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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Princeton Detox and Recovery Center

Princeton Detox and Recovery Center, located in Monmouth Junction, NJ, specializes in providing thorough detoxification and substance abuse treatment within a residential environment. The center ensures round-the-clock support and features targeted programs for both adult men and women, particularly those affected by intimate partner or domestic violence. It serves adults and young adults across genders, integrating various methodologies including 12-step support, anger management, and short intervention strategies. Committed to delivering high-quality care, Princeton Detox and Recovery Center is distinguished by its customized programs and dedicated assistance for individuals aiming to conquer their addiction challenges.

Principles Recovery Center
Fort Lauderdale, FL

Principles Recovery Center, situated in Fort Lauderdale, FL, delivers a comprehensive suite of scientifically validated therapies for addiction and co-occurring psychological conditions affecting adults and young individuals. Their program offerings include intensive outpatient, outpatient, and day treatment services, all delivered through tailored care models that incorporate strategies like 12-step facilitation, anger management techniques, and brief intervention. Distinctive programs are available for active military personnel, teenagers, and adult males, accommodating diverse age demographics and genders. Dedication to superior care is a cornerstone, with the center emphasizing a whole-person approach to healing and customized treatment regimens designed to guide individuals toward lasting recovery.

ProMedica Monroe Regional Hospital

ProMedica Monroe Regional Hospital, located in Monroe, MI, provides extensive outpatient care for individuals of all ages experiencing substance use disorders, particularly those also managing significant mental health conditions. Employing techniques such as motivational interviewing, cognitive behavioral therapy, and brief intervention, the hospital delivers customized treatment plans designed for each patient. The facility is dedicated to offering high-quality, individualized support for both male and female clients pursuing recovery. By offering scientifically-backed therapies within a nurturing setting, ProMedica Monroe Regional Hospital stands as a crucial provider for integrated addiction and mental wellness services.

Prestera Health Services

Prestera Health Services, situated in Hurricane, WV, provides outpatient treatment for substance use disorders affecting both adults and children grappling with significant emotional challenges. The facility focuses on addressing both substance use and concurrent mental health conditions. By employing methods like 12-step programming, cognitive behavioral therapy, and the Matrix Model, the center ensures that care is customized to meet individual requirements. With tailored programs for clients involved in the criminal justice system, Prestera Health Services accommodates adults and seniors of various backgrounds. For individuals in search of a nurturing atmosphere for addiction recovery, this center is an excellent option for rehabilitation and support.

Pride Institute
Eden Prairie, MN

The Pride Institute, situated in Eden Prairie, MN, delivers thorough addiction recovery services for adults and young adults contending with significant co-occurring mental health conditions. They offer flexible program lengths including extended, shorter, and round-the-clock residential care, ensuring personalized support through methodologies like 12-step integration, brief counseling, and cognitive behavioral techniques. The center features distinct programs for adult men and women, as well as those impacted by intimate partner or domestic abuse. Emphasizing excellence and customized treatment paths, the Pride Institute is committed to guiding individuals toward lasting wellness.

Professional Counseling Center PC

Situated in Port Huron, MI, Professional Counseling Center PC provides outpatient treatment for substance use disorders for both adults and children/adolescents facing concurrent mental health challenges. The center is known for its tailored approach, emphasizing personalized care that incorporates 12-step programs, anger management strategies, and brief therapeutic interventions. Catering to both male and female clientele, they offer consistent outpatient services designed to address the complexities of substance-related issues alongside significant emotional difficulties. For those in pursuit of specialized addiction support in Port Huron, Professional Counseling Center PC is a compelling option to explore.

Prisma Health
Columbia, SC

Prisma Health in Columbia, SC provides extensive support for individuals, both adults and young adults, facing challenges with substance abuse. Their services encompass detox and focused outpatient care, employing proven methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing recurrence. Prisma Health also features distinct programs for those with accompanying mental health conditions, ensuring customized treatment plans to meet unique requirements. Available options include outpatient services and day treatment, serving both men and women on their path to recovery in a nurturing setting. Discover individualized attention and successful interventions at this establishment committed to fostering long-term abstinence.

