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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, provides a full spectrum of substance use care across multiple modalities such as intensive outpatient, standard outpatient, and medication-assisted treatment (methadone/buprenorphine or naltrexone). Their expertise lies in incorporating 12-step facilitation, anger management techniques, and brief intervention strategies. The center develops personalized treatment plans for young people, adult men, and adult women, catering to both adolescent and adult populations. Serving both male and female individuals, Nystrom and Associates Ltd is committed to delivering high-quality care within a nurturing setting. For those in search of successful addiction treatment that emphasizes customized services and unique program offerings, this organization is devoted to supporting your journey toward wellness.

Oakdale Recovery Center

Oakdale Recovery Center, situated in Canton, MI, offers extensive addiction recovery programs for adults and adolescents. Their services include inpatient detoxification, round-the-clock residential support, and brief residential stays. Oakdale Recovery Center is particularly adept at addressing co-occurring substance use disorders and significant mental health challenges in adults, alongside emotional issues in younger individuals. They utilize proven methods like 12-step facilitation, cognitive behavioral therapy, and contingency management. The center provides tailored programs for individuals with co-occurring disorders, ensuring personalized treatment for both men and women in a nurturing setting designed for impactful recovery.

Oakland Family Services

Situated in Pontiac, MI, Oakland Family Services delivers extensive treatment for substance use in both adults and children. This center is particularly focused on addressing co-occurring substance use and significant mental health issues. It offers various treatment options, including intensive outpatient and standard outpatient programs, ensuring personalized care with methods like cognitive behavioral therapy and anger management. Specialized programs are available for adolescents, women, and individuals facing co-occurring disorders. Catering to clients of all genders, Oakland Family Services is committed to providing exceptional care and assistance for individuals on their path to recovery.

Oakland Psychological Clinic PC

Oakland Psychological Clinic PC, situated in Flint, MI, delivers outpatient treatment for substance use disorders. Their approach centers on personalized care, with specialized services including anger management, cognitive behavioral therapy, and motivational interviewing. Catering to adults and seniors of any gender, the clinic fosters a secure and encouraging atmosphere conducive to recovery. By prioritizing customized treatment strategies, Oakland Psychological Clinic PC guarantees high-quality services designed to meet the distinct requirements of every individual. For those in search of impactful addiction treatment within a supportive environment, this clinic is committed to facilitating your journey toward sustained recovery.

Oakland Psychological Clinic PC

Oakland Psychological Clinic PC in Lake Orion, MI provides outpatient services for individuals struggling with substance use disorders. Their approach emphasizes personalized treatment plans, incorporating techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. This facility caters to adults and seniors of any gender, fostering a supportive atmosphere for addressing individual challenges. A skilled team at Oakland Psychological Clinic PC is dedicated to delivering effective care for those aiming for recovery.

OSF Little Company of Mary Medical Ctr

OSF Little Company of Mary Medical Center in Evergreen Park, IL, provides expert care for adults dealing with substance abuse, co-occurring disorders, and severe mental health challenges, as well as emotional issues in younger patients. The center places an emphasis on intensive outpatient, outpatient, and partial hospitalization options. Employing proven methods like 12-step facilitation, motivational interviewing, and strategies for relapse prevention, this facility serves both men and women. It is dedicated to offering personalized support for adults and youths facing co-occurring conditions. With its focus on quality and specialized services, this center stands out as an essential resource for those in search of comprehensive addiction treatment.

OTRC SUDS
Portland, OR

OTRC SUDS in Portland, OR, delivers complete addiction recovery services for adults and older adults. Clients can choose from intensive outpatient, standard outpatient, and flexible outpatient plans designed for their specific circumstances. This center focuses on effective treatments rooted in scientific research, including cognitive behavioral therapy and the Matrix Model, to ensure excellent support. Dedicated programs are offered for current military members, adult men, and adult women. OTRC SUDS welcomes both male and female individuals, fostering a welcoming and encouraging space for everyone aiming to conquer substance dependency.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Baxter, MN, provides a full spectrum of substance abuse recovery options. Their offerings include intensive outpatient care, general outpatient services, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing strategies such as 12-step facilitation, anger management techniques, and brief intervention, they support adolescents, adult men, and adult women. The facility welcomes both male and female patients of all ages, from children and adolescents to adults. Nystrom and Associates Ltd is dedicated to delivering high-quality, personalized addiction treatment.

