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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Rainbow Hill Recovery
Los Angeles, CA

Rainbow Hill Recovery, located in Los Angeles, CA, specializes in addressing substance abuse and co-occurring mental health issues for both adults and children. The center offers a variety of outpatient and day treatment programs, incorporating 12-step support, anger management, and short-term intervention strategies. They have distinctive programs designed for active duty military members, as well as tailored services for adult men and women. By providing high-quality care within a nurturing setting, Rainbow Hill Recovery effectively supports adults and young adults of all genders. Whether individuals are looking for intensive outpatient services or partial hospitalization, they receive customized care to facilitate their recovery process.

Rainbows End Recovery Center LLC

Rainbows End Recovery Center LLC in Challis, ID, provides comprehensive treatment for addiction and co-occurring mental health issues. They offer various levels of care, including intensive outpatient, long-term residential, and standard outpatient programs. Their therapeutic interventions incorporate proven methods like 12-step facilitation, anger management, and cognitive behavioral therapy. The center has specialized programs designed for adult men and women, as well as survivors of intimate partner violence or domestic abuse. Serving adults and young adults across the gender spectrum, Rainbows End Recovery Center LLC is dedicated to supporting individuals on their journey to recovery.

Raleigh House of Hope

Situated in Watkins, CO, the Raleigh House of Hope delivers an extensive array of addiction recovery services for both adults and young adults. The center features inpatient detox programs and provides round-the-clock medical care. Emphasizing 12-step methodologies, anger management strategies, and brief intervention tactics, this facility serves adult men and women, including individuals who have faced sexual trauma. With options for transitional living and halfway housing, the Raleigh House of Hope prioritizes personalized treatment for all clients. Committed to high standards and customized recovery plans, this center fosters a nurturing atmosphere for individuals aiming to overcome substance use challenges.

Ralph H Johnson VA Medical Center

The Ralph H Johnson VA Medical Center, located in Charleston, SC, provides an extensive array of rehabilitation services tailored for adults and seniors facing challenges related to substance abuse and concurrent mental health disorders. Their offerings encompass inpatient detoxification within a hospital setting, intensive outpatient care, and round-the-clock inpatient services. This facility is particularly skilled in techniques such as anger management, brief interventions, and cognitive behavioral therapy. Additionally, specialized programs are available for adult men and women, as well as for individuals who have suffered from intimate partner violence or domestic abuse. Emphasizing personalized care, the center fosters a secure and encouraging atmosphere for all patients pursuing effective recovery from addiction.

Ranch Creek Recovery

Located in Murrieta, CA, Ranch Creek Recovery delivers extensive addiction treatment options in a peaceful setting. The center specializes in hospital inpatient detox, treatment for substance use disorders, and tailored services for adults facing co-occurring substance use and significant mental health challenges, as well as for children with serious emotional issues. The program incorporates techniques such as anger management, brief interventions, and cognitive behavioral therapy, supporting both men and women, including those who have suffered from intimate partner or domestic violence. Ranch Creek Recovery is committed to providing high-quality, personalized care for adults and young adults, making it an excellent choice for individuals in need of effective and empathetic rehabilitation support.

Ranch Creek Recovery Inc

Ranch Creek Recovery Inc, located in Murrieta, CA, delivers thorough care for addiction, chemical dependency, and dual diagnoses in individuals of all ages. The center's inpatient hospital services ensure a secure and nurturing setting for detox and ongoing treatment. Employing therapeutic strategies such as anger management, cognitive behavioral therapy, and brief intervention techniques, the facility addresses the specific requirements of adult men, adult women, and survivors of domestic abuse. Catering to adults and young adults across the gender spectrum, this establishment focuses on high-standard care and personalized recovery plans for sustained well-being.

Ranch Recovery Centers Inc
Desert Hot Springs, CA

Ranch Recovery Centers Inc, located in Desert Hot Springs, CA, provides extensive residential rehabilitation designed for adult males. Their services encompass addiction recovery, withdrawal management, and care for dual-diagnosis mental health conditions. The curriculum features elements like 12-step program support, strategies for managing anger, and short-term therapeutic interventions. This establishment serves active military members, adult men, and those who have experienced domestic abuse. Catering to a broad age range including adults, seniors, and young adults, the center is dedicated to delivering effective treatment within a nurturing setting. For individuals in search of thorough and tailored addiction therapy, Ranch Recovery Centers Inc stands as a strong contender for a successful path to healing.

