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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Praxis of Carmel by Landmark Recovery

Situated in Carmel, IN, Praxis of Carmel by Landmark Recovery delivers an extensive array of services aimed at treating addiction for both adults and younger individuals. The center specializes in detoxification, substance abuse management, and focused care for individuals dealing with both substance use disorders and significant mental health challenges in adults, as well as emotional disturbances in youth. Treatment options range from intensive outpatient and long-term residential to outpatient services. Praxis of Carmel employs evidence-based methodologies such as 12-step programs, brief interventions, and cognitive behavioral therapy. Additionally, it features customized plans for active military members, as well as distinct programs for men and women. Committed to personalized care, this center provides a superior rehabilitation journey for those pursuing recovery.

Praxis of South Bend

Praxis of South Bend, situated in Mishawaka, IN, delivers a full spectrum of recovery support. This establishment features detoxification, treatment for substance reliance, and focused assistance for individuals experiencing co-occurring mental health and addiction challenges, as well as children with emotional distress. Offering a variety of treatment modalities like intensive outpatient, extended residential stays, and standard outpatient care, the center serves adults and young adults across the gender spectrum. Praxis of South Bend employs scientifically proven methods such as 12-step integration, motivational interviewing, and cognitive behavioral therapy to deliver exceptional treatment. Dedicated programs are provided for active service members, adult males, and adult females, positioning this center as a flexible and supportive destination for those pursuing recovery.

Praxis of the Firelands

Praxis of the Firelands, situated in Willard, OH, delivers extensive recovery support for adults and younger adults confronting addiction and co-occurring psychological challenges. The facility offers hospital-based inpatient detox and treatment, ensuring round-the-clock medical attention. Distinct programs are available for active military members, adult men, and women, addressing a spectrum of specific needs. Employing methods like 12-step encouragement, emotional regulation strategies, and short-term interventions, Praxis of the Firelands ensures high-quality, personalized care. Welcoming both male and female individuals, this establishment represents a promising pathway to successful and empathetic addiction recovery.

Prairie View Inc
McPherson, KS

Prairie View Inc, located in McPherson, KS, specializes in extensive treatment programs for individuals experiencing substance use challenges alongside mental health disorders. This center offers a variety of outpatient services, such as methadone and buprenorphine therapy, as well as cognitive behavioral approaches. It is dedicated to providing care that addresses anger management and is rooted in trauma-informed practices, effectively supporting clients with diverse and intricate needs. With a commitment to personalized treatment, Prairie View Inc accommodates both men and women through specialized programs designed for different age demographics. Those in pursuit of quality, research-backed care will discover empathetic and impactful services at this center.

Prairie View Inc
Hillsboro, KS

Prairie View Inc, situated in Hillsboro, KS, delivers extensive outpatient services for adults and children facing substance use and intertwined mental health conditions. The facility features tailored interventions for those with trauma histories and dual diagnoses. Employing proven methods such as cognitive behavioral therapy and anger management, Prairie View Inc guides individuals through their healing process. By offering gender-specific and age-appropriate services, the center guarantees personalized attention for everyone in need of support. From standard outpatient care to medication-assisted treatment with methadone or buprenorphine, Prairie View Inc is dedicated to superior, all-encompassing recovery for its clientele.

Prairie View Inc

Prairie View Inc, situated in Newton, KS, provides thorough outpatient services for individuals of all ages struggling with substance use and related mental health conditions. Their approach incorporates proven methods such as cognitive behavioral therapy and anger management, with a specific focus on assisting clients who have faced trauma. The center offers tailored programs for those with dual diagnoses, serving adult men and women, as well as young people. Patients can anticipate personalized, high-caliber support, whether they require standard outpatient care or medication-assisted treatment like methadone or buprenorphine.

Pratt Community Health Clinic LLC

Pratt Community Health Clinic LLC located in Pratt, KS, presents an extensive array of services for those seeking help with addiction. This facility offers detox services, treatment for substance use, and targeted support for individuals facing both substance use issues and significant mental health challenges. Various treatment options are available, including long-term residential care, outpatient programs, and outpatient detoxification services. Utilizing strategies like brief intervention, motivational interviewing, and contingency management, the clinic customizes treatment plans according to each person's specific requirements. Unique programs are available for active duty military members, adolescents, and adult men. Pratt Community Health Clinic LLC emphasizes high-quality care and employs evidence-based methods to facilitate enduring recovery for adults of all genders.

