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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Mirror Inc
Holton, KS

Mirror Inc, located in Holton, KS, provides a variety of programs for individuals dealing with substance abuse, catering to adults, seniors, and youths. The facility features intensive outpatient options, general outpatient care, and specific treatments such as methadone or buprenorphine/naltrexone therapy. It includes tailored programs for active duty military personnel and adult males, emphasizing 12-step methods, anger management, and brief intervention strategies. Mirror Inc is committed to delivering high-quality support for both men and women, making it an excellent resource for those in the Holton region seeking customized addiction recovery solutions.

Mirror Lake Recovery Center

Mirror Lake Recovery Center, situated in Burns, TN, delivers thorough addiction care for adults and young adults. They provide extended residential stays, detox services, and round-the-clock residential care. This center focuses on addressing substance use disorders and trauma, with customized plans for adult men and women. Employing 12-step facilitation, anger management techniques, and brief intervention strategies, the center guarantees personalized support. Mirror Lake Recovery Center is dedicated to providing excellent care for its male and female clients as they pursue lasting recovery in a nurturing setting.

Mission Harbor Behavioral Health

Situated in the beautiful city of Santa Barbara, California, Mission Harbor Behavioral Health delivers focused rehabilitation services for those dealing with substance abuse issues and concurrent mental health disorders. The center features intensive outpatient programs, outpatient care, and day treatment options specifically designed for adults facing significant mental health struggles, as well as emotional challenges in children. Emphasizing approaches such as 12-step support, anger management, and cognitive behavioral therapy, Mission Harbor Behavioral Health provides thorough treatment tailored for adult men, adult women, and teenagers. The facility supports both genders, fostering an inclusive and empathetic atmosphere for individuals pursuing effective rehabilitation in a serene environment.

Mission Treatment Services Inc

Mission Treatment Services Inc, located in San Diego, CA, specializes in outpatient detox and treatment programs for both adults and young adults dealing with substance use issues. The facility tailors its services to accommodate active duty military members, as well as adult men and women. Their therapeutic methods incorporate motivational interviewing, relapse prevention strategies, and contingency management. Committed to delivering high-quality care, the center provides outpatient treatments using methadone/buprenorphine and naltrexone. By serving both genders, Mission Treatment Services Inc aims to offer supportive and effective rehabilitation services to help individuals navigate their path to recovery.

Mississippi Drug and Alcohol

The Mississippi Drug and Alcohol center located in Biloxi, MS, specializes in delivering thorough addiction recovery services for both adults and young adults facing challenges related to substance abuse and coexisting mental health disorders. This facility offers inpatient detox and treatment options, with programs specifically designed for active duty military members as well as adult men and women. Utilizing methods such as 12-step facilitation, cognitive behavioral therapy, and anger management, the center formulates personalized treatment strategies based on the unique requirements of each client. Individuals can anticipate receiving high-quality care in a gender-sensitive setting aimed at fostering sustainable recovery. For those in search of effective and customized addiction rehabilitation, this center is committed to guiding you towards sobriety and improved mental health.

Missouri Baptist Sullivan Hospital

Missouri Baptist Sullivan Hospital, located in Sullivan, MO, provides thorough detox services for both adults and young adults within a hospital inpatient environment. The program features round-the-clock support that emphasizes 12-step facilitation, strategies for relapse prevention, and counseling for substance use disorders. Treatment plans are customized to meet the specific needs of each patient, promoting a tailored recovery experience. With distinct programs designed for male and female clients, Missouri Baptist Sullivan Hospital is dedicated to delivering high-quality care and assistance for individuals working to conquer addiction.

Modern Psychiatry and Wellness LLC

Modern Psychiatry and Wellness LLC, located in West Chester, OH, provides an extensive array of services designed to assist both adults and children dealing with mental health issues and substance use disorders. The center specializes in detoxification, intensive outpatient programs, and day treatment options that are customized to cater to individual needs. With a focus on co-occurring disorders, the facility features specialized programs for active duty service members, teenagers, and adult males. Employing evidence-based methodologies, such as 12-step involvement and anger management techniques, this center ensures a high standard of care for all clients, regardless of gender. If you're looking for tailored treatment in a nurturing setting, this facility is committed to supporting your journey toward recovery.

