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Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Atascosa SUD Outpatient Clinic

Situated in Jourdanton, Texas, the Atascosa SUD Outpatient Clinic delivers a wide array of services for addiction recovery. This center focuses on detox and treatment for substance use, providing various levels of care, including intensive outpatient programs, general outpatient services, and partial hospitalization options. The clinic employs proven methodologies like the Matrix Model, strategies for relapse prevention, and counseling directed at substance use disorders. It supports a diverse population, including active duty military personnel, adolescents, and adult males. Committed to serving individuals of all ages and genders, the Atascosa SUD Outpatient Clinic is dedicated to offering customized and high-quality care, making it a premier option for those in need of effective addiction recovery solutions.

Atlanta Recovery Place

Atlanta Recovery Place located in Atlanta, GA, offers a range of services including intensive outpatient treatment, outpatient programs, and day treatment specifically designed for individuals facing substance use challenges. Emphasizing 12-step methods, anger management techniques, and brief intervention strategies, this center provides tailored programs for adolescents as well as adult men and women. Catering to both adults and younger clients, the facility is inclusive for all genders. Atlanta Recovery Place distinguishes itself through its holistic approach to addiction recovery, guaranteeing exceptional care and assistance for those striving to overcome substance use issues.

Atrium Health
Kings Mountain, NC

Atrium Health, located in Kings Mountain, NC, delivers a complete spectrum of addiction recovery programs for adults and younger individuals. This institution features hospital-based inpatient detox and treatment for substance dependency, alongside mental health concerns and emotional challenges that often co-occur. Atrium Health utilizes proven therapeutic techniques such as guided 12-step participation, rapid intervention strategies, and motivational interviewing to foster lasting recovery. They offer targeted programs for those affected by trauma, individuals with dual diagnoses, and people managing chronic pain alongside substance use. Committed to high standards of care, Atrium Health welcomes both men and women seeking successful rehabilitation.

Atrium Health Mercy
Charlotte, NC

Atrium Health Mercy, situated in Charlotte, NC, delivers thorough detox programs for adults and young adults. This center offers inpatient hospital detoxification and round-the-clock hospital inpatient treatment, employing methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy. Emphasizing personalized care, the facility welcomes both male and female patients. Atrium Health Mercy distinguishes itself with its dedication to high-quality treatment and customized plans designed for individual requirements. For effective addiction recovery in a nurturing setting, this center may be an ideal option for your healing path.

Augustine Recovery Center
Saint Augustine, FL

Augustine Recovery Center, situated in Saint Augustine, FL, delivers thorough addiction treatment and tailored support for adult men managing dual diagnoses. The center provides robust outpatient, extended residential, and standard outpatient care, incorporating methods such as 12-step support and emotional regulation techniques. Specialized offerings address individuals who have faced intimate partner violence, domestic abuse, and sexual trauma. Focusing on adult men, including seniors and young adults, this establishment is dedicated to delivering high-quality care within a nurturing setting. Augustine Recovery Center stands out as a premier option for those pursuing successful recovery programs in a male-focused environment.

Associated Catholic Charities

Based in Baltimore, MD, Associated Catholic Charities delivers outpatient treatment for substance use disorders, designed for both adults and children who also experience mental health challenges. The facility specializes in outpatient therapies such as methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Emphasizing 12-step support, anger management, and brief interventions, the center is tailored to serve clients with overlapping diagnoses. It welcomes individuals of all genders, focusing on personalized care and research-backed methods to provide effective treatment for those on the path to recovery from substance use issues and related mental health concerns.

Astra Recovery Centers LLC

Astra Recovery Centers LLC, located in Bardstown, KY, delivers a thorough array of treatment options for adults and adolescents grappling with addiction and co-occurring psychological conditions. This establishment provides intensive outpatient, extended residential, and general outpatient care, all personalized to suit each person's specific requirements. Emphasizing 12-step integration, emotional regulation techniques, and short-term counseling strategies, the center offers targeted support for male patients. Distinctive offerings for active military members, adult men, and survivors of domestic abuse distinguish this center. Astra Recovery Centers LLC is committed to delivering effective, research-backed therapy to foster sustained well-being.