Process of Changes Inc
Catonsville, MD

Process of Changes Inc. in Catonsville, MD, provides a complete spectrum of addiction recovery support for adults and older adults, welcoming individuals of any gender. Their offerings encompass drug and alcohol detoxification, comprehensive substance abuse therapy, supportive transitional living arrangements, and robust outpatient care. Employing methodologies like 12-step program integration, emotional regulation training, and cognitive restructuring, this establishment delivers tailored interventions to meet the distinct requirements of every person. Emphasizing excellence and individualized care, Process of Changes Inc. is recognized for its dedication to fostering enduring sobriety. Clients pursuing either intensive outpatient or partial hospitalization services will find a place of empathetic guidance and scientifically-backed treatment at this distinguished facility.

Process Recovery Center

Process Recovery Center, situated in Nashua, NH, delivers various treatment options for substance use disorders aimed at both adults and young adults. This facility specializes in intensive outpatient services, outpatient day programs, and partial hospitalization, emphasizing 12-step support, anger management, and brief intervention methods. Tailored programs are available for adult men, adult women, and LGBTQ clients. The center also features transitional housing to create a nurturing atmosphere for individuals pursuing recovery. Gender-specific treatment ensures customized support for both men and women. Process Recovery Center is committed to offering exceptional and thorough care to assist individuals in their path to sobriety.

Professional Care Services Inc

Professional Care Services Inc, located in Covington, TN, provides comprehensive outpatient care for individuals of all ages struggling with addiction and co-occurring mental health conditions. Their specialized programs are designed for those with dual diagnoses, utilizing therapeutic interventions such as anger management, cognitive behavioral therapy, and brief intervention. The center caters to both male and female clients, offering not only general outpatient services but also medication-assisted treatment with methadone, buprenorphine, or naltrexone. Professional Care Services Inc is dedicated to offering effective support and high-quality treatment for those on their journey to recovery.

ProTech Recovery
Seymour, IN

ProTech Recovery, located in Seymour, IN, provides an extensive array of outpatient services designed for individuals aiming to overcome substance use disorders and related mental health issues. This center features targeted treatment programs for adults facing severe mental health challenges, children experiencing emotional difficulties, and those who have lived through intimate partner violence. Emphasizing techniques such as 12-step programs, anger management, and short-term therapeutic interventions, ProTech Recovery customizes its strategies to cater to the specific requirements of each individual. The center serves adult men and women alike, offering outpatient detox services alongside medication-assisted treatments that include options like methadone, buprenorphine, or naltrexone. Clients can anticipate empathetic support and scientifically backed methodologies to aid them in achieving sustainable recovery.

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Prestera Center for MH Services Inc, situated in Point Pleasant, WV, is dedicated to offering targeted outpatient services for individuals dealing with substance abuse and simultaneous mental health issues, servicing both adults and children. The center employs a variety of evidence-backed methodologies, such as 12-step programs, anger management techniques, and cognitive behavioral therapy. It features programs tailored specifically to the needs of males and females, addressing the requirements of individuals facing multifaceted treatment challenges. By focusing on those with co-occurring disorders, the center guarantees holistic support for clients across all age ranges, making it an essential establishment for individuals in search of effective addiction and mental health services in the region.

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Prestera Center for MH Services Inc, located in Huntington, WV, specializes in extensive substance abuse treatment for both adults and young adults facing significant mental health challenges or emotional issues. The center features intensive outpatient and standard outpatient programs, offering treatments like methadone/buprenorphine and naltrexone. Dedicated to personalized care, this facility employs evidence-based methods such as cognitive behavioral therapy, anger management, and motivational incentives/contingency management. Catering to a diverse clientele of men and women, the center is distinguished by its individualized treatment strategies and dedication to high-quality service.

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Situated in Wayne, WV, the Prestera Center for MH Services Inc delivers extensive outpatient rehabilitation options for those facing challenges related to substance use and concurrent mental health issues. This center features targeted treatment initiatives aimed at adults dealing with serious mental health conditions, as well as children experiencing emotional challenges. Employing evidence-based strategies such as 12-step programs, anger management techniques, and cognitive behavioral therapy, the facility supports clients of all genders. With an emphasis on superior care, the Prestera Center also includes outpatient services for methadone/buprenorphine or naltrexone, serving as a crucial support system for individuals pursuing recovery. Moreover, the center offers specialized programs designed for clients within the criminal justice system, providing customized assistance for those in specific situations.

