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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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New Day Treatment Center LLC

New Day Treatment Center LLC, located in Far Rockaway, NY, provides a variety of science-supported treatment programs targeting substance abuse and co-occurring mental health issues. The center features intensive outpatient, outpatient, and standard outpatient options designed specifically for both adults and young adults. There are specialized programs catering to adult men, women, and those who have been affected by domestic or intimate partner violence. Emphasizing 12-step support, anger management, and short interventions, this center ensures all-encompassing care within a nurturing atmosphere. Committed to serving both male and female individuals, New Day Treatment Center LLC focuses on delivering high-quality, personalized treatment for those on the path to recovery.

New Directions Behavioral Health Ctr

New Directions Behavioral Health Ctr, located in Newark, NJ, specializes in providing targeted treatment programs for both adults and young adults dealing with substance use issues. Emphasizing intensive outpatient services, outpatient care, and day treatment/partial hospitalization, the center offers personalized treatment plans to meet each individual's specific requirements. The facility employs various methods, including 12-step programs, anger management, and short intervention techniques, making it suitable for individuals facing both mental health and substance use challenges. With specially designed programs for men and women, the center fosters an inclusive and supportive atmosphere. Dedicated to delivering high-quality care, the diverse range of treatment services and gender-focused programs position the center as an essential option for those pursuing effective solutions for addiction recovery.

New Directions Inc
Cleveland, OH

New Directions Inc in Cleveland, OH, provides extensive support for individuals of all ages struggling with addiction and related mental health challenges. Their diverse treatment plans encompass intensive outpatient care, extended residential stays, and standard outpatient services, accommodating clients at every point in their recovery journey. Dedicated programs are available for teenagers, those who have experienced trauma, and individuals managing multiple diagnoses, guaranteeing personalized attention. By employing methods like 12-step support, emotional regulation techniques, and concise therapeutic interventions, the facility delivers effective treatment centered on each person's unique requirements. Serving both men and women, New Directions Inc is committed to helping clients achieve sustained well-being.

New Directions Inc
Cleveland, OH

New Directions Inc, situated in Cleveland, OH, delivers extensive rehabilitation solutions. They offer robust outpatient, extended stay residential, and outpatient therapy for addiction, co-occurring mental health issues, and childhood emotional challenges. Focusing on specific groups like teens, trauma victims, and those with dual diagnoses, New Directions Inc customizes its 12-step assistance, anger resolution, and brief intervention methods for every individual's distinct requirements. Serving adults and young people across all genders, the facility provides excellent support within transitional living, halfway housing, and sober residences. For anyone needing kind and successful recovery, New Directions Inc is a guiding light of optimism and recovery.

New England Medical Group LLC

New England Medical Group LLC, situated in Hingham, MA, provides targeted addiction recovery services for adults and young adults. Their offerings include intensive outpatient, outpatient, and partial hospitalization programs. Emphasizing a personalized approach, the center employs methods like 12-step facilitation, anger management, and brief intervention. Catering to distinct needs of male and female individuals, New England Medical Group LLC is recognized for its dedication to high-standard care and customized treatment paths. For those in search of thorough and successful addiction treatment, this facility is committed to aiding the path to sobriety.

New Era Rehabilitation Center Inc

New Era Rehabilitation Center Inc, located in Bridgeport, CT, delivers an extensive array of services for addiction recovery. The center specializes in detoxification and treatment for substance use disorders, including tailored support for those facing both substance-related issues and significant mental health challenges. Treatment options are available in various formats such as intensive outpatient, outpatient, and day treatment, accommodating adults and young adults across all gender identities. By prioritizing methods like 12-step facilitation, anger management, and brief intervention sessions, they guarantee individualized care for every client. Additionally, distinctive programs for active duty military members, as well as for adult men and women, further elevate the standard of care at this esteemed rehabilitation facility.

