Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.
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The Oxford Outpatient Treatment Center, situated in Oxford, MS, delivers a full spectrum of specialized care for individuals navigating substance use recovery. This center provides intensive outpatient programs, day treatment services, and supported living accommodations tailored for adults and young adults. Employing proven therapeutic strategies including cognitive behavioral therapy and anger management, the program emphasizes 12-step integration. The Oxford Outpatient Treatment Center is particularly adept at addressing the complex needs of those with dual diagnoses of mental health and substance use challenges, serving both men and women who are looking for effective treatment within a nurturing setting.
Situated in Etta, MS, Oxford Treatment Center provides extended residential care and round-the-clock programs for detoxification and addiction therapy. This facility features tailored services for clients who have faced trauma, those living with HIV or AIDS, and individuals with both mental health and substance use disorders. The center serves adults and young adults of all genders. Employing methods such as 12-step facilitation, anger management, and cognitive behavioral therapy, Oxford Treatment Center focuses on delivering high-quality care to assist individuals in their path to recovery.
PATHways Program UK Healthcare in Lexington, KY, delivers extensive outpatient services for individuals struggling with addiction, co-occurring mental health conditions, and trauma. The center focuses on the unique challenges of intimate partner violence, sexual abuse, and trauma, offering personalized treatment plans specifically designed for adult and senior women. Utilizing a range of therapeutic modalities, including 12-step facilitation, brief intervention, and cognitive behavioral therapy, they ensure each client receives care tailored to their individual needs. Their offerings encompass outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside ongoing outpatient counseling. PATHways Program UK Healthcare is committed to offering exceptional, empathetic support to help clients achieve lasting recovery.
PAX Riverbend in Jeffersonville, IN, delivers targeted substance use therapy for adults and young adults managing co-occurring severe mental health conditions or emotional challenges. The facility features intensive outpatient, outpatient, and partial hospitalization programs. Emphasizing personalized care, their approach includes 12-step facilitation, anger management techniques, and brief intervention strategies. Serving both men and women, PAX Riverbend offers a holistic path to recovery. What distinguishes this center is its commitment to customized treatment strategies, dedicated to offering excellent care and assistance to those pursuing freedom from addiction and improved mental well-being.
PORT Health Services, located in Greenville, NC, provides outpatient treatment for substance use and co-occurring disorders for both adults and children. The center offers various programs, including outpatient day treatment and partial hospitalization. It employs techniques such as anger management, brief interventions, and cognitive behavioral therapy to support clients of all genders and ages, including teenagers and young adults. Additionally, tailored programs are available to tackle issues related to intimate partner violence, domestic abuse, and sexual trauma. Committed to delivering high-quality, personalized care, this center is an essential resource for individuals looking for thorough rehabilitation services in Greenville.
PORT Health Services, located in Morehead City, NC, provides a thorough approach to substance use treatment for both adults and children facing co-existing mental health challenges. The center features various options, including intensive outpatient programs and outpatient services, alongside targeted treatments that incorporate methadone, buprenorphine, or naltrexone. Emphasizing strategies such as cognitive behavioral therapy and anger management, PORT Health Services addresses the needs of clients dealing with dual diagnoses as well as substance use disorders related to pain. The facility offers dedicated care for men and women alike, ensuring individuals can access effective, evidence-based rehabilitation programs within a nurturing setting.
PORT Health Services, located in New Bern, NC, provides a wide array of treatment options for substance use and co-occurring disorders designed for both adults and children. Their services include intensive outpatient programs, outpatient care, and day treatment that utilize proven methods such as cognitive behavioral therapy and motivational incentives. The center offers tailored support for adult women and caters to a diverse age group, emphasizing young adults. With a commitment to personalized treatment plans and a nurturing atmosphere, PORT Health Services aims to assist clients in attaining sustainable recovery. Both male and female clientele can anticipate exceptional, customized care at this facility.
