Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.
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Situated in Longmont, CO, the Redpoint Center presents an extensive array of rehabilitation services for both adults and youth facing challenges related to substance use disorders alongside mental health concerns. The center features intensive outpatient programs, day treatment sessions, and partial hospitalization, employing various strategies like 12-step methods, anger management classes, and brief intervention techniques. With tailored programs for active-duty military personnel, as well as specific offerings for men and women, the Redpoint Center addresses the needs of different populations. Notably, this facility provides transitional housing, a halfway house, and sober living arrangements to foster a nurturing recovery atmosphere. Individuals looking for effective care in a gender-specific environment will find the Redpoint Center to be an essential asset on their path to recovery.

Reed Behavioral Health, situated in Minneapolis, MN, delivers comprehensive outpatient treatment and support for adults and children facing substance use and co-occurring mental health conditions. Employing strategies such as 12-step facilitation, cognitive behavioral therapy, and brief intervention, the center offers expert care for those with trauma backgrounds and dual diagnoses. Customized plans are available for adults and young adults across the gender spectrum. Committed to high standards of care and scientifically proven methods, Reed Behavioral Health empowers individuals in their path to overcoming addiction and mental health struggles.

Situated in Beverly Hills, CA, Refine Recovery delivers an all-encompassing range of addiction treatment services tailored for both adults and young adults. The center features residential detox services, around-the-clock care, and short-term residential options. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, Refine Recovery addresses the needs of clients dealing with trauma, dual diagnosis of mental health and substance use disorders, as well as those struggling with pain in conjunction with addiction. Catering to both men and women, this facility is committed to providing top-notch care for individuals in pursuit of effective and customized solutions for substance use problems and related conditions.

Reform Recovery Center Inc, located in Minneapolis, MN, delivers a wide range of treatment options for individuals struggling with substance use. Designed for adults and young adults, the center features intensive outpatient, outpatient, and standard outpatient programs, employing techniques such as cognitive behavioral therapy, anger management, and brief interventions. With specific services aimed at adult men, women, and active duty military personnel, this facility addresses various requirements effectively. The center prides itself on providing customized care for both genders, ensuring that each patient receives tailored support. Individuals can anticipate effective, evidence-supported treatment within a nurturing atmosphere that fosters healing and recovery.

Region 8 Mental Health Services located in Canton, MS, provides outpatient treatment for adults struggling with substance use alongside significant mental health conditions, as well as support for emotionally disturbed children. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, this center serves active duty military members, young people, and adult males. Catering to all genders among adults and seniors, Region 8 Mental Health Services adopts a holistic method for rehabilitation. Their tailored programs and personalized treatment strategies reflect their dedication to delivering high-quality care to individuals facing addiction and mental health issues.

Reflections Detox Facility, located in Novato, CA, provides an extensive range of detox and substance abuse treatment options in a supportive residential environment. Their offerings include around-the-clock residential care as well as short-term programs tailored to various needs. This center focuses on 12-step facilitation while also incorporating distinct methods such as anger management and short intervention sessions. Additionally, it has specialized programs designed for active military members, along with services for adult men and women, accommodating a wide spectrum of clients. Reflections Detox Facility is dedicated to delivering quality care and assistance for adults and young adults striving for recovery from addiction.

Nestled in Lindon, UT, Reflections Outpatient is dedicated to providing tailored substance use recovery programs for adults and young adults managing co-occurring serious mental health conditions. They offer structured care through intensive outpatient, day treatment, and partial hospitalization programs. Their therapeutic approach incorporates methods such as 12-step facilitation, anger management techniques, and brief intervention strategies. This center serves adult men and women, including those who have faced intimate partner or domestic violence. Reflections Outpatient stands as a crucial support system for individuals pursuing healing and well-being within a nurturing setting designed to address their specific challenges.