Rancho Milagro Recovery Inc

Rancho Milagro Recovery Inc, situated in Temecula, California, delivers thorough addiction care for adults and adolescents. They provide medical inpatient detox and treatment for substance dependence, alongside integrated care for co-occurring severe mental health conditions in adults and childhood emotional challenges. Employing proven methods like 12-step guidance, emotional regulation techniques, and brief counseling, Rancho Milagro Recovery Inc also features tailored tracks for active military members, adult men, and adult women, addressing the varied needs of their clientele. The center is committed to offering high-standard assistance and guidance to individuals pursuing sobriety.

Rancho San Antonio Boys Home Inc

Rancho San Antonio Boys Home Inc, situated in Chatsworth, CA, offers a thorough approach to substance abuse recovery, employing methods like 12-step guidance, emotional regulation training, and concise intervention techniques. They provide intensive outpatient services, standard outpatient care, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. The center is particularly adept at supporting adolescents, survivors of sexual abuse, and individuals with trauma histories, serving clients of all ages and genders. Rancho San Antonio Boys Home Inc is committed to providing excellent care for those pursuing freedom from addiction.

Rancho Recovery
Rancho Cucamonga, CA

Rancho Recovery, situated in Rancho Cucamonga, CA, provides a full spectrum of care for addiction. The center offers detox services, comprehensive substance abuse treatment, and tailored support for those with dual diagnoses of mental health disorders and substance dependence. Clients can access intensive outpatient, extended residential stays, and standard outpatient options. Treatment modalities include 12-step integration, emotional regulation techniques, and short-term counseling strategies. Rancho Recovery serves adult men and women, including survivors of sexual trauma, with a specific focus on adults and young adults, delivering personalized and effective treatment.

Radius Health
Saint Paul, MN

Radius Health, situated in Saint Paul, MN, provides extensive rehabilitation care. The center focuses on addiction recovery, supportive living arrangements, and integrated treatment for dual diagnoses involving mental health and substance use in both younger and older individuals. Employing outpatient and intensive outpatient options, the facility uses proven therapeutic techniques including anger management, cognitive behavioral therapy, and the Matrix Model. Radius Health offers distinct programs for active military members, teenagers, adult men, and individualized support for adult men and women, including seniors. Discover excellent care and successful recovery at Radius Health.

Ram Recovery
Baltimore, MD

Situated in Baltimore, MD, Ram Recovery specializes in delivering tailored substance use treatment services for both adults and young adults. The facility offers various options including intensive outpatient, outpatient, and treatments with methadone, buprenorphine, or naltrexone. Emphasizing a 12-step approach, along with strategies such as anger management and cognitive behavioral therapy, Ram Recovery customizes its methods to fit the unique requirements of each client. The center takes pride in offering distinctive programs designed for adult men, adult women, and individuals affected by intimate partner or domestic violence. Catering to both genders, Ram Recovery aims to create an all-encompassing and nurturing atmosphere for those pursuing recovery from addiction.

Ramey Estep Homes

Ramey Estep Homes, located in Rush, KY, provides exceptional treatment for substance use disorders along with focused care for adults facing co-occurring substance use and serious mental health challenges, as well as emotional issues in children. The center features various program lengths, including long-term, short-term, and 24-hour residential options, implementing evidence-based practices like 12-step facilitation, anger management, and cognitive behavioral therapy. Ramey Estep Homes is particularly noted for its customized programs catering to adult men and women, those who have suffered from domestic or intimate partner violence, and services designed for all genders among adults and young adults. The center is dedicated to offering high-quality support to assist individuals in their recovery process.

Ramon Velez Recovery Center

Situated in the Bronx, NY, the Ramon Velez Recovery Center specializes in outpatient treatment for substance use for both adults and children facing serious mental health issues concurrently. This center employs a range of targeted therapies, including anger management, cognitive behavioral therapy, and short intervention strategies. It features customized programs tailored for adult men, adult women, and those who have encountered domestic or intimate partner violence. Committed to delivering high-quality care, the center addresses the needs of both adults and young adults, providing outpatient options for methadone/buprenorphine or naltrexone. Services are designed to meet the specific needs of males and females in their journey towards recovery.

