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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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R and R Recovery
Huntington Beach, CA

R and R Recovery in Huntington Beach, CA, delivers a complete spectrum of care for individuals struggling with addiction. They offer intensive outpatient, standard outpatient, and partial hospitalization programs. Their therapeutic methods include anger management, cognitive behavioral therapy, and the Matrix Model, addressing the needs of those with co-occurring mental health and substance use issues, as well as individuals with histories of sexual abuse or trauma. Tailored programs for men and women are available, reflecting R and R Recovery's commitment to personalized, high-quality support for sustained sobriety.

RAM Recovery LLC
Waldorf, MD

RAM Recovery LLC, located in Waldorf, MD, delivers a wide range of substance abuse treatment options, including intensive outpatient programs, outpatient services, and medication-assisted therapies such as methadone/buprenorphine or naltrexone. The center employs techniques like 12-step facilitation, anger management, and cognitive behavioral therapy, aiming to support adult men and women, including those who have suffered from intimate partner or domestic violence. With a specialization in care for adults and young adults, RAM Recovery LLC offers personalized treatment plans tailored to the needs of both male and female clients. Committed to high-quality care and evidence-based practices, it stands out as a reliable option for those seeking rehabilitation in the Waldorf community.

RECO Intensive
Delray Beach, FL

Situated in Delray Beach, Florida, RECO Intensive delivers a wide range of substance use rehabilitation services for both adults and young adults. The center features intensive outpatient programs, standard outpatient services, and day treatment options, also known as partial hospitalization. The treatment methods applied include 12-step strategies, anger management, and brief intervention techniques, ensuring that each program is customized to fit the unique needs of clients. RECO Intensive is particularly adept at accommodating adult men and women, including those who have faced intimate partner or domestic violence. Committed to providing high-quality care and individualized treatment approaches, this center aims to aid individuals in their recovery journey.

ROAD to a Better Life
Somersworth, NH

"ROAD to a Better Life" located in Somersworth, NH, provides outpatient services for adults and young adults dealing with substance use issues. This center focuses on preventing relapse and delivers personalized care aimed at achieving high standards. It offers various outpatient options including methadone/buprenorphine or naltrexone therapies, regular outpatient services, and telehealth sessions. Each program is customized to meet the specific needs of clients, whether they are male or female, who are on their path to recovery. If you’re in search of a detailed outpatient program that emphasizes individual care and relapse prevention strategies, "ROAD to a Better Life" may be an ideal fit for you.

RHA Health Services
Asheville, NC

Nestled in Asheville, NC, RHA Health Services stands as a beacon of comprehensive rehabilitation, dedicated to assisting adults and seniors navigating the complexities of substance use disorders and co-occurring mental health challenges. Their offerings encompass robust intensive outpatient treatment, flexible outpatient services, and targeted medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing proven methodologies like cognitive behavioral therapy and anger management techniques, the center prioritizes exceptional care crafted around each person's unique journey. RHA Health Services welcomes both men and women, featuring distinct programs tailored for adult men, adult women, and individuals impacted by intimate partner or domestic violence. For those in search of specialized, empathetic support within a nurturing setting, this center provides a well-rounded path toward lasting recovery.

ROAD to a Better Life

"ROAD to a Better Life" located in Merrimack, NH, delivers extensive treatment options for substance use disorders aimed at both adults and young adults. This center offers outpatient services that include methadone, buprenorphine, or naltrexone therapies, alongside strategies for relapse prevention and telehealth services. Committed to personalized care, "ROAD to a Better Life" serves both male and female clients, ensuring that each treatment plan is customized to meet individual needs. For those in search of compassionate and effective addiction recovery solutions, this facility is devoted to helping you pave your path to a brighter and healthier future.

RUHS/Behavioral Health
Palm Springs, CA

RUHS/Behavioral Health, located in Palm Springs, CA, provides an extensive array of treatment options for individuals dealing with substance abuse and concurrent mental health disorders. The center features intensive outpatient services, outpatient day care, and partial hospitalization programs, all employing proven methods like cognitive behavioral therapy and the Matrix Model. Specialized programs are designed for active-duty military members, teenagers, and adult males. With an emphasis on adults and young adults of all genders, this facility is dedicated to offering effective care that aids individuals on their path to recovery.

