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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Ardu Recovery Center

Ardu Recovery Center, located in Provo, UT, specializes in providing extensive addiction recovery programs for both adults and young adults. The center emphasizes the importance of detox and substance use therapy, offering various options such as intensive outpatient care, long-term residential stays, and standard outpatient services. Through methods including anger management, cognitive behavioral therapy, and brief interventions, personalized treatment is guaranteed. Additionally, the center features distinct programs aimed at serving active duty military personnel as well as specific services for adult men and women. Ardu Recovery Center is recognized for its dedication to delivering exceptional care coupled with a range of treatment alternatives.

Argus Community Inc

Argus Community Inc. in Bronx, NY, provides comprehensive long-term and round-the-clock residential care for adults struggling with substance use disorders and co-occurring serious mental health conditions. They also extend their services to children experiencing serious emotional disturbances. The facility is adept at utilizing therapeutic modalities such as 12-step facilitation, anger management techniques, and brief intervention strategies. Serving adults and young adults, regardless of gender, Argus Community Inc. offers tailored programs designed for individuals facing dual diagnoses of mental health and substance use challenges. Their commitment lies in offering personalized treatment grounded in proven methods, aiming to foster lasting recovery and enhance the overall health of their clients.

Arisa Health
Jonesboro, AR

Arisa Health in Jonesboro, AR, delivers extensive outpatient services for individuals of all ages struggling with substance abuse and intertwined mental health issues. The center employs a variety of scientifically validated methods, including cognitive behavioral therapy and the Matrix Model, to craft individualized treatment plans. Recognizing the unique requirements of clients involved with the criminal justice system and forensic services, Arisa Health extends specialized programming. Committed to providing excellent care and impactful treatments, the facility supports adults and seniors across all demographics, offering everything from brief counseling to day-long programs designed to guide each person toward lasting recovery.

Arisa Health
Springdale, AR

Arisa Health in Springdale, AR, delivers extensive outpatient substance abuse recovery options for individuals of all ages, particularly those facing dual diagnoses of serious mental health conditions or emotional challenges. Their personalized approach incorporates therapeutic techniques like anger management, cognitive behavioral therapy, and brief intervention strategies. Recognizing the distinct needs of different genders, Arisa Health offers tailored programs for men and women, fostering a secure space for healing. The center excels in outpatient treatment using methadone, buprenorphine, or naltrexone, customizing their services to individual client requirements. Discover exceptional treatment and dedicated support at Arisa Health.

Arista Recovery

Situated in Paola, KS, Arista Recovery delivers a full spectrum of care for adults and adolescents struggling with addiction and co-occurring mental health issues. Prioritizing personalized support, the center features residential detox, round-the-clock residential stays, and shorter residential programs. Arista Recovery employs proven therapeutic methods including 12-step integration, cognitive behavioral therapy, and the Matrix Model to guide patients toward healing. Catering to both men and women, this establishment is dedicated to providing superior, customized treatment aimed at fostering sustained recovery and enhanced mental health.

Arista Recovery at Overland Park

Arista Recovery at Overland Park, Kansas, delivers all-encompassing care for substance use disorders and targeted support for those facing co-occurring mental health conditions in adults or emotional challenges in youth. The facility offers multiple levels of care, such as intensive outpatient, outpatient services, and day treatment programs. Emphasizing methodologies like 12-step facilitation, anger management techniques, and brief intervention strategies, Arista Recovery serves adult men and women, including members of the armed forces. Their services are structured for adults and young adults, acknowledging the unique needs of each person on their journey to healing and sustained wellness.

Arizona Addiction Center

Situated in Scottsdale, AZ, the Arizona Addiction Center delivers exceptional treatment for adults and young adults grappling with substance use disorders alongside significant mental health challenges. This center offers round-the-clock residential support, short-term residential options, and targeted services for those who have undergone trauma. Emphasizing 12-step facilitation, anger management techniques, and brief intervention strategies, the facility develops personalized treatment plans for both men and women. With customized programs designed for different gender identities and age groups, this center is dedicated to providing high-quality care and comprehensive healing to assist clients in their recovery journey.

