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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Arkview Recovery Center
Mechanicsburg, PA

Arkview Recovery Center, located in Mechanicsburg, PA, specializes in providing extensive addiction recovery services for both adults and young adults. The facility offers a range of services including detoxification, treatment for substance use issues, and targeted support for those dealing with co-occurring mental health disorders. Treatment options available at Arkview consist of intensive outpatient programs, outpatient services, and day treatment sessions. Emphasizing techniques such as 12-step support, anger management, and cognitive behavioral therapy, the center customizes its programs to address the unique requirements of each individual. Additionally, tailored programs are available for adult men, adult women, and clients with trauma backgrounds. Arkview Recovery Center is committed to delivering high-quality care to all individuals, regardless of their gender, employing a compassionate and evidence-based methodology in its rehabilitation efforts.

Arlington Recovery Center

Arlington Recovery Center, situated in Arlington, VA, delivers extensive treatment for individuals of all ages facing addiction and concurrent mental health challenges. Their services include extended residential stays, on-site detox, and continuous care within a nurturing atmosphere. The center features distinct programs for adult men, adult women, and those with trauma histories, ensuring personalized treatment plans. Employing proven methods such as 12-step guidance, emotional regulation techniques, and short-term counseling, they guarantee high standards of care. This institution is open to all individuals, regardless of gender, who are pursuing sobriety and well-being.

Armada Recovery of PA
King of Prussia, PA

Armada Recovery of PA in King of Prussia provides a spectrum of outpatient care, including intensive outpatient, standard outpatient, and day treatment, specifically for individuals struggling with substance use disorders. Their therapeutic approach incorporates proven methods like 12-step facilitation, anger management techniques, and brief intervention strategies. Serving adults and young adults of any gender, Armada Recovery of PA prides itself on creating treatment plans that are carefully customized to meet the distinct requirements of each person. The center is dedicated to offering exceptional support for those pursuing a path to lasting sobriety. For those in search of expert substance use treatment designed around their individual circumstances, Armada Recovery of PA stands as a commendable option.

ARS of Aberdeen
Aberdeen, MD

Situated in Aberdeen, MD, ARS of Aberdeen specializes in extensive treatment for substance use disorders targeting both adults and young adults. The center provides various levels of care including intensive outpatient programs, regular outpatient services, and treatments that utilize methadone/buprenorphine or naltrexone. Implementing research-backed methods such as cognitive behavioral therapy, motivational incentives, and the Matrix Model, ARS of Aberdeen serves both men and women, as well as individuals facing co-occurring mental health and substance use challenges. With tailored programs designed for diverse populations and a commitment to high-quality treatment, ARS of Aberdeen is focused on aiding individuals in their recovery journey.

ARS of Aberdeen LLC

ARS of Aberdeen LLC in Aberdeen, MD, provides a full spectrum of substance abuse treatment, including intensive outpatient, standard outpatient, and medication-assisted treatment options with methadone, buprenorphine, or naltrexone. Their therapeutic approach integrates cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, all delivered within a personalized framework designed to meet individual needs. The center welcomes adults and young adults of all genders, offering tailored support for a wide range of recovery journeys. ARS of Aberdeen LLC is dedicated to delivering high-quality, evidence-based care in a nurturing setting for individuals pursuing recovery. Discover individualized support and proven rehabilitation strategies at this location.

ARS New Castle
New Castle, DE

ARS New Castle, located in New Castle, DE, specializes in a wide range of substance use treatment and provides particular attention to adults facing both substance use disorders and significant mental health challenges, as well as addressing emotional issues in children. The center offers various treatment formats, including intensive outpatient care, outpatient programs, and options involving methadone, buprenorphine, or naltrexone. Utilizing research-backed methods like cognitive behavioral therapy and contingency management, ARS New Castle tailors its services to meet the unique needs of active duty military members and both men and women. With a focus on delivering exceptional care, the facility is recognized for its array of treatment options and personalized recovery paths.

