short-term interventions. With distinctive programs designed for active duty personnel and specific services for adult men and women, the center focuses on personalized treatment based on the unique requirements of each client. It accommodates both male and female participants, fostering an encouraging and welcoming atmosphere for anyone pursuing recovery.

Malibu Detox and Residential

Situated in Topanga, CA, Malibu Detox and Residential provides extensive programs for addiction recovery. This center is known for its detox services and treatment for substance abuse, offering round-the-clock residential care and short-term options. It employs methodologies such as 12-step facilitation, anger management techniques, and brief interventions, serving adult males, females, and active military personnel. Targeting both adults and young adults, the facility offers tailored support for its male and female clients. Malibu Detox and Residential is dedicated to providing personalized, high-quality care to assist individuals in their recovery journey.

MPower Wellness of Pennsylvania LLC

MPower Wellness of Pennsylvania LLC, located in Exton, PA, delivers robust programs for substance abuse and specialized support for those facing concurrent mental health and addiction challenges. The facility features intensive outpatient services, day treatment options, and partial hospitalization for adults and young adults. Their approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies, specifically addressing trauma survivors and individuals with dual diagnoses. MPower Wellness of Pennsylvania LLC provides gender-inclusive, high-quality care to aid individuals in their path toward lasting recovery.

Malibu Recovery Center
Studio City, CA

Malibu Recovery Center, situated in Studio City, CA, delivers thorough care for adults struggling with addiction, particularly when accompanied by severe mental health concerns or developmental challenges in children. Their offerings include robust intensive outpatient and standard outpatient services, encompassing day treatment and partial hospitalization options. The center has distinct programs tailored for adult men, adult women, and individuals who have faced trauma, accommodating a wide spectrum of needs. Employing methods like 12-step support, anger management techniques, and brief intervention strategies, Malibu Recovery Center is committed to delivering personalized support. Serving adult men and women, as well as young adults, Malibu Recovery Center is focused on providing excellent, customized recovery solutions.

Magnolia Medical Group
Wheat Ridge, CO

Magnolia Medical Group located in Wheat Ridge, CO, specializes in outpatient treatment for adults dealing with substance use disorders alongside severe mental health challenges, as well as treatment for children facing significant emotional difficulties. The facility offers outpatient options including methadone/buprenorphine or naltrexone therapies, cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. There are specific programs designed for pregnant and postpartum women. Catering to both adult and young adult clients, the center provides personalized care for individuals regardless of gender. With its comprehensive and specialized services, it stands out as an excellent option for those in need of effective rehabilitation solutions in the Wheat Ridge community.

Magnolia Womens Recovery Program

Magnolia Women's Recovery Program in Oakland, CA, provides in-depth, long-term residential care for adult women experiencing substance use disorders and related serious mental health challenges. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies to guide individuals through their healing process. A distinctive aspect of their offerings includes specialized support for women who have experienced intimate partner violence, domestic abuse, or sexual assault. Serving adult, senior, and young adult women, the center ensures constant care within a secure and nurturing setting. For those looking for thorough and empathetic support, this establishment is committed to empowering women to conquer addiction and regain control of their lives.

Magnolia Recovery
Shreveport, LA

Situated in Shreveport, LA, Magnolia Recovery presents a wide array of treatment programs for substance use aimed at both adults and youth, including those who face significant mental health challenges or emotional issues. The center focuses on intensive outpatient services, outpatient treatment, and medication-assisted options using methadone, buprenorphine, or naltrexone. Emphasizing therapies such as anger management, cognitive behavioral therapy, and the Matrix Model, this facility is designed to meet the specific requirements of active duty military personnel, young people, and adult males. Magnolia Recovery provides inclusive services for both genders, dedicated to delivering effective and compassionate support to those seeking recovery from addiction.

Mahajan Therapeutics

Mahajan Therapeutics, located in Ironton, OH, specializes in the treatment of substance use disorders for adults who are also dealing with serious mental health challenges. The center features both intensive outpatient and outpatient programs, incorporating treatments such as methadone, buprenorphine, and naltrexone therapy. Utilizing various methods like 12-step facilitation, anger management, and brief intervention strategies, the facility is equipped to meet the specific needs of active military members, adolescents, and adult males. Mahajan Therapeutics provides comprehensive support for adult clients of all genders, ensuring that its programs are customized to effectively address the dual issues of substance use and mental health.

Malvern Treatment Center

Situated in Malvern, PA, the Malvern Treatment Center delivers extensive detox and addiction treatment services aimed at both adults and young adults. This center is adept at handling co-occurring substance use issues alongside significant mental health conditions. It offers residential detox and short-term residential care, utilizing methods like 12-step facilitation, anger management, and brief intervention to ensure high-quality treatment. Customized programs for men, women, and individuals with trauma backgrounds promote personalized care. The center’s emphasis on catering to the specific needs of different genders and age groups distinguishes it as a compassionate and effective choice for rehabilitation.