Momenta Recovery
Glenwood Springs, CO

Momenta Recovery, situated in Glenwood Springs, CO, stands as a premier facility dedicated to the recovery of adult women struggling with substance use disorders. The center provides comprehensive treatment, including intensive outpatient programs, 12-step facilitation, anger management techniques, and brief intervention strategies. They offer specialized support for those who have endured intimate partner violence, domestic abuse, and sexual assault. Momenta Recovery also addresses the complex needs of individuals facing co-occurring substance use and severe mental health conditions. Their services are tailored for adult women, seniors, and young adults, promoting a path to healing and lasting sobriety.

Mirmont Treatment Center

Mirmont Treatment Center, situated in Media, PA, delivers a variety of specialized services aimed at helping adults and young adults grapple with addiction. The facility features detoxification programs, treatment for substance use, and support for co-occurring mental health disorders. It offers multiple levels of care, including intensive outpatient, outpatient, and day treatment, all rooted in evidence-based practices such as 12-step programs, anger management techniques, and brief intervention strategies. Additionally, Mirmont has designed specific programs for active duty service members, as well as distinct services for adult men and women. This center prioritizes comprehensive care and assistance for individuals striving for recovery from addiction and mental health issues.

Mohave Mental Health Clinic Inc

Located in Lake Havasu City, AZ, Mohave Mental Health Clinic Inc provides an array of outpatient services designed specifically for those dealing with substance use issues, concurrent mental health challenges, and trauma. The clinic offers detox services, treatment for substance use disorders, and programs aimed at adults experiencing severe mental health issues, as well as children facing emotional challenges. Treatment methods utilized include anger management, cognitive behavioral therapy, and brief therapeutic interventions. The facility provides outpatient detoxification and treatments involving methadone, buprenorphine, or naltrexone for both men and women. Prioritizing high-quality care, the clinic features specialized programs tailored for trauma victims and individuals with co-occurring conditions, assisting adults and young adults in need of thorough rehabilitation support.

Mirror Inc
Shawnee, KS

Located in Shawnee, KS, Mirror Inc provides a wide array of services designed for addiction recovery. This center features intensive outpatient care, long-term residential options, and standard outpatient programs that prioritize treatment for substance use issues alongside mental health challenges. Their unique strategies involve 12-step support, anger management sessions, and short-term interventions. Mirror Inc serves adult men and women, as well as young adults, offering targeted programs for those who have been affected by intimate partner violence. With a strong emphasis on personalized care, this facility is notable for its customized treatment approaches and transitional housing services, making it an essential asset for individuals on their path to recovery.

Mirror Inc
Newton, KS

Situated in Newton, KS, Mirror Inc provides an extensive array of substance abuse treatment options designed for both adults and young adults. This center offers intensive outpatient therapies, long-term residential care, and general outpatient services, implementing methods like 12-step facilitation, anger management, and brief intervention techniques. Mirror Inc has specialized programs catering to active duty military members as well as adult men and women, ensuring there are appropriate facilities for all clients. With an emphasis on personalized care and tailored treatment strategies, Mirror Inc is committed to helping individuals achieve their recovery and sobriety goals.

Mohave Mental Health Clinic Inc

Mohave Mental Health Clinic Inc, located in Bullhead City, AZ, provides a wide array of outpatient services designed to treat substance use issues and concurrent mental health problems in both adults and children. Their offerings encompass detoxification, outpatient therapy, and tailored support for those with trauma histories. Employing techniques like cognitive behavioral therapy and anger management, the clinic ensures personalized care for men, women, and young adults. Committed to high-quality, evidence-supported methods, this center aims to assist clients as they progress towards recovery.

Mohave Mental Health Clinic Inc

Mohave Mental Health Clinic Inc, located in Kingman, AZ, provides outpatient detox services as well as treatment for substance use disorders and co-occurring mental health issues for both adults and children. The center focuses on offering tailored support for individuals with a history of trauma and those facing dual diagnoses. Employing various therapeutic methods such as cognitive behavioral therapy, anger management, and brief intervention, this facility addresses the specific requirements of every patient. Catering to both male and female clients, including young adults, Mohave Mental Health Clinic Inc prioritizes quality care within a nurturing atmosphere. Opt for this center for thorough and individualized rehabilitation services in the Kingman region.