Athens Treatment Services

Athens Treatment Services, located in Athens, OH, provides outpatient programs designed for adults and young adults dealing with substance use issues. The center focuses on methadone/buprenorphine and naltrexone treatments, employing evidence-supported techniques like brief intervention, cognitive-behavioral therapy, and motivational incentives. With an emphasis on the unique needs of pregnant and postpartum women, Athens Treatment Services serves clients of all genders, ensuring personalized and thorough care. The center is recognized for its specialized programs and dedication to offering effective, high-quality treatment to individuals on their journey to recovery from substance use disorders.

Astra Behavioral Health
Elizabethtown, KY

Astra Behavioral Health in Elizabethtown, KY, delivers a complete spectrum of care for individuals grappling with addiction and coinciding mental health conditions, serving adults and young adults. Their services include intensive outpatient, outpatient, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing proven methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the center is equipped to support adult men, adult women, and those with dual diagnoses. Astra Behavioral Health prioritizes personalized treatment plans, guaranteeing effective support for both men and women on their journey to overcome substance abuse and mental health issues.

Associated Catholic Charities

Associated Catholic Charities in Baltimore, MD, provides outpatient treatment for adults struggling with substance use. They also offer specialized care for those facing co-occurring substance use and serious mental health conditions or emotional challenges. Their services encompass programs such as anger management, brief intervention, and cognitive behavioral therapy. Each patient receives a customized treatment plan, ensuring a unique and personal recovery journey. Catering to adults and seniors of all genders, this center prioritizes delivering excellent care to foster healing. For those in need of effective, tailored treatment for substance use and co-occurring disorders, Associated Catholic Charities is committed to supporting your journey toward well-being.

Athens Area Commencement Center

Athens Area Commencement Center, situated in Athens, GA, provides thorough addiction recovery for adults and young people. They offer detox and substance use treatment via intensive outpatient, outpatient, and day programs. Their approach includes 12-step support, brief intervention, and cognitive behavioral therapy, serving all genders with specialized tracks for teens, adult men, and adult women. The center's dedication to excellent care and personalized recovery paths establishes it as a reliable option for effective and compassionate rehabilitation.

Aurora Behavioral Health Center

Aurora Behavioral Health Center, situated in Sheboygan, WI, provides extensive support for individuals of all ages battling addiction and coinciding mental health challenges. Their treatment options include intensive outpatient, outpatient, and partial hospitalization programs, employing methods like anger management, cognitive behavioral therapy, and brief intervention strategies. Aurora Behavioral Health Center is dedicated to personalized care for adult men and women, as well as young adults, aiming for effective and customized recovery journeys. Discover exceptional support and personally crafted treatment paths at this establishment for a complete path to healing.

Associated Catholic Charities

Associated Catholic Charities in Frederick, MD, delivers extensive outpatient care for individuals of all ages struggling with substance abuse and co-occurring severe mental health challenges. They offer distinct programs tailored for teens, adult men, and adult women, incorporating evidence-based methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. Their approach includes personalized outpatient medication management with methadone, buprenorphine, or naltrexone, guaranteeing a customized treatment plan for every patient. This facility is dedicated to providing high-quality, compassionate care grounded in proven therapeutic techniques for adults, children, and adolescents alike.

Atlantic Behavioral Health

Atlantic Behavioral Health, situated in Florham Park, NJ, delivers extensive addiction treatment options for both adults and young adults. With a focus on addressing co-occurring disorders involving substance use and mental health issues, the center offers a range of services including intensive outpatient programs, outpatient care, and treatments utilizing methadone, buprenorphine, or naltrexone. Incorporating evidence-based practices such as 12-step programs, cognitive behavioral therapy, and motivational interviewing, the facility develops customized treatment plans for adult men, women, and clients who have faced trauma. Atlantic Behavioral Health is committed to providing personalized care within a nurturing setting, ensuring high-quality support for individuals dealing with substance use and co-occurring conditions.