Preferred Behavioral Health of NJ

Preferred Behavioral Health of NJ, located in Barnegat, NJ, delivers extensive treatment for substance use through personalized programs designed to meet unique requirements. The center focuses on intensive outpatient programs, outpatient services, and outpatient treatment options involving methadone, buprenorphine, or naltrexone. Various methodologies are implemented, including 12-step programs, anger management, and short-term interventions. The facility features specialized programs aimed at active duty military personnel, adult males, and adult females, addressing a wide range of needs. By providing care to adults and young adults across genders, the center is dedicated to offering effective support and assistance for individuals pursuing recovery from substance use challenges.

Preferred Family Healthcare Inc

Preferred Family Healthcare Inc, located in Kansas City, MO, specializes in substance use treatment aimed at both adults and young adults struggling with significant mental health challenges. The center offers various services, including intensive outpatient programs and options for outpatient methadone, buprenorphine, or naltrexone treatment. Their treatment methodology incorporates 12-step support, anger management strategies, and brief intervention methods. This facility primarily serves adult men but also provides programs designed for women. Committed to delivering high-quality, personalized care, this center is an essential resource for individuals looking for thorough addiction recovery solutions in the Kansas City region.

Preferred Family Healthcare Inc

Preferred Family Healthcare Inc, located in Kirksville, MO, provides an extensive array of services for substance use treatment. This center offers outpatient services, regular outpatient programs, and residential care available around the clock. Emphasizing 12-step support, anger management strategies, and short intervention techniques, it is designed for adults facing simultaneous substance use issues and serious mental health conditions. Additionally, the facility has specialized programs tailored for adolescents, along with services for adult men and women. Catering to both adults and youth, it ensures gender-specific support for male and female clients. Renowned for its high standards of care, Preferred Family Healthcare Inc is committed to delivering customized treatment to individuals on their path to recovery.

Preferred Family Healthcare Inc

Preferred Family Healthcare Inc, located in Jefferson City, MO, provides focused treatment for adults dealing with substance use issues, as well as those facing significant mental health challenges simultaneously. Their customized offerings feature intensive outpatient services, 12-step support, anger management courses, and brief intervention strategies. The center also delivers outpatient treatment options, including methadone/buprenorphine or naltrexone, for those pursuing medication-assisted recovery. What sets this facility apart is its dedicated programs for adult men and women, catering to their unique requirements. Aimed at both adult and young adult clients, regardless of gender, this center ensures a thorough support system to aid individuals in their recovery process.

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Power House Psychotherapy and Add LLC, situated in Newark, NJ, provides comprehensive outpatient and intensive outpatient services for individuals of all ages battling substance use and co-occurring mental health conditions. Their specialized approach incorporates expertise in areas such as anger management, brief intervention strategies, and cognitive behavioral therapy. The center is particularly adept at serving active duty military personnel, adolescents, and adult men. Furthermore, they offer distinct programs designed for adults and seniors, embracing all genders. This facility is distinguished by its customized treatment plans and dedication to delivering high-quality care, whether through outpatient day programs or partial hospitalization options.

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Practical Recovery Psychology Group in La Jolla, CA, provides extensive recovery programs for adults and older individuals facing addiction and related mental health challenges. Their offerings include robust outpatient treatment, standard outpatient services, and detox programs administered on an outpatient basis. Treatment methodologies encompass anger management techniques, targeted brief interventions, and cognitive behavioral therapy. The center emphasizes a personalized approach, customizing recovery plans to suit each individual's unique requirements. Both male and female patients receive high-quality care and specialized support at Practical Recovery Psychology Group.

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Situated in Warrenton, MO, Preferred Family Healthcare delivers extensive outpatient services for individuals battling substance use issues, including both adults and young adults. This center is adept at addressing dual diagnosis cases, where substance use disorders coexist with significant mental health challenges or emotional issues. Emphasizing personalized treatment, the facility offers outpatient options like methadone/buprenorphine/naltrexone therapy and structured outpatient programs. The center employs a variety of techniques, such as 12-step programs, anger management strategies, and focused interventions, to create a customized treatment journey for every client. With dedicated initiatives for both men and women, Preferred Family Healthcare is committed to providing high-quality support for those on their path to recovery.

