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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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ARS of Ephrata
Ephrata, PA

Situated in Ephrata, Pennsylvania, ARS of Ephrata delivers extensive treatment for substance use through outpatient services and medication-assisted options such as methadone, buprenorphine, or naltrexone. The center focuses on remedies for anger management, provides brief interventions, and employs cognitive behavioral therapy. It offers distinct programs designed for those affected by trauma, members of the LGBTQ community, as well as expectant and new mothers. Catering to adults and young adults of all identities, ARS of Ephrata ensures high-quality support in a nurturing atmosphere. If you or someone you care about is in need of substance use assistance featuring specialized programs and proven methodologies, this center is well-prepared to aid in the recovery process.

Asana Recovery
Costa Mesa, CA

Asana Recovery, situated in Costa Mesa, California, delivers extensive addiction treatment options for both adults and young adults. The center features long-term residential programs, detoxification services, and round-the-clock support. Prioritizing 12-step methodologies, anger management techniques, and cognitive behavioral therapy, Asana Recovery customizes its services to cater to the unique needs of each individual. The facility is proficient in addressing co-occurring substance use disorders along with significant mental health conditions in adults, and it also caters to serious emotional challenges in children. With a strong emphasis on personalized care, Asana Recovery ensures quality treatment for male and female clients aiming to overcome addiction.

Asana Recovery
Huntington Beach, CA

In Huntington Beach, California, Asana Recovery provides extensive substance abuse treatment for adults and young adults. This establishment offers extended stays in residence, detox services while residing on-site, and round-the-clock residential care for those confronting substance dependence and concurrent significant mental health challenges. Asana Recovery utilizes proven therapeutic methods including 12-step program support, emotional regulation training, and cognitive-behavioral techniques. A key feature of this center is its custom treatment strategies designed for each person's unique circumstances. Featuring distinct offerings for males and females, Asana Recovery is committed to delivering excellent support for individuals embarking on their journey to wellness.

Asana Recovery Center
Costa Mesa, CA

Asana Recovery Center, located in Costa Mesa, CA, delivers a wide array of addiction treatment options tailored for both adults and young adults. This center features long-term residential treatment, detox services, and round-the-clock care. It is particularly adept at addressing co-occurring substance use disorders alongside severe mental health issues in adults and significant emotional challenges in children. Emphasizing personalized treatment plans, Asana Recovery Center employs various methods such as 12-step programs, anger management techniques, and cognitive behavioral therapy. The center is designed to accommodate both men and women, fostering a welcoming and inclusive atmosphere for all individuals pursuing recovery.

Ascend Clinical Services

Ascend Clinical Services, located in Rehrersburg, PA, specializes in a wide range of addiction treatment options for both adults and young adults. The facility offers services such as detox, intensive outpatient programs, and outpatient treatments involving methadone, buprenorphine, or naltrexone. By employing techniques like 12-step facilitation, brief intervention, and cognitive behavioral therapy, Ascend Clinical Services addresses the needs of men and women dealing with both mental health issues and substance use disorders. Committed to delivering high-quality care, the center customizes treatment plans to suit each individual's needs. It provides a nurturing atmosphere for both male and female clients seeking to overcome their substance use challenges.

Ascend Healthcare

Ascend Healthcare in Encino, CA, provides dedicated recovery programs for individuals struggling with addiction and underlying mental health conditions. Their services are structured to support adults with substance use and co-occurring disorders, as well as children experiencing emotional difficulties. Clients can choose from various care settings, including hospital-level inpatient treatment, continuous 24-hour support, and extended residential stays. The center employs personalized therapeutic strategies like 12-step integration, anger management techniques, and brief intervention methods. Ascend Healthcare distinguishes itself by offering specialized care for adolescents, survivors of domestic violence, and those who have endured sexual trauma. Serving men, women, and young people, the facility is committed to delivering thorough and empathetic assistance to all who are on their journey to wellness.

Ascendant New York
New York, NY

Ascendant New York, located in New York, NY, provides a full range of services for addiction recovery, including detox and therapies for substance abuse. The center features 24/7 residential care and various short-term residential options, creating a nurturing space for individuals seeking to recover. Using techniques such as 12-step programs, anger management, and cognitive behavioral strategies, the treatment plans are customized to meet the unique needs of each person. Ascendant New York caters to adults and young adults of all genders, emphasizing a tailored approach and a commitment to delivering high-quality care aimed at helping individuals attain enduring sobriety.