Region IV MHS in Corinth, MS, provides extensive support for recovery and sober living. This facility is dedicated to addressing dual diagnoses involving substance abuse and significant mental health challenges for adults, along with emotional issues in younger individuals. They offer various residential options, including extended stays, shorter durations, and round-the-clock care, utilizing methods like 12-step program integration, emotional regulation training, and concise support strategies. Region IV MHS supports adult men and women, including those with histories of trauma. Serving a broad age range from adults to young adults, they provide distinct programs for both men and women. Discover personalized treatment and effective recovery pathways at this center.

Redwood Community Services Inc, situated in Ukiah, CA, delivers a variety of focused therapies for individuals of all ages grappling with substance abuse and concurrent mental health issues. They provide flexible care levels, including intensive outpatient, standard outpatient, and regular outpatient services, all customized using methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Their programs are designed for adolescents, adult men, and women, emphasizing individual needs. The facility also offers distinct treatment pathways for males and females. Redwood Community Services Inc is recognized for its all-encompassing support and dedication to effective recovery for those facing addiction and mental health obstacles.

Situated in Wayzata, MN, Reed Behavioral Health provides targeted interventions for individuals, both young and adult, grappling with addiction and co-occurring mental health conditions. Their multifaceted treatment options encompass intensive outpatient, standard outpatient, and flexible outpatient care. Employing proven therapeutic methods like cognitive behavioral therapy, motivational interviewing, and contingency management, the facility delivers personalized support designed for adult men, adult women, and those who have encountered trauma. Reed Behavioral Health is dedicated to delivering exceptional care and assistance to all genders on their journey toward overcoming substance dependence and mental health struggles.

Situated in Lees Summit, MO, ReDiscover provides all-encompassing care for individuals battling substance use disorders, including those experiencing concurrent severe mental health challenges. The center's offerings include intensive outpatient, standard outpatient, and day treatment services, employing methodologies like 12-step support, emotional regulation techniques, and brief therapeutic interventions. ReDiscover features tailored programs designed for active military members, adult men, and adult women, demonstrating a commitment to serving varied demographics. This facility welcomes adults and young adults of any gender, prioritizing the delivery of exceptional care to support individuals in their journey toward lasting recovery.

Region 4 Desoto, located in Hernando, MS, delivers a wide array of addiction recovery services for both adults and young adults. This center features intensive outpatient care, outpatient programs, and standard outpatient treatment options, addressing substance use disorders alongside co-occurring mental health challenges. Employing evidence-based techniques like cognitive behavioral therapy, brief interventions, and contingency management, the facility customizes its treatment strategies to meet the unique needs of each client. Additionally, special programs cater specifically to active military members, adult men, and adult women. Prioritizing high-quality support, Region 4 Desoto fosters a nurturing environment for healing and recovery for clients of all genders facing issues related to substance use and mental health.

Region 8 Mental Health Services located in Brookhaven, MS, provides outpatient support for individuals dealing with substance use and concurrent disorders for both adults and children. With expertise in 12-step programs, anger management, and brief intervention techniques, this center caters to the unique needs of active military personnel, teenagers, and adult males. Welcoming individuals of all ages and genders, the facility emphasizes high-quality care aimed at facilitating recovery. Featuring a variety of specialized programs and a comprehensive treatment approach, Region 8 Mental Health Services is committed to assisting individuals in attaining enduring sobriety and mental health.

Nestled in Fort Collins, CO, Redpoint North delivers a complete spectrum of recovery support for adults and young adults facing addiction. The center features intensive outpatient, day treatment, and partial hospitalization programs, utilizing proven methods like 12-step support, emotional regulation skills, and brief counseling. Redpoint North is particularly adept at addressing dual diagnoses of addiction and significant mental health conditions in adults, along with serious emotional challenges in younger individuals. Dedicated tracks for active military personnel, teenagers, and adult males ensure personalized treatment plans. With options for supported living arrangements and sober residences, Redpoint North is committed to offering effective, gender-informed care for individuals of all genders pursuing sobriety.

"Reflections of Hope LLP in Wilmington, NC, offers comprehensive substance use treatment through various outpatient formats, including methadone/buprenorphine or naltrexone treatment. This facility provides specialized programs for active duty military personnel, adult men, and adult women. With a focus on anger management, brief intervention, and cognitive behavioral therapy, the center caters to adults and young adults of both genders. The center's dedication to quality care and individualized treatment plans makes it a sought-after choice for those seeking effective and supportive rehabilitation services in the Wilmington area."

