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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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North Country Recovery Center

Situated in Whitefield, NH, North Country Recovery Center provides an extensive selection of outpatient treatment options for substance use issues, catering to both adults and children/adolescents dealing with concurrent severe mental health conditions or emotional challenges. The center focuses on various methods including 12-step support, anger management, and short-term interventions, ensuring that care is personalized for each individual. Emphasizing treatments that consider gender-specific needs, North Country Recovery Center offers outpatient programs featuring methadone/buprenorphine or naltrexone, in addition to standard outpatient services. For individuals pursuing professional and tailor-made assistance in a nurturing setting, this center is committed to fostering enduring recovery and overall well-being.

North Louisiana Whole Health Trt Ctr

North Louisiana Whole Health Trt Ctr, located in Shreveport, LA, provides an all-encompassing approach to substance use recovery along with transitional housing options. The center is focused on addressing both substance use issues and severe mental health disorders in adults, as well as emotional challenges in children. They offer a range of treatment options, including intensive outpatient and standard outpatient programs, featuring therapies such as methadone/buprenorphine treatment. The facility emphasizes personalized care by utilizing strategies like anger management, cognitive behavioral therapy, and the Matrix Model. Additionally, they have specialized programs designed for clients with co-occurring conditions and those involved with the justice system. This center serves individuals of all genders, aiming to deliver effective support for sustained recovery and overall wellness.

North Miami Comprehensive Trt Center

The North Miami Comprehensive Treatment Center, located in Miami, FL, provides customized outpatient programs for substance use disorder, designed to meet the unique needs of each client. Emphasizing therapies such as cognitive behavioral therapy, anger management, and brief interventions, the center delivers effective care for adult men and women, including those currently serving in the military. It offers specialized outpatient options, including treatment with methadone, buprenorphine, or naltrexone. Catering to both young adults and adults, the center serves a diverse clientele of both genders. North Miami Comprehensive Treatment Center is committed to aiding individuals in their recovery journey through personalized, evidence-based treatment in a supportive setting.

North Oklahoma County MH Center Inc

North Oklahoma County MH Center Inc. in Oklahoma City, OK, provides outpatient programs for individuals struggling with substance use and those facing the dual challenges of addiction and severe mental health conditions in adults, as well as significant emotional difficulties in children. The center employs therapeutic methods such as anger management, cognitive behavioral therapy, and brief intervention strategies to support a broad range of individuals, including those involved with the criminal justice system, military veterans, and young adults. Catering to adults and seniors of all gender identities, the facility offers standard outpatient care alongside specialized medication-assisted treatment options, including methadone, buprenorphine, or naltrexone. North Oklahoma County MH Center Inc. is dedicated to delivering high-quality, individualized rehabilitation services.

North Palm Beach Recovery Center

North Palm Beach Recovery Center in West Palm Beach, Florida, provides targeted substance abuse care for adults experiencing co-occurring severe mental health conditions, as well as treatment for children with significant emotional difficulties. Their offerings include intensive outpatient, outpatient, and day treatment options, integrating methods such as 12-step facilitation, anger management, and brief intervention. The center also features dedicated programs for active military members, teenagers, and adult men, accommodating a wide range of ages and genders. Renowned for its high standards of care and personalized recovery strategies, this facility creates a nurturing atmosphere for individuals pursuing healing from addiction and mental health concerns.

North Clark Medical Group

North Clark Medical Group in Charlestown, IN, provides extensive outpatient services for addiction and withdrawal management. They have distinct programs for active military members, teenagers, and adult males. Utilizing methods such as 12-step encouragement, short-term counseling, and cognitive behavioral techniques, patients get personalized support for their path to recovery. This location serves adult and elderly individuals of any gender, delivering excellent care through non-residential detox and treatment with methadone, buprenorphine, or naltrexone. North Clark Medical Group is dedicated to assisting people in attaining sustained freedom from addiction and improved health.

