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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Nexstep Medical Detox

Nexstep Medical Detox, situated in Orem, UT, delivers thorough substance withdrawal and addiction treatment within a hospital inpatient environment. This facility specializes in care that includes 12-step support, addiction counseling, and remote therapy options. Nexstep offers customized treatment for active military personnel, adult men, and adult women, accommodating both adult and young adult individuals. Their programs are designed with gender-specific approaches for men and women. Clients can anticipate excellent care and assistance throughout their path to healing at Nexstep.

Next Door Inc
Nashville, TN

Next Door Inc, located in Nashville, TN, is dedicated to providing specialized recovery programs for adult women facing addiction. They offer comprehensive treatment pathways, including intensive outpatient care, day treatment programs, and partial hospitalization. Employing proven therapeutic methods like 12-step support, anger management techniques, and brief intervention strategies, Next Door Inc effectively addresses the complex needs of individuals with dual diagnoses of mental health and substance use disorders. The center emphasizes a trauma-informed approach, fostering a secure and encouraging atmosphere for adults, seniors, and young adults committed to their sobriety journey. Next Door Inc distinguishes itself through personalized treatment plans and a steadfast dedication to high-quality support for those seeking lasting recovery.

Next Level Recovery

Situated in Midvale, UT, Next Level Recovery provides an extensive array of rehabilitation services. This center focuses on detoxification, addiction treatment, and tailored support for individuals dealing with both substance use issues and significant mental health disorders. The treatment options available include intensive outpatient programs, outpatient services, and partial hospitalization. Next Level Recovery employs proven methods such as 12-step programs, anger management strategies, and brief counseling sessions. The facility also offers specialized programs designed for active duty military members, adolescents, and adult males, accommodating a wide spectrum of clients. Catering to both adults and youth, Next Level Recovery prioritizes personalized care for all clients, offering high-quality support for those aiming to conquer addiction and mental health difficulties.

Next Wind LLC
Englewood, NJ

Next Wind LLC, located in Englewood, NJ, provides thorough substance abuse therapies and temporary living accommodations for adults and young adults. Their day treatment and intensive outpatient services utilize 12-step guidance, emotional regulation skills, and short-term intervention methods. This establishment offers tailored support for adult men and women, including those affected by domestic abuse. Emphasizing personalized treatment plans, Next Wind LLC serves both male and female individuals within a nurturing setting. For those looking for a recovery center committed to excellent service and complete well-being, Next Wind LLC is a strong choice.

Nexus Recovery Center Inc

Nexus Recovery Center Inc, located in Dallas, TX, delivers a wide array of addiction treatment options focused on adult women. The facility offers services including detox, intensive outpatient care, and extended residential programs. With techniques such as 12-step support, anger management, and focused interventions, Nexus Recovery Center Inc is adept at helping individuals who have faced trauma, as well as those dealing with simultaneous mental health and substance abuse issues. The center's programs are designed for various age groups, including adults, seniors, and younger adults, ensuring personalized treatment and attention for every client. If you or someone you know is in need of quality rehabilitation services in a supportive, gender-specific setting, Nexus Recovery Center Inc is a reliable option.

Newton Medical Center

Newton Medical Center, located in Newton, NJ, provides extensive outpatient care for individuals dealing with substance use disorders, concurrent mental health conditions, and emotional challenges. The center features targeted programs designed for adult men, women, and clients facing dual diagnoses. Treatment options encompass 12-step support, brief interventions, and cognitive behavioral therapy, customized for both adult and adolescent clients of any gender. With options for outpatient day programs and methadone/buprenorphine treatments, the facility prioritizes tailored care meeting the distinct requirements of each individual. Newton Medical Center is distinguished by its commitment to evidence-based practices and high standards of personalized rehabilitation services.

Nimiipuu Behavioral Health

Nimiipuu Behavioral Health, located in Lapwai, ID, provides outpatient care for adults dealing with substance use issues alongside significant mental health challenges. The center employs a variety of treatment modalities including 12-step support, anger management, and brief interventions. They also have tailored programs for active military members, teenagers, and adult males. Services are inclusive for both adults and older adults, offering treatment for individuals of all genders. Committed to delivering high-quality care, this center focuses on specialized programs designed to assist different populations in their recovery journey.