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Prestera Center for MH Services Inc, located in Huntington, WV, delivers complete addiction treatment within a supportive setting. The facility offers residential options of varying durations, including 24-hour care, all customized to individual requirements. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and brief intervention, they serve adult women who have faced intimate partner violence, domestic violence, and sexual abuse. Their specialized programs for adults, seniors, and young adults, with a particular focus on female patients, guarantee high-quality care and a nurturing atmosphere for individuals pursuing recovery from substance use disorders.

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Prestera Health Services, situated in Danville, WV, delivers extensive outpatient care designed for individuals facing substance use issues as well as co-occurring mental health disorders, applicable to both adults and children. This facility specializes in various therapeutic interventions, including anger management, cognitive behavioral therapy, and motivational interviewing, ensuring a personalized treatment experience. Catering to a diverse clientele of adults and seniors across all genders, Prestera Health Services offers options such as regular outpatient treatments and medication-assisted therapies with methadone, buprenorphine, or naltrexone. Notably, the center prioritizes customized programs and evidence-based methods, making it a top choice for those seeking effective recovery solutions.

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Woodbridge, VA

Prince William County, located in Woodbridge, VA, specializes in outpatient treatment for substance use disorders, as well as addressing concurrent mental health issues in adults and emotional challenges in children. The center implements various treatment modalities, including outpatient options for methadone, buprenorphine, and naltrexone. Emphasizing brief interventions, cognitive behavioral therapy, and the Matrix Model, this facility serves teenagers, adult men, and women alike. It caters to both adult and senior clients, offering personalized treatment plans for individuals. The diverse strategies and specialized programs at Prince William County demonstrate its dedication to delivering thorough and effective rehabilitation services.

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The rehabilitation facility situated in Manassas, VA, known as the Prince William County rehabilitation center, delivers thorough substance abuse recovery programs for both young people and adults facing concurrent mental health conditions. This establishment features outpatient options such as methadone and buprenorphine therapy, alongside standard outpatient support. The center's expertise lies in brief interventions, cognitive behavioral therapy, and the Matrix Model. It accommodates diverse age groups with dedicated treatment plans for teenagers, adult men, and women. The Prince William County center is committed to providing excellent, personalized care for individuals of any gender, including older adults, who are navigating addiction and mental health recovery.

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Pro Med Substance Abuse Prog LLC, located in Hamtramck, MI, delivers focused treatment for adults and young adults grappling with substance use and concurrent mental health issues. The center offers a range of programs including intensive outpatient, outpatient, and partial hospitalization, utilizing proven methods such as 12-step facilitation and anger management. Catering to the needs of active military members as well as adult men and women, the facility fosters an inclusive atmosphere for all genders. Prioritizing personalized treatment strategies and high-quality care, those in need of thorough and effective addiction recovery support can turn to Pro Med Substance Abuse Prog LLC for specialized assistance.

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Based in Delano, MN, the Professional Counseling Center provides specialized care for substance use and transitional housing within a nurturing atmosphere. This center focuses on treating adults with dual diagnoses of substance use and significant mental health challenges, as well as addressing emotional issues in children. Offered services encompass intensive outpatient and day treatment programs, employing techniques such as 12-step methodologies and anger management. The center serves adults and young adults of various backgrounds, ensuring tailored support for those with co-occurring conditions. Emphasizing personalized and high-quality care, the Professional Counseling Center stands as a symbol of hope for individuals in need of thorough rehabilitation solutions.

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The Professional Counseling Center in Minneapolis, MN, delivers comprehensive support for those overcoming substance use challenges and requiring interim housing. They provide structured intensive outpatient and day treatment programs, incorporating proven methods like 12-step facilitation and anger management techniques. This center serves adults and young adults, with dedicated programs designed for individuals facing dual diagnoses of mental health and substance use conditions. Their commitment to high-quality, personalized care empowers individuals on their path to lasting recovery. Both men and women are welcome to access the full spectrum of treatment services available.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)