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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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My Time Recovery LLC

My Time Recovery LLC, located in Fresno, CA, specializes in a wide range of addiction treatment options for both adults and young adults facing substance use challenges. The center offers various services, including residential detox, continuous residential support, and short-term care programs. Utilizing proven methods such as the 12-step approach, motivational interviewing, and strategies for preventing relapse, the facility customizes treatment plans to fit the unique needs of each client. A standout aspect of the program is its commitment to delivering a personalized experience for everyone. With dedicated programs for men and women, My Time Recovery LLC fosters a supportive atmosphere tailored to individual needs. For those looking for effective and empathetic addiction treatment, this center is a commendable choice.

NATIVE Project
Spokane, WA

The NATIVE Project, situated in Spokane, WA, specializes in substance use rehabilitation for adults facing significant mental health challenges alongside children dealing with emotional disturbances. The center offers both intensive outpatient and outpatient programs, featuring a variety of services such as 12-step support, anger management classes, and short-term interventions. Programs are specifically designed for adolescents, as well as adult men and women, ensuring that care is customized to the individual's needs. NATIVE Project caters to a diverse clientele, including adults, adolescents, and young adults, focusing on high-standard, evidence-informed treatment that respects cultural backgrounds. If you are looking for a holistic approach to addiction recovery with an emphasis on mental health care, this center provides extensive resources to aid your healing process.

NOLA Detox and Recovery Center

NOLA Detox and Recovery Center, situated in New Orleans, LA, delivers extensive addiction rehabilitation for adults and adolescents. This establishment features extended stay residential programs, inpatient detox services, and continuous round-the-clock residential assistance. The center's expertise lies in addressing substance use issues, coexisting mental health challenges, and emotional difficulties in youth. Emphasizing 12-step integration, anger resolution techniques, and focused intervention strategies, the program serves both genders, accommodating individuals with a history of sexual trauma. Patients will receive tailored support and scientifically proven therapeutic methods to achieve lasting sobriety.

NOW Counseling Services LLC

NOW Counseling Services LLC, situated in Rockport, IN, provides an extensive array of addiction recovery services tailored for both adults and young adults. The center specializes in detoxification, substance use therapy, transitional housing, and options for sober living. Available treatment formats encompass intensive outpatient, outpatient, and day treatment programs. With targeted initiatives for active duty military personnel, adults of both genders, the facility addresses a variety of requirements. The center utilizes evidence-based techniques, including 12-step facilitation, anger management, and brief intervention, to deliver personalized care. Catering to both female and male clients, NOW Counseling Services LLC emphasizes high-quality support and resources for individuals on their journey to recovery.

NE Arkansas Community MH Center

NE Arkansas Community MH Center located in Marianna, AR, focuses on delivering tailored outpatient services for adults dealing with substance use issues and co-occurring serious mental health conditions, as well as for children coping with significant emotional disturbances. The center features ongoing outpatient initiatives such as brief interventions, cognitive behavioral therapy, and the Matrix Model. Adopting a personalized strategy, the facility serves adults and seniors of various genders. With a committed team of professionals, this center provides extensive care and support for individuals striving for recovery from addiction and mental health difficulties.

My Healing Space Counseling PLLC

My Healing Space Counseling PLLC, situated in Aurora, Colorado, provides a wide array of outpatient programs aimed at treating substance use disorders in adults and young adults. Focusing on individuals with both substance use and significant mental health challenges, this center utilizes evidence-based practices like cognitive behavioral therapy and motivational interviewing. It offers specialized programs designed for active military personnel as well as adult men and women, addressing varied requirements. The facility provides outpatient options including methadone, buprenorphine, and naltrexone treatments, ensuring personalized care for each client. Committed to delivering high-quality support, the center develops individualized treatment plans to effectively aid clients in their recovery processes.

NM Department of Health

Situated in Albuquerque, NM, the NM Department of Health delivers a wide range of services for addiction rehabilitation. This center specializes in inpatient detoxification and treatment aimed at both adults and young adults facing substance use challenges. Utilizing evidence-supported methods, the center incorporates 12-step programs, brief interventions, and cognitive behavioral therapy into its treatment plans. With tailored programs for men and women, the facility addresses the unique needs of its clientele. Emphasizing personalized care, this center provides effective support to individuals striving to conquer addiction.

