NWVCIL Logo
Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6711 results

Asociacion Puertorriquenos en Marcha

Asociacion Puertorriquenos en Marcha is situated in Philadelphia, PA, providing a range of outpatient services including detoxification and treatment for substance use disorders. The center also addresses co-occurring conditions affecting adults and emotional challenges in children. It has a strong emphasis on techniques such as 12-step facilitation, anger management, and short-term intervention strategies, catering to active military personnel, teenagers, and adult males. By offering support for individuals of all genders, this facility aims to deliver personalized care for those striving for recovery from addiction. Dedicated to providing high-quality services, Asociacion Puertorriquenos en Marcha stands as a pillar of support for individuals on their healing journey.

AspenRidge Recovery

AspenRidge Recovery located in Denver, Colorado, provides thorough treatment for substance abuse and concurrent mental health issues for both adults and children. Their services feature various levels of care, including intensive outpatient programs, outpatient services, and day treatment. Emphasizing techniques like 12-step support, anger management, and focused interventions, this center customizes its approach to suit each person's requirements. Unique programs are available for active duty military members, as well as separate tracks for adult men and women. AspenRidge Recovery is dedicated to delivering exceptional care and assistance to individuals of all genders striving to conquer addiction and mental health difficulties.

AspenRidge Recovery
Fort Collins, CO

AspenRidge Recovery, located in Fort Collins, CO, delivers extensive treatment for substance use disorders alongside tailored support for adults facing serious mental health issues and children dealing with significant emotional challenges. The center features a variety of programs, including intensive outpatient options, outpatient services, and partial hospitalization. Emphasizing methods such as 12-step facilitation, anger management, and short-term intervention strategies, this facility is designed for active military members as well as both adult men and women. AspenRidge Recovery is committed to providing personalized care and effective rehabilitation solutions for adults and young adults of all genders.

Aspire Health Partners

Aspire Health Partners, situated in Orlando, FL, delivers extensive addiction recovery services for both adults and young adults. This facility offers hospital-based detoxification and round-the-clock inpatient support, employing methods like 12-step programs, brief interventions, and cognitive behavioral therapy. The center is particularly skilled in helping pregnant and postpartum women while also serving male clients. Prioritizing individualized care and tailored treatment strategies, Aspire Health Partners serves as an important resource for those in need of effective substance abuse rehabilitation in a nurturing setting.

AspenRidge Recovery
Colorado Springs, CO

AspenRidge Recovery, situated in Colorado Springs, CO, provides extensive treatment for substance use disorders while also addressing accompanying serious mental health issues in adults and significant emotional challenges in children. The center offers diverse treatment options such as intensive outpatient programs, outpatient services, and partial hospitalization. Emphasizing techniques like 12-step facilitation, anger management, and brief intervention, AspenRidge serves active duty military members as well as adult males and females. This facility is dedicated to delivering personalized, high-quality care to assist both adults and young adults of all genders in their recovery journey.

Aspire Indiana Health
Indianapolis, IN

Aspire Indiana Health in Indianapolis, IN, delivers extensive addiction recovery services via individualized outpatient treatment plans. The facility offers medication-assisted treatment options including methadone, buprenorphine, or naltrexone. They also provide standard outpatient care and specialized therapeutic interventions for individuals dealing with trauma. Approaches employed at Aspire Indiana Health include anger management, cognitive behavioral therapy, and community reinforcement with voucher incentives. This center serves adults and seniors, welcoming individuals of all genders. Aspire Indiana Health is committed to providing excellent, customized support to guide individuals toward overcoming substance dependency.

Aspire Indiana Health
Indianapolis, IN

Aspire Indiana Health, located in Indianapolis, IN, delivers focused outpatient care for individuals battling substance use disorders and co-occurring severe mental health challenges in adults, as well as serious emotional disturbances affecting children. Their therapeutic offerings include strategies like anger management, cognitive behavioral therapy, and community reinforcement with voucher incentives. Aspire Indiana Health designs individualized programs for adult men, adult women, and those who have undergone trauma, acknowledging a variety of client requirements. Catering to adult and senior populations of all genders, the center is dedicated to providing high-quality services through outpatient methadone, buprenorphine, or naltrexone treatments, alongside routine outpatient support.