PA Associates LLC, located in Mount Pocono, PA, provides outpatient detox and substance abuse treatment options for both adults and young adults. This center is known for its expertise in motivational interviewing, relapse prevention, and counseling for substance use disorders. With customized services geared toward men and women, it creates a nurturing atmosphere conducive to recovery. The offerings include outpatient treatment with methadone, buprenorphine, or naltrexone. PA Associates LLC emphasizes personalized care to support clients in attaining long-term sobriety. Whether you require detox services or continuous support, this facility delivers extensive programs for all patients.
Situated in Joplin, MO, Ozark Center delivers a wide range of rehabilitation services designed for individuals dealing with substance abuse issues and concurrent mental health challenges. The facility offers various treatment options, including intensive outpatient care, outpatient day programs, and partial hospitalization. Emphasizing evidence-based practices like cognitive behavioral therapy and anger management, Ozark Center addresses the specific needs of adult men and women, including active military members. Their focused programs for young adults and adults, along with a gender-responsive approach, guarantee personalized and high-quality support for individuals striving for recovery from addiction and mental wellness issues.
Ozark Center, situated in Joplin, MO, is dedicated to providing targeted recovery support for adults and young adults. This establishment features comprehensive programs including intensive outpatient, day treatment, and partial hospitalization options for individuals managing substance use challenges and co-occurring mental health concerns. Employing strategies such as cognitive behavioral therapy, anger management techniques, and brief intervention methods, Ozark Center crafts personalized treatment plans. Specialized care is extended through distinct programs designed for adult men, adult women, and those with trauma histories, ensuring a holistic approach. Open to both male and female individuals, the center is committed to delivering high-quality services to foster lasting recovery.
In Rockport, Maine, the PARC Program offers extensive recovery support for adults and young adults facing challenges with addiction and intertwined mental health conditions. This center provides inpatient hospital detox, therapeutic interventions, and round-the-clock supervision, featuring tailored programs for individuals with co-occurring disorders. Their treatment methodologies incorporate 12-step principles, emotional regulation strategies, and short-term intervention methods. Dedicated to personalized support, the PARC Program serves both male and female individuals, fostering a welcoming and affirming atmosphere. Discover exceptional support and custom treatment at this respected recovery facility.
The Owyhee Community Health Facility, situated in Owyhee, NV, delivers extensive outpatient services for adults grappling with substance use disorders and co-occurring severe mental health conditions, as well as children experiencing serious emotional disturbances. This center features targeted interventions for young people and serves a diverse clientele including adults, children and adolescents, and older adults across all genders. Employing therapeutic methods such as 12-step facilitation, anger management, and brief intervention strategies, the Owyhee Community Health Facility is dedicated to providing high-quality care to everyone pursuing recovery from addiction. Their offerings also encompass outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care.
Ozark Center/New Directions, situated in Joplin, MO, delivers a full spectrum of targeted recovery support. This establishment addresses needs including detox, addiction treatment, and support for those with intertwined substance abuse and severe mental health conditions. Their care modalities encompass inpatient detox, round-the-clock residential stays, and brief residential stays. The center utilizes proven therapeutic methods such as 12-step integration, motivational interviewing, and cognitive-behavioral therapy. Offering distinct programs for adult males, adult females, and individuals affected by trauma, Ozark Center/New Directions serves adult and young adult populations of all genders. Individuals pursuing effective care within an encouraging setting will discover this center to be a significant aid in their path to wellness.
PBMHR Region XII, situated in Summit, MS, is dedicated to providing extensive treatment for substance use disorders, including cases where these issues coincide with serious mental health conditions in adults or significant emotional disturbances in children. The center emphasizes personalized care and offers a range of options such as intensive outpatient programs, regular outpatient services, and specific treatments involving methadone, buprenorphine, or naltrexone. Employing scientifically supported methods like cognitive behavioral therapy, brief interventions, and anger management, PBMHR Region XII serves individuals of all ages and genders. It is distinguished by its customized programs and focus on high-quality care for those addressing challenges related to addiction and mental health.
