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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Nsight Mental Health and Wellness

Nsight Mental Health and Wellness, situated in Newport Beach, California, offers tailored rehabilitation services focusing on substance use recovery, transitional housing, and the treatment of co-occurring substance use disorders along with significant mental health issues in adults, as well as serious emotional challenges faced by children. The facility provides a range of treatment options including intensive outpatient programs, outpatient day services, and partial hospitalization, utilizing methodologies like 12-step support, anger management techniques, and brief intervention strategies. Furthermore, it features specialized programs designed for active duty military personnel, adult males, and adult females, addressing the needs of adults and young adults of every gender. The center prioritizes high-quality, individualized care that meets the unique requirements of each client.

Nuview Treatment Center

Situated in Los Angeles, CA, Nuview Treatment Center is dedicated to providing focused treatment for adults and young adults facing substance use disorders alongside co-occurring mental health challenges. The center offers a range of services including intensive outpatient therapy, day treatment programs, and partial hospitalization. Their treatment methods incorporate anger management techniques, brief interventions, and cognitive behavioral strategies. Nuview Treatment Center serves both men and women, including those who have been affected by intimate partner or domestic violence. With an emphasis on personalized care and effective programs, this facility is committed to assisting individuals in attaining sustained recovery and enhanced mental health.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Big Lake, MN, delivers extensive treatment options for substance use disorders for both adults and teenagers. The facility offers a variety of services including intensive outpatient programs, general outpatient care, and methadone/buprenorphine or naltrexone treatments. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, the center serves adult men, adult women, and youths. Nystrom and Associates Ltd is known for its gender-specific approaches, providing individualized care plans for male and female clients. With its commitment to high-quality service and specialized programs, this center stands out as a significant support for those in need of effective and customized addiction treatment.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Big Lake, MN, provides an extensive variety of treatment options for individuals dealing with substance abuse and concomitant mental health disorders, catering to both adults and children. The center offers flexible choices, including long-term, short-term, and 24-hour residential care, designed to meet the unique requirements of each client. Employing methodologies such as 12-step support, anger management techniques, and brief intervention strategies, Nystrom and Associates Ltd formulates customized treatment plans. With a strong emphasis on personalizing care, the center ensures that each individual receives focused attention and support throughout their recovery journey. The center welcomes both males and females, creating an encouraging atmosphere for healing.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Saint Paul, MN, specializes in providing comprehensive treatment for substance use disorders among both adults and teenagers. The center features various treatment modalities, including intensive outpatient programs, outpatient services, and options for methadone, buprenorphine, or naltrexone. Emphasizing 12-step approaches, anger management, and brief interventions, the facility designs its programs to address the unique needs of adult men, adult women, and adolescents. Nystrom and Associates Ltd is committed to offering exceptional care for those pursuing effective addiction recovery in a nurturing setting.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Elk River, MN, specializes in a wide array of substance use rehabilitation programs designed to meet diverse individual needs. The center offers intensive outpatient services, general outpatient care, and medications such as methadone/buprenorphine or naltrexone for treatment. Emphasizing techniques like 12-step facilitation, anger management, and brief interventions, it serves a broad client base that includes adolescents, adult men, and adult women. Nystrom and Associates Ltd is committed to providing inclusive support for adults and minors of any gender, ensuring high-quality care delivered by skilled professionals dedicated to helping clients achieve sustainable recovery.