Aspire Indiana Health
Noblesville, IN

Aspire Indiana Health, situated in Noblesville, IN, specializes in outpatient treatments for substance use disorders and offers dedicated services for those facing both substance use issues and significant mental health challenges. The center administers outpatient treatment options, including methadone/buprenorphine and naltrexone therapy, utilizing proven strategies like anger management, cognitive behavioral therapy, and community reinforcement with vouchers. With customized programs designed for adult males, females, and those who have experienced trauma, Aspire Indiana Health serves a diverse clientele, including adults and seniors across all gender identities. The facility is committed to providing personalized, top-notch care that fosters recovery and promotes comprehensive healing.

Aspire Indiana Health

Aspire Indiana Health, located in Lebanon, IN, provides a variety of outpatient programs designed for adults and seniors who are grappling with both substance use and mental health challenges. This center is particularly equipped to assist individuals who have experienced trauma and offers tailored programs based on gender for both men and women. Their treatment techniques incorporate anger management, cognitive behavioral therapy, and community reinforcement with vouchers. Aspire Indiana Health is recognized for its empathetic approach and adherence to evidence-based methods, including outpatient options for methadone/buprenorphine or naltrexone treatment. By emphasizing personalized care, this center is committed to helping clients in their recovery journey.

Aspire Indiana Health

Aspire Indiana Health, located in Anderson, IN, specializes in treating adult men who are confronting significant emotional issues alongside substance use disorders. This center provides both residential and short-term residential services, emphasizing anger management, cognitive behavioral therapy, and community reinforcement strategies, including vouchers. Aspire Indiana Health serves a diverse clientele, comprising adults, seniors, and young adults, in a secure and nurturing setting for individuals impacted by trauma. With a committed staff and customized treatment plans, this facility delivers high-quality care and successful interventions for individuals aiming to triumph over addiction and mental health difficulties.

Aspire Indiana Health

Aspire Indiana Health, located in Anderson, IN, delivers outpatient treatment for substance use, along with focused programs for adults facing significant mental health issues. This center offers outpatient services utilizing methadone, buprenorphine, or naltrexone, as well as standard outpatient care. Emphasis is placed on anger management, cognitive behavioral therapy, and the community reinforcement approach, which includes the use of vouchers. With customized programs for adult men, women, and individuals with trauma backgrounds, Aspire Indiana Health serves adults and seniors across genders. The center is dedicated to providing high-quality care and a holistic strategy to tackle both substance use and mental health difficulties.

Aspire Indiana Health

Aspire Indiana Health, situated in Anderson, IN, stands out as a premier rehabilitation facility focused on addressing substance abuse in adults and the elderly. The center provides options for outpatient treatment using methadone, buprenorphine, or naltrexone, alongside regular outpatient services and customized programs. Committed to delivering exceptional care, Aspire Indiana Health emphasizes approaches such as anger management, cognitive behavioral therapy, and community reinforcement with vouchers. Each client receives a personalized treatment plan, adapting to their specific circumstances to foster sustainable recovery and overall well-being, regardless of their gender.

Aspire Indiana Health

Aspire Indiana Health, located in Elwood, IN, specializes in outpatient services for adults facing substance use issues as well as serious mental health disorders, and it also caters to children dealing with significant emotional challenges. The center offers a variety of evidence-based treatment methods such as cognitive behavioral therapy, anger management, and community reinforcement featuring vouchers. Programs are customized to meet the needs of adult men and women, as well as individuals who have undergone trauma, ensuring a personalized approach to care. This facility serves all genders among adults and seniors, providing outpatient treatments with methadone, buprenorphine, or naltrexone, alongside standard outpatient services, emphasizing a commitment to effective care and holistic support for clients on their recovery journeys.

Asociacion Puertorriquenos en Marcha

Asociacion Puertorriquenos en Marcha, located in Philadelphia, PA, provides extensive outpatient rehabilitative care. This facility focuses on aiding individuals struggling with addiction and co-occurring mental health conditions, serving both young and adult patients. Their treatment modalities encompass substance abuse recovery, including options for medically supervised withdrawal and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Counseling techniques employed involve structured support for 12-step programs, strategies for managing anger, and targeted, short-term interventions. Special offerings are designed for active military members, teenagers, and adult males. The center welcomes clients of all genders and ages, committed to offering high-caliber support and individually tailored recovery paths.

