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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Ohlhoff Recovery Programs
San Francisco, CA

Ohlhoff Recovery Programs in San Francisco, CA, specializes in extended residential care for adult and senior men struggling with substance use disorders. They provide a continuum of care including transitional housing, halfway house services, and sober living environments, all under constant supervision and assistance. Their therapeutic methods are grounded in proven strategies such as 12-step program integration, brief intervention techniques, and cognitive behavioral therapy, designed for effective addiction treatment. Every resident receives a personalized care plan at Ohlhoff Recovery Programs, acknowledging that each person's journey to recovery is distinct. For those in search of thorough and effective addiction treatment in a nurturing setting, Ohlhoff Recovery Programs is committed to supporting individuals on their path to sustained wellness.

Ohlhoff Recovery Programs
San Francisco, CA

Ohlhoff Recovery Programs, situated in San Francisco, CA, delivers a complete suite of support for those pursuing freedom from addiction. The center provides inpatient detox, round-the-clock residential support, and shorter residential stays. Emphasizing 12-step principles, emotional regulation techniques, and concise counseling, Ohlhoff assists adult men and women, including those in the armed forces. Focusing on both adults and young adults, this establishment features transitional living options like halfway houses and sober living residences. Ohlhoff Recovery Programs is committed to offering excellent treatment and guidance for individuals on their path to lasting recovery.

Olive Branch Recovery

Olive Branch Recovery, situated in Denton, TX, delivers comprehensive outpatient treatment for adults and young adults struggling with substance use disorders. Their approach is highly individualized, emphasizing relapse prevention and tailored counseling strategies. The center caters to both male and female patients, and convenient telemedicine options are available. Services include outpatient treatment with methadone, buprenorphine, or naltrexone. Olive Branch Recovery is dedicated to providing effective, holistic care for individuals embarking on their recovery journey.

Olive Branch Recovery
Springdale, AR

Olive Branch Recovery, situated in Springdale, AR, extends outpatient detox and substance use treatment to adults and young adults. Their specialized services emphasize 12-step integration, preventing relapse, and addiction counseling. Adhering to a personalized care model, Olive Branch Recovery serves both male and female patients needing effective addiction recovery. From detox to outpatient methadone, buprenorphine, or naltrexone services, this establishment guarantees a thorough and tailored path to recovery for everyone.

Olympic Behavioral Health LLC

Olympic Behavioral Health LLC, located in Lake Worth, FL, provides an extensive range of addiction recovery services along with supportive housing alternatives. This center focuses on addressing both substance use issues and significant mental health disorders in adults, as well as emotional challenges faced by children. The treatment options include intensive outpatient programs, outpatient services, and partial hospitalization, all utilizing proven methodologies such as 12-step programs, anger management strategies, and brief counseling sessions. Additionally, Olympic Behavioral Health LLC features targeted programs for individuals who have faced challenges such as intimate partner violence, sexual trauma, or other forms of trauma. Committed to delivering exceptional care, the center caters to clients of diverse genders and age ranges, ensuring personalized treatment plans.

Olympus Recovery LLC.
Delray Beach, FL

Olympus Recovery LLC. located in Delray Beach, FL, specializes in extensive substance use rehabilitation for both adults and young adults facing significant mental health challenges. The facility offers various treatment options, including intensive outpatient services, outpatient day programs, and partial hospitalization. Utilizing methods like 12-step facilitation, anger management techniques, and brief interventions, the center addresses a wide array of needs. Olympus Recovery LLC. also features dedicated programs for active military personnel, as well as specific services for adult men and women, ensuring that care is appropriately customized. With a commitment to gender-specific treatment, this center provides personalized support, making it a reputable choice for those seeking effective recovery solutions.

On Demand Counseling
Youngstown, OH

On Demand Counseling in Youngstown, OH, delivers thorough substance abuse treatment and support for those facing co-occurring mental health challenges. The center features intensive outpatient programs, general outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Their approach emphasizes 12-step facilitation, anger control techniques, and brief intervention strategies. Serving adult men and women, including those with a history of trauma, and young adults, On Demand Counseling is committed to offering effective care and assistance for lasting recovery and well-being.