Arizona Recovery Center
Lake Havasu City, AZ

Arizona Recovery Center, located in Lake Havasu City, Arizona, provides outpatient substance use disorder services for adults, young people, and members of the armed forces. Their areas of expertise include anger management, brief intervention strategies, and cognitive behavioral therapy. Special attention is given to individuals with a history of trauma, domestic violence, or intimate partner violence, offering them personalized support. The center is dedicated to customized recovery plans, including outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, available to all genders. Arizona Recovery Center is committed to delivering excellent care through its thorough programs and skilled professionals, fostering a nurturing setting for individuals pursuing recovery.

Arkansas River Valley Area Council

Situated in Russellville, AR, the Arkansas River Valley Area Council provides focused treatment for substance use and dual mental health disorders affecting both adults and children. Offering a variety of options that include intensive outpatient, long-term residential, and outpatient care, this center delivers personalized support with methods such as 12-step facilitation, anger management, and brief intervention techniques. Specialized programs are designed for active military members, as well as adult men and women, ensuring services for all genders among adults and young adults. The center's dedication to delivering high-quality care establishes it as a leading option for those in need of thorough rehabilitation services within a nurturing atmosphere.

Arisa Health
Bentonville, AR

Arisa Health in Bentonville, AR, delivers thorough outpatient care for individuals of all ages struggling with substance use disorders, especially those also experiencing significant mental health conditions or emotional challenges. Their specialized outpatient services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, complemented by evidence-based therapies like anger management, brief intervention, and cognitive-behavioral therapy. A hallmark of Arisa Health is its commitment to creating personalized treatment plans designed specifically for each individual's needs. The center warmly welcomes both male and female clients, fostering a nurturing and inclusive atmosphere throughout their recovery process. Choose Arisa Health for expert support and customized treatment to begin your path to healing.

Arisa Health
Springdale, AR

Arisa Health in Springdale, AR, provides outpatient treatment for addiction and co-occurring mental health challenges affecting adults and emotional issues in children. Emphasizing personalized support, the center offers services like anger management, brief intervention, and cognitive behavioral therapy. Catering to a diverse clientele including adults, adolescents, and young adults of all genders, Arisa Health excels in outpatient care involving methadone, buprenorphine, or naltrexone. Their dedication to high-quality, holistic recovery strategies positions them as a leading provider of individualized addiction solutions.

Arisa Health
Mountain Home, AR

Arisa Health, located in Mountain Home, AR, delivers outpatient care for adults facing substance use disorders alongside significant mental health challenges, and for children experiencing severe emotional difficulties. Their specialized services encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Arisa Health emphasizes a personalized treatment model designed for adults and young individuals of any gender. Offering outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, the center is committed to a thorough and customized path to recovery. Experience dedicated support and effective rehabilitation at Arisa Health.

Arizona Counseling and Consultation

Arizona Counseling and Consultation in Columbus, OH, provides targeted treatment for substance use issues and concurrent mental health conditions affecting both adults and children. With a variety of programs including intensive outpatient, outpatient, and day treatment, the center employs proven methods such as 12-step support, brief interventions, and cognitive behavioral therapy. Customized programs are designed for active duty service members and cater to adult men and women. This facility is dedicated to delivering excellent care to help individuals of all genders achieve their recovery goals.

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Archway Recovery Services Inc, located in Fairfield, CA, delivers extensive addiction recovery programs designed for adult men. Their specialized offerings include long-term residential stays and dedicated services for individuals involved with the criminal justice system or forensic cases. The center provides continuous, round-the-clock assistance for detoxification and substance use disorder treatment. Employing therapeutic strategies like 12-step facilitation, anger management techniques, and brief intervention methods, Archway Recovery Services Inc fosters a complete path to wellness. Serving both adults and young adults, this institution is recognized for its superior treatment standards and dedication to fostering enduring sobriety within a supportive, gender-specific setting.