My Hope 2020 at MIH Experience Ltd

My Hope 2020 at MIH Experience Ltd, located in New York, NY, offers comprehensive outpatient services for individuals battling substance abuse. Their expertise extends to treating co-occurring mental health conditions in adults, as well as addressing emotional challenges in children. The program incorporates medication-assisted treatment, including methadone, buprenorphine, or naltrexone, and employs evidence-based therapies like anger management, CBT, and brief interventions. Emphasizing personalized treatment plans, My Hope 2020 serves a diverse population of adults and young adults, delivering dedicated and effective support for recovery.

Myrtle Beach Treatment Specialists

Myrtle Beach Treatment Specialists, situated in Myrtle Beach, SC, provides an array of outpatient rehabilitation options for adults and young people facing challenges related to substance use disorders. This center features targeted detoxification services and outpatient treatment using methadone/buprenorphine or naltrexone. Their methodology incorporates evidence-based practices, including brief interventions, cognitive behavioral therapy, and motivational incentives/contingency management. Designed to meet the needs of adult men, women, and those who have experienced intimate partner or domestic violence, the facility ensures personalized treatment. Myrtle Beach Treatment Specialists is committed to offering compassionate and effective addiction recovery solutions for both men and women.

NMSAS Recovery Center

Situated in Gaylord, MI, NMSAS Recovery Center delivers outpatient care for both adults and young adults dealing with substance use issues. This facility features targeted programs specifically designed for adult men, women, and those who have faced trauma. By employing methods like cognitive behavioral therapy, contingency management, and motivational interviewing, NMSAS ensures that treatment is customized to meet each person's unique needs. In addition to regular outpatient services, the center provides treatment options involving methadone, buprenorphine, or naltrexone, extending its support to male and female clients alike. Committed to high-quality care and individualized assistance, this center aims to empower individuals on their journey to sustainable recovery.

NE Arkansas Community MH Center

The NE Arkansas Community MH Center, located in Paragould, AR, specializes in providing outpatient treatment for substance use issues and has expertise in addressing co-occurring mental health disorders in adults, along with emotional challenges in children. The center features a variety of services, including outpatient day therapy, partial hospitalization, and traditional outpatient care. Employing methodologies like brief intervention, cognitive behavioral therapy, and the Matrix Model, the facility emphasizes personalized care for adults and seniors, regardless of gender. Dedicated to delivering exceptional and customized treatment plans, the NE Arkansas Community MH Center is distinguished by its extensive programs aimed at fostering recovery and overall wellness.

NCH Patient Care Center Colebrook

NCH Patient Care Center Colebrook, situated in Colebrook, NH, delivers expert outpatient services for adults grappling with substance use disorders and co-occurring mental health conditions, alongside specialized support for children experiencing emotional disturbances. Their treatment options encompass outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone) and standard outpatient therapy. The center champions personalized care, designing bespoke programs for adults and young individuals across all gender identities. Employing evidence-based strategies such as 12-step facilitation, anger management, and brief intervention techniques, NCH Patient Care Center Colebrook is dedicated to providing thorough and tailored recovery support. They are committed to delivering high-quality, individualized treatment experiences.

NE Arkansas Community MH Center

NE Arkansas Community MH Center, located in Walnut Ridge, AR, provides outpatient services for individuals struggling with substance use disorders. They also specialize in addressing co-occurring conditions, offering support for adults with serious mental health illnesses and children experiencing serious emotional disturbances. Employing techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center develops personalized treatment plans for adults and seniors across all genders. Their commitment to an individualized approach guarantees high-quality care customized to each person's specific requirements. For those looking for scientifically proven treatments within a supportive setting, this center could be an excellent resource for embarking on a path to recovery.

NE Arkansas Community MH Center

The NE Arkansas Community MH Center, situated in Helena, AR, delivers targeted substance use interventions. Their expertise lies in addressing the complex interplay of addiction and co-occurring mental health challenges, serving adults with serious mental health conditions and children with emotional disturbances. Through an outpatient framework, the center employs proven therapeutic modalities, including brief intervention, cognitive behavioral therapy, and the Matrix Model. Prioritizing a personalized approach, the NE Arkansas Community MH Center is equipped to assist adults and seniors, irrespective of gender, on their path to sustained recovery with dedicated and tailored care.