Atlanticare Behavioral Health

Atlanticare Behavioral Health, located in Hammonton, NJ, provides an extensive array of specialized rehabilitation services aimed at assisting adults and young adults facing substance use challenges along with concurrent mental health conditions. The center offers intensive outpatient programs, outpatient detox services, and therapeutic sessions that incorporate evidence-based methods like cognitive behavioral therapy and motivational interviewing. Emphasizing a personalized approach, Atlanticare Behavioral Health customizes treatment plans to align with each individual's specific requirements. Among its unique offerings are programs for anger management and therapy tailored for different genders. The center is dedicated to delivering exceptional, personalized support to aid clients in their recovery journey.

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Associated Catholic Charities in Abingdon, MD, delivers an extensive outpatient program for adults experiencing substance use issues alongside mental health challenges, as well as support for children facing significant emotional difficulties. The center is focused on personalized care, offering outpatient treatments with methadone, buprenorphine, or naltrexone, in addition to standard outpatient services. By catering to the specific requirements of each client, the center emphasizes high-quality care for both men and women. Committed to a holistic approach, this facility strives to provide compassionate and effective treatment, aiding individuals in their recovery journey.

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Associated Catholic Charities in Dundalk, MD, specializes in outpatient addiction recovery for adults and adolescents facing concurrent mental health challenges. They offer medication-assisted treatment, including methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Employing evidence-based approaches like anger management, cognitive behavioral therapy, and motivational interviewing, the center crafts individualized treatment strategies. Their distinctive personal focus guarantees customized support for adults and older adults, irrespective of gender. Associated Catholic Charities is committed to delivering top-tier, holistic rehabilitation, empowering clients on their journey to sustained healing and enhanced psychological health.

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Atrium Health Addiction Services, situated in Charlotte, NC, specializes in treating adults facing substance use issues alongside co-occurring mental health disorders, as well as addressing serious emotional challenges in children. The center offers a range of treatment options, including intensive outpatient programs, standard outpatient services, and medication-assisted therapies such as methadone, buprenorphine, or naltrexone. By employing techniques like brief interventions, cognitive behavioral therapy, and motivational incentives, the center ensures that its programs are customized for each individual. Catering to all adults and young adults, Atrium Health Addiction Services is recognized for its personalized care and dedication to providing high-quality treatment. If you or someone you know is in need of effective and tailor-made addiction support, this esteemed facility may be a solid choice.

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Atrium Health Addiction Services, situated in Charlotte, NC, provides tailored care for individuals battling substance use disorders and co-occurring mental health challenges. The center caters to both young people and adults, offering various levels of support including intensive outpatient services, general outpatient care, and medication-assisted treatment. Employing proven therapeutic techniques such as cognitive behavioral therapy and contingency management, the program crafts unique treatment journeys for each patient. Atrium Health Addiction Services emphasizes personalized support for clients of all genders, making it a distinguished choice for those in search of effective and comprehensive addiction recovery within a nurturing setting.

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ATS of Cecil County Inc in Baltimore, MD, provides tailored substance abuse recovery services for adults and young adults. Their offerings include outpatient care, as well as specialized programs utilizing methadone/buprenorphine or naltrexone, alongside standard outpatient services. Emphasizing personalized support, the center incorporates methods such as 12-step facilitation, anger management, and brief intervention to combat addiction. ATS of Cecil County Inc serves a diverse clientele, welcoming both men and women into a nurturing setting. For those in search of thorough addiction treatment that prioritizes individual needs, this center is committed to delivering excellent care to support each person's path to wellness.

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Fayetteville, AR

Situated in Fayetteville, AR, Aurora is a dedicated rehabilitation facility providing outpatient care for adults and young adults struggling with substance use. The center offers diverse treatment modalities, encompassing standard outpatient services, medication-assisted treatment (methadone, buprenorphine, naltrexone), and general outpatient programs. Aurora prioritizes a personalized treatment philosophy, focusing on strategies such as contingency management, relapse prevention, and specialized counseling for substance use disorders. Their programs are designed to meet the distinct needs of both male and female patients. By developing individualized recovery plans, Aurora commits to delivering exceptional support for those seeking lasting sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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