Ascendant NY
New York, NY

Ascendant NY, located in New York, NY, provides focused substance use rehabilitation via its residential programs. Prioritizing 12-step strategies, anger management techniques, and cognitive behavioral therapy, this facility caters to both adults and young adults with customized treatment plans. With an emphasis on personalized care, Ascendant NY delivers quality support for clients of all genders. The center offers both short-term and round-the-clock residential care, ensuring immersive assistance in a well-organized setting. By integrating proven methodologies with individualized attention, Ascendant NY distinguishes itself as a thorough rehabilitation center committed to aiding individuals in their journey to recovery from addiction.

ARS Of Lancaster LP
Lancaster, PA

ARS Of Lancaster LP, located in Lancaster, PA, provides a wide range of addiction rehabilitation services for both adults and young adults. The center focuses on detoxification and treatment for substance use, offering intensive outpatient and standard outpatient programs, inclusive of outpatient detox services. ARS Of Lancaster LP employs evidence-based methods like cognitive behavioral therapy and contingency management, customizing treatment plans to meet the unique needs of each individual. With specialized programs available for active duty military personnel, adult men, and adult women, the center is committed to delivering tailored care. Serving clients of all genders, ARS Of Lancaster LP is dedicated to facilitating recovery journeys with high-quality support.

ASCEND Csl and Recovery Services

ASCEND Csl and Recovery Services located in Portsmouth, OH, provides comprehensive treatment for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. The center offers a variety of services including intensive outpatient programs, outpatient care, and day treatment, employing tailored strategies such as 12-step facilitation, anger management, and cognitive behavioral therapy. Distinct programs are available for adult men, adult women, and those who have faced trauma. This facility is dedicated to serving individuals of all genders, including seniors, and emphasizes personalized care to facilitate clients' journeys toward recovery.

Arvada Counseling Center Inc

Arvada Counseling Center Inc, located in Arvada, CO, specializes in the treatment of substance use issues for individuals ranging from adults to young adults and adolescents. The facility offers a variety of programs including intensive outpatient, outpatient, and standard outpatient options. Emphasizing methods such as anger management, cognitive behavioral therapy, and community reinforcement with vouchers, the center customizes its approach to meet the specific needs of each client. Unique offerings are available for active duty military members, adolescents, and adult men. Catering to both women and men, Arvada Counseling Center Inc provides a holistic and thorough rehabilitation experience, ensuring clients receive high-quality and individualized support throughout their recovery journey.

Arthur Center Community Health

The Arthur Center Community Health, situated in Montgomery City, MO, provides extensive outpatient care for adults and seniors battling substance use disorders. This center offers personalized programs in a nurturing setting for both men and women on their journey to recovery. Their treatment model integrates outpatient medication-assisted treatment, including methadone, buprenorphine, or naltrexone, with ongoing outpatient services, promoting a complete and successful recovery. The Arthur Center Community Health is recognized for its high standards of care and tailored strategies, making it a dependable option for individuals aiming to conquer addiction and rebuild their lives.

ARTS Potomac Street Center

Nestled in Aurora, Colorado, the ARTS Potomac Street Center delivers complete care for individuals struggling with substance use disorders, serving both adults and younger adults. Their offerings include intensive outpatient, standard outpatient, and medication-assisted treatment options using methadone, buprenorphine, or naltrexone. Addressing key areas such as anger management, brief interventions, and cognitive behavioral therapy, the center is equipped to support adult men and women, as well as those who have faced trauma. Tailored programs are a hallmark, ensuring each person receives personalized support. The ARTS Potomac Street Center is committed to high standards and proven methods, guiding individuals toward lasting recovery.

Ascensa Health
Atlanta, GA

Situated in Atlanta, GA, Ascensa Health specializes in long-term residential rehabilitation for adults facing substance abuse and serious mental health disorders. This facility is particularly attentive to the needs of adult women, including those who have experienced intimate partner violence, domestic abuse, and sexual trauma. Ascensa Health emphasizes approaches such as 12-step facilitation, anger management, and brief interventions, serving female adults, seniors, and young adults in their pursuit of thorough and empathetic rehabilitation solutions. The center’s commitment to personalized treatment and exceptional care positions it as a leading option for individuals seeking specialized assistance for their substance use and mental health challenges.

