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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Project Renewal
New York, NY

Project Renewal, situated in New York, NY, provides extensive support for those overcoming substance use challenges. Their offerings include robust intensive outpatient care, general outpatient services, and specialized medication-assisted treatment using methadone, buprenorphine, or naltrexone. Focusing on vital areas like anger control, early intervention, and motivational strategies, the center welcomes adult men, adult women, and individuals impacted by trauma. Project Renewal extends its reach to adults, seniors, and young adults across all gender identities, ensuring tailored recovery journeys. The center's dedication to exceptional care is evident in its targeted programs and varied therapeutic methods, designed to support each person's path to sobriety.

Promises Behavioral Health

Promises Behavioral Health located in Dickson, TN, delivers an extensive array of addiction recovery services aimed at both adults and young adults. The facility features detox programs, treatments for substance use, and targeted support for those dealing with dual diagnoses of substance use and severe mental health disorders. Treatment options range from intensive outpatient care to long-term residential stays and outpatient services, allowing clients to receive customized support. Promises Behavioral Health employs evidence-based methods, including 12-step programs, anger management techniques, and brief interventions, fostering a well-rounded treatment environment. Specialized programs are available for adult men, adult women, and those affected by intimate partner violence, reflecting the center's dedication to personalized care. Focusing on high-quality and individualized treatment, Promises Behavioral Health creates a nurturing space for individuals on their recovery journey.

Promises Five Palms
Ormond Beach, FL

Nestled in Ormond Beach, Florida, Promises Five Palms delivers thorough detox services and addiction recovery treatment. Their offerings include inpatient detox, continuous residential support around the clock, and shorter residential stays designed for adults and young adults regardless of gender. Employing methods like anger management, cognitive behavioral therapy, and brief intervention, the facility serves individuals facing dual diagnoses of mental health and substance use challenges, as well as those with histories of trauma. Promises Five Palms is dedicated to offering excellent care and assistance to people striving for freedom from addiction.

Promont Wellness
Southampton, PA

Promont Wellness, located in Southampton, PA, provides extensive treatment options for substance use to both adults and young adults, featuring intensive outpatient and outpatient day programs. The center has a strong emphasis on anger management, cognitive behavioral therapy, and motivational techniques. It also offers distinct programs designed for individuals with a history of trauma and those facing co-occurring disorders. Promont Wellness ensures personalized care for everyone, regardless of gender, fostering a welcoming and supportive atmosphere. With a commitment to evidence-based practices and customized treatment plans, this center is focused on providing exceptional care to assist clients in achieving sustainable recovery.

Prosperity Haven
Chardon, OH

Situated in Chardon, OH, Prosperity Haven delivers targeted treatment programs for adult males struggling with substance use issues. The center offers hospital-based inpatient care, round-the-clock medical supervision, and intensive outpatient services. Emphasizing methods such as 12-step support, anger management, and short-term intervention techniques, Prosperity Haven serves clients affected by domestic violence, intimate partner violence, and sexual abuse. Catering to adults, including seniors and younger adults, the facility provides individualized support for men on their path to recovery. Prosperity Haven is distinguished by its all-encompassing programs and dedication to providing effective rehabilitation solutions.

Project Free
Trenton, NJ

Nestled in Trenton, NJ, Project Free delivers thorough addiction recovery solutions for both adults and younger individuals. This center features intensive outpatient programs, outpatient detoxification, and general outpatient services designed for those facing challenges with substance abuse and co-occurring mental health issues. Employing proven methods like cognitive behavioral therapy and anger management, Project Free is particularly adept at supporting clients with histories of trauma and those managing dual diagnoses. Their specialized programs for adult women, emphasizing high-quality care and personalized treatment strategies, establish Project Free as a premier destination for individuals seeking expert and impactful rehabilitation.

Project Hospitality Inc
Staten Island, NY

Situated in Staten Island, NY, Project Hospitality Inc delivers a wide range of services for those struggling with substance use disorders, catering to adults and young adults alike. The facility focuses on individuals facing both substance use challenges and severe mental health issues or emotional disturbances in younger populations. Treatment options available here include intensive outpatient care, outpatient services, and medication-assisted treatments like methadone, buprenorphine, or naltrexone. The center employs a variety of therapeutic methods including anger management, brief interventions, and cognitive behavioral therapy tailored to individual needs. Project Hospitality Inc also has specialized programs designed for adult men, women, and those who have encountered intimate partner or domestic violence, emphasizing quality support for all clients as they navigate their journey toward recovery.

