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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Outpatient Center

The Athens, GA Outpatient Center delivers thorough addiction treatment for adults and adolescents. Their expertise encompasses detoxification, substance use disorder therapy, and dual diagnosis care. They offer intensive outpatient, day treatment, and partial hospitalization programs. Services include 12-step support, anger management techniques, and cognitive behavioral therapy. The center welcomes male and female patients, including survivors of intimate partner violence. Personalized treatment plans are available for adult men and women. The Outpatient Center in Athens, GA is dedicated to high-quality support for those pursuing recovery from addiction and mental health issues.

Outreach Community Health Center Inc

Outreach Community Health Center Inc. in Milwaukee, WI, provides extensive substance use treatment for both adults and young individuals experiencing dual diagnoses. Their services encompass intensive outpatient programs, standard outpatient services, and medication-assisted treatment options including methadone, buprenorphine, and naltrexone. The center employs proven therapeutic methods, such as brief intervention, cognitive behavioral therapy, and the Matrix Model, to ensure customized support for each client. They have particular expertise in addressing co-occurring disorders, serving a diverse clientele of adults and older adults. Outreach Community Health Center Inc. is committed to delivering high-quality, individualized care aimed at fostering lasting recovery.

Outreach Development Corporation

Situated in Brentwood, NY, the Outreach Development Corporation delivers extensive treatment options for substance use for both adults and young adults. The facility offers outpatient services including methadone, buprenorphine, and naltrexone treatments, along with standard outpatient care and specific programs designed for active military members as well as adult males and females. Emphasizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, the center customizes its approach to cater to the unique needs of its clients. Committed to excellence, the Outreach Development Corporation aims to support individuals—both men and women—on their path to recovery.

Outreach Development Corporation RR

Situated in Brentwood, NY, Outreach Development Corporation RR specializes in treating substance use disorders among adult men, seniors, and young adults. This facility focuses on providing thorough support for individuals grappling with both substance use and significant mental health challenges, as well as addressing serious emotional issues in children. Offering a variety of programs, including long-term, short-term, and around-the-clock residential care, the center employs proven methods such as 12-step strategies, anger management sessions, and cognitive behavioral therapy. Distinctive programs are available for those who have endured sexual abuse or trauma. Outreach Development Corporation RR is dedicated to delivering high-quality treatment to male clients in a nurturing setting.

Overcome Wellness and Recovery LLC

Overcome Wellness and Recovery LLC, located in Lakewood, NJ, provides extensive care for addiction and coinciding mental health conditions. Adults and young adults can access intensive outpatient, outpatient, and day treatment services here. Utilizing strategies like brief intervention, cognitive behavioral therapy, and motivational interviewing, the center customizes recovery paths for each person. Dedicated programs exist for adult men, adult women, and individuals dealing with dual diagnoses. Overcome Wellness and Recovery LLC is committed to delivering high-quality support, guiding everyone toward a healthier, more fulfilling life.

Our Hope Association
Grand Rapids, MI

Situated in Grand Rapids, MI, Our Hope Association provides targeted rehabilitation services for adult women facing challenges related to substance use and concurrent significant emotional difficulties. The center offers a range of programs, including long-term and 24-hour residential options, as well as short-term stays. These programs implement various methods, such as 12-step support, anger management techniques, and brief interventions. Specialized services are available for those who have undergone intimate partner violence, domestic abuse, and sexual trauma. This women-only facility aims to deliver exceptional care within a nurturing atmosphere, ensuring that the unique needs of each client are met effectively.

Our Hope Association
Grand Rapids, MI

Nestled in Grand Rapids, MI, Our Hope Association provides tailored rehabilitation programs for adult women facing challenges with substance abuse alongside significant mental health disorders. The center features long-term residential options, outpatient services, and standard outpatient treatment, incorporating methods such as 12-step facilitation, anger management, and brief intervention strategies. This facility serves a diverse demographic, including adults, seniors, and young adults who have been impacted by intimate partner violence, domestic violence, or sexual trauma. With a commitment to supporting women, Our Hope Association delivers comprehensive care and assistance for those on their journey to recovery and wellness.