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Preferred Family Healthcare Inc, located in Brookfield, MO, specializes in outpatient treatment for adults and young adults dealing with substance use issues, particularly those who also face significant mental health challenges or emotional struggles. The center offers a variety of regular outpatient programs, including 12-step assistance, anger management courses, and brief intervention strategies. Emphasizing personalized care, this facility serves both men and women, customizing treatment plans to address the unique circumstances of each individual. Experience dedicated care and tailored support at Preferred Family Healthcare Inc, where individuals can embark on a transformative journey toward sustained recovery and improved mental health.

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Preferred Family Healthcare Inc in Moberly, MO, provides extensive outpatient care for substance use disorders. They are particularly adept at assisting individuals managing both addiction and significant mental health challenges. Their treatment strategies include evidence-based methods like 12-step facilitation, anger management, and brief intervention, delivering effective support to adults and young adults. The center also features distinct programs designed for adult men and women, offering gender-specific support. From outpatient methadone/buprenorphine services to general outpatient recovery, the facility adapts to various treatment requirements, emphasizing personalized recovery journeys.

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Preferred Family Healthcare Inc in Saint Charles, MO, delivers extensive treatment options for adults and young adults struggling with substance use disorders alongside significant mental health challenges or emotional issues. The center offers intensive outpatient programs, outpatient services, as well as methadone/buprenorphine and naltrexone treatments. Employing methods such as 12-step support, anger management, and short intervention strategies, this facility serves both men and women, with particular emphasis on support for adult women. With a strong dedication to high-quality care and tailored programs, the center aims to assist individuals in attaining sustainable recovery and enhanced overall health.

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Preferred Family Healthcare Inc, located in Saint Louis, MO, specializes in extensive substance use rehabilitation for both adults and young adults facing significant mental health disorders simultaneously. This center offers various levels of care including intensive outpatient, outpatient, and standard outpatient programs that utilize evidence-supported methodologies like 12-step facilitation, anger management techniques, and brief interventions. With dedicated programs designed for men and women, the facility addresses unique gender-specific requirements. Emphasizing personalized treatment and customized recovery plans, the center is committed to delivering exceptional services for individuals pursuing healing from addiction and mental health issues.

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Preferred Family Healthcare Inc, located in Springfield, MO, specializes in providing tailored substance use treatment programs for both adults and young adults. The facility offers a range of services, including intensive outpatient care, outpatient treatment, and options for methadone/buprenorphine or naltrexone therapy. Emphasizing 12-step facilitation, anger management, and brief intervention methods, the center is dedicated to customizing its programs to fit the unique needs of each individual. With specialized programs for adult women and men, it ensures focused support for all clients. Preferred Family Healthcare Inc is recognized for its dedication to high-quality care and personal treatment approaches, making it a reputable option for individuals seeking rehabilitation in the Springfield region.

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Preferred Family Healthcare Inc located in Hannibal, MO, provides diverse treatment solutions for individuals dealing with substance use and concurrent disorders, addressing both adults and children. The center features intensive outpatient programs, outpatient services, and daytime treatment options. Utilizing methods such as 12-step support, anger management, and short-term interventions, individuals receive personalized care that meets their specific requirements. The facility also offers specialized programs for teenagers, women, and those facing combined mental health challenges. Catering to both men and women, this establishment is dedicated to providing high-quality support to assist individuals in their recovery journey.

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Preferred Family Healthcare Inc in Union, MO, specializes in outpatient services aimed at treating substance use disorders and addressing the complex needs of individuals facing both addiction and serious mental health challenges. The center employs a variety of treatment modalities, such as 12-step programs, anger management strategies, and brief interventions tailored for its clients. It serves a wide demographic, including adolescents and adult men and women, with programs designed to meet the specific needs of each gender. Prioritizing high-quality care, the facility provides outpatient options for methadone/buprenorphine and naltrexone treatment, in addition to routine outpatient services for both adults and younger clients. Those in search of personalized and effective rehabilitation solutions will find comprehensive assistance at this center, which is dedicated to supporting individuals on their path to recovery from addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)