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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Nash UNC Healthcare
Rocky Mount, NC

Nash UNC Healthcare, located in Rocky Mount, NC, delivers an extensive array of addiction treatment options for both adults and elder individuals facing challenges related to substance use disorders and simultaneous mental health conditions. The center features inpatient detoxification services and treatment programs with around-the-clock supervision. Emphasizing personalized counseling for substance use disorders, this facility is committed to tailoring care to the specific needs of each patient. Nash UNC Healthcare serves clients of all genders, creating a welcoming and supportive atmosphere. If you or someone you care about is in search of high-quality addiction care with a customized approach, this center is focused on providing effective and empathetic support.

Nassau University Medical Center

Nassau University Medical Center, situated in East Meadow, NY, delivers extensive substance abuse recovery services for adults and adolescents. This hospital-based inpatient program emphasizes 12-step support, emotional regulation skills, and short-term counseling techniques. Designed to meet unique requirements, the center features distinct programs for male and female patients. Dedicated to providing excellent support, Nassau University Medical Center fosters a nurturing atmosphere for individuals addressing addiction. For those seeking customized and impactful addiction recovery, this institution is committed to guiding you toward a well, substance-free future.

NYCHHC/Jacobi Medical Center

Located in the Bronx, NYCHHC/Jacobi Medical Center provides a wide range of addiction care services for both adults and young adults. The facility specializes in detox, treatment for substance use, and targeted support for those facing concurrent addiction and severe mental health issues. Available treatment modalities include intensive outpatient programs, standard outpatient services, and detox programs. Emphasizing strategies like 12-step support, anger management, and brief intervention techniques, the center serves adult males and females, as well as clients who have suffered from intimate partner violence. NYCHHC/Jacobi Medical Center is committed to delivering personalized care that meets the individual requirements of each patient, promoting successful recovery results.

Naaman Center
Elizabethtown, PA

Situated in Elizabethtown, PA, the Naaman Center provides comprehensive substance abuse recovery services. Their offerings include intensive outpatient, standard outpatient, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center excels in delivering brief interventions, cognitive behavioral therapy, and community reinforcement strategies augmented with voucher incentives. Catering to distinct demographics, they offer specialized programs for adult men and women, alongside services for children and adolescents, ensuring individualized support. With dedicated gender-specific tracks for males and females, the Naaman Center fosters a secure and understanding atmosphere. Their dedication to evidence-based practices and personalized care highlights their commitment to effective addiction treatment for individuals pursuing lasting sobriety.

Naaman Center
Elizabethtown, PA

Situated in Elizabethtown, PA, Naaman Center provides targeted substance use treatment for individuals of all ages, including adults, children, and teenagers. The center's treatment offerings encompass intensive outpatient services, standard outpatient care, and methadone or buprenorphine and naltrexone options, all designed to meet the specific needs of each client. By employing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, Naaman Center prioritizes effective care with a personalized approach. The facility accommodates both men and women, fostering a thorough and welcoming atmosphere for those looking for successful addiction recovery options.

Nash UNC Healthcare
Rocky Mount, NC

Nash UNC Healthcare, located in Rocky Mount, NC, provides an extensive range of addiction treatment options for both adults and young adults. The center features inpatient detoxification services and treatment programs that emphasize cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders. Each program is customized to meet the unique needs of individuals, guaranteeing focused care. With targeted treatment approaches for male and female participants, Nash UNC Healthcare upholds exceptional quality and efficacy in assisting individuals in overcoming their substance use challenges. If you are looking for professional and empathetic addiction services, this center is committed to guiding you on your recovery path.

Naperville Psychiatric Ventures

Naperville Psychiatric Ventures, located in Naperville, IL, provides targeted interventions for individuals, both young and adult, struggling with addiction and co-occurring mental health conditions. They offer flexible treatment modalities including intensive outpatient, standard outpatient, and partial hospitalization, all designed with individualized care in mind. Therapeutic strategies employed by the center encompass 12-step facilitation, anger management techniques, and brief intervention methods. Specialized services are available for teenagers and individuals managing dual diagnoses. Catering to a diverse clientele, the facility is equipped to support individuals of all ages in their journey toward recovery and sustained well-being.

