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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Phoenix Counseling Center

At Phoenix Counseling Center in Gastonia, NC, we provide comprehensive, evidence-based therapies for individuals of all ages struggling with addiction and co-occurring mental health issues. Our treatment options include intensive outpatient care, day treatment, and partial hospitalization. We employ proven strategies such as 12-step facilitation, anger management techniques, and brief intervention methods. Phoenix Counseling Center is equipped to support specific groups, including active military personnel, teenagers, and adult men. We welcome both male and female clients, offering a supportive environment for every stage of recovery. Our dedication to high-quality, personalized care makes us a leading facility for those pursuing lasting sobriety and mental wellness.

Phoenix House
Venice, CA

Phoenix House, situated in Venice, CA, delivers targeted substance use recovery for adult males grappling with co-occurring serious mental health conditions or emotional challenges. This center offers extended residential stays, day treatment programs, and outpatient medication-assisted treatment including methadone, buprenorphine, or naltrexone. Emphasizing 12-step integration, emotional regulation techniques, and concise therapeutic strategies, Phoenix House crafts individualized pathways for individuals with trauma histories or those connected to the legal system. Catering to adults, older adults, and younger adults, the center ensures compassionate support within a setting uniquely structured for men pursuing sobriety.

Phoenix House
Hauppauge, NY

At Phoenix House in Hauppauge, NY, a full spectrum of addiction recovery solutions is available. This includes medically supervised detox, therapeutic interventions for substance dependence, and dedicated support for those facing the dual challenges of addiction and significant mental health conditions. The center provides inpatient hospital-level detox, comprehensive treatment, and round-the-clock supervision, employing proven methods like 12-step program integration, anger management techniques, and brief counseling strategies. Primarily serving adult men, Phoenix House extends its services to adults of all ages, including seniors and young adults. Its programs are designed with gender-specific considerations to offer optimal support for its male clientele. Phoenix House is committed to delivering high-caliber care and individualized recovery plans to guide individuals toward sustained sobriety.

Phoenix House
Santa Ana, CA

Phoenix House, situated in Santa Ana, CA, delivers a complete spectrum of recovery services for those battling addiction and co-occurring psychological challenges. Their offerings include intensive outpatient, extended residential stays, and standard outpatient care, all grounded in proven methods such as cognitive behavioral therapy and anger management. Phoenix House supports adult men and women, along with individuals who have faced intimate partner abuse. Emphasizing personalized support, this center is open to adults and young adults, fostering a nurturing space for healing and personal development. For those in search of tailored care in a kind and understanding atmosphere, Phoenix House is committed to guiding you toward sustained wellness.

Phoenix Recovery Center LLC

Phoenix Recovery Center LLC, located in South Jordan, UT, specializes in extensive treatment options for detoxification, addiction, and co-occurring mental health issues in both adults and children. The center features various programs including hospital inpatient services, intensive outpatient treatment, and specialized care for men, women, and individuals affected by intimate partner violence, ensuring personalized support for diverse needs. Employing methods such as 12-step facilitation, anger management, and brief intervention strategies, the center emphasizes custom treatment plans. Catering to adults and young adults of all genders, Phoenix Recovery Center LLC commits to providing exceptional care in a nurturing setting for individuals on their path to recovery from substance use.

Phoenix VA Healthcare System

Phoenix VA Healthcare System, situated in Phoenix, AZ, provides extensive addiction recovery care for adults, particularly those with co-occurring substance use and severe mental health issues, within a residential framework. The curriculum incorporates diverse therapeutic modalities such as 12-step support, emotional regulation training, and short-term counseling. This facility is equipped to serve distinct populations, including adult men, adult women, and individuals with trauma histories, thereby accommodating a wide spectrum of needs. Offering extended residential stays, shorter programs, and round-the-clock care, the center is committed to tailoring treatment to individual requirements. The Phoenix VA Healthcare System, which supports adult men, adult women, and younger adults, delivers exceptional recovery support in a nurturing atmosphere.

