NWVCIL Logo
Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6655 results

North Star Treatment Services

Situated in King of Prussia, PA, North Star Treatment Services specializes in extensive rehabilitation programs for both adults and young adults dealing with substance use issues. Emphasizing personalized care, this center provides various treatment options, including intensive outpatient therapy, standard outpatient programs, and daytime outpatient/partial hospitalization services. By incorporating methodologies such as 12-step support, anger management techniques, and short intervention strategies, the facility guarantees a customized treatment journey for every individual. North Star Treatment Services supports clients of all genders, creating an encouraging and inclusive atmosphere for everyone. If you're in search of effective addiction rehabilitation with a tailored approach, this center is committed to assisting you in achieving enduring recovery.

North Wilkesboro Comp Treatment Center

North Wilkesboro Comp Treatment Center, situated in North Wilkesboro, NC, delivers a full spectrum of addiction recovery care. Their programs include detox and substance use disorder treatment through intensive outpatient, standard outpatient, and outpatient detox options. Employing methods like brief intervention, cognitive behavioral therapy, and contingency management, the center serves adult men and women, including those with trauma histories. They focus on personalized care plans for adults and young adults of all genders, aiming for sustained recovery.

NorthKey Community Care

NorthKey Community Care, located in Owenton, KY, offers an array of specialized rehabilitation services designed for those facing challenges related to substance use and concurrent mental health conditions. The center provides intensive outpatient treatment, standard outpatient programs, and employs various evidence-based methods, such as cognitive behavioral therapy and anger management, to guarantee thorough care for adult clients. Additionally, the facility features distinctive programs aimed at individuals who have undergone intimate partner or domestic violence, addressing their specific circumstances. With an emphasis on adult and senior demographics, NorthKey Community Care is committed to delivering effective, gender-sensitive treatment to foster sustainable recovery and overall well-being.

NorthKey Community Care

Situated in Florence, KY, NorthKey Community Care provides an extensive array of programs for the treatment of substance use disorders and co-occurring mental health issues for both adults and children. The facility offers intensive outpatient therapy, standard outpatient services, and various medication-assisted treatments, including methadone, buprenorphine, and naltrexone. NorthKey Community Care emphasizes methods such as anger management, brief intervention techniques, and cognitive behavioral therapy, catering to adult men and women, as well as individuals who have faced intimate partner or domestic violence. Dedicated to serving adults and seniors of all genders, this center focuses on delivering personalized, high-quality care to assist clients on their journey toward recovery.

NorthKey Community Care

Situated in Covington, KY, NorthKey Community Care provides dedicated rehabilitation services aimed at adults and seniors facing challenges related to substance use and mental health. The center offers a variety of treatment options including intensive outpatient programs, outpatient services, and medications such as methadone/buprenorphine or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, NorthKey serves both men and women, including those affected by domestic violence. The facility designs specific programs and gender-sensitive support to foster a nurturing atmosphere for individuals on their recovery journey. Rely on NorthKey Community Care for thorough and effective rehabilitation solutions.

NorthKey Community Care

Situated in Newport, KY, NorthKey Community Care provides a wide range of treatment options for individuals dealing with substance use disorders, alongside serious mental health challenges. Their services encompass intensive outpatient programs, standard outpatient care, and specialized treatments involving methadone, buprenorphine, or naltrexone. The center employs methods such as anger management and cognitive behavioral therapy to deliver personalized support for both men and women, including those impacted by domestic violence. NorthKey Community Care is dedicated to serving adults and seniors of every gender, emphasizing high-quality care and proven strategies to assist individuals in their recovery journey.

NorthKey Community Care

NorthKey Community Care in Carrollton, KY, delivers dedicated substance use and co-occurring disorder services for individuals of all ages. The center features intensive outpatient and standard outpatient options, incorporating methadone and buprenorphine therapies. Emphasizing anger management, cognitive behavioral techniques, and short-term counseling, programs are customized for each person's unique requirements. Specialized tracks are available for adult men and women, and for survivors of intimate partner violence. NorthKey Community Care provides excellent care to adults and older adults, embracing a kind and all-encompassing rehabilitation philosophy.