Progress Valley 2
Minneapolis, MN

Progress Valley 2, located in Minneapolis, MN, specializes in holistic rehabilitation for both adults and young adults dealing with substance use issues along with concurrent mental health disorders. The center offers a range of treatment options, such as intensive outpatient services, long-term residential placements, and outpatient care. Employing proven methods like 12-step programming, cognitive behavioral therapy, and contingency management, the facility customizes its approach to meet the specific needs of each individual. Specific programs are also available for adult women and those with co-occurring conditions. With an emphasis on high-quality, personalized care, Progress Valley 2 provides supportive rehabilitation services for both men and women.

Project ADAM
Winder, GA

Situated in Winder, GA, Project ADAM provides a wide array of services for adults and young adults dealing with substance use issues. The center specializes in addressing the needs of those with both substance use disorders and significant mental health challenges. Offering various treatment options such as inpatient hospital care, intensive outpatient programs, and extended residential treatment, Project ADAM adapts its services to cater to individual requirements. The facility emphasizes strategies like 12-step engagement, anger management, and short intervention techniques to ensure customized support. There are specialized programs designed for teenagers, adult men, and adult women. Project ADAM is committed to offering high-quality, gender-sensitive treatment to assist individuals on their recovery journey.

Project Reality
Salt Lake City, UT

Project Reality, situated in Salt Lake City, UT, provides extensive outpatient care for those facing addiction and simultaneous mental health challenges. They focus on safe withdrawal, addiction recovery, and managing significant emotional distress in youth, as well as adult mental health conditions. Services include outpatient detox, medication-assisted treatment with methadone or buprenorphine, and various therapies like anger management and CBT. They offer specialized programs for military personnel, teenagers, and adult men, serving both children and adults of all genders. Expect individualized treatment and high-standard support at this premier recovery facility.

Project Reality
Salt Lake City, UT

Nestled in Salt Lake City, UT, Project Reality is dedicated to providing thorough recovery programs for individuals of all ages facing addiction and psychological challenges. The center offers services such as non-residential detox, addiction therapy, and targeted support for dual diagnoses within a nurturing atmosphere. Emphasizing cognitive behavioral techniques, emotional regulation strategies, and short-term counseling, Project Reality customizes its approach to suit each person's unique requirements. Distinctive programs are available for active military members, teenagers, and adult men. Serving both genders, the facility is committed to delivering excellent care to foster enduring well-being.

Project Turnabout
Granite Falls, MN

Situated in Granite Falls, MN, Project Turnabout delivers extensive rehabilitation services for those facing addiction challenges. The center offers detox services, treatment for substance use disorders, and specialized support for individuals with co-occurring conditions, including serious mental health issues in adults and significant emotional disturbances in children. Project Turnabout features various programs such as intensive outpatient, long-term residential, and outpatient care, serving both adults and children/adolescents of all genders. Their customized treatment strategies encompass 12-step methods, anger management, and brief interventions. Additionally, the facility provides targeted programs for adolescents, men, and women to ensure individualized attention for everyone. Project Turnabout is committed to offering high-quality and impactful treatment options for individuals pursuing recovery.

Project Turnabout
Marshall, MN

Project Turnabout, situated in Marshall, MN, provides a full spectrum of substance abuse recovery options designed for those requiring assistance. The facility features intensive outpatient care, extended residential stays, and outpatient services employing established techniques like 12-step integration, cognitive behavioral therapy, and short-term counseling. Concentrating on adult men, individuals affected by intimate partner violence, and survivors of domestic abuse, Project Turnabout extends specialized care to adults and young adults regardless of gender. Its commitment to high-quality support and varied therapeutic approaches establishes it as a significant center for successful recovery.

Psychiatric Care Center

The Redding, CA based Psychiatric Care Center provides all-encompassing addiction treatment and expert care for adults with dual diagnoses of substance use and severe mental health conditions, or children with serious emotional disturbances. They offer intensive outpatient and regular outpatient services, featuring medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Utilizing proven therapeutic methods including anger management, cognitive behavioral therapy, and motivational interviewing, this center crafts personalized programs for teens, adult men, and adult women. Open to all genders in adult and child/adolescent populations, the center is committed to delivering top-tier, impactful rehabilitation to foster sustained recovery.