Nystrom and Associates Ltd

Nystrom and Associates Ltd located in Cambridge, MN, provides extensive treatment options for substance use, including intensive outpatient, outpatient, and programs utilizing methadone, buprenorphine, or naltrexone. The facility implements strategies such as 12-step facilitation, anger management, and brief intervention tailored for adult men and women, adolescents, and those impacted by intimate partner violence. With programs designed for different genders and age ranges, Nystrom and Associates Ltd focuses on personalized treatment to address varied challenges. Patients can anticipate high-quality, evidence-based care offered by a team of skilled professionals, making it a prominent option for individuals seeking compassionate and effective support in their recovery journey.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Rochester, MN, provides a wide range of treatment options for substance use disorders for both adults and teenagers. The center features intensive outpatient programs, standard outpatient services, as well as specific outpatient treatments with methadone/buprenorphine or naltrexone. Emphasizing methods like 12-step support, anger management, and brief interventions, this facility serves adult men and women, along with adolescents. Nystrom and Associates Ltd develops customized treatment plans for every client, ensuring effective support for both genders. If you're looking for a nurturing setting for addiction recovery, this center is committed to guiding you toward sustained sobriety.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Eden Prairie, MN, delivers extensive addiction treatment services aimed at both adults and teenagers. This facility offers various programs, including intensive outpatient therapy, standard outpatient care, and targeted treatments with methadone/buprenorphine or naltrexone. Emphasizing techniques like 12-step support, anger management, and brief interventions, the center addresses the unique needs of adult men, adult women, and adolescents. Gender-specific programs ensure personalized approaches to care. Nystrom and Associates Ltd stands out for its commitment to providing high-quality addiction rehabilitation, making it a preferred option for those in search of effective and empathetic treatment in the Eden Prairie region.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Minneapolis, MN, provides a wide range of substance use treatment options along with tailored support for individuals facing both substance use issues and significant mental health challenges or emotional struggles. The facility features intensive outpatient programs, standard outpatient services, and specialized treatments using methadone, buprenorphine, or naltrexone. Emphasizing approaches such as 12-step support, brief intervention techniques, and cognitive behavioral therapy, this center serves adult males and females, including those who have suffered from intimate partner or domestic violence. Catering to both adults and children/adolescents, it also offers gender-specific programs. Patients can look forward to receiving exceptional, personalized treatment at this esteemed rehabilitation facility.

Nystrom and Associates Ltd

Situated in Hopkins, MN, Nystrom and Associates Ltd provides focused treatment for substance abuse among adults facing significant mental health challenges, alongside services for children dealing with severe emotional issues. The center features both intensive outpatient and outpatient programs, offering treatments like methadone/buprenorphine or naltrexone. With approaches including 12-step programs, anger management, and short interventions, the facility serves adult men and women, including those affected by intimate partner violence. Catering to both adult and child/adolescent clients, and offering gender-specific programs, Nystrom and Associates Ltd delivers holistic support in a nurturing setting.

Nystrom and Associates Ltd

Situated in Osseo, MN, Nystrom and Associates Ltd delivers a wide range of treatment programs for substance use tailored to both adults and teenagers. The center features intensive outpatient programs, general outpatient services, as well as options for outpatient treatment using methadone/buprenorphine or naltrexone. Emphasizing 12-step methods, anger management techniques, and brief intervention strategies, this facility serves clients of all genders. Additionally, there are specialized programs designed for adolescents, adult males, and adult females. Known for its commitment to high-quality care and personalized treatment strategies, Nystrom and Associates Ltd is devoted to assisting individuals on their recovery journey.

Nystrom and Associates Ltd

Nystrom and Associates Ltd located in Stillwater, MN, provides extensive treatment for substance use by offering options like intensive outpatient, outpatient, and medications such as methadone, buprenorphine, or naltrexone. Their methods are grounded in evidence, including 12-step programs, brief interventions, and cognitive behavioral therapy, accommodating adults as well as children and adolescents of all genders. The center has specialized programs aimed at adult men, women, and those who have faced intimate partner or domestic violence. With a commitment to high-quality care and tailored treatment, this facility fosters a nurturing atmosphere for individuals on their journey to recovery from addiction.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, situated in Minneapolis, MN, delivers a wide range of substance use recovery programs designed for both adults and teenagers. The facility features intensive outpatient care, various outpatient offerings, and treatment options involving methadone/buprenorphine or naltrexone. Emphasizing 12-step methods, anger management techniques, and brief interventions, the center serves adult men, adult women, and adolescents. Its targeted programs for distinct age groups and genders guarantee personalized support for each person. Nystrom and Associates Ltd is committed to providing effective, research-supported treatment to aid individuals in their recovery process.

