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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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National Capital Trt and Recovery

Situated in Arlington, VA, National Capital Trt and Recovery delivers an extensive array of long-term residential treatment services designed for adult men facing challenges with substance abuse and concurrent mental health conditions. The center emphasizes personalized care using methods like 12-step support, anger management techniques, and short intervention strategies. Tailored programs are offered for individuals who have dealt with traumatic experiences, providing focused assistance for those requiring guidance. Committed to delivering exceptional care, this facility serves adults, seniors, and young adults in need of residential detoxification and round-the-clock support.

National Institutes of Health

The National Institutes of Health, situated in Bethesda, MD, delivers a complete spectrum of recovery solutions for adults and young adults. Their expertise encompasses detoxification, addressing substance use disorders, and managing co-occurring mental health conditions. This institution offers hospital-based inpatient services, ensuring constant, round-the-clock assistance. Their therapeutic interventions include facilitated engagement with the 12-step model, anger management training, and brief intervention techniques. The National Institutes of Health designs distinct programs for adult men, women, and survivors of intimate partner violence, demonstrating a commitment to addressing varied circumstances. By offering gender-specific care, they guarantee exceptional, personalized treatment for individuals pursuing freedom from addiction.

Native American Recovery Center

Situated in Phoenix, AZ, the Native American Recovery Center delivers exceptional treatment for substance use challenges for both adults and young adults. The facility is particularly adept at addressing co-occurring disorders that include substance use and significant mental health conditions, offering a variety of programs such as long-term residential, short-term residential, and 24-hour residential care. By employing methods like 12-step facilitation, anger management, and brief intervention, the center customizes its treatment plans to meet the unique needs of each individual. Committed to a personalized approach, the center ensures distinctive care for men and women alike. Those in search of a well-rounded and culturally attuned recovery journey will find the Native American Recovery Center to be a standout option, recognized for its high-quality services and varied program selection.

Natural State Recovery Centers
North Little Rock, AR

Natural State Recovery Centers in North Little Rock, AR, delivers a full spectrum of substance abuse treatment. Their offerings include inpatient detox and a variety of residential care options, providing continuous support or shorter program durations. Emphasizing personalized recovery, they employ methods like 12-step integration, emotional regulation training, and concise counseling. Natural State Recovery Centers serves individuals of all ages and genders. Their specialized interventions and custom treatment strategies position them as a strong option for individuals desiring effective and customized recovery.

Ness Center
Mandeville, LA

Ness Center, located in Mandeville, LA, offers a wide array of services aimed at helping individuals overcome addiction. This facility features options for detoxification, treatment for substance use disorders, and transitional living arrangements, including halfway houses and sober living environments. Ness Center provides various treatment modalities, such as intensive outpatient care, long-term residential stays, and outpatient therapy, ensuring that it meets the unique preferences and requirements of each client. The center is recognized for its expertise in 12-step programs, anger management, and brief intervention strategies. Additionally, Ness Center offers specialized programs for active duty military members, as well as targeted services for adult men and women. Catering to adults and young adults regardless of gender, Ness Center is committed to delivering personalized, high-quality care that fosters long-term recovery.

Nestled Recovery Center

Nestled Recovery Center, located in Las Vegas, NV, specializes in an array of addiction recovery services aimed at both adults and young adults. The center features extended residential programs, detoxification services available around the clock, and continuous medical supervision. Emphasizing 12-step methods, anger management strategies, and short-term interventions, this facility is designed for those facing dual challenges of substance dependence and significant mental health conditions. Additionally, there are specific programs designed for active military members, as well as separate offerings for adult men and women. Nestled Recovery Center is committed to providing personalized care, fostering a nurturing atmosphere conducive to healing and rehabilitation.

New Beginnings Recovery Center

At its Littleton, CO location, New Beginnings Recovery Center provides a full spectrum of care for those seeking to reclaim their lives from substance dependency. The center features hospital-level inpatient care, intensive outpatient programs, and supportive transitional living arrangements. Catering to a varied population, including active service members, adult men, and adult women, New Beginnings offers tailored treatment strategies. Their methods are grounded in scientific research and include components like 12-step integration, techniques for managing anger, and brief therapeutic interventions designed to meet specific challenges. This establishment is dedicated to offering personalized recovery pathways for both younger and adult individuals, with distinct programs available for men and women, ensuring each person receives dedicated assistance throughout their healing process.