New Era Rehabilitation Center Inc

New Era Rehabilitation Center Inc, located in New Haven, CT, provides an extensive array of specialized services aimed at treating addiction for both adults and young adults. The facility offers detox services, treatment for substance use disorders, and customized programs for those struggling with both substance abuse and severe mental health conditions. With an emphasis on intensive outpatient treatment and daytime outpatient programs, New Era Rehabilitation Center Inc uses proven methods, such as 12-step facilitation and anger management techniques. The center also features specialized programs for active military personnel and separately accommodates adult men and women, ensuring personalized care and support for individuals on their path to recovery.

New Found Life
Long Beach, CA

New Found Life, situated in Long Beach, CA, features a variety of customized treatment options designed for those facing addiction and related mental health challenges. The center provides long-term, short-term, and 24/7 residential care. By incorporating proven methods such as 12-step programs, anger management therapy, and brief interventions, New Found Life specifically supports adult women dealing with co-occurring conditions. Catering to adults of all ages, including seniors and younger individuals, this facility emphasizes high-quality care within a nurturing atmosphere. If you are looking for thorough and individualized treatment in a women-only environment, this center could be the perfect fit for your recovery path.

New Found Life
Long Beach, CA

New Found Life in Long Beach, CA, is a specialized treatment center for adult men grappling with addiction and co-occurring mental health challenges. They provide diverse program lengths, from short-term to extended residential stays, all within a 24-hour monitored environment. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies. New Found Life is particularly adept at serving adults, seniors, and young adults, with a distinct emphasis on integrated care for those facing dual diagnoses. Their commitment lies in offering tailored, gender-specific care designed to foster enduring recovery for their male clientele.

New Found Life
Long Beach, CA

New Found Life, situated in Long Beach, CA, provides extensive addiction recovery services for adults and young adults struggling with co-occurring mental health issues. Their programs include intensive outpatient, outpatient, and day treatment, incorporating 12-step facilitation, anger management, and brief intervention strategies. They offer specialized care through programs designed for adult men, women, and individuals with dual diagnoses. New Found Life prioritizes personalized treatment plans and evidence-based methods to guide clients toward sustained sobriety. The facility fosters a supportive setting for recovery and personal development, with an emphasis on services that are gender-specific and age-appropriate.

New Found Life
Long Beach, CA

New Found Life, situated in Long Beach, CA, is a leading addiction treatment facility committed to helping individuals overcome substance abuse. They provide a range of residential programs, including extended, brief, and immediate care, specifically designed for adult men dealing with co-occurring mental health conditions. Their treatment approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies, serving adults of all ages, including seniors and young adults. New Found Life distinguishes itself with its dedicated programs for those facing both addiction and mental health challenges, offering personalized care plans. Discover exceptional treatment and recovery support at this center focused on enabling enduring sobriety.

New Directions Healthcare

New Directions Healthcare, located in Erie, PA, provides outpatient programs for substance use treatment specifically designed for both adults and young adults. Their array of services features outpatient treatment options with methadone, buprenorphine, or naltrexone, along with support for 12-step participation, anger management classes, and brief therapeutic interventions. The center serves a diverse clientele that includes active duty service members, as well as adult males and females, ensuring personalized care for different genders and age categories. With an emphasis on quality and research-supported methods, New Directions Healthcare is committed to guiding individuals through their recovery process with empathy and professionalism.

New Focus Addiction and

New Focus Addiction is dedicated to providing thorough substance use treatment for adults who face serious mental health challenges, as well as for children dealing with significant emotional issues. The center offers a range of outpatient services, including treatments like methadone, buprenorphine, or naltrexone, employing strategies such as 12-step programs, anger management techniques, and brief interventions. There are specialized programs designed for active military members, adolescents, and adult males. Catering to adults, children, adolescents, and seniors across all genders, this center prioritizes individualized care. With its commitment to high-quality service and specialized care options, it stands out as a commendable choice for those in need of effective and customized addiction treatment.

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New Destiny Treatment Center in Clinton, OH provides extensive support for addiction recovery. Their services encompass detoxification, broader substance use interventions, and targeted assistance for adults with dual diagnoses of substance use and severe mental health conditions, as well as children with serious emotional challenges. Offering various levels of care like intensive outpatient, extended residential stays, and standard outpatient programs, New Destiny Treatment Center serves adult men and women, including survivors of domestic or intimate partner abuse. Employing methods like 12-step facilitation, anger management techniques, and brief intervention strategies, the center is dedicated to delivering high-quality treatment to adults and young adults, regardless of gender.