Situated in Santa Ana, CA, PES/EBS Inc is dedicated to delivering targeted addiction treatment programs for both adults and young adults. This center features intensive outpatient treatment, along with a variety of outpatient services, including methadone, buprenorphine, and naltrexone options. Utilizing evidence-based methodologies, the facility emphasizes interventions such as brief intervention, cognitive behavioral therapy, and the Matrix Model. PES/EBS Inc prides itself on providing high-quality care to all clients, including those who may be navigating the criminal justice system. The center is committed to offering personalized support and effective solutions for individuals striving to overcome substance use challenges.
Ozark Center, situated in Lamar, MO, provides outpatient treatment for substance abuse as well as specialized care for adults facing serious mental health challenges or emotional disturbances in children. The center employs regular outpatient services that include brief interventions and strategies aimed at preventing relapse. Furthermore, Ozark Center enhances accessibility through telemedicine and telehealth services. With specific programs designed for adult men, women, and individuals who have encountered trauma, the facility addresses the needs of a varied clientele. Catering to both adult and young adult populations of any gender, Ozark Center emphasizes personalized care and effective treatment to foster long-term recovery.
Situated in Neosho, MO, Ozark Center/New Directions stands out as a prominent establishment providing outpatient treatment for substance use issues among adults and young adults. The center excels in addressing dual diagnoses that include substance use disorders and severe mental health challenges for adults, as well as emotional issues in children. Emphasizing personalized treatment plans, the facility employs proven methods like brief intervention, cognitive behavioral therapy, and the Matrix Model. Tailored programs are available for adult men, women, and individuals who have endured trauma. Committed to delivering high-quality care, this center specializes in support and recovery resources for both male and female clients.
The PAAR Center, situated in Porterville, CA, specializes in extended residential care for adult men battling substance use disorders. This establishment offers various levels of support including transitional living, halfway house accommodations, and sober living environments. Their therapeutic model incorporates 12-step principles, anger management techniques, and cognitive behavioral therapy, specifically designed for men who have endured intimate partner violence, domestic abuse, or sexual trauma. Serving adults, seniors, and young adult males, the center is committed to delivering exceptional treatment within a nurturing setting. For individuals requiring in-depth recovery programs adapted to unique circumstances, the PAAR Center stands ready to assist in their path to lasting sobriety.
The PAC Program of the Bronx Inc, situated in Bronx, NY, delivers extensive substance use care for individuals of all ages. They excel in addressing dual diagnoses, specifically co-occurring substance use and significant mental health conditions or emotional challenges. Their treatment offerings include intensive outpatient, standard outpatient, and regular outpatient services. The program emphasizes anger management, brief interventions, and cognitive behavioral therapy, serving adult men, adult women, and survivors of intimate partner or domestic violence. Providing specialized support for both genders, the center is dedicated to delivering personalized, top-tier treatment to foster lasting recovery and overall wellness.
PBMHR Region XII, situated in Moselle, MS, provides exceptional rehabilitation care for adults and young adults facing challenges with substance abuse and co-occurring mental health conditions. The center features tailored programs for adult men, adult women, and individuals who have experienced intimate partner violence, fostering a secure and nurturing atmosphere for recovery. Their treatment offerings encompass residential and short-term residential stays, employing proven therapeutic methods such as 12-step facilitation, anger management, and brief intervention strategies. PBMHR Region XII's dedication to personalized treatment and overall wellness establishes it as a reliable provider of thorough addiction recovery.
In Hattiesburg, Mississippi, the PBMHR Region XII center provides outpatient care for individuals battling substance use disorders. The facility focuses on adults and young adults, with a particular expertise in addressing the complexities of dual diagnoses, encompassing both substance use alongside serious mental health conditions in adults or emotional challenges in children. Utilizing proven therapeutic methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, PBMHR Region XII delivers structured outpatient treatment designed for positive outcomes. The center offers specialized services targeting the unique needs of adult men, adult women, and individuals experiencing co-occurring mental health and substance use issues, ensuring a personalized approach to recovery. PBMHR Region XII is dedicated to offering high-quality, individualized rehabilitation services.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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