Newport Integrated

Newport Integrated, situated in Decatur, GA, delivers thorough care for those confronting addiction and accompanying mental health challenges. Their inpatient detox and treatment options are available for adults and seniors, featuring distinct programs for active military personnel, teenagers, and adult men. The facility utilizes scientifically-backed methods such as 12-step facilitation, anger management techniques, and brief therapeutic interventions. Committed to high standards of care, Newport Integrated fosters a nurturing atmosphere for all clients, regardless of gender, on their journey to recovery. For tailored and successful addiction treatment, this establishment is devoted to guiding you toward sustained abstinence.

Niagara Co Dept of MH Services

Niagara Co Dept of MH Services, located in Niagara Falls, NY, provides extensive treatment options for substance use disorders in both adults and children who are facing significant mental health issues. The center offers outpatient care such as methadone, buprenorphine, and naltrexone therapies, delivering personalized treatment through approaches like anger management, cognitive behavioral therapy, and brief intervention strategies. Programs are customized for each gender, emphasizing a personalized methodology to ensure successful rehabilitation outcomes. With a focus on emotional issues in children and severe mental health conditions in adults, this center is committed to offering exceptional care for individuals dealing with addiction and mental health concerns.

Nimiipuu Health Clinic

Nimiipuu Health Clinic, located in Kamiah, ID, delivers outpatient services for adults dealing with substance use issues alongside significant mental health disorders or emotional challenges in children. The clinic employs a structured outpatient program that includes 12-step support, anger management strategies, and brief therapeutic interventions. There are specialized offerings for active military members, teenagers, and adult males. The facility serves adults and seniors across all genders, emphasizing personalized treatment plans and proven methodologies to guarantee effective care for individuals pursuing recovery from addiction and related conditions.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers targeted outpatient care for individuals dealing with substance abuse as well as accompanying mental health issues among both adults and youth. The facility offers a variety of services such as outpatient methadone/buprenorphine or naltrexone treatment, anger management, brief intervention, and cognitive behavioral therapy. It is particularly focused on assisting trauma survivors and those with dual diagnoses, providing care for both male and female patients in a nurturing setting. Whether needing support for substance use, significant mental health challenges, or emotional issues, Newport Mental Health presents extensive programs designed to address unique requirements and foster enduring recovery.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers an extensive variety of outpatient services aimed at addressing substance use and concurrent mental health challenges for both adults and children. The center specializes in various therapeutic approaches, including anger management, cognitive behavioral therapy, and trauma-informed care. Committed to providing high-quality support, Newport Mental Health customizes treatment strategies to cater to the unique requirements of each client, particularly those facing both mental health and substance use issues. The facility accommodates adults and young adults, offering treatment options that are specific to gender. Whether in need of routine outpatient services or medication-assisted treatments like methadone or buprenorphine, clients can expect individualized support and care at Newport Mental Health.

Newport Mental Health
Middletown, RI

Newport Mental Health, situated in Middletown, RI, delivers extensive outpatient care for addiction and co-occurring psychological issues. The facility offers dedicated support for adults and young individuals experiencing significant emotional distress. Therapeutic methods employed encompass anger resolution, timely interventions, and cognitive-behavioral strategies. Distinct programs are available for teenagers, survivors of trauma, and those with integrated mental health and substance abuse challenges. Committed to high standards, Newport Mental Health crafts individualized recovery paths for all genders.

Next Step Treatment Center

Next Step Treatment Center, situated in Baltimore, Maryland, focuses on providing tailored substance use treatment for adult clients who also grapple with significant mental health disorders. This center features both intensive outpatient and outpatient services, incorporating treatment options such as methadone and buprenorphine. Emphasizing approaches like 12-step facilitation, anger management, and brief intervention, it serves both men and women, including senior adult clients. Additionally, specialized programs are designed for adolescents, adult males, and adult females. Committed to offering exceptional care, Next Step Treatment Center aims to support individuals in advancing towards their recovery journey.

