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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Restore Health and Wellness Center LLC

Restore Health and Wellness Center LLC, located in Canoga Park, CA, provides a full spectrum of substance abuse recovery services for adults and adolescents. Their offerings include intensive outpatient, standard outpatient, and partial hospitalization programs. The center utilizes therapeutic modalities such as 12-step program integration, anger control strategies, and short-term counseling techniques, customizing each plan to suit individual requirements. They are particularly adept at assisting individuals with trauma histories and those facing dual diagnoses of mental health and addiction issues, offering distinct care tracks for men and women. Restore Health and Wellness Center LLC is dedicated to delivering high-caliber support and fostering a nurturing setting to guide individuals toward lasting sobriety.

Restore Health and Wellness Center LLC

Restore Health and Wellness Center LLC, located in Chatsworth, CA, provides all-encompassing addiction treatment for adults and adolescents within a nurturing inpatient environment. The center excels in detox and substance abuse care, featuring extended inpatient stays, inpatient detox services, and round-the-clock inpatient assistance. Their therapeutic methods incorporate 12-step support, emotional regulation training, and short-term counseling strategies. Distinctive services are available for those who have experienced trauma or are dealing with concurrent mental health conditions. Offering tailored care for men and women alike, Restore Health and Wellness Center LLC is dedicated to delivering effective, individualized recovery plans for all individuals pursuing sobriety.

Resurgence California Alcohol and

Resurgence California Alcohol and Drug Addiction Treatment Center in Costa Mesa, CA, provides thorough addiction care for adults and young adults. They offer hospital-based inpatient detoxification and treatment, emphasizing 12-step facilitation, anger management, and brief intervention strategies. Dedicated programs are offered for active duty military, men, and women. This center is equipped to handle co-occurring substance use and severe mental health conditions, delivering high-quality support for all clients. For those looking for expert addiction treatment in a nurturing setting, this center is committed to fostering enduring recovery.

Retreat at South Connecticut

The Retreat at South Connecticut, located in New Haven, CT, provides an extensive array of services for addiction treatment. This center features specialized programs designed for active duty military personnel, adolescents, and adult males, offering residential detox services, round-the-clock residential support, and short-term treatment options. The facility employs various therapeutic methods, including 12-step facilitation, anger management, and brief intervention strategies, to effectively tackle substance use disorders alongside co-occurring mental health challenges in adults, as well as serious emotional issues in children. Accommodating both male and female clients of all ages, the Retreat at South Connecticut prioritizes high-quality care and tailored treatment plans aimed at fostering sustainable recovery.

Retreat Behavioral Health

Retreat Behavioral Health, positioned in Akron, PA, provides extensive treatment options for adults grappling with substance use disorders alongside significant mental health challenges, as well as for children facing severe emotional difficulties. Their programs, including outpatient and intensive outpatient options, employ proven methodologies like cognitive behavioral therapy, counseling for substance use disorders, and therapy addressing trauma. With a strong emphasis on the needs of adolescents, Retreat Behavioral Health delivers personalized care for young males and females alike. The center's dedication to high-quality, customized treatment establishes it as an excellent option for individuals pursuing successful rehabilitation in a nurturing atmosphere.

Retreat Behavioral Health

Retreat Behavioral Health, situated in Lake Worth, FL, offers an extensive array of rehabilitation programs aimed at adults and young adults facing challenges related to substance use and concurrent mental health issues. This facility features hospital-based inpatient detoxification and treatment with round-the-clock medical support. Catering to various groups, including active duty military personnel, adult men, and women, Retreat Behavioral Health recognizes the unique needs of its clientele. The center employs evidence-based methodologies such as 12-step support, anger management techniques, and brief therapeutic interventions, ensuring a personalized approach for every individual. With its commitment to high-quality, customized care, the center serves as an essential resource for those in pursuit of effective and empathetic rehabilitation options.

Retreat Behavioral Health Service Ctr

Retreat Behavioral Health Service Center located in West Palm Beach, FL, provides various levels of care including intensive outpatient programs, standard outpatient services, and day treatment designed for those dealing with substance abuse, mental health challenges, and emotional issues. The center incorporates cognitive behavioral therapy alongside counseling for substance use disorders, and also features telemedicine options for therapy. Programs are specifically designed to meet the needs of adult men, women, and those who have faced intimate partner violence. Catering to both adults and young adults, Retreat Behavioral Health Service Center delivers targeted support for clients of all genders, ensuring effective care through well-rounded treatment strategies and individualized plans.