Old Vineyard Behavioral Health Service

Old Vineyard Behavioral Health Service in Winston-Salem, NC, delivers a full spectrum of addiction recovery options. Their services encompass inpatient hospital detoxification and treatment, with tailored programs for active military, young people, and adult men. Emphasizing anger management, cognitive behavioral techniques, and strategies to prevent recurrence, the center serves individuals and families across age groups and genders. They are committed to personalized care, providing excellent support for those pursuing freedom from addiction.

On Demand Counseling
East Liverpool, OH

On Demand Counseling, situated in East Liverpool, OH, provides focused treatment for adults grappling with substance use and co-occurring serious mental health challenges, along with support for children experiencing emotional difficulties. This center offers both intensive outpatient and outpatient programs, featuring treatments such as methadone/buprenorphine or naltrexone. Emphasizing 12-step support, anger management techniques, and concise intervention strategies, the facility serves both men and women, including individuals who have faced trauma. Catering to adults and young adults from all backgrounds, On Demand Counseling ensures personalized care that meets the unique needs of each client, making it a key support system for those in need of effective rehabilitation options.

OhioGuidestone
Findlay, OH

OhioGuidestone, located in Findlay, OH, provides targeted treatment for substance use disorders in both adults and children facing significant mental health challenges. Their programs include intensive outpatient, outpatient, and day treatment options that utilize research-backed methodologies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. Special attention is given to the needs of pregnant and postpartum women, along with personalized support for adult and senior clients of all genders. The center's dedication to high-quality care and customized rehabilitation programs positions OhioGuidestone as a reliable option for individuals looking for thorough rehabilitation solutions in the Findlay region.

OnCall Healthy Living Program

Situated in Northampton, MA, the OnCall Healthy Living Program provides outpatient detox services, treatment for substance use disorders, and options for methadone/buprenorphine or naltrexone therapy. This center excels in brief interventions, cognitive behavioral therapy, and contingency management/motivational incentives. With a special emphasis on supporting pregnant and postpartum women, the program serves adults and young adults of diverse genders. The facility is committed to delivering high-quality care in a nurturing setting, offering tailored treatment plans to support individuals in their recovery process. If you or someone you care about is looking for addiction treatment, the OnCall Healthy Living Program is dedicated to guiding you toward sustainable sobriety.

OhioGuidestone
Toledo, OH

OhioGuidestone in Toledo, OH, delivers thorough care for addiction and dual diagnoses involving mental health issues in adults, alongside significant emotional challenges in young people. Their treatment plans, including intensive outpatient, outpatient services, and day treatment, are personalized using proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy. OhioGuidestone supports adult men and women, and older adults, with gender-specific assistance. The center is committed to providing excellent treatment to foster enduring recovery and enhance mental well-being.

Oklahoma Treatment Services LLC

Oklahoma Treatment Services LLC, located in McAlester, OK, provides specialized outpatient care for adults dealing with substance use disorders and co-occurring mental health challenges, as well as support for children experiencing emotional disturbances. Their expertise lies in relapse prevention and substance use disorder counseling, offering medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center features distinct programs designed for active duty military personnel, adult men, and women. Catering to a diverse clientele of adults and young adults, regardless of gender, Oklahoma Treatment Services LLC is committed to delivering personalized, evidence-based interventions to foster sustained recovery and overall well-being.

Olalla Recovery Centers

Olalla Recovery Centers, located in Olalla, WA, provides a wide range of services for individuals battling addiction, including detoxification and comprehensive substance use treatment. The center features various options, such as long-term residential care, residential detox, and around-the-clock residential programs designed for both adults and young adults. With its focus on individualized support, Olalla Recovery Centers employs methods like 12-step facilitation, anger management, and brief intervention strategies. Tailored programs specifically address the unique needs of both men and women, ensuring that services are accessible to all clients. Renowned for its high-quality care and nurturing atmosphere, Olalla Recovery Centers stands out as an excellent option for those in need of customized addiction recovery solutions.

