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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Metro Treatment of Florida LP

Metro Treatment of Florida LP, located in Pinellas Park, FL, specializes in outpatient detox services and programs aimed at addressing substance use issues. The center administers treatments such as methadone, buprenorphine, and naltrexone. Tailored to meet the needs of adult men, adult women, pregnant and postpartum women, as well as young adults, the facility employs various therapeutic methods, including anger management, brief intervention, and cognitive behavioral therapy. Prioritizing personalized care, this center serves both male and female clients, adhering to high standards and evidence-based strategies to promote recovery. If you are looking for thorough addiction treatment within a nurturing setting, Metro Treatment of Florida LP is committed to assisting individuals in overcoming their substance use difficulties.

Metro Treatment of Florida LP

Metro Treatment of Florida LP, located in Tarpon Springs, FL, specializes in outpatient detox and treatment for substance use among both adults and young adults. The facility caters to specific populations, including adult males, adult females, and pregnant or postpartum women, providing tailored care. Their treatment methods encompass anger management, brief interventions, and cognitive behavioral therapy. Emphasizing high-quality care, the center offers outpatient services utilizing methadone, buprenorphine, or naltrexone, designed to address the unique needs of male and female clients in their recovery journey from addiction.

Metro Treatment of Texas LP

Metro Treatment of Texas LP, located in San Antonio, TX, provides comprehensive outpatient services for individuals struggling with substance use disorders and co-occurring mental health conditions. Their approach encompasses adults, young adults, and children, addressing a range of needs from general substance use to serious mental health illnesses and emotional disturbances. The center employs evidence-based practices such as cognitive behavioral therapy, anger management techniques, and brief intervention strategies to craft personalized treatment plans. Specialized programs are available for adult men and women, ensuring focused support. At Metro Treatment of Texas LP, client well-being is paramount, with medically supervised outpatient treatments including methadone, buprenorphine, or naltrexone available to all eligible individuals.

MetroHealth
Cleveland, OH

MetroHealth, located in Cleveland, OH, specializes in tailored substance use treatment programs designed for both adults and young adults. The center offers a variety of services, including intensive outpatient programs, standard outpatient care, and options for methadone, buprenorphine, or naltrexone treatments. Emphasizing cognitive behavioral therapy, the Matrix Model, and motivational interviewing, MetroHealth crafts a unique recovery plan for each individual, ensuring that the treatment is personalized. The center's strong focus on customized care distinguishes it, serving both male and female clients alike. If you are looking for thorough addiction treatment delivered with compassion and expertise, MetroHealth is committed to aiding you on your path to sustained sobriety.

Metropolitan Community Hlth Servs Inc

Metropolitan Community Hlth Servs Inc, located in Williamston, NC, provides outpatient treatment for substance use and offers specialized services for adults dealing with co-occurring substance use and serious mental health issues, as well as for children experiencing severe emotional disturbances. The center features therapy options such as outpatient methadone/buprenorphine and naltrexone treatments, along with standard outpatient services. Their methodologies include 12-step programs, anger management techniques, and brief intervention strategies. This facility also has specialized initiatives designed for adolescents, men, and women, accommodating adults and seniors of all genders. Metropolitan Community Hlth Servs Inc is committed to delivering personalized, high-quality care to support clients throughout their recovery journey.

Metropolitan Community Hlth Servs Inc

Metropolitan Community Hlth Servs Inc located in Washington, NC, delivers extensive treatment for adults dealing with substance use issues alongside serious mental health conditions or emotional challenges in children. The center provides outpatient programs, offering options such as methadone, buprenorphine, and naltrexone therapies, in addition to standard outpatient services. Their treatment strategy incorporates 12-step help, anger management techniques, and brief intervention methods, ensuring that care is customized to each individual’s needs. With specific programs directed toward adolescents, and adult men and women, the facility serves a wide range of populations. Adults and older adults of all genders can benefit from tailored treatment plans within a nurturing environment recognized for its commitment to quality care and personalized rehabilitation strategies.

Michaels House
Palm Springs, CA

Michael's House, located in Palm Springs, California, provides a wide range of rehabilitation services for both adults and young adults struggling with substance use disorders along with associated mental health challenges. The center features inpatient detox and treatment within a hospital setting, catering specifically to adult men, adult women, and those who have faced trauma. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention, this facility guarantees individualized care designed to meet the unique needs of each patient. With services available for both genders, Michael's House is committed to offering effective treatment in a nurturing atmosphere to support lasting recovery.

