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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Monarch
Rocky Mount, NC

Monarch, situated in Rocky Mount, NC, stands out as a premier rehabilitation center providing an extensive array of tailored treatment options. The center specializes in outpatient services for individuals dealing with substance use disorders, alongside addressing co-occurring substance use and significant mental health issues for adults, as well as serious emotional challenges in children. Monarch facilitates outpatient treatments involving methadone/buprenorphine and naltrexone, in addition to standard outpatient care. The center employs a multitude of therapeutic techniques, such as cognitive behavioral therapy, anger management, and motivational interviewing. With dedicated programs for active military personnel, teenagers, and adult males, Monarch serves a wide demographic. It is devoted to delivering top-notch, personalized care for both adults and children/adolescents of all genders, ensuring a supportive environment throughout the recovery process.

Montco Recovery Center

Montco Recovery Center, situated in Colmar, PA, provides extensive treatment for substance use disorders catering to both adults and young adults. The center has a focus on co-occurring disorders and offers various treatment options, including intensive outpatient, outpatient, and day treatment programs. Among its services are 12-step facilitation, anger management strategies, and brief intervention techniques. The facility tailors its programs to meet the specific needs of adult men, adult women, and individuals facing concurrent mental health challenges, ensuring personalized attention for each client. Montco Recovery Center is committed to delivering high-quality care and support for those on the path to recovery from addiction and mental health issues.

Montefiore Medical Center

Montefiore Medical Center located in the Bronx, NY, provides a wide array of outpatient treatment options for substance use aimed at both adults and young adults. The center emphasizes care for those dealing with co-occurring substance use disorders alongside significant mental health challenges in adults, as well as serious emotional issues in children. Each treatment plan is crafted to meet the specific needs of clients. Various therapeutic methods are employed, such as brief interventions, cognitive behavioral therapy, and contingency management with motivational incentives. By concentrating on personalized care, the center guarantees that all clients, regardless of gender, receive effective and appropriate services. Montefiore Medical Center is committed to aiding individuals in their recovery journeys, whether they are looking for standard outpatient services or specialized outpatient treatments like methadone, buprenorphine, or naltrexone.

Montefiore Medical Center

Nestled in the Bronx, NY, Montefiore Medical Center delivers extensive addiction treatment and tailored support for individuals facing co-occurring substance use disorders and serious mental health challenges, encompassing both adults and children with significant emotional disturbances. The facility offers robust programs including intensive outpatient services, standard outpatient care, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing evidence-based strategies such as anger management techniques, brief intervention, and cognitive behavioral therapy, Montefiore Medical Center crafts individualized treatment plans. Dedicated services are available for adult men, adult women, and those with a history of trauma, serving adults and young adults across the gender spectrum with a commitment to high-quality, personalized care within a nurturing setting.

Montefiore Medical Center

Montefiore Medical Center, situated in Bronx, NY, delivers targeted outpatient care for addiction and co-occurring psychological health issues in both younger and adult populations. This facility utilizes a variety of scientifically validated methods, such as cognitive behavioral therapy and motivational incentives. Montefiore Medical Center prioritizes personalized treatment plans, adapting them to the specific requirements of every individual. The center supports adults and adolescents across the gender spectrum, offering outpatient medication management (methadone/buprenorphine or naltrexone) alongside general outpatient services. Montefiore Medical Center is committed to fostering sustained recovery for anyone looking for effective addiction treatment within a nurturing setting.

Montgomery County Dept Health/Human

Rockville, MD's Montgomery County Dept Health/Human provides outpatient support for adults struggling with substance use, particularly those also dealing with significant mental health conditions or emotional challenges in young people. Dedicated tracks are available for adult men and women, and for individuals who have faced domestic or intimate partner abuse. The therapeutic methods employed include 12-step encouragement, techniques for managing anger, and brief counseling. The center serves adults and young adults across all genders, committed to delivering high-quality, individualized care to foster lasting recovery and overall wellness.

Montrose Center
Houston, TX

Nestled in Houston, TX, Montrose Center provides a full spectrum of care for individuals and young people grappling with addiction. The center excels in addressing dual diagnoses, offering support for adults managing both substance use disorders and significant mental health conditions, as well as for children facing serious emotional challenges alongside substance issues. Utilizing intensive outpatient, outpatient, and standard outpatient modalities, Montrose Center integrates proven therapeutic methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. Specialized services are available for trauma survivors, people living with HIV/AIDS, and those with co-occurring mental health and substance use conditions. Montrose Center offers gender-inclusive rehabilitation, ensuring personalized care for every client.