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Archway Recovery Services Inc in Fairfield, CA provides tailored programs for adults and young adults struggling with substance use. Their offerings include intensive outpatient, outpatient, and standard outpatient care. They utilize methods such as 12-step facilitation, anger management, and brief interventions, focusing on personalized recovery journeys. Specialized services are available for adult men and individuals involved with the criminal justice system. Archway Recovery Services Inc is equipped to support both male and female individuals, fostering an inclusive atmosphere. Their dedication to high-quality, customized treatment makes them a significant provider of recovery support.

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Situated in Clinton, IA, the Area Substance Abuse Council provides outpatient treatment options for substance use aimed at adults and older individuals. This center incorporates methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, delivering a well-rounded recovery experience. Prioritizing personalized care, the facility serves both men and women, ensuring that treatment plans are specifically designed to meet the unique needs of each person. For anyone in search of effective addiction treatment in a nurturing atmosphere, the Area Substance Abuse Council stands out as a commendable option for embarking on a path to recovery.

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Situated in New York, NY, Argus Community Inc provides intensive outpatient services as well as outpatient treatments involving methadone, buprenorphine, or naltrexone to address substance use challenges. This center emphasizes 12-step principles, anger management techniques, and short intervention strategies. It also offers specialized programs designed for individuals who have faced intimate partner violence, trauma, or who are navigating the criminal justice system. Catering to both adults and young adults from all gender identities, this facility prioritizes personalized care through tailored treatment plans. With a strong focus on high-quality, evidence-based care, Argus Community Inc is recognized as a reliable option for individuals looking for effective addiction treatment solutions.

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Argus Community Inc, located in New York, NY, delivers extensive addiction recovery programs for adults and adolescents. They excel in addressing combined substance abuse and severe mental health disorders, offering structured outpatient care, general outpatient services, and medication-assisted treatment (MAT) with methadone, buprenorphine, or naltrexone. Their therapeutic approaches include anger management, brief intervention, and cognitive behavioral therapy, serving distinct populations like current military personnel, adult males, and adult females. Customized treatment plans for each gender promote personalized recovery journeys. Argus Community Inc stands as a vital provider of effective rehabilitation solutions.

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Berryville, AR

Arisa Health located in Berryville, AR, provides targeted outpatient services for adults grappling with substance use issues and concurrent severe mental health disorders, as well as for children and adolescents facing significant emotional challenges. Emphasizing personalized treatment, the center includes programs such as anger management, brief intervention, and cognitive behavioral therapy. Additionally, Arisa Health offers outpatient services for methadone/buprenorphine or naltrexone. The facility serves both men and women, focusing on customized care to meet each person's specific requirements. With a dedication to delivering high-quality support, Arisa Health is distinguished by its all-encompassing programs aimed at promoting recovery and enhancing overall health.

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Harrison, AR

Situated in Harrison, AR, Arisa Health delivers targeted outpatient services for individuals dealing with substance use and co-occurring mental health issues, catering to both adults and younger populations. The center employs a variety of methodologies, such as anger management techniques, cognitive behavioral therapy, and short-term interventions. With an emphasis on customized treatment, Arisa Health adapts its programs to accommodate the specific requirements of every client. The facility provides outpatient options for methadone, buprenorphine, or naltrexone therapy, ensuring high-quality care for male and female patients alike. If you or someone you care about is in search of thorough and individualized support for addiction, Arisa Health is dedicated to aiding you along your path to recovery.

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Huntsville, AR

Situated in Huntsville, Arkansas, Arisa Health delivers expert outpatient care for individuals of all ages struggling with addiction and co-occurring mental health challenges. Their services encompass various treatment modalities, such as medication-assisted treatment (methadone/buprenorphine or naltrexone), standard outpatient programs, and custom care strategies. Arisa Health employs a holistic approach to recovery, emphasizing anger management techniques, brief intervention strategies, and cognitive behavioral therapy. They offer distinct programs for male and female clients, ensuring personalized and impactful support. Arisa Health is your partner in achieving lasting wellness and recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)