Narcotics Prevention Association

Situated in Los Angeles, CA, the Narcotics Prevention Association provides a variety of extensive services aimed at assisting individuals on their path to recovery. This center offers detoxification and substance abuse treatment through a combination of intensive outpatient, outpatient, and outpatient detox programs. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, the facility serves adults and seniors of all gender identities. Specialized programs designed for active duty military members, as well as distinct services for adult men and women, ensure focused care. The Narcotics Prevention Association is dedicated to offering personalized treatment that fosters enduring recovery for every client.

Naaman Center
Lancaster, PA

Situated in Lancaster, PA, the Naaman Center provides a wide range of substance use rehabilitation services designed to meet diverse individual requirements. The center features programs such as intensive outpatient care and outpatient options that include methadone, buprenorphine, or naltrexone treatment. Adopting evidence-based techniques like brief interventions, cognitive behavioral therapy, and community reinforcement along with vouchers, the Naaman Center ensures effective support. With dedicated programs for adult males and females, as well as services available for children and adolescents across all genders, the center fosters a nurturing space for healing. Clients can anticipate tailored treatment plans and exceptional care as they work towards a sober lifestyle.

Naperville Psychiatric Ventures

Nestled in Naperville, IL, Naperville Psychiatric Ventures delivers extensive addiction care for individuals of all ages. The facility provides inpatient hospital detoxification and treatment for those struggling with substance use disorders. With expertise in managing co-occurring mental health conditions, they offer targeted programs for patients with dual diagnoses. Emphasizing 12-step support, anger management techniques, and concise intervention strategies, Naperville Psychiatric Ventures customizes care plans to suit each person's unique requirements. Catering to male and female patients, including teenagers, they guarantee high-quality treatment across all age demographics. The center distinguishes itself through its all-encompassing strategy to tackling addiction and mental well-being challenges.

Nassau Alternative Advocacy Program OP

Situated in New Hyde Park, NY, the Nassau Alternative Advocacy Program OP delivers an extensive array of services for those in need of addiction recovery. The center offers detoxification, treatment for substance use disorders, and customized support for adults facing complex mental health challenges or children with significant emotional issues. Treatment modalities include intensive outpatient programs, standard outpatient services, and outpatient detoxification, addressing the needs of both adults and young people of all genders. The facility employs a variety of methods, such as 12-step support, anger management techniques, and brief therapeutic interventions, to provide tailored care. Additionally, there are special programs designed for active military personnel, adolescents, and men, underscoring the center's dedication to serving the varied needs of its community.

NWIHCS/Lincoln VA

NWIHCS/Lincoln VA, located in Lincoln, NE, specializes in rehabilitation services for both adults and children facing challenges related to substance abuse and concurrent mental health issues. The center offers various treatment approaches, such as intensive outpatient programs, outpatient services, and day treatment alternatives. Emphasizing techniques like 12-step support, anger management, and short-term interventions, the facility customizes its offerings to address the unique needs of each individual. The center also features specialized programs for active-duty military members, as well as for adult males and females. Catering to a diverse population that includes adults, seniors, and young individuals of all genders, NWIHCS/Lincoln VA ensures thorough and compassionate care in an encouraging setting for those on their recovery journey.

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Elizabethville, PA

Situated in Elizabethville, PA, the Naaman Center delivers a wide range of treatment options for individuals grappling with substance use issues, including both adults and teenagers. This center specializes in intensive outpatient care as well as general outpatient services, along with methadone, buprenorphine, or naltrexone programs. The Naaman Center employs effective, research-backed methods such as brief intervention, cognitive behavioral therapy, and community reinforcement with vouchers to address the distinct requirements of adult men, women, and youth. With tailored programs designed for different genders and age brackets, the Naaman Center guarantees personalized attention and support for every client in their journey towards recovery. If you're looking for effective addiction treatment in a supportive setting, this facility is committed to aiding you in your recovery process.

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Paradise, PA

Nestled in Paradise, PA, the Naaman Center delivers expert addiction recovery programs for adults and young individuals. Their services include intensive outpatient care, general outpatient support, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention, the center customizes each person's recovery journey. Committed to providing personalized attention, the Naaman Center accommodates both male and female clients in their pursuit of complete addiction rehabilitation. For those in search of effective and caring recovery assistance, this center distinguishes itself through its dedication to high-quality, tailored treatment strategies.