New Beginnings Recovery Center LLC

New Beginnings Recovery Center LLC, situated in Seymour, IN, delivers tailored recovery programs for adults and young individuals facing addiction and co-occurring mental health challenges. Their offerings include intensive outpatient care, day treatment, and partial hospitalization, incorporating strategies like 12-step support, emotional regulation techniques, and brief counseling. The center features distinct programs designed for teens, adult men, and adult women, accommodating various demographics. New Beginnings Recovery Center LLC is committed to delivering excellent care and assistance to guide people toward sustained wellness.

Nebraska Urban Indian Health Coalition

The Nebraska Urban Indian Health Coalition, based in Omaha, NE, delivers extensive services for substance use disorders alongside tailored support for those facing dual mental health issues. Offering a variety of treatment formats, including long-term residential care and outpatient services with medication-assisted therapy, this center emphasizes 12-step programs, anger management techniques, and short-term interventions. It serves both adult men and women, as well as individuals who have undergone traumatic experiences. The facility is committed to providing personalized care and utilizes proven methods to foster successful recovery paths for adults and young adults of all backgrounds.

Never Alone Inc
Hurley, NY

Situated in Hurley, NY, Never Alone Inc provides extended residential and round-the-clock treatment services for adult men struggling with substance use. The facility emphasizes 12-step programs, anger management techniques, and brief intervention strategies. Specialized programs are available for teenagers, as well as for those who have faced issues related to intimate partner violence, domestic abuse, and sexual trauma. Never Alone Inc extends its services to children/adolescents, seniors, and young adults, promoting inclusive care for diverse age demographics. With a commitment to personalized and high-quality treatment, this center stands as a source of hope for individuals on their journey to recovery from addiction.

Native American Rehabilitation

Native American Rehabilitation, situated in Portland, OR, specializes in comprehensive, long-term residential and 24-hour care for adults of all genders grappling with substance use disorders. This includes specific support for survivors of intimate partner violence. The center employs a range of therapeutic modalities such as 12-step facilitation, anger management, and brief interventions to foster recovery. Their commitment to personalized treatment ensures that both adults and young adults receive the dedicated support necessary for lasting healing and comprehensive well-being.

National Capital Trt and Recovery

Situated in Arlington, VA, National Capital Trt and Recovery delivers focused outpatient programs for substance use rehabilitation, catering to both adults and young adults. The center employs proven techniques including brief intervention, cognitive behavioral therapy, and contingency management to create personalized care plans for each individual. With an inclusive approach for both male and female clients, the facility promotes a holistic treatment experience. National Capital Trt and Recovery distinguishes itself through its commitment to tailored treatment strategies and a nurturing atmosphere, making it a leading option for those in search of effective addiction recovery services in the region.

National Capital Trt and Recovery

National Capital Trt and Recovery, located in Arlington, VA, delivers an extensive array of services for those in need of addiction rehabilitation. This center specializes in detoxification, treatment for substance use disorders, and tailored support for adults with co-occurring mental health concerns or children experiencing emotional challenges. Offering various treatment modalities, including intensive outpatient and day treatment programs, it serves both adult and adolescent populations. The center employs diverse methodologies such as 12-step support, anger management techniques, and brief therapeutic interventions to guarantee customized and impactful care. Additionally, National Capital Trt and Recovery features distinct programs specifically designed for young individuals and provides gender-sensitive treatment options for both men and women, focusing on a comprehensive and personalized recovery journey.

New Beginnings Counseling and

At New Beginnings Counseling and in Lewiston, ID, we provide comprehensive outpatient services for substance use disorders. Our specialized programs address the unique needs of individuals facing co-occurring mental health and addiction challenges. Utilizing proven therapeutic methods like anger management, brief intervention, and cognitive behavioral therapy, our treatment is grounded in evidence-based practices. We offer distinct tracks for adolescents, adult men, and adult women, ensuring that care is specifically designed for each demographic. Our commitment extends to adults and seniors of all genders, with a focus on delivering personalized support and treatment. Discover a supportive environment at New Beginnings Counseling and dedicated to guiding you toward a successful recovery.

