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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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New Hope Recovery

New Hope Recovery, situated in Modesto, CA, delivers a full spectrum of addiction treatment. They offer detox, substance use treatment, transitional housing, and sober living for adults and young adults in a nurturing setting. Their programs include intensive outpatient, long-term residential, and outpatient options. New Hope Recovery emphasizes personalized care, utilizing methods like 12-step facilitation, anger management, and brief interventions. The facility provides distinct programs for men and women, ensuring a customized recovery journey. Opt for New Hope Recovery for excellent treatment and a unique route to lasting sobriety.

New Horizons Medical

New Horizons Medical, situated in Quincy, MA, delivers extensive outpatient care tailored for adults and young adults battling substance use disorders. This facility addresses the complexities of co-occurring substance use and significant mental health conditions in adults, as well as serious emotional disturbances in children. They offer targeted programs for active duty military personnel, adult men, and adult women, demonstrating a commitment to serving a broad spectrum of individuals. Employing methods like 12-step facilitation, anger management, and brief intervention, New Horizons Medical prioritizes individualized treatment plans. Their outpatient services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care, highlighting the high standard and efficacy of their programs for all clients.

New Hope Ranch

New Hope Ranch, situated in Manor, TX, is a distinguished center providing extensive care for adult men dealing with addiction and underlying mental health conditions. They offer hospital-based inpatient detox and specialized therapeutic programs, including 12-step support and anger management techniques. A key feature of New Hope Ranch is its dedicated support for men who have endured intimate partner, domestic, or sexual abuse. Catering to adults, seniors, and young adults, the center fosters a nurturing atmosphere for male individuals pursuing freedom from substance dependence and mental health struggles.

New Horizons Medical
Framingham, MA

Situated in Framingham, MA, New Horizons Medical is dedicated to delivering extensive outpatient services for individuals dealing with substance use and accompanying mental health challenges. The center has a particular emphasis on supporting adults grappling with significant emotional upheaval and mental disorders. Available treatment options encompass outpatient modalities like methadone, buprenorphine, and naltrexone, alongside regular outpatient programs. By focusing on approaches such as 12-step support, anger management, and short-term interventions, New Horizons Medical customizes its care for active military members and both adult men and women. This establishment caters to adults and young adults across all gender identities, striving to offer exceptional, personalized support aimed at fostering sustainable recovery.

New Horizons Medical Inc

Located in Brookline, MA, New Horizons Medical Inc delivers extensive outpatient services for adults facing substance use disorders alongside serious mental health challenges, as well as addressing emotional issues in children. The center features tailored programs for military active duty members, and focuses on adult men and women, accommodating a wide variety of age ranges including young adults. Emphasizing 12-step principles, anger management strategies, and brief intervention techniques, New Horizons Medical Inc is committed to providing personalized care that meets individual requirements. Whether individuals are looking for outpatient methadone/buprenorphine therapy or standard outpatient options, this facility fosters a nurturing atmosphere for clients of all genders on their path to recovery.

New Horizons Medical

New Horizons Medical, situated in Lynn, MA, provides outpatient services for adults and adolescents struggling with substance use. The center excels in addressing co-occurring substance use disorders and significant mental health challenges in adults, as well as serious emotional disturbances in children. Their approach emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies to deliver personalized treatment. Specialized programs are offered for active duty military members, adult men, and adult women. New Horizons Medical also delivers outpatient treatment utilizing methadone, buprenorphine, or naltrexone, ensuring comprehensive support for all clients on their path to recovery.

New Hope Integrated Behavioral Health

New Hope Integrated Behavioral Health, situated in Long Branch, NJ, is dedicated to offering a well-rounded array of services tailored for adult women aiming to overcome challenges related to substance use and concurrent mental health issues. This center features long-term residential options that emphasize 12-step programs, cognitive behavioral therapy, and contingency management techniques. It specializes in assisting individuals who have undergone intimate partner violence, domestic abuse, and sexual trauma, serving a diverse clientele including adults, seniors, and young adults in a nurturing and secure setting. With a focus on gender-specific treatment, New Hope Integrated Behavioral Health is committed to providing exceptional, personalized care to guide clients towards sustainable recovery and improved mental health.