North Florida South Georgia

Situated in Valdosta, GA, the North Florida South Georgia rehabilitation center provides outpatient treatment for substance use aimed at adults and young adults. This center focuses on anger management, motivational interviewing, and relapse prevention, making it a suitable choice for those dealing with trauma, co-occurring mental health and substance use issues, as well as veterans. It features personalized programs for both men and women, offering options like outpatient methadone/buprenorphine and naltrexone therapies. The center is dedicated to delivering thorough and supportive care, fostering an environment where individuals can receive compassionate assistance on their journey to overcome addiction and attain sustainable recovery.

North Community Counseling Centers Inc

North Community Counseling Centers Inc. in Columbus, OH, delivers outpatient services for individuals struggling with substance use disorders. They also provide specialized interventions for adults facing concurrent serious mental health conditions. The center's offerings include a range of treatment modalities, such as outpatient programs utilizing methadone, buprenorphine, or naltrexone. Their therapeutic framework integrates techniques like anger management, cognitive behavioral therapy, and motivational incentives. Distinctive programs are available for adult men and women, those impacted by intimate partner violence, and survivors of domestic abuse. Catering to adults, seniors, and young adults across all gender identities, this facility is dedicated to providing high-quality, individualized care to foster lasting recovery.

North Central Mental Health Services

North Central Mental Health Services, located in Columbus, OH, provides outpatient treatment for adults facing substance use issues alongside significant mental health disorders. The center emphasizes 12-step programs, anger management strategies, and short-term interventions, offering personalized outpatient care for those struggling with addiction and emotional struggles. It features distinctive programs aimed at teenagers, individuals with dual diagnoses, and clients involved in the criminal justice system. Catering to both adult men and women of various ages, the center is dedicated to delivering effective treatment through a wide array of specialized services designed to assist individuals in overcoming addiction and mental health difficulties.

North Cottage Program Inc

Situated in Norton, MA, North Cottage Program Inc provides long-term residential treatment for adult males dealing with substance use issues. This center focuses on transitional living arrangements, halfway house services, and sober living options. It emphasizes 12-step methods, anger management techniques, and brief intervention strategies. North Cottage Program Inc is dedicated to serving adult men, including individuals who have faced sexual abuse or trauma. With a strong dedication to high-quality care, this facility supports adults, seniors, and young adults in a nurturing environment conducive to their recovery process.

North Florida South Georgia

North Florida South Georgia, situated in Jacksonville, FL, delivers complete addiction treatment for adults and younger adults. Their offerings include intensive outpatient care, general outpatient services, and outpatient detox. Emphasizing brief intervention, cognitive behavioral therapy, and motivational incentives, the facility supports individuals facing co-occurring mental health and substance use disorders. Specialized tracks are provided for active military personnel, adult men, and adult women. North Florida South Georgia is committed to providing high-quality, effective detoxification and substance use treatment in a nurturing setting for all clients.

North Georgia Recovery Center

North Georgia Recovery Center, situated in Kennesaw, GA, delivers targeted substance abuse rehabilitation services designed for those pursuing sobriety. They offer various treatment modalities, encompassing intensive outpatient, standard outpatient, and day treatment options. Employing methodologies like anger management, brief intervention, and cognitive behavioral therapy, the center prioritizes individualized client support. Distinctive programs are available for active military members, adult males, and adult females. Catering to adult and young adult populations across all genders, this establishment is committed to providing effective, scientifically supported care to aid individuals in achieving lasting recovery.

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North Central Mental Health Services, situated in Columbus, OH, provides outpatient care for individuals of all ages struggling with addiction and related mental health issues. They offer targeted support for teenagers, the LGBTQ+ community, and those facing dual diagnoses. Their approach incorporates 12-step support, strategies for managing anger, and concise therapeutic interventions. Serving both men and women, including older adults, North Central Mental Health Services is dedicated to delivering personalized, effective recovery solutions.

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The North Coast Substance Abuse Council, situated in Eureka, CA, delivers thorough substance use disorder care within a nurturing setting. This establishment features residential options that are long-term, short-term, and available 24/7, all adapted to individual requirements. They offer distinct programs for adult men, adult women, and individuals with trauma histories, ensuring a personalized recovery journey. Employing methods like 12-step facilitation, anger management, and brief intervention, they tackle the specific hurdles faced by each person. The North Coast Substance Abuse Council is committed to providing excellent, scientifically-backed treatment for adults and young adults across all gender identities, aiding them in their recovery process.