Phoenix House Florida Residential Ctr

Phoenix House Florida Residential Center, located in Citra, FL, delivers extensive substance abuse rehabilitation for adults and adolescents grappling with co-occurring serious mental health conditions or emotional challenges. This institution features long-term, short-term, and round-the-clock residential options, delivering personalized support through methodologies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. Tailored services are available for adult men and women, survivors of intimate partner violence, and individuals of all gender identities. Renowned for its high standards of care and customized treatment strategies, Phoenix House Florida Residential Center stands out as a premier destination for individuals pursuing effective and empathetic recovery within a nurturing setting.

Phoenix House Florida

Phoenix House Florida, located in Brandon, FL, provides in-depth substance use treatment for adults, including those facing significant mental health challenges. The center features both intensive outpatient and outpatient programs, designed specifically for adolescents, men, and women. Various treatment methods are employed, such as 12-step facilitation, anger management, and brief intervention strategies. This facility serves both genders, offering outpatient options for methadone, buprenorphine, or naltrexone therapy. With an emphasis on personalized care and effective programs, Phoenix House Florida stands out as a key resource for individuals in need of rehabilitation services in the Brandon region.

Piedmont Community Services

Piedmont Community Services, located in Martinsville, VA, provides thorough outpatient treatment for substance use disorders in both adults and children facing concurrent severe mental health issues. The center features targeted programs designed for adult males, females, and clients involved in the criminal justice system, addressing a variety of client requirements. By employing proven methods such as 12-step programs, anger management techniques, and cognitive behavioral therapy, they deliver personalized treatment solutions. Their outpatient services also include methadone, buprenorphine, and naltrexone therapies, promoting an ongoing support system. Catering to adults and seniors of any gender, Piedmont Community Services emphasizes high-quality care for those on their path to recovery.

Phoenix Behavioral Health LLC

Phoenix Behavioral Health LLC in Cherry Hill, NJ, provides extensive care for individuals battling addiction. They offer various levels of support, including intensive outpatient, standard outpatient, and partial hospitalization programs. The facility focuses on substance use disorders and co-occurring mental health conditions. Their therapeutic methods include 12-step facilitation, anger management strategies, and brief intervention techniques. Phoenix Behavioral Health LLC is dedicated to offering personalized recovery plans, with specific options available for active duty military personnel, adult men, and adult women. They welcome both male and female clients, fostering a welcoming atmosphere for everyone on their journey to sobriety.

Phoenix Behavioral Health LLC

Phoenix Behavioral Health LLC in Trenton, NJ delivers targeted recovery support for individuals grappling with addiction and co-occurring mental health conditions, serving both youth and adults. Their offerings encompass intensive outpatient, standard outpatient, and partial hospitalization treatment plans, employing proven therapeutic modalities such as 12-step engagement and emotional regulation techniques. The center is equipped to provide customized care for active military personnel, adult males, and females. By offering individualized services to adults and young adults across the gender spectrum, Phoenix Behavioral Health LLC in Trenton distinguishes itself through its thorough and personalized approach to recovery, presenting a leading option for those in pursuit of impactful and empathetic substance abuse treatment.

Philio Inc
Toledo, OH

Philio Inc, situated in Toledo, OH, provides an extensive array of rehabilitation services aimed at treating substance use disorders alongside co-occurring mental health conditions for both adults and children. The center features intensive outpatient programs, outpatient day programs, and partial hospitalization options. Philio Inc employs various therapeutic methods including 12-step facilitation, anger management techniques, and brief interventions to support its diverse clientele, which includes active military members, adolescents, and adult males. With gender-specific programs designed to meet diverse needs, this facility is dedicated to providing customized care for every individual. Their focus on delivering high-quality treatment and a broad spectrum of services positions Philio Inc as an excellent option for those in search of effective and personalized rehabilitation solutions.

Phoenix Center
Greenville, SC

Situated in Greenville, SC, the Phoenix Center delivers a complete range of addiction recovery solutions for adults and adolescents. This establishment offers extended stay residential programs, inpatient detoxification, and continuous round-the-clock support. Their therapeutic methodologies encompass 12-step integration, cognitive behavioral techniques, and the Matrix Model. Emphasizing personalized attention, the Phoenix Center welcomes individuals of all genders. For those in search of a nurturing setting for detox and substance use rehabilitation, this center's excellent offerings and tailored methods could be instrumental in your journey toward lasting sobriety.