ROAD to a Better Life

Situated in Concord, NH, "ROAD to a Better Life" is a dedicated rehabilitation facility that specializes in outpatient treatment for substance use disorders. This center provides various treatment options, including outpatient services for methadone, buprenorphine, or naltrexone, regular outpatient therapy, as well as telemedicine and telehealth sessions. Emphasizing relapse prevention and tailored counseling for substance use issues, the center ensures customized care plans for both adults and adolescents. Committed to delivering high-quality support, "ROAD to a Better Life" welcomes male and female clients who are looking for an individualized journey towards recovery.

RHA Health Services
Lumberton, NC

RHA Health Services in Lumberton, NC, specializes in comprehensive care for adults facing substance use disorders and co-occurring mental health conditions, alongside children with significant emotional challenges. They offer a spectrum of services, including intensive outpatient, outpatient, and day treatment, employing evidence-based therapeutic modalities like anger management, cognitive behavioral therapy, and the Matrix Model. The center features individualized treatment plans designed for adolescents, adult men, and adult women. RHA Health Services welcomes individuals of all genders across both adult and youth populations, delivering high-quality, supportive rehabilitation.

REACH Program
New York, NY

Nestled in New York, NY, the REACH Program provides a full spectrum of care for individuals struggling with substance use disorders, catering to adults and young adults. This center is particularly adept at addressing dual diagnoses, treating co-occurring substance use issues with severe mental health conditions in adults and significant emotional challenges in children. Their treatment offerings include intensive outpatient, outpatient, and standard outpatient services, delivered through personalized strategies like anger management, brief intervention, and cognitive behavioral therapy. Dedicated programs are available for active duty military, adult men, and adult women. The REACH Program is committed to delivering high-quality, gender-inclusive care, fostering personalized treatment plans for sustained recovery.

RHA Health Services Inc

RHA Health Services Inc, situated in Bakersville, NC, provides thorough substance use care for adults and youth experiencing dual mental health challenges. Their offerings encompass intensive outpatient and standard outpatient programs, featuring methadone and buprenorphine options. The facility is equipped with specific tracks for those impacted by domestic violence, sexual assault, and trauma, fostering a secure environment for recovery. Employing proven methods like 12-step facilitation and anger management, they serve both male and female individuals. RHA Health Services Inc is dedicated to delivering high-quality support for those on the path to overcoming addiction and trauma.

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Situated in Dayville, CT, the Quinebaug Day Treatment Program provides a full spectrum of care for those pursuing recovery from addiction, mental health challenges, and the complexities of co-occurring disorders. Its offerings encompass intensive outpatient and partial hospitalization programs, designed to serve both adolescents and adults. The center features tailored interventions for young adults and individuals facing dual diagnoses. Employing strategies like 12-step integration and anger management techniques, Quinebaug Day Treatment Program is dedicated to offering exceptional support to all its male and female patients. This facility represents a significant resource for effective recovery and well-being.

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Radiant Health North, situated in Marion, Indiana, delivers extensive rehabilitation programs tailored for both adults and children struggling with substance use challenges and accompanying mental health issues. The center offers inpatient detoxification services alongside various treatment options, specifically designed for individuals who have experienced trauma. Their therapeutic strategies encompass 12-step support, anger management techniques, and time-limited interventions. Catering to clients of all genders, Radiant Health North emphasizes personalized treatment plans. With its commitment to high-quality care and a comprehensive approach to healing, this center stands as a source of inspiration for those committed to recovery and embarking on a new chapter of vibrant health.

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Radiant Health South, situated in Marion, IN, provides excellent outpatient rehabilitation for those recovering from substance abuse and co-occurring mental health issues. This center offers tailored programs for adults with severe mental health conditions and children with emotional challenges, employing proven methods like 12-step facilitation, anger control, and concise interventions. A distinguishing feature of the center is its emphasis on trauma-informed care, serving male and female clients across all age groups. Whether it's outpatient methadone/buprenorphine treatment or standard outpatient care, Radiant Health South ensures thorough and caring support for everyone aiming for sustained recovery.