Michaels House
Palm Springs, CA

Situated in Palm Springs, CA, Michaels House delivers an extensive variety of treatment services for substance use disorders aimed at adults and young adults. The center focuses on addressing co-occurring substance use issues alongside significant mental health challenges or emotional problems in children. With a range of options such as intensive outpatient programs, outpatient day treatment, and partial hospitalization, Michaels House emphasizes personalized treatment plans that cater to the unique requirements of each individual. The facility provides specialized programs for adult men, adult women, and those who have faced trauma. By incorporating methods like 12-step facilitation, anger management, and brief interventions, Michaels House guarantees top-notch care for all clients pursuing recovery.

Mid Coast/Parkview Health

Mid Coast/Parkview Health, located in Brunswick, ME, provides an array of addiction rehabilitation services specifically designed for both adults and older adults. The center features detox services, treatment for substance use disorders, and focused care for individuals facing dual diagnosis challenges. Treatment options encompass intensive outpatient programs as well as outpatient detoxification. The facility employs proven strategies such as cognitive behavioral therapy and motivational incentives to aid individuals on their recovery journey. With tailored programs for adult males, adult females, and those with co-occurring mental health issues, Mid Coast/Parkview Health is dedicated to delivering personalized treatment. Their commitment to high-quality care and gender-specific offerings makes this center a reliable option for those looking for effective recovery solutions.

Mid Hudson Valley Div of WMC

The Mid Hudson Valley Division of WMC, located in Poughkeepsie, NY, provides extensive treatment options for substance use disorders through its inpatient hospital services and around-the-clock care programs. This center employs various specialized techniques, including 12-step programs, anger management, and cognitive behavioral therapy, to meet the unique needs of each individual. It also features specific programs designed for active military personnel, as well as separate services for adult men and women, reflecting its commitment to serving a wide range of individuals. The facility welcomes adults and young adults of all genders, fostering a nurturing and inclusive atmosphere. Clients can anticipate receiving top-notch care and evidence-based therapies to support them on their path to recovery.

Mid Hudson Valley Div of WMC

The Mid Hudson Valley Division of WMC, located in Poughkeepsie, NY, provides a range of extensive treatment options for addiction. This center features hospital-based inpatient detoxification services and addresses substance use disorders while also accommodating adults with serious mental health issues and children with emotional challenges. It offers tailored programs for men, women, and individuals impacted by domestic violence, ensuring a broad spectrum of services. Utilizing methods such as 12-step programs and anger management, the center prioritizes personalized support for both adults and younger individuals. Committed to high-quality care grounded in evidence-based practices, this facility offers compassionate and effective rehabilitation for all clients.

Metro Treatment of Florida LP

Metro Treatment of Florida LP in Saint Augustine, FL, delivers outpatient care for adults and young adults grappling with substance use. This facility offers methadone, buprenorphine, or naltrexone outpatient programs within a nurturing setting. Focusing on counseling for substance use disorders, the center serves both men and women. Dedicated programs are also accessible for expectant and new mothers needing thorough support. Metro Treatment of Florida LP is committed to providing excellent care and customized treatment strategies to aid individuals in their recovery path.

Metro Treatment of Florida LP

Metro Treatment of Florida LP, located in Tampa, FL, provides comprehensive outpatient substance abuse recovery services. Their programs encompass medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Utilizing scientifically validated methods including cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, the center guides individuals on their journey to sobriety. Tailored support is offered to pregnant and postpartum women, as well as veterans. The facility welcomes adults and young adults of all gender identities, emphasizing personalized treatment plans and effective therapeutic interventions within a nurturing setting. For those in search of thorough and caring addiction treatment, Metro Treatment of Florida LP is a recommended choice.

Metro Treatment of Florida LP

Metro Treatment of Florida LP, located in Fort Lauderdale, FL, features outpatient services for substance dependency and withdrawal management, with a particular focus on medication-assisted treatment using methadone, buprenorphine, or naltrexone. This establishment delivers comprehensive support to adult men, adult women, expectant and new mothers, and young adults. Employing therapeutic methods such as 12-step integration, emotional regulation techniques, and short-term counseling, the center is equipped to assist a broad spectrum of individuals pursuing recovery. A distinguishing aspect of their program is the provision of gender-specific counseling for both male and female patients, fostering a personalized care environment to address individual recovery journeys. Discover tailored and impactful recovery solutions at Metro Treatment of Florida LP.