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Situated in Rose Hill, NC, New Dimension Group LLC specializes in extensive substance use rehabilitation for adults, including those facing significant mental health disorders alongside addiction. The center features intensive outpatient services, outpatient programs, and standard outpatient options. It also offers tailored programs for active duty military personnel, teenagers, and adult males, accommodating a wide range of ages and gender needs. By employing methods like 12-step facilitation, anger management, and brief interventions, this facility emphasizes personalized care and evidence-driven approaches. Clients looking to address substance use or dual diagnoses can anticipate high-quality treatment customized to their specific requirements at New Dimension Group LLC.

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New Directions Counseling, located in Billings, MT, provides extensive treatment for substance use disorders aimed at both adults and seniors. The center features specialized programs catering to adult women and clients involved in the criminal justice system, offering personalized services to address a wide range of needs. Treatment options include intensive outpatient, outpatient, and standard outpatient formats. By employing evidence-based strategies like brief interventions, cognitive behavioral therapy, and the Matrix Model, the facility guarantees high-quality care for clients of all genders. If you or someone you know is in need of effective addiction recovery services that emphasize personalized care and evidenced therapeutic methods, New Directions Counseling stands out as an essential resource in the Billings community.

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New Directions Substance Use Treatment in Brooklyn, NY, provides personalized outpatient programs for individuals pursuing sobriety. The facility utilizes targeted interventions including anger management, brief intervention, and cognitive behavioral therapy. Serving adolescents, adult men, and adult women, they offer support for both young people and adults, with services available to all genders. Their offerings include outpatient treatment with methadone/buprenorphine or naltrexone, alongside general outpatient services, ensuring thorough support for those facing substance use challenges. This center is dedicated to delivering high-quality, individualized care, standing as a significant resource for effective addiction recovery.

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New Directions Treatment Services located in Bethlehem, PA, provides a wide array of treatment options for substance use, including outpatient programs, outpatient methadone/buprenorphine, and naltrexone treatments. The center employs a variety of methods, such as 12-step facilitation, anger management, and brief intervention techniques to tackle issues related to addiction. It features specialized programs designed for adult men, adult women, and pregnant or postpartum women, ensuring a comprehensive approach for a diverse clientele. New Directions Treatment Services supports both adults and young adults of any gender, offering personalized care aimed at fostering long-term recovery. Committed to delivering high-quality, evidence-based services, this facility seeks to assist clients on their paths to a sober life.

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New Directions Treatment Services in Reading, PA, provides extensive outpatient care for individuals struggling with addiction and co-occurring mental health conditions. Their specialized programs are designed for adult men, adult women, and pregnant or postpartum women, offering individualized treatment plans. Utilizing methods such as 12-step support, anger management techniques, and brief intervention strategies, the center emphasizes a complete approach to recovery. They offer various outpatient options, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, all delivered with a commitment to fostering sustained sobriety for both male and female clients.

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Canterbury, NH

New Freedom Academy, situated in Canterbury, NH, delivers tailored therapeutic interventions for individuals grappling with addiction and dual diagnoses. The facility offers comprehensive care through intensive outpatient, extended residential stays, and outpatient programs, employing proven methods such as 12-step support, emotional regulation training, and short-term counseling. Specifically designed tracks are available for military personnel, adult men, and adult women. Prioritizing personalized recovery journeys, New Freedom Academy welcomes all genders, providing thorough and customized rehabilitation in a nurturing setting.

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Situated in Bonney Lake, WA, New Freedom Recovery Center LLC provides a wide array of substance abuse treatment programs. The facility features intensive outpatient, outpatient, and standard outpatient options tailored for adults and seniors. It also offers specialized programs for various groups including active duty military, adolescents, and adult men, addressing unique needs across demographics. Employing a variety of methods such as 12-step facilitation, anger management, and brief interventions, New Freedom Recovery Center LLC prioritizes personalized care. Catering to both male and female clients, the center is dedicated to delivering effective, evidence-based treatment that supports individuals throughout their recovery process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)