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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Prentice Place
Chicago, IL

Prentice Place located in Chicago, IL, provides targeted treatment for substance use disorders along with transitional housing for adult males. The facility offers both intensive outpatient and regular outpatient programs, incorporating 12-step facilitation, anger management techniques, and cognitive behavioral therapies. Aiming primarily at adult men, including those involved with the criminal justice system, this center addresses their specific needs. Prentice Place is open to adults of all ages, including seniors and younger adults, ensuring personalized care for each client. The dedication to high-quality treatment and specialized services establishes it as a key provider of rehabilitation support in the Chicago region.

Presbyterian Medical Services

Presbyterian Medical Services located in Santa Fe, NM, provides a wide array of outpatient treatment options for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. The center has specialized programs designed for trauma survivors, older adults, and individuals with dual diagnoses, ensuring that each client receives personalized care to meet their specific requirements. The facility employs various therapeutic methods, including anger management, cognitive behavioral therapy, and short-term interventions, emphasizing a holistic approach to healing and sustained recovery. Catering to clients of all genders, across both adult and young adult demographics, this center is committed to offering high-quality, evidence-based interventions that assist individuals in their quest for improved health and well-being.

Prescott House Inc
Prescott, AZ

Prescott House Inc, located in Prescott, Arizona, provides a range of treatment options including intensive outpatient, long-term residential, and outpatient programs specifically for adult men facing challenges with substance misuse and related mental health disorders. The center features a focus on 12-step methods, anger management techniques, and brief intervention strategies. It offers specialized programs for adult men, including those who have experienced sexual abuse or trauma, serving various demographics from young adults to seniors. Prescott House Inc prioritizes personalized care, fostering a nurturing atmosphere conducive to holistic recovery. Committed to delivering high-quality treatment, this facility serves as a symbol of hope for individuals in need of thorough rehabilitation solutions.

Present Moments Recovery

Nestled in Carlsbad, California, Present Moments Recovery delivers all-encompassing substance abuse treatment for adults and adolescents. The center features extended residential stays, encompassing inpatient detox and constant round-the-clock supervision. Tailored offerings exist for active military personnel, adult men, and adult women, addressing a spectrum of requirements. Therapeutic modalities like 12-step guidance, emotional regulation training, and short-term intervention strategies are employed to deliver individualized support. A distinctive aspect of the facility is its dedication to addressing dual diagnoses, including both substance use disorders and significant mental health challenges. Present Moments Recovery is dedicated to delivering superior, gender-exclusive care for those pursuing enduring sobriety.

Present Moments Recovery

Present Moments Recovery in Carlsbad, CA, delivers thorough addiction care designed for each person's specific journey. Their services encompass detox, substance use therapy, and supportive living environments such as halfway houses and sober residences. Employing methods like intensive outpatient, outpatient, and day treatment, clients benefit from targeted support rooted in 12-step principles, anger management techniques, and brief intervention strategies. This establishment supports adult men and women, including those affected by domestic or intimate partner violence. Present Moments Recovery offers excellent, individualized support for adults and young adults of all genders pursuing successful recovery.

Presbyterian Medical Services

Presbyterian Medical Services in Ruidoso, NM, provides extensive outpatient care for individuals dealing with substance abuse issues as well as concurrent mental health concerns in both adults and children. This facility features specialized programs for men and women, as well as clients facing dual diagnoses, ensuring personalized treatment that aligns with each individual's requirements. The center emphasizes holistic recovery through various methodologies, including anger management, cognitive behavioral therapy, and short-term interventions. It offers outpatient treatment options like methadone/buprenorphine or naltrexone, in addition to standard outpatient services, addressing the needs of various ages and genders. Discover exceptional care and guidance on your recovery journey at Presbyterian Medical Services.

Presbyterian Medical Services

Located in Gallup, NM, Presbyterian Medical Services provides targeted outpatient treatment for substance use disorders and co-occurring mental health issues for both adults and young people. Their offerings encompass anger management therapies, cognitive behavioral therapy, and the Matrix Model, ensuring thorough and holistic care. This center develops customized treatment plans to accommodate the needs of male and female clients, including options for regular outpatient care and medications such as methadone, buprenorphine, or naltrexone. Emphasizing high-quality care and personalized strategies, this facility is an essential resource for those seeking effective rehabilitation solutions in the Gallup region.