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The NCWR Addiction Recovery Clinic at OSU in Tulsa, OK, provides outpatient detox and treatment services for adults dealing with serious mental health issues alongside substance use disorders. Employing methods such as brief interventions, cognitive behavioral techniques, and motivational interviewing, this center delivers personalized support for both men and women. It emphasizes outpatient care with specialized treatment options like methadone, buprenorphine, or naltrexone tailored to fit the distinct requirements of each client. With an emphasis on high-quality care and a dedication to fostering enduring recovery, this clinic offers a nurturing space for individuals seeking extensive addiction treatment solutions.

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NOW Counseling Services LLC, situated in Evansville, IN, delivers a complete spectrum of substance abuse recovery options for adults and adolescents. Their offerings encompass detox, drug and alcohol treatment, and specialized support for individuals facing both addiction and significant mental health challenges. Programs available include intensive outpatient care, standard outpatient services, and day treatment or partial hospitalization. Emphasizing techniques like 12-step encouragement, anger control, and brief counseling, the facility serves the distinct needs of active military members, adult men, and adult women. NOW Counseling Services LLC prioritizes high-quality, individualized care, positioning them as a leading facility for those in search of impactful and customized recovery solutions.

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NOW Counseling Services LLC in Evansville, IN, provides extensive addiction recovery options for adult women within a residential environment. The facility focuses on long-term residential treatment, detoxification services, and around-the-clock residential programs. Employing techniques such as 12-step support, anger management, and brief interventions, it serves individuals grappling with both substance use issues and significant mental health disorders. The center also features specialized programs for active military members, adult women, and those who have experienced intimate partner violence. By concentrating on adults, seniors, and young adults, and exclusively supporting female clients, this center delivers customized, high-quality treatment aimed at aiding individuals in overcoming substance use disorders and mental health obstacles.

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NOW Counseling Services LLC, located in Evansville, IN, focuses on the treatment of substance addiction and concurrent severe mental health disorders. The center provides various options, including outpatient services, day treatment programs, and partial hospitalization. They employ methods such as 12-step facilitation, anger management, and brief interventions. With specialized programs aimed at active duty military members and both men and women, NOW Counseling Services accommodates adults and young adults of all genders. Their dedication to delivering high-quality care and customized treatment strategies distinguishes them as a leading provider of rehabilitation services in the Evansville region.

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NOW Counseling Services LLC in Evansville, IN, offers a complete suite of recovery solutions for adults and adolescents. The facility provides detox services, addiction treatment, and dedicated support for individuals facing both substance use disorders and significant mental health conditions. Their treatment options encompass intensive outpatient, extended residential stays, and standard outpatient care. Employing methods like 12-step encouragement, emotional regulation techniques, and short-term counseling, this center welcomes individuals from all walks of life. Specific provisions are made for active service members, adult males, and survivors of domestic abuse. By delivering customized care for male and female patients, NOW Counseling Services LLC guarantees empathetic and successful recovery journeys for those pursuing freedom from addiction.

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NOW Counseling Services LLC in Evansville, IN, is dedicated to providing comprehensive recovery solutions for adult men struggling with addiction and co-occurring mental health disorders. The center offers various levels of care, including extended residential stays, detox services within a residential setting, and round-the-clock residential treatment. Their therapeutic framework incorporates proven methods like 12-step integration, emotional regulation training, and short-term counseling strategies. NOW Counseling Services LLC is equipped to support active military members and individuals who have faced domestic abuse, serving adult, senior, and young adult males.

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NR Pennsylvania Associates LLC in Ephrata, PA, delivers extensive addiction recovery support for adults and adolescents. The facility is equipped to handle individuals facing dual diagnoses of substance use disorders and significant mental health conditions. Clients can access various levels of care, including inpatient detox, round-the-clock residential treatment, and brief residential stays. Their therapeutic approach emphasizes 12-step integration, emotional regulation skills, and cognitive restructuring, all customized to each person's recovery journey. Special provisions are made for active military members, and those impacted by domestic abuse, intimate partner violence, or sexual trauma. NR Pennsylvania Associates LLC is dedicated to providing excellent support for men and women on their path to lasting sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)