Okanogan Behavioral Healthcare

Okanogan Behavioral Healthcare, located in Omak, WA, delivers an extensive array of services tailored to tackle substance use challenges and concurrent mental health conditions. The center features both intensive outpatient and standard outpatient treatment options, offering therapies such as methadone/buprenorphine and naltrexone management. Emphasizing evidence-based approaches like 12-step guidance, brief interventions, and cognitive behavioral therapy, the facility customizes its programs to meet individual needs, ensuring that clients receive focused support. Catering to both adults and younger populations, the center welcomes clients of all genders. Okanogan Behavioral Healthcare is particularly notable for providing transitional housing and halfway house facilities, serving as an essential support system for individuals on their recovery journey.

Oklahoma Treatment Services

Oklahoma Treatment Services in Ponca City, Oklahoma, delivers targeted outpatient addiction recovery programs for adults and young adults. This center offers diverse treatment modalities such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient care, and concise intervention sessions. Employing cognitive behavioral therapy and motivational interviewing, the center prioritizes personalized client support. Special services are available for active military members, adult males, and adult females. Oklahoma Treatment Services is dedicated to providing high-quality, inclusive addiction treatment for all individuals.

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OhioGuidestone, located in Bryan, OH, provides an extensive array of rehabilitation services. This center is dedicated to treating substance use issues for both adults and children who may also be facing mental health challenges. The treatment options available include intensive outpatient programs, outpatient care, and daytime treatment sessions. Emphasizing methods such as 12-step facilitation, cognitive behavioral therapy, and brief therapeutic interventions, OhioGuidestone customizes its approaches based on the specific needs of each individual. The facility caters to adults and seniors of diverse backgrounds, distinguishing itself by prioritizing personalized care, thus ensuring a high standard of tailored treatment for those seeking to overcome substance use disorders and mental health issues.

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Napoleon, OH

OhioGuidestone located in Napoleon, OH, specializes in various treatment options, addressing both substance use disorders and co-occurring serious mental health issues in adults, as well as significant emotional challenges in children. The center offers a spectrum of services, including intensive outpatient care, long-term residential treatment, and outpatient options. Using methodologies like 12-step support, brief interventions, and cognitive behavioral therapy, OhioGuidestone customizes its offerings to fit personal circumstances. This facility emphasizes a personalized approach, catering to adults and seniors across all genders. Known for delivering exceptional care in both addiction recovery and mental health assistance, OhioGuidestone is recognized for its thorough and individualized treatment programs.

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OhioGuidestone, located in Dover, OH, provides extensive care for individuals struggling with substance abuse. Their offerings include extended stays in residential settings, round-the-clock residential support, and shorter residential programs. They are adept at utilizing methods such as 12-step program integration, anger regulation techniques, and concise intervention strategies. Notably, they offer specialized services tailored to adult women and individuals facing concurrent mental health and addiction challenges. OhioGuidestone assists adults, older adults, and younger adults, with a particular emphasis on supporting women. This establishment is dedicated to delivering high-quality, research-backed treatment within a nurturing and organized setting for those pursuing freedom from addiction.

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Defiance, OH

OhioGuidestone, located in Defiance, OH, provides targeted care for individuals of all ages facing addiction and concurrent mental health challenges. Their specialized services include intensive outpatient and daily outpatient programs, employing proven therapeutic methods like 12-step integration and cognitive behavioral techniques. OhioGuidestone is distinguished by its commitment to creating unique treatment paths for every individual. Catering to adults and seniors regardless of gender, the center fosters a nurturing atmosphere conducive to recovery. For those desiring excellent care and custom-made recovery strategies, OhioGuidestone offers a complete and caring resource for their path to wellness.

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Situated in Polk, PA, Oil Region Recovery delivers extensive addiction treatment services for both adults and young adults. The center focuses on detoxification, addressing substance use disorders, and managing coexisting mental health conditions. With options for long-term residential care, residential detox programs, and round-the-clock residential support, patients can benefit from personalized treatment plans. Oil Region Recovery incorporates methods such as 12-step facilitation, anger management, and brief interventions. Additionally, the facility offers tailored programs for active duty service members, as well as distinct services for adult men and women. Catering to a diverse clientele, Oil Region Recovery is dedicated to providing effective care and assistance to those on their journey to recovery from addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)