New Beginnings Counseling Centers

Situated in Las Vegas, NV, New Beginnings Counseling Centers delivers a variety of targeted addiction treatment options. The facility specializes in detoxification and treatment for substance use through various outpatient levels, including intensive outpatient and outpatient detox programs. Emphasizing relapse prevention, counseling for substance use disorders, and the use of telemedicine services, the center is dedicated to serving active duty military members as well as adult men and women. Catering to adults and young adults of all genders, New Beginnings Counseling Centers offers customized support and care to assist individuals in attaining sustainable recovery and embarking on a path to improved wellbeing.

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Navy Medicine Readiness Training Unit in Kittery, ME, delivers outpatient care for adults and young adults struggling with substance use. This center employs proven therapeutic methods like brief intervention, cognitive behavioral therapy, and motivational interviewing. Dedicated to providing excellent care, the unit serves active duty military and individuals experiencing co-occurring mental health and substance use challenges. Welcoming both men and women, the program customizes its approach to suit each person's specific requirements, offering thorough and impactful support for addiction recovery.

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Kirksey, KY

Neartown Inc in Kirksey, KY, provides personalized addiction recovery services for adult males within a secure and nurturing residential environment. This center excels in addressing dual diagnoses of substance use and severe mental health challenges, incorporating 12-step encouragement, emotional regulation training, and brief therapeutic interventions. Prioritizing active military members, adult men, and survivors of domestic abuse, the facility guarantees care that is specifically designed for each individual. Neartown Inc offers thorough assistance to seniors, young adults, and adult men through its short-term and around-the-clock residential care. Renowned for its superior services and unique treatment approaches, Neartown Inc is a leading option for individuals pursuing successful recovery.

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Situated in New York, NY, the Neighborhood Coalition for Shelter Inc delivers an extensive array of treatment options for substance use aimed at both adults and young adults. This center is dedicated to assisting those with simultaneous substance use issues and significant mental health challenges. Treatment includes intensive outpatient care, outpatient services, and options for methadone/buprenorphine or naltrexone in an outpatient setting. The facility employs evidence-based methods such as anger management, brief interventions, and cognitive behavioral therapy. Offering specialized programs designed for adult men, adult women, and individuals with trauma backgrounds, this center emphasizes personalized care to address varying requirements. It serves both male and female clients in need of effective rehabilitation support.

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Hazel Park, MI

Situated in Hazel Park, MI, Neu Hope stands as a premier rehabilitation facility providing outpatient services for substance abuse. They specialize in concurrent treatment for individuals facing both addiction and significant mental health challenges, encompassing emotional disturbances in youth and adults. Neu Hope equips clients with relapse prevention techniques and offers dedicated counseling for substance use disorders. Their personalized programs are designed for active military members, teenagers, and adult men. The center utilizes outpatient pharmacological interventions such as methadone, buprenorphine, and naltrexone, serving adult men and women who require thorough, high-standard care.

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New Albany Community Medical Services, located in New Albany, IN, provides extensive outpatient care for adults battling substance abuse and co-occurring mental health issues, alongside support for children experiencing emotional disturbances. This establishment features personalized treatment plans, incorporating 12-step facilitation, brief interventions, and cognitive behavioral therapy. Catering to all genders across adult and child populations, the facility offers medication-assisted treatment options like methadone, buprenorphine, or naltrexone, in addition to standard outpatient services. New Albany Community Medical Services prioritizes a tailored approach to deliver superior care for individuals confronting addiction and mental wellness concerns.

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Buffalo, NY

New Alternatives, situated in Buffalo, NY, specializes in outpatient treatment for substance use in adults and young adults who are also dealing with mental health issues. The center delivers targeted care through various methods, including anger management techniques, cognitive behavioral therapy, and short-term interventions. With a focus on individuals who have a history of trauma or co-occurring conditions, including those involved in the legal system, New Alternatives is committed to providing inclusive support for all individuals. Their outpatient services include methadone, buprenorphine, and naltrexone treatments, as well as ongoing outpatient support, all aimed at personalized recovery. Clients will receive high-quality, evidence-informed care at this center, which is dedicated to fostering healing and overall wellness.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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