Outreach and Crisis Counseling Servs

Outreach and Crisis Counseling Servs in Columbus, OH, delivers complete addiction recovery programs for adults and adolescents. This establishment provides hospital-based inpatient detox and treatment for drug and alcohol dependence, addressing concurrent mental health conditions. Featuring dedicated tracks for adult males, adult females, and individuals with dual diagnoses, the center delivers personalized support adapted to each client's specific requirements. Employing methods like 12-step encouragement, emotional regulation techniques, and concise counseling strategies, the facility guarantees a well-rounded and successful rehabilitation journey. Individuals can anticipate superior treatment within a nurturing atmosphere designed to foster sustained sobriety.

Outpatient Addiction Recovery Services

Outpatient Addiction Recovery Services in Aliquippa, PA, provides an extensive range of substance use treatment options through its outpatient programs, which include methadone, buprenorphine, and naltrexone therapies. This center adopts a personalized approach to treatment, ensuring that it meets the unique needs of both adults and young adults across all gender identities. Emphasizing high-quality care and individualized attention, the facility creates a nurturing atmosphere for those committed to overcoming addiction. The comprehensive nature of the program guarantees that each participant receives customized assistance tailored to their particular circumstances. If you seek outpatient addiction recovery services that emphasize personal care along with effective treatment strategies, this center is ready to assist you.

Outer Cape Health Services

Situated in Wellfleet, MA, Outer Cape Health Services delivers extensive support for addiction recovery, serving both adults and adolescents. The facility offers a spectrum of care, including detox services, broader substance use disorder treatment, and dedicated programs for those facing concurrent mental health and addiction challenges. Their therapeutic offerings encompass intensive outpatient, standard outpatient, and outpatient detox programs. Treatment methodologies employed are grounded in proven techniques like 12-step facilitation, motivational interviewing, and cognitive behavioral therapy. Distinctive programs are available for adult men, adult women, and individuals impacted by intimate partner or domestic abuse. Committed to high standards of care, Outer Cape Health Services crafts personalized recovery plans to guide individuals toward lasting sobriety.

Outreach Development Corporation

Outreach Development Corporation, located in Richmond Hill, NY, delivers extensive treatment for substance use and specialized support for those facing concurrent mental health challenges. The center offers various outpatient services, such as outpatient methadone/buprenorphine or naltrexone therapies, alongside standard outpatient care. It emphasizes techniques like anger management, brief interventions, and cognitive behavioral therapy. Catering to both adults and seniors, there are also tailored programs available for younger individuals and those with trauma backgrounds. Outreach Development Corporation prioritizes personalized care and assistance for all clients, ensuring a high standard of rehabilitation services for both men and women.

Outreach Development Corporation

Outreach Development Corporation, situated in Brooklyn, NY, delivers extensive outpatient addiction treatment for individuals of all ages. Their expertise lies in facilitating 12-step programs, teaching anger management techniques, and utilizing cognitive behavioral therapy to create personalized recovery plans for those affected by substance use disorders. The center uniquely supports adolescents, survivors of domestic violence, intimate partner violence, and sexual abuse. Catering to both men and women, they provide outpatient services including methadone/buprenorphine or naltrexone treatment alongside general outpatient care. Committed to high-quality, evidence-backed strategies, Outreach Development Corporation is devoted to assisting people in their path to wellness.

Outreach Outpatient Services (OOS)

Outreach Outpatient Services (OOS) situated in Richmond Hill, NY, provides an extensive range of drug treatment options via outpatient methods like methadone/buprenorphine or naltrexone therapies. Emphasizing anger management techniques, short interventions, and cognitive behavioral strategies, this center specializes in delivering support to active military members, teenagers, and men. OOS accommodates both adults and younger clients, welcoming individuals across the gender spectrum. With customized treatment plans and exceptional care standards, the center stands out as an excellent option for anyone in need of effective and individualized rehabilitation services.

Outreach Development Corporation

The Outreach Development Corporation, located in Bellport, NY, specializes in outpatient services aimed at addressing substance use disorders and co-occurring mental health issues in adults and emotional disturbances in children. This center provides various programs including outpatient day treatment, partial hospitalization, and medications like methadone, buprenorphine, or naltrexone. With a strong emphasis on techniques such as anger management, brief intervention, and cognitive behavioral therapy, it particularly supports adult women who have faced issues like intimate partner violence, domestic violence, or sexual trauma. Catering to adults, seniors, and young adults, their approach is tailored to women, ensuring high-quality care and distinctive assistance for those requiring specialized treatment.