Ramon Velez Recovery Center

The Ramon Velez Recovery Center, situated in Bronx, NY, specializes in outpatient detoxification and comprehensive substance use treatment. They also provide dedicated support for those facing dual diagnoses, addressing both addiction and significant mental health or emotional challenges. Employing therapeutic techniques like cognitive behavioral therapy and anger management, the center designs personalized recovery plans for adult men and women, young adults, and individuals affected by domestic or intimate partner violence. Committed to exceptional care and customized approaches, this institution empowers clients on their journey toward sustained sobriety.

Raise the Bottom Training and

Raise the Bottom Training and provides thorough outpatient care for addiction in Boise, ID. This center focuses on addressing dual diagnoses, treating substance use disorders concurrently with significant mental health conditions in adults and severe emotional challenges in youth. Employing therapeutic methods such as anger management, cognitive behavioral therapy, and brief intervention strategies, the facility customizes its programs to suit each person's unique requirements. Specialized offerings exist for active military members, adult men, and women. Catering to adults and young adults irrespective of gender, Raise the Bottom Training and delivers high-caliber services including outpatient care, medication-assisted treatment (methadone/buprenorphine or naltrexone), and standard outpatient support.

Rappahannock Area Comm Servs Board

Situated in Stafford, VA, the Rappahannock Area Comm Servs Board delivers outpatient treatment for individuals, both adults and minors, who are facing substance use challenges alongside serious mental health disorders. This center emphasizes regular outpatient services that include anger management, relapse prevention strategies, and counseling for substance use disorders. With targeted programs designed for male and female adults, as well as those involved in the criminal justice system, the facility addresses the diverse needs of its clients. The center extends its services to both adults and older individuals, ensuring personalized care that caters to the specific circumstances of each person. The Rappahannock Area Comm Servs Board is committed to offering effective rehabilitation services in a nurturing and understanding setting.

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Rainforest Recovery Center, situated in Juneau, AK, delivers outpatient care for adults and young adults battling substance misuse. Their focus is on assisting individuals who are simultaneously experiencing substance use disorders and significant mental health challenges. The center offers diverse treatment options, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient services. Employing proven therapeutic methods like cognitive behavioral therapy and motivational incentives, Rainforest Recovery Center is committed to providing exceptional support. They have developed specialized services for those with dual diagnoses of mental health and substance use conditions, serving both men and women in their journey toward recovery.

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Nestled in Nampa, ID, Raise the Bottom Training and is dedicated to providing outpatient substance use disorder services for adults and adolescents facing co-occurring mental health conditions. The center offers medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care. Therapeutic modalities employed include anger management, brief intervention strategies, and cognitive behavioral therapy. Specialized support is available for active military personnel, adult men, and adult women, ensuring a broad spectrum of needs are met. Raise the Bottom Training and extends its comprehensive, supportive, and professional treatment options to adults and young adults, fostering a compassionate environment for recovery.

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Situated in Pocatello, ID, Raise the Bottom Training is dedicated to providing outpatient support for adults struggling with substance use disorders. They also address co-occurring mental health and substance use issues in both adult and pediatric populations. The facility offers medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside general outpatient services. Specific programs are available for active-duty military personnel, as well as men and women. Therapeutic interventions employed include anger management techniques, brief intervention strategies, and cognitive behavioral therapy. Serving a diverse clientele of adults and young adults, Raise the Bottom Training prioritizes effective, high-quality care to aid individuals in their recovery from addiction and mental health concerns.

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Rapid City, SD

Situated in Rapid City, SD, Rapid City serves as a premier rehabilitation center that delivers extensive services for individuals dealing with substance use issues, transitional housing, and co-occurring mental health conditions. The center offers a variety of programs, including intensive outpatient services and outpatient care tailored for both adults and young adults, especially those who have faced traumatic experiences. Employing proven methodologies such as cognitive behavioral therapy and motivational interviewing, Rapid City provides a nurturing atmosphere for men and women who are on their journey to recovery. With an emphasis on personalized treatment and positive outcomes, this center is committed to supporting clients in achieving enduring sobriety and mental health stability.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)