New Hope Integrated Behavioral Health

Situated in Asbury Park, NJ, New Hope Integrated Behavioral Health delivers extensive long-term residential care for individuals dealing with substance use issues alongside mental health challenges. This center emphasizes transitional housing and sober living solutions. It employs methods such as 12-step programs, cognitive behavioral therapy, and contingency management, specifically designed for adult women who have faced situations of intimate partner violence, domestic abuse, and sexual assault. Catering to adults, including seniors and young adults, the center fosters a nurturing and secure atmosphere for women aiming to heal from addiction and past traumas.

New Hope Integrated Behavioral Health

Situated in Marlboro, NJ, New Hope Integrated Behavioral Health presents an extensive array of recovery services for both adults and young adults grappling with addiction. The center specializes in detoxification, substance use treatment, and the management of co-occurring conditions within a residential framework. By employing customized strategies including 12-step facilitation, cognitive-behavioral therapy, and contingency management, this facility guarantees personalized attention. Specific programs are designed for adult men, adult women, and those who have faced intimate partner violence. New Hope Integrated Behavioral Health is committed to offering quality support, emphasizing recovery and well-being in a nurturing environment for individuals on their healing journey.

New Hope Integrated Behavioral Health

New Hope Integrated Behavioral Health, situated in Long Branch, NJ, specializes in rehabilitation services for adult males confronting substance use issues alongside severe mental health challenges. The facility offers a range of treatment options, including intensive outpatient care, long-term residential programs, and outpatient services, all grounded in evidence-based methodologies like cognitive behavioral therapy and 12-step support. With an emphasis on individuals who have faced intimate partner violence, sexual abuse, and domestic abuse, this center provides a secure and nurturing environment conducive to recovery. Customized programs for seniors, young adults, and other adults guarantee that each person's care is specifically tailored to their needs. Begin your journey towards recovery and sobriety at New Hope Integrated Behavioral Health.

New Hope Integrated Behavioral Health

New Hope Integrated Behavioral Health, situated in Marlboro, NJ, is a dedicated facility providing thorough addiction recovery solutions. They excel in detox, addressing substance dependencies, and managing dual diagnoses. Offering both inpatient and brief care options, their services are available for individuals of all ages. Their approach incorporates 12-step guidance, cognitive behavioral strategies, and motivational rewards, with each care plan customized for personal requirements. Distinctive offerings for teens, victims of domestic abuse, and those who have experienced sexual trauma distinguish this center. New Hope Integrated Behavioral Health accommodates both male and female individuals, guaranteeing superior support for anyone on their journey to wellness.

New Hope Integrated Behavioral Health

New Hope Integrated Behavioral Health, situated in Asbury Park, NJ, delivers a complete spectrum of recovery support for adults and emerging adults. Their expertise lies in addressing addiction and dual diagnoses, offering tiered treatment intensities from intensive outpatient to standard outpatient care. Employing scientifically validated methods like cognitive behavioral therapy and contingency management, New Hope serves a broad array of individual requirements. Distinctive services tailored for adult women and those impacted by intimate partner violence, domestic abuse, or sexual trauma distinguish this establishment. Committed to superior treatment and personalized recovery strategies, New Hope Integrated Behavioral Health is devoted to aiding individuals in their path to wellness.

New Hope CORPS
Homestead, FL

In Homestead, Florida, New Hope CORPS delivers a complete spectrum of recovery support for individuals addressing substance dependence, dual diagnoses, and experiences of trauma. This center features intensive outpatient, extended residential stays, and outpatient services, all grounded in proven therapeutic methods like 12-step integration, cognitive behavioral therapy, and strategies for managing anger. New Hope CORPS has a particular expertise in supporting adult men and individuals affected by domestic violence, intimate partner abuse, or sexual assault. Concentrating on adults and young adults, the center offers individualized care to both male and female patients, fostering an environment of encouragement and acceptance for everyone on their path to healing.

New Horizons Medical

New Horizons Medical, situated in Haverhill, MA, provides extensive and tailored recovery programs. This center delivers outpatient care for adults dealing with addiction and co-occurring severe mental health conditions, as well as for children experiencing significant emotional distress. Their offerings encompass 12-step support, techniques for managing anger, and short-term therapeutic interventions. New Horizons Medical also features distinct programs designed for active military personnel, adult men, and adult women, accommodating a broad spectrum of needs. They are dedicated to providing high-quality, individualized care for adults and young adults of all genders, guiding each person toward lasting recovery.