Aspire Health Partners

Aspire Health Partners, located in Orlando, FL, provides a wide range of addiction treatment options for both adults and young adults who are dealing with substance use disorders and concurrent mental health issues. Their offerings encompass detox services, intensive outpatient programs, and outpatient detoxification, emphasizing techniques such as 12-step support, anger management, and brief therapeutic interventions. This center is equipped to address the unique needs of individuals who have faced trauma, as well as those who are pregnant or in the postpartum period. Aspire Health Partners is committed to creating a nurturing and inclusive atmosphere for all clients, with programs specifically designed for both men and women. Their commitment to high-quality, research-driven care positions this center as a leading choice for individuals striving to conquer their addiction.

Aspire Indiana Health

Aspire Indiana Health, located in Carmel, Indiana, specializes in outpatient treatment for substance use issues, as well as offering targeted support for individuals facing severe mental health challenges or emotional issues. The facility employs a variety of therapeutic methods, including cognitive behavioral therapy, anger management sessions, and community reinforcement strategies with incentives. Programs are designed to cater to adult men and women, including those who have undergone traumatic experiences, effectively providing services to all adult demographics. The center provides outpatient options with medications like methadone, buprenorphine, or naltrexone, along with standard outpatient care. Patients can look forward to personalized treatment plans that ensure a high standard of care throughout their recovery process.

Aspire Indiana Health

At Aspire Indiana Health in Anderson, IN, we provide extensive outpatient rehabilitation for adults and seniors facing challenges with addiction and co-occurring mental health conditions. Our programs are customized to meet specific needs, incorporating interventions like anger management, cognitive behavioral therapy, and community reinforcement. Aspire Indiana Health is committed to a distinct, personalized approach to care, guaranteeing every individual receives focused attention. We offer outpatient services for both men and women, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside our regular outpatient care. Opt for Aspire Indiana Health for effective, research-backed treatment within a nurturing setting.

Placeholder image

Aspell Recovery Center, located in Jackson, TN, presents a wide array of services for those in need of substance abuse rehabilitation and transitional housing. This center specializes in assisting adults who are faced with both substance use disorders and significant mental health challenges, as well as providing support for children's emotional issues. The treatment options available encompass intensive outpatient care, long-term residential stays, and various outpatient programs. These programs employ diverse therapeutic methods, including 12-step initiatives, anger management techniques, and brief interventions. Aspell Recovery Center is dedicated to supporting adult men and women, particularly those experiencing dual diagnoses. Committed to delivering high-quality care, the center tailors personalized treatment strategies to address the unique needs of adults and young adults of all backgrounds.

Placeholder image

In Albany, Georgia, Aspire Behavioral Health delivers thorough recovery programs for adults and young adults facing addiction and dual mental health challenges. They offer inpatient hospital detox and therapy, with dedicated services for active military members, adult men, and women. Utilizing proven methods such as cognitive behavioral therapy and community reinforcement, Aspire Behavioral Health crafts personalized care plans for every individual. This center is distinguished by its dedication to high-quality treatment and specialized offerings for various demographics, positioning it as a premier option for those in search of successful and caring addiction recovery.

Placeholder image
Portsmouth, NH

Aspire365, located in Portsmouth, NH, provides focused treatment for adults facing substance use issues alongside severe mental health disorders, as well as for children dealing with significant emotional challenges. The center offers both intensive outpatient and outpatient services, including methadone and buprenorphine options, ensuring personalized care through methods like anger management, cognitive behavioral therapy, and community reinforcement strategies. It features distinct programs tailored for active duty military personnel, adolescents, and adult males, addressing a variety of unique needs. Aspire365 serves individuals of all genders, including both adults and children/adolescents, and is recognized for its commitment to delivering high-quality care in a nurturing atmosphere, making it a leading option for those in search of thorough addiction treatment.

Placeholder image
New Haven, CT

Aspire365, situated in New Haven, CT, provides expert care for individuals facing addiction and co-occurring mental health challenges, serving both young people and adults. The facility offers a spectrum of treatment, including intensive outpatient programs, general outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic methods incorporate anger management techniques, cognitive behavioral therapy, and community reinforcement strategies augmented by voucher incentives, ensuring a personalized recovery plan. Specialized programs are offered for active-duty military personnel, teenagers, and adult men. Aspire365 is dedicated to delivering high-quality support for all clients, encompassing adults and children/adolescents across all gender identities, on their journey to wellness.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)