Retreat of Broward Inc
Pompano Beach, FL

Retreat of Broward Inc, situated in Pompano Beach, Florida, delivers thorough substance abuse rehabilitation. The facility provides inpatient hospital detox and care for individuals struggling with addiction. Furthermore, distinct programs are designed for those experiencing co-occurring severe mental health conditions. Retreat of Broward Inc employs diverse therapeutic methods, including 12-step support, emotional regulation training, and focused counseling to promote well-rounded recovery. Tailored services are offered for active military members, adult men, and women. This center, which welcomes adults and young adults of all genders, is dedicated to delivering high-quality treatment in a nurturing setting.

ReVIDA Recovery Centers
Johnson City, TN

ReVIDA Recovery Centers located in Johnson City, TN, specializes in outpatient treatment for adults and young adults dealing with substance use issues. This center offers targeted outpatient services including methadone/buprenorphine or naltrexone therapy, in addition to standard outpatient care. Emphasizing personalized treatment, the facility employs techniques such as 12-step programs, anger management strategies, and brief interventions. Catering to both men and women, ReVIDA Recovery Centers customizes its programs to address the distinct needs of each client. For those in search of a thorough and supportive addiction treatment option in Johnson City, the center’s dedication to high-quality care and individualized plans may provide the help you need.

Revive Detox
Los Angeles, CA

Revive Detox in Los Angeles, CA, is a leading facility providing extended residential care and round-the-clock support for individuals undergoing detoxification and addressing substance use disorders. They have developed particular expertise in supporting clients with dual diagnoses and those with a history of sexual trauma. Employing evidence-based approaches such as 12-step integration, motivational interviewing, and cognitive behavioral therapy, Revive Detox crafts personalized treatment plans. The center is dedicated to offering excellent care to adults and young adults across all genders within a nurturing atmosphere. For those in search of thorough and empathetic addiction recovery services, Revive Detox offers a complete spectrum of assistance for the path to healing.

Revive Ministries Inc
Nicholasville, KY

Revive Ministries Inc, located in Nicholasville, KY, presents a holistic selection of services aimed at addressing addiction for both adults and young adults. The center prioritizes detox services, treatment for substance use, and specialized assistance for individuals grappling with concurrent mental health challenges. It features both intensive outpatient and outpatient programs, offering options like methadone/buprenorphine and naltrexone treatments. The methods employed here include 12-step facilitation, brief interventions, and cognitive behavioral therapy. Additionally, the facility has distinct programs designed specifically for active military personnel, as well as separate tracks for adult men and women. Revive Ministries Inc is committed to delivering personalized care and support to help clients on their path to recovery from addiction.

Restorative Management Corporation

Restorative Management Corporation, located in Newburgh, NY, delivers an extensive range of substance abuse treatment options customized to meet diverse individual requirements. The center includes intensive outpatient programs, standard outpatient services, and medication-assisted treatments using methadone, buprenorphine, or naltrexone. With techniques such as anger management, brief interventions, and cognitive behavioral therapy, this facility focuses on supporting adult women, individuals who have faced intimate partner or domestic violence, and those struggling with both mental health and substance use disorders. Catering to adults as well as children and adolescents of all genders, Restorative Management Corporation is dedicated to providing exceptional care and assistance to individuals seeking recovery from addiction.

Resurge Recovery
Cincinnati, OH

Resurge Recovery, located in Cincinnati, OH, specializes in a wide array of addiction rehabilitation services for both adults and young adults. The center provides intensive outpatient treatment, detoxification services on an outpatient basis, and various other outpatient support options employing evidence-based methods. These include strategies like 12-step facilitation, anger management, and brief interventions. Additionally, there are specialized programs aimed at supporting individuals who have endured intimate partner violence, domestic violence, sexual abuse, and traumatic experiences. With an emphasis on addressing both substance use and mental health disorders concurrently, Resurge Recovery offers personalized care tailored to the needs of both men and women. The facility is committed to offering exceptional, individualized treatment to aid clients in their path toward recovery.