NorthLakes Community Clinic

NorthLakes Community Clinic, located in Ashland, WI, delivers outpatient services that concentrate on addressing substance use and co-occurring mental health issues in both adults and children. This center provides customized treatment options, including anger management, cognitive behavioral therapy, and short-term intervention strategies. It features specialized programs for those who have experienced trauma as well as individuals involved in the criminal justice system. Catering to adults and seniors across all gender identities, the clinic provides outpatient methadone/buprenorphine or naltrexone therapies alongside standard outpatient services. With a commitment to high-quality and personalized care, NorthLakes Community Clinic stands out as a reliable choice for individuals in need of comprehensive rehabilitation support.

NorthLakes Community Clinic

Situated in Hayward, WI, NorthLakes Community Clinic stands out as a leading rehabilitation facility, dedicated to addressing substance use issues alongside co-occurring mental health challenges. The center offers a variety of outpatient services, featuring methadone and buprenorphine treatment as well as cognitive behavioral therapy. Distinctive programs specifically designed for adult women and those who have undergone trauma highlight the clinic’s commitment to personalized care. NorthLakes Community Clinic serves adults and seniors across all gender identities, emphasizing an inclusive approach to recovery. With a strong emphasis on anger management and short-term interventions, this center provides exceptional support for individuals on their path to health and recovery.

NorthKey Community Care
Williamstown, KY

NorthKey Community Care, located in Williamstown, KY, provides extensive addiction recovery solutions for individuals of all ages facing dual diagnoses of substance use disorders and mental health issues. Their offerings encompass high-intensity outpatient care, standard outpatient services, and tailored medication-assisted treatment options including methadone and buprenorphine. Employing therapeutic modalities such as anger resolution, early intervention, and cognitive-behavioral techniques, this center serves adult men and women, alongside survivors of relationship violence. Catering to adults and older adults, regardless of gender, NorthKey Community Care delivers effective support and dedicated assistance for those pursuing sobriety and mental wellness.

NorthEastern Center Inc

NorthEastern Center Inc, situated in Albion, IN, stands as a leading provider of outpatient services for adults and seniors battling substance use disorders. This facility excels in addressing complex cases involving co-occurring mental health conditions and addiction. They deliver individualized treatment plans designed to meet unique recovery goals. NorthEastern Center Inc is particularly adept at supporting individuals who have endured intimate partner violence or face dual diagnoses. Their specialized experience extends to assisting those involved in the criminal justice system. The center offers diverse outpatient modalities, including medication-assisted treatment like methadone and buprenorphine, serving both men and women on their path to wellness.

NorthKey Community Care

NorthKey Community Care in Warsaw, KY, delivers thorough treatment for addiction and specialized support for adults with dual diagnoses of substance use and severe mental health conditions, alongside children struggling with emotional disturbances. The facility offers intensive outpatient, outpatient, and standard outpatient services incorporating techniques such as anger management, brief interventions, and cognitive behavioral therapy. Recognizing diverse needs, NorthKey Community Care has developed specific programs for adult men, women, and individuals affected by intimate partner violence, serving adults and seniors regardless of gender. Discover effective care and encouragement at this center focused on complete well-being.

NorthKey Community Care

NorthKey Community Care, located in Falmouth, KY, delivers thorough care for adults facing substance use disorders alongside mental health issues, and for children experiencing significant emotional distress. The facility offers robust outpatient services, including intensive options, and employs medication-assisted treatments like methadone, buprenorphine, and naltrexone. Employing strategies such as anger management, cognitive behavioral therapy, and brief intervention techniques, NorthKey Community Care serves a diverse population including adults of all ages, seniors, and survivors of intimate partner or domestic violence. By providing customized care plans that consider age and gender, NorthKey Community Care is dedicated to delivering exceptional support for individuals pursuing freedom from addiction and mental health concerns.

North West Essex Community

North West Essex Community, situated in Belleville, NJ, provides comprehensive outpatient support for adults and young adults navigating substance use disorders and co-occurring mental health challenges. The center excels in detoxification services, 12-step program integration, and cognitive behavioral therapy. They offer specialized care pathways for individuals with trauma histories, active military members, and veterans. Emphasizing outpatient medically-assisted treatment (MAT) with options like methadone, buprenorphine, or naltrexone, North West Essex Community delivers personalized recovery plans for all genders.