Oakland Psychological Clinic PC

Oakland Psychological Clinic PC, situated in Bloomfield Hills, MI, provides outpatient addiction recovery services for adults and seniors. Employing therapeutic modalities like anger management, cognitive behavioral therapy, and motivational interviewing, this center delivers consistent outpatient care with an emphasis on personalized attention. Featuring distinct programs designed for individual needs, both men and women can access the center's thorough offerings. Oakland Psychological Clinic PC is recognized for its dedication to excellent service and customized treatment approaches, positioning it as a leading option for individuals in the region pursuing effective and encouraging substance abuse recovery.

Oakland Family Services

Oakland Family Services located in Berkley, MI, presents an extensive variety of treatment solutions for substance use for both adults and minors, including adolescents who are also facing concurrent mental health challenges. The center features customized programs specifically designed for teens, women, and individuals with dual diagnoses. Treatment options include intensive outpatient, outpatient, and standard outpatient formats. The facility employs proven methods such as anger management, brief intervention, and cognitive behavioral therapy to provide effective care for all clients, regardless of gender. Committed to assisting individuals with substance use issues or significant emotional challenges, this center focuses on facilitating their journey to recovery.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, provides an extensive range of substance use rehabilitation programs designed for adults, teenagers, and children. The center features intensive outpatient care, outpatient services, and specific therapies involving methadone, buprenorphine, or naltrexone. Emphasizing 12-step programs, anger management, and brief interventions, it serves both male and female participants. Tailored programs for adult men, adult women, and adolescents reinforce a personalized approach to treatment. Nystrom and Associates Ltd takes pride in offering high-quality, gender-sensitive rehabilitation to assist individuals on their journey toward recovery.

Oak Integrated Care
Mount Holly, NJ

Oak Integrated Care, situated in Mount Holly, NJ, delivers extensive addiction recovery support and expert services for adults managing concurrent serious mental health conditions. The center features outpatient options such as opioid agonist therapy (methadone/buprenorphine) or opioid antagonist treatment (naltrexone), along with cognitive behavioral therapy, anger management strategies, and brief intervention techniques. Tailored programs are available for active military members, adult men, and adult women, reflecting Oak Integrated Care's commitment to serving a wide range of individuals. This establishment is dedicated to providing high-quality, personalized care plans for adults and young adults of all genders, aiding them in their path toward lasting recovery.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Duluth, MN, delivers tailored recovery services for individuals across all age groups, including adults, teenagers, and younger persons. They provide comprehensive treatment tiers such as intensive outpatient services, general outpatient care, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing methodologies like 12-step encouragement, emotional regulation training, and brief counseling, the facility addresses the distinct requirements of adult males, adult females, and adolescents. Nystrom and Associates Ltd is committed to delivering effective support for those pursuing freedom from addiction. Their gender-affirming programs foster a secure and understanding atmosphere for both male and female participants as they work toward lasting abstinence.

Oakland Psychological Clinic PC

Oakland Psychological Clinic PC, situated in Fraser, MI, provides focused substance use recovery through its outpatient and regular outpatient services. Employing methods like anger management, cognitive behavioral therapy, and motivational interviewing, this establishment delivers personalized support for adults and seniors, irrespective of gender. What distinguishes Oakland Psychological Clinic PC is its customized care strategies designed for each individual's specific requirements. Prioritizing high-quality treatment and scientifically validated approaches, it stands as a reliable choice for those pursuing effective and individualized addiction recovery.