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At Next Step Recovery Center in Columbus, OH, we provide a complete suite of services for adults and young adults grappling with addiction. Our offerings encompass intensive outpatient care, extended residential stays, and flexible outpatient plans, accessible to individuals of all genders. We employ specialized therapies like anger management, cognitive behavioral therapy, and trauma-informed approaches to personalize each client's journey. Beyond treatment, we offer transitional housing and sober living environments. Notably, we have distinct programs designed for those affected by sexual abuse or trauma. Next Step Recovery Center is committed to high-quality, personalized care, serving as a vital resource for those pursuing lasting sobriety.

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College Park, MD

Situated in College Park, MD, Nimel Mental Health delivers focused substance abuse treatment for adults dealing with significant mental health issues alongside their addiction, as well as for children experiencing severe emotional problems. The facility offers various outpatient services, such as intensive outpatient programs and day treatment, ensuring personalized support through methods like 12-step facilitation and anger management. Nimel Mental Health serves active military members, teenagers, and adult males, providing services for both men and women. What distinguishes Nimel Mental Health is its wide-ranging programs designed for specific demographics, guaranteeing exceptional care for anyone looking to overcome substance use and mental health difficulties.

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The Norfolk Community Services Board, situated in Norfolk, VA, delivers expert care for addiction, dual diagnoses, and severe mental health challenges affecting adults, alongside addressing emotional issues in youngsters. This institution offers intensive outpatient services, standard outpatient programs, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, anger management techniques, and short-term therapeutic strategies, the center serves adults and young adults irrespective of gender. Special programming is provided for individuals with a history of trauma, those living with HIV/AIDS, and expectant or new mothers. The center's individualized methodology and thorough support systems establish it as a crucial provider for effective recovery.

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Havre de Grace, MD

Norkris Services Inc, situated in Havre de Grace, MD, provides extensive outpatient care for adults facing substance abuse and concurrent mental health disorders, as well as children with significant emotional challenges. The center implements customized programs for individuals, employing research-supported methods such as cognitive behavioral therapy and motivational techniques. Emphasizing individualized attention, this facility caters to adults and seniors of all genders. Clients seeking ongoing outpatient services or therapies involving methadone, buprenorphine, or naltrexone can anticipate exceptional care and assistance at Norkris Services Inc.

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North Central Human Service Center, situated in Minot, ND, delivers a complete spectrum of addiction recovery support. They offer detox, substance abuse treatment, and focused assistance for those facing both addiction and significant mental health challenges. Their offerings include intensive outpatient programs, day treatment, and standard outpatient care. The center employs proven therapeutic methods like anger management, brief counseling, and cognitive behavioral therapy. Tailored programs are available for young people and individuals with co-occurring mental health conditions. Serving adults and seniors without regard to gender, North Central Human Service Center is dedicated to providing excellent, personalized treatment.

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The North Central MO Mental Health Center, located in Chillicothe, MO, specializes in offering outpatient services aimed at addressing substance use disorders along with co-occurring mental health issues for both adults and children. The center employs proven methods such as cognitive behavioral therapy and motivational interviewing to deliver personalized care tailored to the unique challenges faced by each client. It emphasizes anger management and the creation of customized treatment plans, providing support for both male and female individuals seeking recovery. The program also features outpatient treatment options including methadone/buprenorphine or naltrexone, ensuring that those in need receive comprehensive assistance for their substance use concerns.

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North Central MO Mental Health Center, located in Brookfield, MO, provides specialized outpatient services for individuals grappling with substance abuse and dual diagnoses. Their approach incorporates evidence-based practices such as cognitive behavioral therapy, motivational interviewing, and anger management, ensuring personalized care for each client. The center distinguishes itself with targeted programs for LGBTQ+ individuals and those facing co-occurring mental health and addiction challenges. Services include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient support. Catering to a diverse clientele encompassing adults, children, adolescents, and both male and female patients, the center fosters a nurturing setting for recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)