Monroe Clinic
Monroe, NY

Monroe Clinic located in Monroe, NY, is dedicated to providing extensive treatment for substance use via its outpatient services. The center focuses on outpatient therapies involving methadone/buprenorphine or naltrexone, ensuring high-quality support through techniques such as brief interventions, cognitive behavioral therapy, and motivational incentives/contingency management. Monroe Clinic emphasizes customized care, offering specialized programs designed for teenagers, adult males, and adult females. The center accommodates a broad demographic, including adults, youth, and seniors, and is accessible to individuals of both genders seeking assistance with addiction. Patients can anticipate individualized support and research-backed methodologies at Monroe Clinic.

Monarch
Albemarle, NC

Monarch, situated in Albemarle, NC, serves as an outstanding rehabilitation facility dedicated to addressing substance abuse and concurrent severe mental health challenges in adults, along with emotional issues in children. The center delivers a variety of outpatient services, such as methadone and buprenorphine therapies alongside standard outpatient care. Their therapeutic methods include cognitive behavioral therapy, anger management, and motivational interviewing techniques. Monarch also features customized programs for active military members, teenagers, and adult males. By prioritizing individuals of all genders, this center is committed to providing exceptional support and care on the journey to recovery.

Montefiore Medical Center

Montefiore Medical Center, located in the Bronx, NY, provides a wide array of treatment options for substance use disorders, along with dedicated support for co-occurring severe mental health conditions in adults and emotional challenges in children. The center features outpatient programs that include methadone and buprenorphine therapies, emphasizing anger management, short-term interventions, and cognitive behavioral therapy. Catering to both adults and young adults of any gender, Montefiore tailors individual treatment plans within a nurturing atmosphere conducive to recovery. With a focus on delivering quality care through diverse therapeutic methods, Montefiore Medical Center is a reliable option for those in need of effective rehabilitation solutions.

Montefiore Medical Center

Montefiore Medical Center, located in the Bronx, NY, provides a wide variety of substance use disorder treatments. These options include intensive outpatient programs, outpatient care, and specialized methadone/buprenorphine or naltrexone services. Emphasizing methodologies like anger management, brief interventions, and cognitive behavioral therapy, the center serves a diverse population, including adults, children, adolescents, and young adults. There are unique programs designed specifically for younger individuals, ensuring their treatment is appropriately tailored. Catering to both males and females, the center focuses on delivering personalized, high-quality care to aid in the recovery process from addiction.

Montana Chemical Dependency Ctr

Situated in Butte, MT, the Montana Chemical Dependency Center provides targeted services for detoxification, addiction, and dual diagnosis mental health concerns for both adults and children. Their inpatient hospital care offers round-the-clock support and emphasizes 12-step strategies, anger management techniques, and brief intervention methods. With specialized programs designed for active duty service members, as well as for adult men and women, this center delivers gender-specific treatment options for adults and young adults. The Montana Chemical Dependency Center is committed to delivering personalized, high-quality care aimed at fostering recovery and promoting overall well-being for individuals battling addiction.

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Mon Yough Community Services, located in McKeesport, PA, specializes in comprehensive outpatient programs for adults dealing with substance use disorders and co-occurring mental health challenges. They also provide support for children experiencing emotional difficulties. The clinic offers medication-assisted treatment options including methadone, buprenorphine, and naltrexone, alongside targeted therapeutic interventions such as anger management, brief intervention, and cognitive behavioral therapy. Their approach is highly individualized, serving adults and seniors across all gender identities. Mon Yough Community Services stands out for its commitment to delivering high-quality, personalized care within a nurturing setting, making it a significant provider of effective addiction recovery services.

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West Portsmouth, OH

Monarch Health and Recovery, located in West Portsmouth, OH, delivers extensive rehabilitation services for both adults and adolescents facing addiction issues. This center specializes in detoxification, treatment for substance use disorders, and care for those dealing with both substance use and significant mental health challenges. Treatment options include intensive outpatient care, long-term residential stays, and outpatient sessions. With an emphasis on 12-step programs, anger management techniques, and brief intervention strategies, Monarch Health and Recovery customizes its approach to fit the specific requirements of each client. There are distinct programs for active military members, adult men, and adult women. Offering compassionate care in an encouraging setting, this facility supports both male and female individuals in their journey to recovery.