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Restore Health and Wellness Center LLC, based in Chatsworth, CA, provides an extensive array of long-term residential and detox services for both adults and young adults dealing with substance use issues. The center is adept in 12-step facilitation, anger management, and brief intervention techniques, designed to aid individuals on their recovery path. Emphasizing support for those who have faced trauma and individuals with co-occurring mental health and substance use challenges, the facility offers personalized treatment plans to cater to unique requirements. Restore Health and Wellness Center LLC is inclusive, extending its services to both men and women, while fostering a safe and nurturing atmosphere for personal healing and development.

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Restore Health and Wellness Center LLC in Chatsworth, CA, is dedicated to providing extensive addiction recovery programs for adults and young adults. They offer various levels of care, including extended residential stays, inpatient detoxification, and round-the-clock residential services. Their therapeutic approach emphasizes 12-step integration, techniques for managing anger, and concise intervention strategies, making them well-equipped to assist individuals dealing with trauma and concurrent mental health and substance use conditions. Restore Health and Wellness Center LLC welcomes both male and female participants, fostering a nurturing and accepting atmosphere. Discover exceptional care and personalized recovery journeys at this premier facility committed to overall health and well-being.

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Retreat at Lancaster County PA LLC, situated in Lansdale, PA, delivers complete addiction treatment and targeted support for individuals managing both substance use disorders and significant mental health challenges, as well as children with serious emotional disturbances. The facility features intensive outpatient, general outpatient, and day treatment options. Employing proven therapeutic methods such as cognitive behavioral therapy, addiction counseling, and trauma-informed therapy, the center customizes care to each person's unique requirements. Catering to adolescents through dedicated programs and serving both adults and children, Retreat at Lancaster County PA LLC ensures high-quality care in a nurturing setting for all clients.

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RevCore Recovery Center/Manhattan, situated in Jackson Heights, NY, is dedicated to providing outpatient substance use disorder services for adults. They are equipped to address individuals with co-occurring serious mental health conditions or emotional disruptions. The center features distinct programs designed for adult men and women, alongside support for survivors of intimate partner or domestic violence. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Catering to adults and young adults, regardless of gender, this establishment offers outpatient treatment utilizing methadone, buprenorphine, or naltrexone. RevCore Recovery Center/Manhattan is committed to delivering exceptional care individualized for each client.

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RevCore Recovery Center of Manhattan, located in New York, NY, provides expert care for adults and adolescents struggling with addiction and co-occurring mental health conditions or emotional challenges. The center offers comprehensive outpatient and intensive outpatient services, incorporating medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic approach includes anger management, brief intervention strategies, and cognitive behavioral therapy, serving both adult men and women, as well as those affected by domestic violence. RevCore distinguishes itself with gender-specific programming, ensuring a personalized and effective recovery journey built on proven methods.

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Revitalized Behavioral Healthcare LLC in Toledo, OH, provides extensive care for adults grappling with substance use alongside co-occurring mental health conditions, as well as children experiencing significant emotional challenges. They employ proven strategies like cognitive behavioral therapy and the Matrix Model within their structured outpatient and day treatment offerings. The facility caters to specific needs with dedicated programs for teenagers, adult men, and women, extending personalized support to adults and seniors irrespective of gender. By prioritizing brief interventions and customized treatment paths, Revitalized Behavioral Healthcare LLC guarantees effective recovery in a nurturing setting.

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Nicholasville, KY

Revive Ministries Inc, located in Nicholasville, KY, provides targeted treatment for substance use disorders specifically for adult males. The center offers various options, including intensive outpatient services, long-term residential care, and outpatient programs designed to meet the unique needs of each individual. Emphasizing methods like 12-step support, brief interventions, and cognitive behavioral therapy, this facility ensures thorough and effective treatment. Distinctive programs are available for active-duty military members, adult men, and individuals who have faced intimate partner violence. Catering to adults, seniors, and young adults, Revive Ministries Inc operates exclusively for men, allowing for focused and personalized support. Discover exceptional care and effective recovery solutions at this esteemed rehabilitation center.

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Revived Essence Recovery, situated in Morehead, KY, provides dedicated substance abuse rehabilitation for adult women. The center offers extended, brief, and round-the-clock inpatient services for those facing simultaneous addiction and significant mental health challenges. Employing methodologies like 12-step encouragement, emotional regulation training, and short-term intervention strategies, Revived Essence Recovery crafts personalized care paths. This personalized method guarantees that both adult and young adult clients receive excellent support for their addiction and psychological well-being. For a thorough and encouraging path to healing, Revived Essence Recovery is available to assist.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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