ORTC LLC
Pendleton, OR

ORTC LLC, located in Pendleton, OR, provides a full range of treatment options for substance use, including outpatient services, as well as methadone/buprenorphine and naltrexone programs. The center emphasizes customized care by utilizing various strategies such as 12-step facilitation, anger management, and brief intervention techniques. Catering to a wide array of demographics, ORTC LLC features specialized programs for adult men, adult women, and veterans. The facility is dedicated to serving both adults and young adults across all gender identities, ensuring a personalized approach to treatment. Clients can anticipate high-quality care aimed at fostering their recovery and overall well-being. For anyone in need of a nurturing space to confront substance use issues, this center delivers effective programs focused on individualized support.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Hutchinson, MN, provides comprehensive outpatient treatment for substance use disorders. Their services include intensive outpatient programs, general outpatient care, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center utilizes therapeutic approaches such as 12-step facilitation, anger management, and brief interventions. Nystrom and Associates Ltd supports adolescents, adult men, and adult women, offering gender-specific programming for both male and female clients, as well as care for children and adolescents. They are dedicated to delivering personalized and effective care to aid individuals in achieving and maintaining sobriety.

Oakland Psychological Clinic PC

Oakland Psychological Clinic PC, situated in Livonia, Michigan, delivers targeted substance abuse rehabilitation via its outpatient programs. Employing therapeutic strategies like anger management, cognitive behavioral therapy, and motivational interviewing, this establishment ensures holistic support customized for each person's unique requirements. Emphasizing a personalized care model, the clinic caters to adults and elderly individuals across all genders. Oakland Psychological Clinic PC distinguishes itself through its dedication to high-quality service and its unwavering mission to assist patients in conquering addiction. For those in search of impactful outpatient treatment characterized by a personal approach, this clinic is committed to fostering your path toward healing.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Moorhead, MN, delivers targeted substance abuse recovery programs for both young people and adults. Their offerings include comprehensive outpatient services, intensive outpatient care, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center employs evidence-based strategies such as 12-step integration, anger management training, and brief intervention techniques, ensuring a personalized approach to each client's recovery path. Dedicated programs are provided for adolescents, adult men, and adult women. At Nystrom and Associates Ltd, individuals of all ages and genders receive dedicated support and effective treatment to aid their return to wellness.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Mankato, MN, provides extensive support for individuals struggling with substance misuse. They offer various levels of care, including intensive outpatient, outpatient, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center is particularly skilled in utilizing approaches such as 12-step facilitation, anger management techniques, and brief intervention strategies. Nystrom and Associates Ltd designs personalized treatment for adolescents, adult men, and adult women, accommodating a wide range of ages and genders. Their services extend to care for children and adolescents, ensuring that each person receives a treatment plan developed specifically for their needs. This dedication to high-quality care and specialized programming establishes Nystrom and Associates Ltd as a leading provider of effective and compassionate addiction recovery services.

Oaklawn Psychiatric Center Inc

Oaklawn Psychiatric Center Inc, located in Goshen, IN, provides targeted outpatient support for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. Emphasizing strategies such as 12-step facilitation, anger management, and short-term interventions, this center customizes its approach to fit the unique requirements of each client. Specialized programs are available for adolescents, adult males, and individuals with dual diagnoses. The range of services includes outpatient options for methadone, buprenorphine, or naltrexone therapy, alongside standard outpatient counseling. Oaklawn Psychiatric Center Inc is committed to delivering high-quality rehabilitation care for both men and women in need.

Oakland Family Services

Situated in Walled Lake, MI, Oakland Family Services delivers a wide range of substance use recovery services for both adults and youth dealing with simultaneous mental health challenges. The facility offers intensive outpatient, outpatient, and standard outpatient treatment options, incorporating methods like anger management, brief intervention, and cognitive behavioral therapy. It features tailored programs for teens, women, and clients managing dual diagnoses, addressing a broad spectrum of requirements. Catering to clients of all genders, Oakland Family Services emphasizes providing exceptional care to facilitate individuals' journeys toward healing and recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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