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Montefiore Medical Center in Bronx, NY, provides comprehensive outpatient services for individuals grappling with substance use disorders, particularly those also managing serious mental health conditions. Their treatment approach is rooted in evidence-based techniques, including cognitive behavioral therapy, motivational interviewing, and contingency management. The center offers medication-assisted treatment options such as methadone, buprenorphine, and naltrexone. Tailored support is available for distinct groups, including active duty military personnel, adult men, and women, ensuring that care plans are highly personalized. Montefiore Medical Center is committed to delivering high-quality, individualized care to both male and female patients, fostering a supportive environment for lasting recovery and overall well-being.

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Montgomery County Recovery Center, located in Norristown, PA, provides outpatient services for individuals struggling with substance use disorders, including treatments with methadone, buprenorphine, and naltrexone, in addition to standard outpatient care. The center features targeted programs tailored for adult men and women, as well as those who have faced domestic or intimate partner violence. Emphasizing a mix of 12-step guidance, anger management, and cognitive behavioral strategies, this facility serves both adults and young adults from all backgrounds. Montgomery County Recovery Center is distinguished by its holistic approach to addressing addiction and its dedication to delivering top-notch care for those on their path to recovery.

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Monticello, NY

Situated in Monticello, NY, Monticello delivers extensive detox services within a residential environment. This center ensures round-the-clock care for adult men and women, including young adults, with an emphasis on 12-step programs, anger management techniques, and brief intervention strategies. Monticello also offers tailored programs for clients dealing with trauma, accommodating a varied clientele. The facility's focus on personalized care and dedicated treatment plans positions it as an essential support system for individuals pursuing meaningful rehabilitation solutions.

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Monticello, NY

Situated in Monticello, NY, Monticello is dedicated to providing extensive outpatient treatment for adults facing substance use challenges alongside serious mental health disorders. The center's offerings extend to programs for both adults and younger individuals, featuring tailored services that emphasize anger management, brief interventions, and cognitive behavioral therapy. Committed to delivering high-quality care, this facility facilitates outpatient treatment options, including methadone/buprenorphine or naltrexone therapy, in addition to standard outpatient services. Monticello distinguishes itself with unique programs aimed at adolescents as well as separate services for adult men and women, ensuring personalized and effective care for every participant. The gender-specific treatment paths available create an accommodating and nurturing atmosphere for individuals on their journey to recovery.

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Monticello, NY

Situated in Monticello, NY, Monticello delivers extensive addiction recovery services aimed at adult males. The center specializes in detoxification, treatment for substance use, transitional accommodation, and options for sober living, all within a long-term residential framework. Monticello is dedicated to helping individuals who have faced issues such as intimate partner violence, domestic abuse, and sexual trauma. Emphasizing approaches like 12-step programming, anger management, and brief interventions, the facility serves a diverse clientele including adults, seniors, and young adults. Monticello's dedication to individualized care and high-quality support makes it a prime option for those seeking to conquer addiction in a nurturing and secure atmosphere.

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Monticello, NY

Nestled in Monticello, NY, Monticello stands as a trusted recovery facility, providing comprehensive specialized care for those in need of addiction and withdrawal management. This establishment features residential detox, round-the-clock residential care, and shorter-term residential options, all designed for adults and young adults. Monticello employs strategies such as 12-step support, emotional regulation training, and brief counseling methods. The center distinguishes itself with specific programs for adult males, adult females, and survivors of domestic or intimate partner abuse. Committed to high standards of care and personalized recovery paths, Monticello is devoted to guiding individuals toward sustained wellness.

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Monticello, NY

In Monticello, NY, Monticello is dedicated to providing extensive substance use treatment for adults, accommodating individuals with co-occurring serious mental health conditions or emotional challenges. The facility delivers outpatient care, day treatment programs, and partial hospitalization. They also offer distinct programs for adult men and women, and for those who have faced trauma. Employing proven techniques like cognitive behavioral therapy and anger management, Monticello emphasizes personalized recovery plans for adults and young adults. The center's gender-specific approach for men and women guarantees effective, customized support for sustained well-being.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)