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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Ascension
Milwaukee, WI

Ascension, located in Milwaukee, WI, delivers an extensive array of treatment options for both adults and young adults dealing with substance use issues and associated mental health disorders. This center features hospital-based inpatient detox programs and treatment services, including targeted care for those grappling with severe mental health conditions or emotional issues. By emphasizing 12-step support, anger management techniques, and short interventions, Ascension customizes its services to cater to the specific needs of each individual. The center incorporates specialized programs for adult men, women, and individuals with dual diagnoses to provide focused and effective treatment. Committed to delivering high-quality care, this facility supports both male and female clients on their journey to recovery and wellness.

Ascension Eastwood Behavioral Health

Ascension Eastwood Behavioral Health, located in Southfield, MI, delivers specialized services for those in need of detox and treatment for substance use disorders. The facility offers customized treatment plans for adults grappling with both substance use disorders and significant mental health issues, as well as for children experiencing severe emotional difficulties. With options including residential detox, continuous residential care, and short-term stays, the center provides 24/7 assistance to its clients. Employing methods like 12-step programs, cognitive behavioral therapy, and brief interventions, it emphasizes personalized care. Ascension Eastwood Behavioral Health serves a diverse range of individuals, including adult men, seniors, and young adults, ensuring excellent treatment that supports sustainable recovery with a focus on individualized attention.

Ascension Saint Vincent

Ascension Saint Vincent, located in Anderson, IN, provides a wide range of services for those seeking help with addiction. Catering to adults and older individuals, this center features inpatient detoxification and treatment specifically for substance use disorders, along with any accompanying mental health issues. The facility has unique programs designed for different demographics, including adolescents, men, and women. Utilizing methods such as 12-step support, anger management strategies, and concise interventions, Ascension Saint Vincent prioritizes personalized treatment. Both male and female clients benefit from specialized assistance in a nurturing environment. Committed to high standards of care, this center aims to support individuals on their journey to sustained recovery.

Asheville Comprehensive Treatment Ctr

Asheville Comprehensive Treatment Ctr located in Asheville, NC, specializes in outpatient care for individuals struggling with substance use issues, including both adults and young adults. The center offers programs incorporating methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Its methodology is rooted in evidence-based practices, integrating techniques such as brief interventions, cognitive behavioral therapy, and motivational incentives. The facility also includes specialized programs for clients involved in the criminal justice system and for women who are pregnant or in the postpartum phase. Committed to personalized care, this center supports male and female clients alike, fostering a nurturing and inclusive atmosphere for those pursuing recovery from addiction.

Asheville Recovery Center

Asheville Recovery Center, situated in Asheville, North Carolina, provides thorough treatment for substance use disorders aimed at both adults and young adults. The center offers a variety of programs including intensive outpatient, outpatient, and standard outpatient options. It employs techniques such as 12-step support, brief interventions, and cognitive behavioral therapy to create personalized treatment plans. Programs are specifically designed for adult men, adult women, and young adults. With an emphasis on high-quality care, Asheville Recovery Center ensures gender-specific services for both men and women. Those in search of effective addiction recovery in a nurturing environment will find a dedicated commitment to fostering long-term healing at this facility.

Ashley Inc
Bel Air, MD

Situated in Bel Air, Maryland, Ashley Inc provides extensive addiction recovery solutions for adults and adolescents. The center excels in detox and substance abuse treatment, delivering intensive outpatient, outpatient, and day treatment options. Emphasizing 12-step facilitation, anger control, and brief intervention strategies, Ashley Inc customizes its offerings to suit each person's distinct requirements. Distinctive services include targeted programs for individuals involved with the criminal justice system. Catering to both men and women, this establishment guarantees excellent care and assistance for individuals on their journey to overcome addiction.

Ashley Inc
Havre de Grace, MD

Situated in Havre de Grace, MD, Ashley Inc delivers a complete spectrum of substance use disorder treatment for individuals of all ages. The facility focuses on medically supervised withdrawal, therapeutic interventions for addiction, and the management of dual diagnoses. Patients receive inpatient hospital care emphasizing 12-step principles, emotional regulation skills, and short-term therapeutic strategies. Tailored programs are available for adult men, women, and survivors of domestic abuse. Ashley Inc is dedicated to personalized treatment plans for all clients, male and female, aiming for lasting recovery from addiction and emotional health issues.