Outreach Development Corporation

Nestled in Bellport, NY, Outreach Development Corporation provides complete care for adults struggling with addiction and co-occurring severe mental health conditions. Their outpatient offerings encompass individualized support for adults and young people, featuring distinct programs for men and women. Employing proven methods like cognitive behavioral therapy and anger management, the center also administers outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. Dedicated to superior care and customized treatment paths, Outreach Development Corporation is committed to guiding individuals toward sustained wellness through brief, targeted interventions and personalized therapeutic approaches.

Outreach Recovery II

Outreach Recovery II, located in Frederick, MD, specializes in treating adults with substance use disorders, including those experiencing concurrent severe mental health issues or emotional challenges in children. The center offers a range of programs, including intensive outpatient care and standard outpatient services, as well as treatments using methadone, buprenorphine, or naltrexone. Emphasizing methodologies such as 12-step facilitation, anger management, and brief interventions, the facility serves active duty military members, as well as adult men and women. It also features services for children and adolescents, with programs specifically designed for each gender. Outreach Recovery II is committed to providing high-quality care that meets the unique needs of each individual.

Outpatient Addiction Recovery Services

Outpatient Addiction Recovery Services in Pittsburgh, PA, provides a well-rounded approach to substance use treatment via outpatient programs that include methadone/buprenorphine and naltrexone options. This center is dedicated to delivering tailored care for adults, including both men and women, as well as active duty military members. By adopting a holistic methodology, the facility aims to facilitate recovery for individuals in their journey. Outpatient Addiction Recovery Services is distinguished by its dedication to quality care and personalized treatment strategies. For those in search of effective outpatient addiction solutions, this center presents a variety of specialized programs designed to address a wide range of needs.

Outreach Community Care Network

The Outreach Community Care Network located in Daytona Beach, FL delivers extensive outpatient services for adults dealing with substance use and significant mental health challenges, along with support for emotional issues in youth. This center features targeted programs designed to meet personal requirements, utilizing various evidence-supported methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. Catering to adults, young adults, and children across the gender spectrum, the center offers outpatient treatments with methadone, buprenorphine, or naltrexone, ensuring high-quality support for individuals pursuing recovery.

Outreach Development Corporation

Situated in Brentwood, NY, Outreach Development Corporation specializes in treatment programs for substance use disorders. The center offers a range of outpatient services, including methadone/buprenorphine or naltrexone therapies, standard outpatient services, and diverse treatment modalities like anger management, brief intervention, and cognitive behavioral therapy. Their tailored programs are designed for adult males, adult females, and those who have faced intimate partner or domestic violence. Catering to adults and young adults of all genders, this facility prioritizes high-quality care through customized treatment plans. For those in search of effective and tailored addiction recovery solutions, this center is committed to guiding you on your path to healing.

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In Roosevelt, NY, the Outreach REACT Center delivers focused outpatient care for adults and children battling substance use disorders, alongside co-occurring mental health challenges. Their services employ proven methods like anger management, cognitive behavioral therapy, and brief intervention techniques. They offer customized programs designed for adult men and women, as well as those who have gone through traumatic experiences. Catering to adults and young adults across all gender identities, the center prioritizes high-quality treatment and personalized recovery journeys. The Outreach REACT Center provides outpatient medication management, including methadone/buprenorphine or naltrexone, to assist individuals in their journey toward lasting recovery.

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Overlook Medical Center, located in Summit, NJ, provides extensive substance use rehabilitation for both adults and children facing significant mental health challenges. The center's offerings include intensive outpatient programs, regular outpatient services, and targeted treatments involving methadone/buprenorphine or naltrexone. Utilizing evidence-driven techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, it accommodates a diverse clientele. The center features specialized programs designed for adult men, adult women, and survivors of sexual abuse. Overlook Medical Center is dedicated to delivering quality care for adults and young adults of all genders, ensuring that treatment is personalized to meet the unique needs of each individual. It stands out as an excellent option for those pursuing a comprehensive recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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