North Sound Center for

The North Sound Center for in Burlington, WA, delivers outpatient substance use disorder services designed for adults, youth, and teenagers. This establishment offers dedicated support for male and female individuals, prioritizing customized recovery strategies. Employing proven therapeutic techniques like motivational interviewing and contingency management, the center guarantees a thorough and successful journey toward sobriety. Their adaptable treatment options, encompassing outpatient methadone, buprenorphine, or naltrexone programs, address a range of requirements. Dedicated to providing excellent care and focusing on personalized interventions, the North Sound Center for is a dependable option for individuals pursuing addiction recovery.

North Texas Addiction Counseling and

Situated in Fort Worth, Texas, North Texas Addiction Counseling provides outpatient services for substance use issues, tailoring its programs for adult men and women, as well as individuals who have faced intimate partner or domestic violence. The center utilizes various therapeutic methods such as anger management, brief intervention, and cognitive behavioral therapy. It also offers outpatient treatment options involving methadone, buprenorphine, or naltrexone for those requiring such support. Catering to adults and young people of all genders, this rehabilitation facility emphasizes high-quality care and evidence-based strategies to assist individuals in their recovery process.

North Texas Addiction Counseling and

Situated in Weatherford, Texas, North Texas Addiction Counseling specializes in both intensive outpatient and outpatient treatment options for individuals struggling with substance use issues and associated mental health disorders, catering to both adults and children. The center offers various targeted therapies, including anger management and cognitive behavioral therapy, along with short-term interventions. It presents customized programs designed specifically for adolescents, as well as adult men and women. This facility is committed to providing a holistic approach to addiction recovery, serving individuals of all genders. Emphasizing personalized care and evidence-based methodologies, North Texas Addiction Counseling is focused on assisting clients in their journey towards rehabilitation.

NorthKey Community Care

NorthKey Community Care in Covington, KY, offers a range of specialized treatment programs for adults and seniors struggling with substance use and co-occurring mental health issues. The center provides intensive outpatient, outpatient, and regular outpatient treatment utilizing evidence-based approaches such as cognitive behavioral therapy and anger management. NorthKey's unique programs cater to adult men and women, as well as individuals who have experienced intimate partner violence or domestic violence. With a focus on quality care and individualized treatment, this facility aims to support clients on their journey to recovery.

Placeholder image

Situated in Boston, MA, North Suffolk Community Services provides extensive treatment for substance use through long-term and 24-hour residential programs. Emphasizing anger management, brief intervention techniques, and cognitive behavioral therapy, this center serves both adult men and women, including those with trauma histories. With a focus on personalized care for adults and young adults of all genders, North Suffolk Community Services develops customized treatment plans to meet unique needs. Renowned for its high-quality support and successful methods, this facility serves as a guiding light for individuals pursuing recovery from substance use disorders in a nurturing and therapeutic setting.

Placeholder image

North Suffolk Community Services, located in Boston, MA, provides a range of evidence-supported treatment options for adults and elderly individuals dealing with substance use disorders and accompanying mental health challenges. The center features intensive outpatient programs, outpatient day treatment, and partial hospitalization services. Employing methodologies such as cognitive behavioral therapy and anger management, this facility serves both men and women, including those who have undergone trauma. With tailored programs for adults and seniors of all genders, North Suffolk Community Services ensures comprehensive support for individuals as they pursue their recovery objectives.

Placeholder image

North Suffolk Community Services, situated in Chelsea, MA, delivers outpatient treatment for individuals of all ages struggling with substance use and concurrent serious mental health challenges. Employing proven therapeutic methods such as cognitive behavioral therapy and motivational interviewing, the center offers targeted support for those navigating anger management and addiction. Its services are specifically designed for adults and seniors experiencing co-occurring mental health and substance use disorders, accommodating all genders. North Suffolk Community Services is distinguished by its thorough programs, customized to meet the distinct requirements of every patient, thereby guaranteeing effective care and assistance on the path to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)