Aroostook Mental Health Center

Aroostook Mental Health Center in Ellsworth, ME, provides extensive addiction treatment for adults facing concurrent serious mental health conditions. This center focuses on outpatient programs, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, supporting those in need of ongoing care. Employing proven strategies like anger management, brief intervention, and cognitive behavioral therapy, the center delivers personalized treatment for adult males, young people, and active military members. Their diverse programs are available for all genders and age ranges, including older adults, ensuring robust assistance for individuals working towards recovery from substance abuse and mental health issues.

Arms Acres Inc
Jamaica, NY

Arms Acres Inc in Jamaica, NY, provides targeted interventions for individuals grappling with substance use disorders. Their service offerings include comprehensive intensive outpatient programs, flexible outpatient services, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing therapeutic modalities like anger management, cognitive behavioral therapy, and motivational interviewing, Arms Acres Inc serves a diverse clientele including adolescents, adult men, and adult women. The center is dedicated to supporting individuals of all ages and genders on their path to recovery. Prioritizing personalized treatment plans and proven therapeutic methods, Arms Acres Inc delivers exceptional care to those pursuing a life free from addiction.

Arrowhead Behavioral Health

Arrowhead Behavioral Health, located in Maumee, OH, provides a holistic approach to the treatment of detoxification, substance abuse, and co-occurring mental health disorders for both adults and children. The center features inpatient detox services, employing proven methods such as 12-step programs, cognitive behavioral therapy, and the Matrix Model for effective treatment. Tailored programs designed for active military personnel, as well as for adult males and females, allow Arrowhead Behavioral Health to serve a variety of communities. Individuals can anticipate personalized and high-standard care within a nurturing atmosphere at this rehabilitation center.

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Arlington County Community Servs Board, located in Arlington, VA, provides a wide range of substance abuse treatment options for adults who also face significant mental health challenges. This center features programs for intensive outpatient care, general outpatient services, and medication-assisted treatments including methadone, buprenorphine, and naltrexone. It has specialized initiatives for active military members, teenagers, and adult males, accommodating various groups. The center employs methods such as 12-step support, anger management, and brief therapeutic interventions to customize their care. Supporting adults and seniors of all genders, this facility is dedicated to offering effective, research-backed treatment for those on their journey to overcome addiction and related disorders.

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Carmel, NY

Arms Acres Inc, located in Carmel, NY, delivers dedicated programs for the treatment of substance use disorders. This center specializes in intensive outpatient treatment, standard outpatient services, and options utilizing methadone, buprenorphine, or naltrexone. Arms Acres Inc emphasizes anger management, brief interventions, and cognitive behavioral therapies, customizing its methods to address the unique requirements of each client. The facility is distinguished by its focused programs catering to adolescents, adult males, and adult females. It serves a diverse clientele, including both adults and children/adolescents, accommodating individuals of all genders. Arms Acres Inc is committed to providing high-quality care and individualized treatment strategies to aid individuals in their recovery journey.

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Carmel, NY

Arms Acres Inc, located in Carmel, NY, provides a full spectrum of care for individuals struggling with substance use disorders. Their offerings encompass intensive outpatient services, general outpatient programs, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Treatment modalities utilized include anger management techniques, brief intervention strategies, and cognitive behavioral therapy. The center also features distinct programs tailored for adult men, adult women, and those affected by intimate partner or domestic violence. Catering to adults and young adults of all genders, Arms Acres Inc is dedicated to delivering high-quality, personalized treatment plans designed to foster lasting recovery from addiction.

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Situated in Kittanning, PA, the Armstrong County Council on Alc presents a variety of treatment options for substance use issues. This center offers intensive outpatient services, long-term residential treatment, and outpatient care specifically for adults and seniors. Emphasizing 12-step methods, brief interventions, and cognitive behavioral therapy, it serves both male and female clients. Additionally, specialized programs are available for adolescents, women, and those who have faced trauma, allowing for personalized care that addresses different requirements. Dedicated to delivering high-quality care grounded in evidence-based practices, this facility offers extensive support for individuals on their journey to recovery from substance use disorders.

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Nestled in Caribou, ME, Aroostook Mental Health Center delivers expert treatment for substance abuse and dual diagnoses to individuals of all ages. Through structured intensive outpatient and outpatient services, they employ proven therapeutic methods including cognitive behavioral therapy and anger management. Their adaptable programs are designed for teenagers, adult men, and women, ensuring personalized support. Aroostook Mental Health Center is dedicated to providing exceptional care and thorough assistance to adults and seniors, regardless of gender, who are striving to conquer addiction and mental health issues.