Mid Columbia Center for Living

Mid Columbia Center for Living, located in The Dalles, OR, provides various treatment options for substance use disorders alongside specialized care for individuals with concurrent mental health issues, suitable for both adults and children. The center features intensive outpatient and outpatient programs, offering treatments like methadone and buprenorphine. Their approach is personalized, employing evidence-based methods including 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center also offers distinct programs designed for adult men, adult women, and clients facing dual diagnoses, accommodating adults and seniors of diverse genders. Emphasizing high-quality care and individualized approaches, this facility is dedicated to fostering recovery and promoting overall well-being.

Metro Treatment of Florida LP

Metro Treatment of Florida LP, located in Pompano Beach, FL, specializes in outpatient treatment for substance use, emphasizing high-quality care and personalized assistance. The facility provides various treatment options, including outpatient methadone/buprenorphine and naltrexone programs, as well as regular outpatient care and counseling for substance use disorders. They also offer telemedicine and telehealth services. This center features specialized programs designed for adult men, adult women, and pregnant or postpartum individuals, addressing a wide range of needs. By serving adults and young adults of all genders, Metro Treatment of Florida LP promotes a holistic approach to recovery. Experience customized care in a nurturing atmosphere at this esteemed rehabilitation facility.

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Situated in Arabi, LA, the Metropolitan Human Services District provides focused treatment for adults grappling with substance use issues alongside mental health challenges, as well as support for children facing serious emotional difficulties. Their range of services encompasses intensive outpatient care, standard outpatient support, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. By employing evidence-supported methodologies such as cognitive behavioral therapy, contingency management, and the Matrix Model, this center delivers customized care for adolescents, adults, and older adults. The Metropolitan Human Services District prioritizes personalized treatment strategies and offers gender-specific programs for both men and women, ensuring comprehensive and effective support for sustained recovery.

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Located in Miami, FL, Miami Dade CAHSD offers extensive treatment services for individuals dealing with substance use issues. The center provides a variety of recovery options, including long-term residential care, outpatient support, and day programs, with a focus on 12-step methods, anger management, and cognitive behavioral techniques. Special programs are designed for adult men, adult women, and individuals who have faced trauma. Emphasizing personalized care, this facility customizes its approach to address each client's unique challenges. Serving both genders, Miami Dade CAHSD fosters a welcoming and supportive atmosphere for those on the path to overcoming addiction and reclaiming their lives.

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Michiana Behavioral Health, situated in Plymouth, Indiana, stands as a leading addiction treatment center. They deliver extensive care for individuals battling substance abuse, chemical dependency, and co-occurring psychological disorders, serving both adolescents and adults. The facility offers inpatient medical detox and therapeutic services, emphasizing the 12-step model, cognitive behavioral techniques, and strategies for sustained sobriety. Michiana Behavioral Health also features distinct programs designed for active military members, adult men, and women. Their dedication to high-quality, personalized recovery plans positions them as an excellent option for adults and young adults pursuing a life free from addiction.

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At Mid Coast/Parkview Health in Damariscotta, ME, adults and seniors facing addiction and co-occurring mental health challenges discover a range of complete recovery support. Their offerings encompass detox services, structured outpatient treatment, and less intensive outpatient detox options. Employing proven methods such as cognitive behavioral therapy and contingency management, they guide individuals toward healing. The facility distinguishes itself with distinct programs designed for adult men, adult women, and those managing dual diagnoses, ensuring personalized care plans. By emphasizing brief intervention and motivational rewards, Mid Coast/Parkview Health delivers effective and high-standard treatment for all individuals pursuing sobriety.

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Mid Columbia Center for Living, located in Hood River, OR, delivers thorough recovery programs focused on addiction and intertwined mental health conditions affecting both young people and adults. The center offers various levels of care, including intensive outpatient services, general outpatient support, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing evidence-based approaches like 12-step integration, motivational interviewing, and cognitive behavioral therapy, the center creates customized plans for each person. Specific support is available for adult men, adult women, and individuals facing dual diagnoses of mental health and substance use challenges. Catering to a broad age range from adults to seniors and all genders, this establishment prioritizes high-quality, individualized treatment designed to guide each person through their personal path to wellness.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)