Nystrom and Assicuates Ltd

Nystrom and Associates Ltd, situated in Minneapolis, MN, delivers a wide range of treatment options for substance use disorders affecting both adults and teenagers. The center features programs such as intensive outpatient treatment, outpatient services, as well as medication-assisted treatments including methadone, buprenorphine, and naltrexone. With expertise in 12-step facilitation, anger management, and brief intervention methods, the facility serves adult males, adult females, and adolescents alike. Nystrom and Associates Ltd emphasizes personalized care, ensuring that both men and women receive quality support as they tackle addiction. The center is committed to helping individuals navigate their recovery journey through customized programs that address their unique needs.

Nystrom and Associates Ltd

Nystrom and Associates Ltd located in Alexandria, MN, provides a wide range of treatment options for those struggling with substance use. The facility features intensive outpatient services, standard outpatient programs, and specialized treatments with methadone/buprenorphine or naltrexone. Emphasizing a 12-step recovery model, anger management strategies, and brief intervention techniques, the center serves adolescents, adult males, and adult females. Catering to both adults and younger populations, it ensures tailored care for male and female clients alike. Nystrom and Associates Ltd in Alexandria is dedicated to offering personalized, high-quality support to help individuals navigate their recovery journey from addiction.

Nystrom and Associates Ltd

Nystrom and Associates Ltd, located in Fergus Falls, MN, provides individualized programs for substance use recovery. The center specializes in intensive outpatient services, standard outpatient support, and treatments utilizing methadone, buprenorphine, or naltrexone. Emphasizing 12-step principles, anger management, and concise intervention methods, the facility addresses the needs of adolescents as well as adult men and women. Catering to both adults and younger clients, it ensures that services are tailored to meet the specific needs of each gender. Nystrom and Associates Ltd is recognized for its diverse approach to treatment and a strong dedication to helping individuals on their journey to overcoming substance use challenges.

Nystrom and Associates Ltd

Situated in Bemidji, MN, Nystrom and Associates Ltd specializes in a wide range of substance abuse treatment options for both adults and teenagers. The facility features intensive outpatient programs, standard outpatient services, as well as outpatient treatment using methadone, buprenorphine, or naltrexone. With an emphasis on 12-step support, anger management, and brief intervention strategies, Nystrom and Associates Ltd customizes its treatment plans to address the unique requirements of each client. The center offers specific programs aimed at adolescents, adult men, and adult women. Nystrom and Associates Ltd fosters an inclusive and supportive atmosphere for all clients, regardless of gender. Discover exceptional care and individualized treatment at this esteemed rehabilitation facility.

Novant Health Forsyth Medical Center

Novant Health Forsyth Medical Center, located in Winston Salem, NC, provides extensive support for adults and young adults struggling with addiction and co-occurring severe mental health disorders. Their services encompass intensive outpatient, outpatient day treatment, and partial hospitalization options, incorporating methodologies like 12-step facilitation, anger management, and cognitive behavioral therapy. Dedicated to personalized attention, the center offers distinct treatment paths for male and female patients. The facility's dedication to high-quality, customized programs positions it as a leading provider for individuals pursuing impactful and individualized recovery solutions.

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Lancaster, PA

Situated in Lancaster, PA, "Nuestra Clinica" delivers extensive substance abuse treatment for both adults and young adults dealing with concurrent severe mental health challenges. This center features intensive outpatient and outpatient programs, offering treatment alternatives such as methadone/buprenorphine and naltrexone. Emphasizing 12-step support, anger management, and brief intervention strategies, the facility serves adult men and women, including those with a history of sexual trauma. "Nuestra Clinica" is dedicated to providing personalized care for every individual, prioritizing effective treatment for all patients in their recovery journey.

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Lancaster, PA

Nuestra Clinica, located in Lancaster, PA, provides dedicated substance use treatment specifically designed for adult males within a nurturing and secure setting. The center offers a range of treatment options, including long-term residential care, 24-hour residential programs, and short-term stays. The therapeutic methods employed here incorporate 12-step principles, cognitive behavioral therapy, and anger management strategies. Nuestra Clinica also includes specialized programs for adult men, individuals who have faced sexual abuse, and those who have experienced trauma. Focusing on adults, including seniors and young adults, this center is committed to delivering personalized care to its male clients, assuring effective treatment and support throughout their recovery process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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