New Hope Manor Inc
Barryville, NY

Situated in Barryville, NY, New Hope Manor Inc delivers an array of specialized rehabilitation services. This center features long-term residential care, detoxification support, and round-the-clock residential assistance. Emphasizing 12-step methodologies, anger management, and brief intervention strategies, the facility caters to a diverse clientele. Programs are specifically designed for adolescents, adult women, and individuals affected by intimate partner violence, providing thorough support for women, children, and older adults facing substance use and concurrent mental health challenges. New Hope Manor Inc prides itself on personalized care and high-quality treatment, making it an essential option for individuals on their path to recovery.

New Horizon Care Centers

New Horizon Care Centers located in Spokane, WA, provides extensive long-term residential treatment options for adult women and seniors dealing with substance use disorders and co-existing mental health challenges. The program features strategies such as 12-step facilitation, anger management, and brief intervention techniques. This center is particularly skilled in assisting female clients, including those who have encountered intimate partner violence, domestic abuse, and sexual trauma. Emphasizing transitional housing and sober living scenarios, New Horizon Care Centers is committed to delivering effective treatment in a nurturing and secure environment that caters to the individual needs of every client.

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Fallon, NV

Nestled in Fallon, NV, New Frontier provides a complete spectrum of care for those battling addiction. Their offerings include detox, substance abuse counseling, transitional living, and supportive sober living environments. Whether you require intensive outpatient services, long-term residential care, or standard outpatient programs, New Frontier accommodates different recovery paths. They are adept at 12-step facilitation, anger management, and brief intervention techniques. Specialized programs are in place for active military personnel, teenagers, and adult men. New Frontier is dedicated to serving adults and seniors, regardless of gender, with a commitment to personalized treatment strategies designed for each individual's unique journey.

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"New Hope Health Services, located in Washington, DC, provides an extensive array of addiction recovery programs for both adults and youth. This center offers intensive outpatient services, standard outpatient care, and partial hospitalization programs. Emphasizing 12-step support, anger management strategies, and brief interventions, the facility targets those facing dual challenges of substance use and significant mental health conditions. It features specialized programs for active military personnel, teenagers, and adult males. With services for all genders, New Hope Health Services is committed to delivering exceptional care to facilitate enduring recovery."

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New Hope Integrated Behavioral Health, located in Freehold, NJ, provides extensive treatment for substance abuse alongside specialized support for those facing serious mental health challenges. The center features both intensive outpatient and outpatient services, which include treatment options such as methadone/buprenorphine and naltrexone. Employing proven methods like cognitive behavioral therapy and motivational interviewing, this facility customizes treatment plans to meet the unique needs of each patient. Additionally, there are specific programs designed for active military personnel, teenagers, and adult males. Catering to a diverse population that includes adults, children, adolescents, and seniors of any gender, New Hope Integrated Behavioral Health emphasizes quality care aimed at promoting sustainable recovery and overall wellness.

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Muscatine, IA

Situated in Muscatine, IA, New Horizons stands out as a prominent rehabilitation facility focused on treating substance use disorders in both adults and young adults. The center offers a range of services, including intensive outpatient treatment, outpatient care, and standard outpatient programs. It employs personalized treatment methods such as brief intervention, motivational interviewing, and relapse prevention strategies. New Horizons prioritizes customized programs to create a nurturing and holistic atmosphere for clients of all genders. Committed to delivering high-quality support, this center aims to assist individuals in starting their path to recovery and fresh starts.

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Situated in Stuart, Florida, New Horizons of the Treasure Coast provides extensive treatment for substance use disorders in both adults and children who also face severe mental health challenges. This center offers outpatient services along with methadone, buprenorphine, and naltrexone therapies, incorporating techniques like cognitive behavioral therapy and anger management. New Horizons features specialized programs geared towards active military personnel, teenagers, and adult males, making it accessible to a broad spectrum of individuals. Their commitment to quality care addresses the specific needs of both male and female adults as well as children and adolescents.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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