Ashwood Recovery

Ashwood Recovery, situated in Boise, ID, provides extensive care for individuals battling addiction. This facility focuses on adults and young adults, with a particular emphasis on addressing dual diagnoses, including mental health challenges in adults and emotional issues in children alongside substance dependence. Their treatment modalities encompass intensive outpatient, outpatient services, and partial hospitalization. Ashwood Recovery employs scientifically-backed methods like 12-step support, emotional regulation techniques, and concise therapeutic interventions. They also offer distinct programs for those experiencing both chronic pain and addiction. Recognizing the importance of individualized support, the center offers gender-specific services, ensuring that recovery plans are customized for optimal results and a comprehensive approach to wellness.

Asian American Chemical Dependency

Situated in Lakewood, WA, the Asian American Chemical Dependency center delivers extensive treatment for substance use disorders in both adults and children who also face mental health challenges. The center offers a variety of programs, including intensive outpatient and standard outpatient treatments, employing techniques like 12-step education, anger management sessions, and brief intervention strategies. The center serves active duty military members, teenagers, and adult males, providing services for all genders. Committed to excellence in care and personalized treatment plans, this center strives to support individuals on their journey to overcome addiction and attain sustainable recovery.

Asian American Drug Abuse Program

The Asian American Drug Abuse Program, situated in Los Angeles, CA, delivers extended residential treatment for adults grappling with substance use disorders. This establishment furnishes options for clients pursuing thorough rehabilitation, including transitional living, halfway housing, and sober living accommodations. Employing therapeutic methodologies such as 12-step program integration, emotional regulation techniques, and cognitive behavioral interventions, this program serves adults and young adults, with particular attention to those impacted by trauma. Prioritizing excellent care and personalized treatment plans, the center cultivates a nurturing setting for individuals aiming to conquer addiction and attain enduring sobriety.

Asian Counseling and Referral Service

Situated in Seattle, WA, the Asian Counseling and Referral Service delivers tailored care for substance use disorders and co-occurring issues affecting both adults and children. The center offers various outpatient treatment alternatives, including intensive programs, fostering a nurturing atmosphere for those on their recovery journey. By employing research-backed methods such as cognitive behavioral therapy and 12-step participation, the facility serves a wide array of communities, encompassing teenagers and distinct gender demographics. Committed to high-quality care and personalized treatment strategies, this center aims to assist both adults and youth in overcoming addiction and mental health obstacles.

Asian Family Services

Asian Family Services in Hartford, CT, provides thorough substance abuse therapies. They offer particular support for those with co-occurring severe mental health challenges or emotional problems. Their intensive outpatient and standard outpatient services include 12-step group support, emotional regulation training, and short-term counseling. Distinctive programs are available for adult men and women, along with individuals who have faced domestic abuse. Serving adults and young adults of all genders, the center focuses on delivering excellent care. For anyone looking for addiction treatment in a nurturing setting designed for individual requirements, Asian Family Services could be a suitable option.

Ascension Brighton Center for Recovery

Ascension Brighton Center for Recovery in Brighton, MI, provides extensive substance abuse treatment for adults and adolescents. Services include medically supervised detox and inpatient care, complemented by transitional living arrangements. Emphasizing 12-step integration, emotional regulation, and cognitive restructuring, the center addresses individuals facing concurrent mental health and addiction challenges. Both men and women are accepted, fostering a nurturing and welcoming atmosphere. Ascension Brighton Center for Recovery is committed to offering superior treatment and tailored plans to guide individuals toward lasting sobriety.

Ashley Addiction Treatment

Ashley Addiction Treatment, situated in Elkton, MD, delivers a full spectrum of care for those pursuing freedom from addiction. Their offerings include medically supervised detoxification and robust outpatient therapy, employing proven methods like 12-step integration, cognitive behavioral therapy, and emotional regulation training. Ashley distinguishes itself with tailored programs designed for adult men, adult women, and individuals impacted by domestic abuse, reflecting a commitment to serving a varied clientele. Both adult and adolescent patients have access to outpatient services and partial hospitalization programs. The center's dedication to personalized treatment plans and therapies backed by research guarantees exceptional support for everyone in their care.