Ascensa Health
Atlanta, GA

Situated in Atlanta, GA, Ascensa Health is a dedicated rehabilitation facility that provides extended residential and around-the-clock support for adult males in need of substance use treatment. The center emphasizes customized care, employing proven methodologies such as 12-step programs, cognitive behavioral therapy, and contingency management. Notably, Ascensa Health prioritizes the unique needs of clients who have faced intimate partner violence, domestic violence, and sexual trauma. Designed for adult men, including seniors and young adults, this center fosters a secure and nurturing atmosphere. With a strong focus on delivering high-quality care, Ascensa Health has established itself as a reliable option for those seeking thorough and impactful rehabilitation services.

Ascensa Health
Atlanta, GA

Ascensa Health in Atlanta, GA, delivers a full spectrum of addiction recovery solutions, encompassing medically supervised detox and ongoing treatment for substance dependence. The center features tailored programs designed for adult men, adult women, and individuals who have faced domestic abuse, ensuring personalized support for each client's unique circumstances. Employing evidence-based strategies like 12-step integration, cognitive behavioral techniques, and relapse prevention planning, Ascensa Health facilitates a complete and successful healing process. Their offerings include extended residential stays, detox in a residential setting, and round-the-clock residential care, available to adults and young adults of any gender. Discover exceptional care and encouragement at Ascensa Health as you embark on your path to lasting sobriety.

Ascensa Health
Atlanta, GA

Ascensa Health, located in Atlanta, GA, provides extensive treatment for substance use, specifically designed for women, seniors, and young adults. This center excels in long-term and around-the-clock residential care, offering personalized attention through research-backed methods like 12-step programs, cognitive behavioral therapy, and contingency management. Distinctive initiatives are available for adult women, as well as individuals healing from intimate partner violence, domestic abuse, and sexual trauma. Committed to high-quality, individualized care, Ascensa Health strives to support clients in attaining sustainable recovery.

Ascend Recovery
American Fork, UT

Ascend Recovery, located in American Fork, UT, delivers a complete spectrum of care for adults and adolescents struggling with addiction and coexisting mental health concerns. Their offerings include intensive outpatient, extended residential, and outpatient services, all grounded in proven therapeutic methods like 12-step facilitation, anger management, and brief intervention. Tailored programs are available for adult men and women, as well as individuals with a history of sexual abuse. Ascend Recovery prioritizes personalized treatment plans within a nurturing setting for all clients on their journey to wellness.

Ascend Recovery
American Fork, UT

Ascend Recovery, located in American Fork, UT, delivers extensive treatment solutions for adults and young adults grappling with substance abuse and related mental health conditions. Their specialized care extends to those with histories of sexual trauma, offering intensive outpatient, extended residential stays, and regular outpatient therapy. Employing methods like 12-step integration, emotional regulation techniques, and short-term counseling, Ascend Recovery serves all genders. The facility prioritizes personalized care and targeted programs for adult men, adult women, and distinct age demographics, guaranteeing effective treatment designed for individual requirements.

Ascend Recovery
Salt Lake City, UT

Ascend Recovery in Salt Lake City, UT, delivers a complete spectrum of healing programs. The facility offers intensive outpatient, day treatment, and partial hospitalization for adults and young adults facing addiction and co-occurring psychological health challenges. Emphasizing 12-step principles, emotional regulation techniques, and brief counseling, this establishment serves adult men and women, along with individuals with a history of sexual trauma. Providing options for transitional living and sober residences, Ascend Recovery cultivates a nurturing atmosphere for those embarking on their healing journey. Featuring tailored initiatives for various age brackets and sexes, the center provides excellent support to address varied requirements.

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Situated in Fulton, MO, the Arthur Center Behavioral Health delivers targeted outpatient treatment for substance use disorders among adults and seniors. Emphasizing personalized care, the center offers treatments including outpatient methadone/buprenorphine or naltrexone options, regular outpatient services, and customized programs designed for individual needs. The facility employs various methods such as 12-step facilitation, anger management, and brief interventions to provide thorough care for all clients, regardless of gender. Patients can look forward to receiving exceptional treatment within a nurturing environment that fosters long-term recovery. For those in search of effective addiction recovery solutions with a customized approach, the Arthur Center Behavioral Health is an ideal choice.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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