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Situated in Canton, NY, North Country Freedom Homes Inc delivers extended residential treatment for adult males battling substance use disorders in a nurturing and secure setting. The center emphasizes 12-step guidance, anger management techniques, and short-term intervention strategies. It focuses particularly on individuals who have faced issues such as intimate partner violence, domestic abuse, and sexual trauma, offering services to both adults and seniors in need of thorough support. This facility also features transitional housing and sober living arrangements, making it a fitting choice for those pursuing a well-structured recovery journey. North Country Freedom Homes Inc is committed to providing high-quality, gender-specific treatment for male clients aiming to conquer addiction and restore their lives.

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Located in Littleton, NH, North Country Recovery Center specializes in outpatient services designed for individuals facing substance use issues. This center provides thorough support for adults dealing with both substance use and significant mental health challenges, in addition to services for children experiencing serious emotional difficulties. The facility offers outpatient options including methadone, buprenorphine, and naltrexone therapies, utilizing a range of methods such as 12-step programs, anger management techniques, and short-term counseling. With a commitment to personalized treatment, the center accommodates clients of all genders and various age brackets. North Country Recovery Center is recognized for its customized care plans and dedication to high-quality treatment solutions.

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Situated in Brooklyn, NY, North Crown Heights provides an extensive array of rehabilitation services. This center focuses on treating substance use disorders, offering transitional housing, and addressing the co-occurrence of substance use and severe mental health conditions in adults, alongside serious emotional challenges in children. Their offerings include intensive outpatient treatment, outpatient care, and partial hospitalization, serving both adults and young adults. North Crown Heights features specialized programs for active military personnel, as well as services tailored for adult men and women. They implement 12-step facilitation, anger management, and brief intervention strategies, making them an essential support system for individuals on the path to recovery.

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North Louisiana Human Services, situated in Natchitoches, LA, provides extensive programs for adults battling addiction alongside significant mental health conditions, and for children with serious emotional challenges. They offer robust intensive outpatient and standard outpatient services, incorporating medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Emphasizing approaches such as 12-step integration, anger management techniques, and cognitive behavioral therapy, the center customizes care plans for each individual. Specialized support is available for teenagers, adult men, and adult women, ensuring services are accessible to all genders and age demographics. North Louisiana Human Services is committed to delivering high-standard care and assistance to individuals on their path to recovery.

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North Philadelphia Health Systems, located in Philadelphia, PA, provides targeted substance use treatment programs designed for adult males. This facility features various options, including long-term, short-term, and round-the-clock residential care for adults, seniors, and young adults. Emphasizing 12-step programs, anger management, and brief intervention techniques, the center delivers thorough support for men pursuing recovery. Its dedication to high-quality care and distinctive programs specifically for adult men positions it as an essential resource for individuals requiring specialized addiction treatment.

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North Philadelphia Health Systems, situated in Philadelphia, PA, delivers extensive programs for detoxification and substance abuse recovery. Their primary focus is on residential care, operating around the clock within a nurturing setting. Employing methods such as 12-step facilitation, anger management, and brief intervention, this establishment crafts treatment strategies specific to each person's needs. Catering to adult and young adult males and females, the center's distinct one-on-one strategy guarantees customized and successful care. North Philadelphia Health Systems is committed to offering top-tier recovery services to support individuals in their path to wellness.

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Situated in Barrow, Alaska, North Slope Borough provides outpatient services for adults facing substance use disorders alongside serious mental health concerns, as well as emotional challenges in children. The center employs proven methods such as 12-step facilitation, anger management, and brief interventions as part of its regular outpatient offerings. Tailored programs are available for adolescents, as well as adult men and women. North Slope Borough caters to both male and female adults and seniors. Committed to delivering high-quality care and personalized treatment, North Slope Borough stands out as a significant support system for those seeking extensive rehabilitation options in the Barrow region.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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