Ascensa Health
Atlanta, GA

Ascensa Health, located in Atlanta, GA, provides a wide range of substance use rehabilitation services, including intensive outpatient programs, daytime outpatient treatment, and partial hospitalization options for both adults and young adults. The center specializes in various therapeutic approaches such as 12-step facilitation, cognitive behavioral therapy, and contingency management, offering customized support for both men and women, including those coping with intimate partner or domestic violence experiences. By emphasizing gender-specific requirements, Ascensa Health is dedicated to delivering effective care and assistance for individuals on their path to recovery from addiction.

Ascension All Saints

Ascension All Saints in Racine, WI, delivers exceptional rehabilitation care. They provide inpatient medical detoxification and comprehensive treatment for substance use disorders, alongside specialized programs for adults with co-occurring mental health conditions and children experiencing emotional difficulties. Their approach incorporates evidence-based therapies such as anger management, brief intervention, and cognitive behavioral therapy. The center features distinct programs designed for adult men, women, and individuals who have endured trauma. Their services are inclusive, catering to adults and seniors across all genders. Ascension All Saints is recognized for its thorough treatment plans and empathetic support for those pursuing healing from addiction and mental health concerns.

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Ascension Behavioral Health, situated in Chicago, IL, delivers thorough addiction recovery solutions for adults and young adults. This facility features intensive outpatient, outpatient, and partial hospitalization program (day treatment) options. Their expertise encompasses 12-step facilitation, anger management, and cognitive behavioral therapy. Ascension Behavioral Health serves adult men and women, including those with trauma histories. Committed to personalized care, they provide excellent services adjusted to individual client requirements. Male and female individuals searching for successful addiction treatment in a nurturing setting will discover specialized support at this respected recovery center.

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Ascension Illinois Presence Behavioral located in Palos Heights, IL, provides targeted treatment programs for substance use, serving both adults and teenagers. This facility offers intensive outpatient therapy, standard outpatient services, as well as outpatient treatment options involving methadone, buprenorphine, or naltrexone. Emphasizing 12-step facilitation, anger management techniques, and cognitive behavioral therapy, the center prioritizes personalized and thorough care. A standout feature is its specialized program for adolescents, catering to their distinct requirements in a nurturing setting. The center welcomes clients of all genders, ensuring high-quality, individualized support throughout their recovery journey.

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Ascension Illinois Presence Behavioral in Westchester, IL, is dedicated to assisting adults and young adults who are navigating the challenges of substance abuse and coexisting mental health disorders. The facility offers robust intensive outpatient and outpatient treatment tracks, incorporating medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Employing scientifically validated methods like 12-step facilitation, anger management techniques, and brief intervention strategies, Ascension Illinois Presence Behavioral serves a diverse clientele, accommodating both men and women. A particular emphasis is placed on supporting individuals involved in the criminal justice and forensic systems, ensuring a holistic recovery journey within a nurturing setting. The center's dedication to high standards and personalized care plans positions Ascension Illinois Presence Behavioral as a significant provider of addiction recovery services.

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Ascension Saint Mary Hospital located in Bourbonnais, IL, specializes in extensive substance use rehabilitation through its range of programs, including intensive outpatient, outpatient, and standard outpatient services. The center employs strategies like 12-step facilitation, anger management, and brief intervention to ensure personalized treatment for both adults and children/adolescents. Emphasizing a tailored approach, this facility serves both men and women in need of effective addiction recovery solutions. Ascension Saint Mary Hospital of Bourbonnais is committed to providing exceptional care to aid individuals in their recovery process.

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Ashby Behavioral Health LLC, located in Quincy, MA, provides a wide range of services for substance use disorders and also addresses significant mental health challenges in adults and emotional issues in children. The facility delivers intensive outpatient programs, general outpatient services, and day treatment alternatives. Utilizing customized strategies such as 12-step support, anger management techniques, and brief interventions, they serve both adult and young adult populations of all genders. Additionally, programs specifically designed for active duty military personnel, as well as separate services for adult men and women, ensure personalized attention. Ashby Behavioral Health LLC is committed to offering high-quality, evidence-based care to assist individuals on their path to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)