Preferred Family Healthcare Inc

Preferred Family Healthcare Inc in Saint Charles, MO, provides complete care for individuals struggling with addiction and offers transitional living accommodations. This center excels in addressing dual diagnoses of substance abuse and significant mental health conditions in adults, and severe emotional challenges in children. Their treatment offerings encompass intensive outpatient programs, general outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. They emphasize 12-step principles, anger management techniques, and short-term therapeutic interventions, tailoring their approach to meet the unique needs of adult males. Both men and women can receive specialized support at this esteemed recovery facility.

Preferred Family Healthcare Inc

Preferred Family Healthcare Inc in Trenton, MO, delivers extensive addiction treatment for adults and adolescents. Their services encompass outpatient care, including regular outpatient programs, and round-the-clock residential options. Dedicated to personalized recovery, they offer distinct tracks for adult men, adult women, and individuals with a history of trauma. Employing evidence-based methods like 12-step facilitation, anger management, and brief interventions, the center effectively treats dual diagnoses of substance use and severe mental health conditions. Preferred Family Healthcare Inc fosters a nurturing atmosphere centered on meeting each person's specific recovery journey.

Prentice Place
Chicago, IL

Prentice Place, situated in Chicago, IL, provides targeted rehabilitation services for adult men dealing with substance abuse issues. The center features a range of programs, including intensive outpatient treatment, long-term residential stays, and outpatient services that integrate methodologies such as 12-step facilitation, anger management, and cognitive behavioral therapy. Prentice Place specifically serves adult men within the criminal justice system as well as those classified as forensic clients. By focusing on adult, senior, and young adult demographics, this facility is committed to offering personalized care and assistance to male clients striving to conquer addiction in a supportive and organized setting.

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Preferred Family Healthcare Inc in Macon, MO, provides outpatient treatment for substance use disorders aimed at adults and young adults who may also be facing significant mental health challenges or emotional issues. Their approach encompasses a range of methods, including 12-step support, anger management, and targeted brief interventions that cater to each individual’s specific circumstances. The center emphasizes personalized care and is open to clients of all genders. With a strong commitment to delivering high-quality care, this facility offers a nurturing atmosphere for individuals on their path to recovery from substance use issues. For those seeking tailored treatment in a caring environment, the services at Preferred Family Healthcare Inc may be the right choice.

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Preferred Family Healthcare Inc, located in Saint Louis, MO, provides a wide array of services for those struggling with addiction. This center focuses on detox services, treatment for substance use disorders, and tailored care for adults facing both substance use issues and significant mental health challenges, as well as for children experiencing serious emotional disturbances. The facility offers various options, including intensive outpatient treatment, outpatient programs, and treatment utilizing methadone, buprenorphine, or naltrexone. Employing methods such as 12-step programs, anger management, and brief interventions, the center serves a diverse clientele, including men, women, young adults, and others seeking recovery support. Those in need can expect compassionate care and individualized treatment plans aimed at fostering successful recovery journeys.

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Preferred Family Healthcare Inc, located in Saint Peters, MO, delivers a variety of substance use rehabilitation services for both adults and youths facing significant mental health challenges or emotional issues. This center offers intensive outpatient programs, standard outpatient care, and treatments involving methadone, buprenorphine, or naltrexone. The treatment plan includes methods such as 12-step facilitation, anger management, and brief interventions, designed to address the specific requirements of each patient. With dedicated programs for younger clients and services that accommodate individuals of all genders, this facility is committed to providing comprehensive support. Patients can anticipate high-quality, evidence-based care within a nurturing atmosphere aimed at fostering enduring recovery.

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Preferred Family Healthcare Inc in Springfield, MO delivers a full spectrum of addiction recovery services designed to address unique personal circumstances. Their offerings include structured intensive outpatient care, standard outpatient support, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Employing strategies such as 12-step engagement, emotional regulation techniques, and short-term counseling, the center champions a well-rounded path to sobriety. Tailored interventions are available for adult men, adult women, and young adults, accommodating both male and female individuals with gender-specific support. Preferred Family Healthcare Inc is devoted to providing high-caliber assistance to adults striving for freedom from addiction.