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Situated in Ithaca, NY, the REACH Project Inc provides outpatient treatment for adults dealing with substance use issues, specifically catering to those who also have significant mental health challenges. This center offers a range of specialized treatments, including cognitive behavioral therapy, anger management, and brief intervention strategies. Customized programs are available for active military members, as well as for adult men and women. With its emphasis on serving both adult and young adult populations, this facility is noted for its outpatient treatment options involving methadone, buprenorphine, or naltrexone. The REACH Project Inc is committed to delivering excellent care for individuals in need of extensive rehabilitation support.

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Las Animas, CO

Located in Las Animas, CO, RESADA Outpatient provides outpatient substance abuse treatment options designed to meet diverse needs. Their programs emphasize approaches such as 12-step support, brief intervention techniques, and cognitive behavioral therapy. This facility accommodates active duty military members as well as adolescents and adult males. RESADA Outpatient is dedicated to serving individuals of all ages and genders, ensuring that treatment plans are personalized. With a strong focus on high-quality care and a range of treatment methodologies, RESADA Outpatient stands as a vital asset for those pursuing effective addiction recovery solutions in the Las Animas community.

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Nestled in Marion, NC, RHA Behavioral Health Services delivers thorough care for individuals grappling with substance use disorders and co-occurring mental health challenges. They also address serious emotional disturbances in younger individuals. The facility offers various levels of care, including intensive outpatient and outpatient programs, with medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Specific programs are available for adolescents, survivors of intimate partner violence, domestic abuse, and sexual assault. Utilizing personalized therapeutic methods such as 12-step facilitation, anger management techniques, and brief intervention strategies, RHA Behavioral Health Services supports both men and women across all age demographics. Select RHA Behavioral Health Services for skilled guidance and assistance throughout your journey to wellness.

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Whiteville, NC

Situated in Whiteville, NC, RHA Health Services delivers extensive treatment for substance use disorders among adults and young adults who also face significant mental health challenges or emotional issues. The center features a variety of programs, including intensive outpatient services, outpatient day programs, and partial hospitalization options. By employing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, RHA Health Services serves both men and women, as well as those who have dealt with intimate partner violence. With dedicated programs designed for various age groups and genders, the center is committed to providing customized care and support to all individuals on their path to recovery.

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Bladenboro, NC

Situated in Bladenboro, NC, RHA Health Services provides a wide range of treatment options for substance use disorders and specialized support for individuals dealing with co-occurring mental health issues. The facility offers intensive outpatient programs, outpatient day treatment, and partial hospitalization settings specifically designed for both adults and young adults. Emphasizing methods such as 12-step facilitation, cognitive behavioral therapy, and motivational incentives, RHA Health Services delivers tailored care to meet the unique needs of each person. The center also features specific programs catering to adult men, adult women, and those affected by domestic violence. Its gender-sensitive approach and dedication to delivering high-quality care position it as a vital asset for individuals in search of effective rehabilitation solutions.

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East Machias, ME

Situated in East Machias, ME, RMCL/HealthWays specializes in outpatient care for adults dealing with substance use issues alongside serious mental health disorders and offers support for children facing emotional challenges. The center offers a variety of services such as outpatient treatment with methadone, buprenorphine, or naltrexone, as well as anger management sessions, brief interventions, and cognitive behavioral therapy. RMCL/HealthWays designs specific programs for active duty military personnel, adolescents, and adult males, ensuring that it meets the needs of both adults and seniors across all genders. The facility is committed to providing top-notch care and personalized treatment strategies to foster recovery and well-being for every client.

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Staten Island, NY

The RUMC Silberstein Clinic, situated in Staten Island, New York, specializes in offering extensive treatment for substance use disorders for both adults and young adults who also experience mental health issues. This center delivers outpatient care, which includes options like methadone, buprenorphine, or naltrexone treatment. The program employs a variety of therapeutic techniques encompassing anger management, brief interventions, and cognitive behavioral therapy to provide comprehensive support. There are specialized programs designed for adult men, adult women, and individuals with concurrent mental health and substance use challenges. Committed to delivering personalized care, this clinic aids clients of all genders in their paths to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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