Promesa Inc
Buffalo, NY

Promesa Inc, located in Buffalo, NY, delivers extensive addiction recovery services via various program levels, including outpatient, medication-assisted treatment (methadone/buprenorphine or naltrexone), and standard outpatient options. Employing therapeutic modalities such as 12-step facilitation, anger management, and brief interventions, the center addresses the needs of active military members, young people, and adult males. Serving a broad age range from children to adults, Promesa Inc also accommodates both male and female patients. The center's strength lies in its customized treatment plans, guaranteeing high-quality support for those pursuing freedom from addiction. For individuals in search of impactful, individualized recovery assistance, this establishment is committed to fostering your path to wellness.

Providence Alaska Medical Center

Providence Alaska Medical Center, located in Anchorage, AK, provides a wide array of addiction recovery services for both adults and youth. The facility is known for its expertise in detoxification, treatment for substance use disorders, and addressing co-occurring mental health conditions for adults as well as emotional challenges in younger patients. Treatment modalities available include intensive outpatient care, regular outpatient services, and outpatient detox programs. The center employs various therapeutic strategies, such as 12-step programs, brief interventions, and cognitive behavioral therapy, to ensure personalized treatment. Special programs are designed to meet the needs of adolescents, adult men, and women, emphasizing customized care plans. Committed to delivering high-quality support, Providence Alaska Medical Center plays a vital role in assisting individuals as they navigate their recovery process.

Providence Little Company of

Providence Little Company of in San Pedro, CA, extends a full spectrum of care for individuals grappling with addiction. Their services encompass inpatient hospital detoxification and therapeutic interventions for substance use challenges, alongside support for concurrent mental health issues. The treatment framework integrates methods like 12-step support, emotional regulation techniques, and short-term counseling to meet each person's distinct situation. Through dedicated tracks for active military personnel, adult men, and women, the center serves a broad range of needs. Clients will receive expert care designed to their specific circumstances, fostering a nurturing setting for healing and growth.

Promesa Inc
Bronx, NY

Promesa Inc, situated in Bronx, NY, delivers outpatient services for individuals of all ages struggling with substance use. Their expertise lies in anger management, brief intervention techniques, and cognitive behavioral therapy, enabling them to offer personalized support to those affected by intimate partner or domestic violence. Promesa Inc develops distinct programs for adult men and women, crafting treatment strategies that are precisely suited to each person's specific circumstances and requirements. This dedication to high-quality, thorough care solidifies Promesa Inc's reputation as a reliable provider of successful recovery programs within the Bronx community.

Providence Center
Cranston, RI

Situated in Cranston, RI, Providence Center delivers targeted treatment for substance use disorders, catering to adult men, seniors, and young adults. The center features both long-term and short-term residential options, providing a well-rounded methodology for recovery. By incorporating cognitive behavioral therapy, strategies for preventing relapse, and counseling for substance use disorders, the facility customizes its offerings to address the unique needs of each individual. Focused on a personalized care model, Providence Center ensures that every client benefits from high-quality, tailored support. Its dedication to fostering enduring sobriety through proven practices and a nurturing atmosphere distinguishes the center in the field of rehabilitation.

Providence Center

Providence Center, located in Wyoming, RI, provides tailored substance abuse recovery services for adult women, seniors, and young adults. They offer a range of program durations, including extended, brief, and round-the-clock residential care. The facility emphasizes cognitive behavioral techniques, strategies for avoiding relapse, and professional counseling for addiction. Each client receives a personalized treatment strategy designed to address their specific requirements, guaranteeing thorough assistance and backing throughout their journey to sobriety. Providence Center is recognized for its dedication to high-quality treatment and specialized offerings, positioning it as a leading option for women looking for effective and customized addiction care within a secure and encouraging setting.

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Dunkirk, NY

Promesa Inc, located in Dunkirk, NY, delivers complete care for substance abuse and co-occurring mental health conditions, serving adults and youth. They offer outpatient options, including methadone and buprenorphine services. Promesa Inc employs proven methods like cognitive behavioral therapy and anger management. The facility has dedicated programs for active military personnel, teenagers, and adult men, accommodating a wide range of individuals. They provide care for both male and female clients, ensuring individualized support. Promesa Inc's commitment to high standards and customized recovery plans makes it an important support system for those aiming to address addiction and mental health concerns.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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