Phoenix House Florida

Phoenix House Florida in Tampa, FL, delivers extensive addiction and co-occurring mental health treatment for individuals of all ages. The program features intensive outpatient and traditional outpatient options, incorporating medication-assisted treatment such as methadone, buprenorphine, or naltrexone. Tailored programs are available for teenagers, adult men, and women. Treatment modalities include 12-step facilitation, anger management, and brief interventions, all designed for personalized recovery journeys. Phoenix House Florida is dedicated to providing effective care for both male and female patients navigating addiction and mental health issues.

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Greenville, SC

Nestled in Greenville, SC, the Phoenix Center delivers complete addiction treatment and interim housing for adult women, older adults, and younger individuals. This establishment caters to individuals facing dual diagnoses of mental health and substance use disorders, alongside pregnant and new mothers. Their treatment options encompass extended residential stays, partial hospitalization, and standard outpatient care. Utilizing proven methods like 12-step integration, emotional regulation training, and concise therapeutic interventions, the Phoenix Center aims for successful recovery. Prioritizing excellent care and personalized assistance, the Phoenix Center is a reliable choice for those pursuing well-rounded recovery services.

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Greenville, SC

In Greenville, SC, the Phoenix Center delivers complete addiction recovery services designed for each person's unique situation. Their offerings include high-intensity outpatient care, standard outpatient services, and targeted treatments using methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, strategies for managing anger, and brief intervention techniques, the center supports active military, teens, and adult men. The Phoenix Center provides individualized support for adults and young people, accommodating both male and female patients. Discover excellent, customized recovery solutions at this respected treatment facility.

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Phoenix Counseling Center, situated in Shelby, NC, specializes in providing a wide range of rehabilitation services for both adults and young adults struggling with substance use disorders alongside mental health challenges. The center features a residential detox program and round-the-clock treatment options that emphasize 12-step methods, anger management techniques, and short-term intervention strategies. What sets Phoenix Counseling Center apart is its tailored programs designed for active duty service members, as well as specific services for adult men and women. This facility is dedicated to delivering quality care and personalized addiction treatment solutions for clients of all genders.

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Nestled in Shelby, NC, Phoenix Counseling Center delivers a broad spectrum of all-encompassing recovery solutions. This facility excels in addressing addiction and dual diagnoses for individuals of all ages, offering intensive outpatient care, daytime outpatient services, and partial hospitalization options. Employing strategies like 12-step guidance, anger control techniques, and brief intervention methods, the center supports active military members, adult men, and women. Phoenix Counseling Center is committed to delivering excellent treatment within a nurturing and inclusive setting for adults and young adults across the gender spectrum.

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Ronkonkoma, NY

Phoenix House in Ronkonkoma, NY, provides extensive residential rehabilitation for adults struggling with addiction, co-occurring mental health disorders, and children facing emotional challenges. They cater to specific needs with programs for adult men, women, and survivors of domestic abuse. Residents receive continuous support in a nurturing setting. Their treatment strategies include proven methods like 12-step support and anger management techniques, along with short-term counseling options. Phoenix House is dedicated to delivering personalized care for adults and young adults, aiming for enduring recovery.

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Located in Calumet, MI, Phoenix House Inc specializes in rehabilitation for substance use disorders, offering transitional and sober living environments. The center provides customized treatment plans for adults dealing with co-occurring substance use and significant mental health issues, as well as emotional challenges in children. Treatment modalities include extensive residential programs and outpatient options that utilize 12-step approaches, cognitive behavioral therapy, and short-term interventions. Phoenix House Inc focuses on serving adult men, young adults, and seniors, particularly those who have faced intimate partner violence. Renowned for its high standards of care, the facility also welcomes active duty military personnel in need of recovery support.

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Phoenix Houses of Long Island City in Astoria, NY, delivers complete care for individuals of all ages struggling with addiction and co-occurring mental health issues. This center features hospital-level inpatient detox and treatment programs that emphasize 12-step facilitation, anger management, and brief intervention strategies. Dedicated programs are available for adult men and women, addressing a wide range of requirements. The facility is dedicated to personalized treatment plans and scientifically supported methods, ensuring effective recovery support for all clients in a nurturing setting.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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