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Preferred Family Healthcare Inc in Canton, MO, provides extensive support for individuals of all ages struggling with substance use disorders, particularly when co-occurring with significant mental health conditions. Their treatment options include outpatient services such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Emphasizing personalized care, the center integrates approaches like 12-step program support, anger management techniques, and brief intervention strategies. Each client receives a unique treatment plan tailored to foster lasting recovery. The facility also offers gender-specific programming to cater to both male and female patients. Preferred Family Healthcare Inc is recognized for its dedication to providing a comprehensive and individualized path to recovery for everyone.

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Preferred Family Healthcare Inc, situated in Kahoka, MO, provides outpatient programs for adults and young adults battling addiction and co-occurring severe mental health conditions. Their services include standard outpatient care employing methods like 12-step support, anger management techniques, and brief intervention strategies. Catering to both men and women, the center prioritizes personalized treatment. The program's distinctive focus on tailoring care ensures that each patient receives a treatment plan uniquely developed for their recovery. This facility is recognized for its commitment to high-quality, specialized programs designed to meet the distinct requirements of every individual.

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Preferred Family Healthcare Inc. in Saint Louis, MO, delivers extensive support for individuals grappling with substance use disorders, including those with co-occurring severe mental health challenges. They offer various levels of care, such as intensive outpatient services, general outpatient programs, and specific medication-assisted treatment options including methadone, buprenorphine, or naltrexone. The facility employs evidence-based therapies like 12-step facilitation, anger management techniques, and brief intervention strategies. Their services are designed for adult men and women, as well as young adults, with programs adapted to the unique needs of different age demographics and genders, ensuring a personalized recovery journey. Preferred Family Healthcare Inc. is recognized for its commitment to effective care and a broad spectrum of treatment modalities, serving as a vital resource for individuals pursuing lasting sobriety.

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Preferred Family Healthcare Inc in Florissant, MO, provides extensive support for individuals and families struggling with addiction. They deliver a full spectrum of substance use treatment, addressing the needs of adults and young people grappling with dual diagnoses of substance use and mental health disorders. Services are available in various formats, including intensive outpatient and standard outpatient programs, alongside medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center employs individualized strategies like 12-step facilitation, anger management techniques, and brief intervention methods to optimize patient outcomes. Their specialized offerings for adolescents, adult men, and adult women demonstrate a commitment to meeting unique requirements. This center ensures equitable and effective care for all genders, guiding clients toward a successful recovery journey.

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Preferred Family Healthcare Inc, situated in Troy, MO, delivers targeted care for adults facing co-occurring mental health and substance use disorders, as well as children with significant emotional challenges. The facility offers a range of services, including intensive outpatient, general outpatient, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Their therapeutic approach incorporates 12-step facilitation, anger management, and brief intervention strategies. Serving a diverse clientele of all ages and genders, including young people, Preferred Family Healthcare Inc is recognized for its individualized adolescent programs and dedication to high-quality addiction treatment.

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Located in Alamogordo, NM, Presbyterian Medical Services provides outpatient services aimed at treating substance use disorders along with specialized support for those facing significant mental health challenges. The center utilizes proven methods such as anger management, brief intervention techniques, and cognitive behavioral therapy in its regular outpatient programs. Services are designed for adult men, women, and youth, including children and adolescents who have gone through traumatic experiences. Emphasizing personalized care, the facility is committed to delivering high-quality treatment tailored to the needs of each client. Whether addressing addiction issues or mental health problems, this center offers extensive support for both adults and young individuals.

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Prestera Center for MH Services Inc, situated in Huntington, WV, provides extensive rehabilitation programs for adult men facing challenges related to substance abuse and concurrent serious mental health conditions. The center features long-term residential options and around-the-clock support, alongside targeted therapies like 12-step programs and anger management sessions. It's designed to assist various groups, including active duty military members, adult males, and those who have suffered from intimate partner violence. Prioritizing personalized care and high-quality support, this facility fosters a secure and organized setting for adults and seniors pursuing recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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