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Aroostook Mental Health Center located in Calais, ME, specializes in treating substance use disorders alongside severe mental health conditions or emotional challenges. The center features a variety of services, including intensive outpatient programs, standard outpatient care, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing methods like anger management, brief interventions, and cognitive behavioral therapy, Aroostook adapts its services to fit the unique needs of each client. Additionally, there are dedicated programs designed for active military members, teens, and adult males. This center is committed to providing high-quality support to adults and seniors of all genders, ensuring a wide array of services aimed at fostering sustainable recovery.

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Aroostook Mental Health Center located in Madawaska, ME, provides a wide range of substance abuse treatments designed for adults facing serious mental health challenges alongside children experiencing significant emotional issues. The center's offerings encompass intensive outpatient programs, general outpatient services, and medications such as methadone, buprenorphine, or naltrexone for outpatient care. Utilizing methods such as anger management, short interventions, and cognitive behavioral therapy, the center serves active duty military personnel, teenagers, adult males and females, and seniors. With a focus on personalized care, this facility delivers high-standard rehabilitation solutions tailored to meet the needs of individuals seeking assistance with addiction and mental health matters.

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Situated in Presque Isle, ME, the Aroostook Mental Health Center delivers targeted rehabilitation services for individuals dealing with substance abuse challenges alongside mental health conditions. The center provides a variety of treatment options, including intensive outpatient programs, regular outpatient services, and medication-assisted treatments using methadone, buprenorphine, or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, the facility serves both adults and seniors, and offers specialized programs for active military personnel, adolescents, and adult males. Committed to offering customized care for both men and women, this center prioritizes a thorough and high-quality approach to support those on their path to recovery and wellness.

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Aroostook Mental Health Center, situated in Houlton, ME, specializes in a wide range of substance use therapies for both children and adults grappling with concurrent mental health issues. This facility offers intensive outpatient services alongside outpatient treatment options that include methadone, buprenorphine, or naltrexone. Emphasizing approaches such as anger management, cognitive behavioral therapy, and concise intervention methods, the center supports military personnel, teenagers, and adult males. Catering to both men and women, including seniors, Aroostook Mental Health Center is committed to providing personalized care, establishing itself as a reliable option for individuals pursuing successful rehabilitation outcomes in the area.

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Aroostook Mental Health Center, located in Presque Isle, ME, specializes in comprehensive treatment for substance use disorders in both adults and young adults who also face significant mental health challenges or emotional issues. The center offers both residential and short-term residential services customized to meet the specific needs of clients. With programs designed for active duty military members as well as distinct services for adult men and women, this facility prioritizes individualized support. Employing evidence-based techniques such as 12-step programs, anger management, and brief interventions, the center aims for a holistic approach to recovery. Aroostook Mental Health Center serves a diverse clientele, committed to delivering exceptional care and assistance to help individuals attain sustained sobriety and improved mental health.

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Aroostook Mental Health Center in Machias, ME, is dedicated to providing comprehensive care for individuals of all ages struggling with addiction and related mental health conditions. They offer a range of therapeutic approaches, including intensive outpatient services, general outpatient care, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their therapeutic framework includes specialized interventions such as anger management, brief counseling, and cognitive behavioral therapy, serving a diverse clientele that includes adults, seniors, active military personnel, teenagers, and adult men. The center is equipped to support both men and women, ensuring personalized treatment plans designed for successful and sustained recovery.

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Aroostook Mental Health Center, situated in Fort Kent, ME, offers complete care for substance use disorders. They are particularly adept at treating individuals with co-occurring substance use issues and significant mental health challenges, serving both adults and young people. The center provides a range of treatment options, including intensive outpatient, outpatient, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Their therapeutic methods encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Special services are available for active-duty military personnel, teenagers, and adult men. Aroostook Mental Health Center's commitment to individualized care and effective treatment makes it a dependable choice for comprehensive recovery services for adults and seniors of all genders.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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