Region 8 Mental Health Services, located in Hazlehurst, MS, specializes in providing extensive addiction treatment options specifically for adult women facing issues related to substance use and co-occurring mental health disorders. The center offers a variety of programs, including long-term residential stays, outpatient services, and standard outpatient treatments, emphasizing strategies such as 12-step facilitation, anger management, and brief intervention techniques. Additionally, it features distinctive programs designed for active military personnel, adult women, and those impacted by intimate partner violence. Serving adults, seniors, and young adults, Region 8 Mental Health Services places a strong emphasis on addressing the unique needs of female clients. The facility is committed to delivering exceptional care and personalized support for individuals on their journey to recovery from addiction.

Region 8 Mental Health Services, located in Brandon, MS, offers an extensive selection of therapeutic programs designed to meet diverse requirements. This center focuses on detoxification, treatment for substance use disorders, and specialized assistance for individuals dealing with both substance use and severe mental health issues in adults, along with serious emotional challenges in children. The facility provides various treatment options, including intensive outpatient, outpatient, and day treatment programs, employing evidence-based techniques such as 12-step facilitation, anger management, and brief interventions. Additionally, Region 8 Mental Health Services features specialized initiatives for active military members, teenagers, and adult males. Catering to adults and seniors of all genders, this center prioritizes high-quality care customized to meet the distinct needs of each individual.

Region III Chem Dependency, located in Tupelo, MS, provides a wide range of addiction recovery services for both adults and adolescents facing challenges related to substance misuse. The center specializes in addressing the needs of clients with dual diagnosis, offering long-term residential care, outpatient services, and medication-assisted treatment options. Emphasizing the principles of 12-step programs, anger management, and cognitive behavioral strategies, Region III Chem Dependency adopts a comprehensive approach to rehabilitation. This facility is particularly noteworthy for its customized programs designed for those dealing with both mental health and substance use issues, accommodating individuals of all genders. Discover compassionate care and guidance in a supportive setting at this esteemed treatment center.

Region IV MHS located in Corinth, MS, provides outpatient services that focus on treating substance abuse and concurrent mental health challenges. Designed for both adults and young adults, this center employs regular outpatient practices grounded in evidence-based methods such as Cognitive Behavioral Therapy and Motivational Interviewing. Emphasizing a 12-step approach, the facility addresses the needs of clients with dual diagnoses. Region IV MHS is distinguished by its specific programs tailored for men and women, guaranteeing personalized and thorough care for every individual. Clients can anticipate receiving high-quality treatment and assistance in a friendly and supportive atmosphere at this center.

Region IV MHS in Corinth, MS, provides outpatient services for adults battling substance use disorders alongside co-occurring mental health challenges. Their offerings are designed for adults and seniors, incorporating methods such as 12-step support, emotional regulation skills, and short-term therapeutic strategies. They also feature distinct programs for young people, adult men, and adult women, delivering personalized support to address a wide array of individual circumstances. The center prioritizes high standards and proven therapeutic techniques, guaranteeing thorough assistance for those on the path to recovery. Regardless of gender, individuals will find a nurturing atmosphere at Region IV MHS, fostering both healing and personal development.

Region Ten Community Services Board in Charlottesville, VA, is dedicated to providing comprehensive, research-backed therapeutic services for individuals grappling with substance use and co-occurring mental health challenges, serving both younger and adult populations. Their offerings include structured intensive outpatient programs, general outpatient services, and a day treatment model, emphasizing techniques such as 12-step facilitation, anger management strategies, and concise intervention approaches. The facility distinguishes itself with specialized support for active military personnel, teenagers, and adult males, ensuring a wide spectrum of demographic needs are met. Their care extends to seniors and adults of all gender identities. Clients can anticipate a personalized, high-quality treatment experience within a nurturing and expert setting.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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