Malvern Treatment Centers

Malvern Treatment Centers, situated in Philadelphia, PA, delivers extensive programs for detoxification and substance use disorder treatment. They provide inpatient detox, round-the-clock residential care, and shorter-term residential options. Employing therapeutic techniques like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the center serves adults and young adults of all genders. Recognizing diverse needs, Malvern Treatment Centers offers distinct programs for active military personnel, adult males, and adult females, guaranteeing personalized attention. Esteemed for its high-quality care and customized assistance, this institution is a leading destination for individuals pursuing successful recovery from addiction.

Placeholder image

The Macoupin County Public Health Department, situated in Gillespie, IL, offers outpatient care for individuals, both adults and young adults, who are dealing with substance use disorders and co-occurring mental health issues. This center provides several treatment avenues, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Employing proven methods like cognitive behavioral therapy and contingency management, the program emphasizes personalized recovery plans for all clients, regardless of gender. Their dedication to effective treatment and high standards makes them a strong choice for those pursuing recovery from addiction and mental health concerns.

Placeholder image

The Macoupin County Public Health Dept in Carlinville, IL provides extensive rehabilitation programs. This clinic focuses on addiction recovery for adults and adolescents, particularly those facing dual diagnoses such as significant mental health challenges or emotional disorders. Services include outpatient care, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside consistent outpatient counseling. Emphasizing personalized support, the facility offers interventions like anger management, brief counseling, and cognitive behavioral therapy. Their tailored treatment strategies are designed to support both male and female individuals on their journey to recovery and improved health.

Placeholder image

The Macoupin County Public Health Dept located in Litchfield, IL, provides extensive outpatient services for individuals grappling with substance use issues and related mental health challenges. The center features specialized programs designed to meet the unique needs of both adults and children, including anger management, brief interventions, and cognitive behavioral approaches. Offering access to outpatient options such as methadone, buprenorphine, or naltrexone treatment, alongside regular outpatient support, they emphasize a comprehensive recovery strategy. Catering to individuals of all genders, this facility is committed to delivering high-quality care through tailored treatment plans. For those in need of effective, evidence-supported rehabilitation, this center is focused on aiding you in achieving sustainable recovery.

Placeholder image

Situated in Marshall, NC, the Madison County Health Department delivers extensive support for substance use disorders through its outpatient services. The center specializes in the administration of methadone, buprenorphine, and naltrexone treatments, employing motivational interviewing techniques to assist clients on their path to recovery. This facility is designed for adult men and women, including those who have faced intimate partner violence or domestic abuse. Catering to all genders, the center fosters a secure and welcoming atmosphere for individuals pursuing addiction treatment. Committed to high-quality care and proven methods, the Madison County Health Department aims to help individuals attain sustainable recovery.

Placeholder image

Maine Behavioral Healthcare, located in Springvale, ME, provides an extensive range of substance use treatments along with specialized services for individuals facing concurrent mental health challenges. The center offers various levels of care, including intensive outpatient, outpatient, and standard outpatient programs suited for adults and seniors. Emphasizing anger management, brief intervention techniques, and cognitive behavioral therapy, the facility customizes treatment approaches to fit the specific requirements of each person. There are dedicated programs for clients who have undergone trauma and those dealing with both mental health and substance use disorders. Maine Behavioral Healthcare is committed to serving both men and women, ensuring they receive exceptional care to aid in their recovery journey and overall health.

Placeholder image
Huntingdon, PA

Mainstream Counseling in Huntingdon, PA, delivers a complete suite of addiction recovery services designed for each person's unique situation. Their offerings include intensive outpatient programs, standard outpatient services, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Specializing in areas such as anger management, brief intervention strategies, and cognitive behavioral therapy, Mainstream Counseling supports young people, individuals who have experienced trauma, and those navigating the legal system. The center is equipped to assist both adults and younger individuals, accommodating male and female patients who require tailored support in a nurturing atmosphere. Opt for Mainstream Counseling for proven therapeutic methods and caring assistance as you pursue lasting sobriety.

Placeholder image

In Willow Grove, PA, Malvern Treatment Centers stands as a leading facility providing all-encompassing substance abuse recovery programs for adults and adolescents. The center features inpatient detox, round-the-clock residential support, and short-term residential care designed for individuals battling addiction and co-occurring psychological issues. Their expertise includes 12-step integration, emotional regulation techniques, and concise therapeutic approaches. Malvern Treatment Centers welcomes all genders, including those healing from traumatic experiences, and is dedicated to delivering exceptional, personalized care to foster lasting recovery within a secure and healing atmosphere.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)