Momentum Center LLC
Saint Cloud, MN

Situated in Saint Cloud, MN, Momentum Center LLC provides exceptional treatment for substance use and transitional housing services exclusively for adult males. This center is dedicated to offering long-term residential support, utilizing approaches such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. It welcomes men across all age groups, from young adults to seniors, fostering a nurturing atmosphere that promotes healing. Momentum Center LLC is distinguished by its thorough residential programs designed to address the specific challenges faced by male clients on their journey to recovery and health.

Mirror Inc
Hiawatha, KS

Situated in Hiawatha, KS, Mirror Inc specializes in high-quality addiction treatment for both adults and seniors. The center provides various services, including intensive outpatient programs, outpatient care, and treatments with methadone or buprenorphine and naltrexone, addressing a wide range of individual needs. Employing methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, Mirror Inc guarantees thorough treatment. The facility also features dedicated programs for active military personnel, adolescents, and adult men, ensuring customized support. Catering to both men and women, Mirror Inc is committed to offering effective, personalized rehabilitation solutions to help individuals attain sustainable recovery.

Mirror Inc
Topeka, KS

Mirror Inc in Topeka, KS, provides extensive support for those overcoming addiction. Their offerings include a variety of care levels, from around-the-clock inpatient stays to flexible outpatient programs and extended residential care, serving both adult men and women, as well as young adults. The facility excels in specific therapeutic interventions such as facilitating the 12-step program, teaching anger management techniques, and employing brief intervention strategies to meet diverse client needs. Mirror Inc stands out with specialized services designed for active duty military personnel, adult men, and adult women, creating a distinct and nurturing space for recovery.

Mirror Inc
Topeka, KS

Mirror Inc, situated in Topeka, KS, delivers a full spectrum of care for individuals of all ages struggling with addiction and co-occurring mental health conditions. The facility offers various levels of support, including intensive outpatient, standard outpatient, and medication-assisted treatment using methadone or buprenorphine. Their therapeutic approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies, all customized to each client's unique journey. Mirror Inc also features specialized services designed for active military members, teenagers, and adult men. Available to both men and women, the center is committed to providing effective treatment for those navigating the complexities of substance dependence and psychological well-being.

Moab Regional Recovery Center

The Moab Regional Recovery Center, situated in Moab, UT, provides extensive outpatient services aimed at detoxification, substance use treatment, and the management of co-occurring disorders for both adults and children. By employing methods such as anger management, cognitive behavioral therapy, and customized treatment plans, this center ensures high-quality care for individuals of all genders, including seniors. With a focus on specialized outpatient detox and treatments like methadone or buprenorphine, the center emphasizes tailored care to meet the distinct needs of each person. For those looking for effective and personalized addiction recovery in a nurturing setting, the Moab Regional Recovery Center serves as an essential support on the journey to healing.

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Mission Hospital Copestone, located in Asheville, NC, specializes in addressing substance abuse as well as severe mental health issues in adults and significant emotional challenges in children. The facility offers inpatient care with 24-hour support options. Utilizing techniques like brief intervention, cognitive behavioral therapy, and motivational interviewing, they customize treatment according to each person's requirements. The center features specialized programs for active-duty military members, teenagers, and adult males. Focusing on the well-being of both men and women, Mission Hospital Copestone is committed to delivering exceptional care through tailored, comprehensive treatment strategies.

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Mississippi State Hospital, situated in Whitfield, MS, delivers thorough care for individuals of all ages struggling with addiction. Their services include inpatient detoxification and treatment within a hospital setting, with a particular expertise in addressing dual diagnoses of substance use disorders and severe mental health conditions in adults, alongside emotional challenges in children. The center utilizes approaches such as 12-step facilitation, cognitive behavioral therapy, and anger management, customizing each treatment plan to the specific requirements of every patient. Mississippi State Hospital is equipped to provide specialized care for adult women, teenagers, and those affected by intimate partner violence, guaranteeing effective and empathetic support across all genders.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)