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Lebanon, PA

Naaman Center, situated in Lebanon, PA, delivers targeted interventions for individuals grappling with substance use disorders, catering to both younger and adult demographics. Their array of offerings encompasses intensive outpatient care, standard outpatient services, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing proven methodologies such as cognitive behavioral therapy and community reinforcement with incentives, the center crafts personalized support for adult males and females. Naaman Center prioritizes individualized recovery strategies, assuring high-quality assistance for all clients. This establishment provides robust and empathetic rehabilitation services, designed to guide individuals and their families toward lasting sobriety.

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Naperville Psychiatric Ventures, situated in Plainfield, Illinois, delivers targeted therapy for addiction and associated mental health conditions in both adults and children. The facility offers a range of programs including intensive outpatient treatment, standard outpatient services, and day treatment alternatives, accessible to individuals of all genders. Emphasizing 12-step support, anger management techniques, and short-term interventions, this center is well-prepared to meet diverse patient needs. Focusing on individuals facing dual diagnoses, Naperville Psychiatric Ventures ensures that clients receive thorough care and assistance as they navigate their rehabilitation journey in a supportive atmosphere.

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Detroit, MI

Nardin Park, situated in Detroit, MI, delivers a wide array of substance use rehabilitation services aimed at both adults and young adults. This center specializes in outpatient treatment, offering customized options such as methadone/buprenorphine or naltrexone programs, typical outpatient care, and various evidence-supported strategies like 12-step guidance, brief interventions, and cognitive behavioral therapy. Nardin Park serves adult men and women, including those affected by intimate partner or domestic violence. By concentrating on personalized treatment plans and effective therapeutic methods, this facility commits to providing exceptional care for individuals on their path to recovery from addiction.

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Nashville, TN

Nestled in Nashville, TN, the Nashville rehabilitation center delivers a full spectrum of care for addiction, dual diagnosis, and detox services, serving both adolescents and adults. Their hospital-based inpatient detoxification and treatment options ensure round-the-clock support, emphasizing techniques like anger management, cognitive behavioral therapy, and motivational rewards. This personalized strategy is designed for individuals of all genders and age groups, including young adults. Nashville distinguishes itself through its commitment to high-quality, individualized treatment plans, positioning it as a premier destination for effective and bespoke recovery journeys.

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Situated in East Meadow, NY, the Nassau County Office of MH CD specializes in outpatient treatment for adults dealing with substance use issues alongside significant mental health conditions. The center employs targeted therapies such as cognitive behavioral therapy, motivational interviewing, and brief interventions to effectively support its clients. Programs are designed for both adult men and women, catering to both older and younger adults. The facility offers outpatient options that include methadone, buprenorphine, or naltrexone treatments, focusing on personalized care for individuals navigating recovery from substance use disorders and mental health difficulties. Committed to delivering high-quality care through evidence-based methods, this center is dedicated to aiding individuals on their path to recovery and improved well-being.

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Vernon Rockville, CT

Situated in Vernon Rockville, CT, Natchaug Hospital Inc provides an extensive array of treatment options for adults and young adults confronting substance use issues alongside mental health challenges. The center features intensive outpatient programs, standard outpatient services, and day treatment alternatives. Emphasizing evidence-based techniques such as cognitive-behavioral therapy and motivational interviewing, it also includes specialized tracks for those experiencing co-occurring disorders and for young adults. Natchaug Hospital Inc serves both men and women, ensuring a nurturing atmosphere designed to support individuals on their journey towards sustainable recovery.

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Mansfield Center, CT

Natchaug Hospital Inc, situated in Mansfield Center, CT, offers thorough addiction recovery services for adults and adolescents dealing with co-occurring severe mental health disorders. This center provides intensive outpatient, outpatient, and day treatment programs, with expertise in anger management, brief intervention, and cognitive behavioral therapy. Natchaug Hospital Inc designs personalized treatment plans for active duty military, adult men, and women, guaranteeing individualized attention for everyone. Catering to both male and female individuals, the center's reliance on proven methods and commitment to excellent care position it as a leading option for individuals pursuing impactful rehabilitation.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)