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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Retreat at South Connecticut

The Retreat at South Connecticut, located in New Haven, CT, provides an extensive array of services for addiction treatment. This center features specialized programs designed for active duty military personnel, adolescents, and adult males, offering residential detox services, round-the-clock residential support, and short-term treatment options. The facility employs various therapeutic methods, including 12-step facilitation, anger management, and brief intervention strategies, to effectively tackle substance use disorders alongside co-occurring mental health challenges in adults, as well as serious emotional issues in children. Accommodating both male and female clients of all ages, the Retreat at South Connecticut prioritizes high-quality care and tailored treatment plans aimed at fostering sustainable recovery.

Retreat Behavioral Health

Retreat Behavioral Health, situated in Lake Worth, FL, offers an extensive array of rehabilitation programs aimed at adults and young adults facing challenges related to substance use and concurrent mental health issues. This facility features hospital-based inpatient detoxification and treatment with round-the-clock medical support. Catering to various groups, including active duty military personnel, adult men, and women, Retreat Behavioral Health recognizes the unique needs of its clientele. The center employs evidence-based methodologies such as 12-step support, anger management techniques, and brief therapeutic interventions, ensuring a personalized approach for every individual. With its commitment to high-quality, customized care, the center serves as an essential resource for those in pursuit of effective and empathetic rehabilitation options.

Retreat Behavioral Health Service Ctr

Retreat Behavioral Health Service Center located in West Palm Beach, FL, provides various levels of care including intensive outpatient programs, standard outpatient services, and day treatment designed for those dealing with substance abuse, mental health challenges, and emotional issues. The center incorporates cognitive behavioral therapy alongside counseling for substance use disorders, and also features telemedicine options for therapy. Programs are specifically designed to meet the needs of adult men, women, and those who have faced intimate partner violence. Catering to both adults and young adults, Retreat Behavioral Health Service Center delivers targeted support for clients of all genders, ensuring effective care through well-rounded treatment strategies and individualized plans.

Retreat of Broward Inc
Pompano Beach, FL

Retreat of Broward Inc, situated in Pompano Beach, Florida, delivers thorough substance abuse rehabilitation. The facility provides inpatient hospital detox and care for individuals struggling with addiction. Furthermore, distinct programs are designed for those experiencing co-occurring severe mental health conditions. Retreat of Broward Inc employs diverse therapeutic methods, including 12-step support, emotional regulation training, and focused counseling to promote well-rounded recovery. Tailored services are offered for active military members, adult men, and women. This center, which welcomes adults and young adults of all genders, is dedicated to delivering high-quality treatment in a nurturing setting.

Revive Detox
Los Angeles, CA

Revive Detox in Los Angeles, CA, is a leading facility providing extended residential care and round-the-clock support for individuals undergoing detoxification and addressing substance use disorders. They have developed particular expertise in supporting clients with dual diagnoses and those with a history of sexual trauma. Employing evidence-based approaches such as 12-step integration, motivational interviewing, and cognitive behavioral therapy, Revive Detox crafts personalized treatment plans. The center is dedicated to offering excellent care to adults and young adults across all genders within a nurturing atmosphere. For those in search of thorough and empathetic addiction recovery services, Revive Detox offers a complete spectrum of assistance for the path to healing.

Revive Ministries Inc
Nicholasville, KY

Revive Ministries Inc, located in Nicholasville, KY, presents a holistic selection of services aimed at addressing addiction for both adults and young adults. The center prioritizes detox services, treatment for substance use, and specialized assistance for individuals grappling with concurrent mental health challenges. It features both intensive outpatient and outpatient programs, offering options like methadone/buprenorphine and naltrexone treatments. The methods employed here include 12-step facilitation, brief interventions, and cognitive behavioral therapy. Additionally, the facility has distinct programs designed specifically for active military personnel, as well as separate tracks for adult men and women. Revive Ministries Inc is committed to delivering personalized care and support to help clients on their path to recovery from addiction.

Reward Path Recovery Center

Reward Path Recovery Center, located in Santa Paula, CA, provides extensive treatment for addiction for both adults and young adults. The center features long-term residential programs, detoxification services, and round-the-clock residential assistance. Emphasizing a 12-step approach, anger management, and short interventions, the services are designed for those dealing with co-occurring substance use and severe mental health challenges or emotional issues. With a specialization in trauma recovery, the center offers personalized treatment plans for men and women alike. Reward Path Recovery Center is dedicated to ensuring top-notch care to aid individuals in achieving sobriety and improved mental health.

Richard C Ward Addiction Trt Center

Situated in Middletown, NY, the Richard C Ward Addiction Trt Center provides tailored, top-notch services for adult women, seniors, and young adults facing challenges related to substance use and accompanying mental health issues. This center features both residential and short-term residential options, utilizing methodologies such as 12-step programs, anger management, and brief intervention techniques. What distinguishes this facility is its focus on individuals who have undergone trauma and those with dual diagnoses, alongside a commitment to female clients. By prioritizing personalized care and comprehensive support, the center aims to facilitate enduring recovery and enhanced mental health for its clients.

Ridgeview
Oak Ridge, TN

Situated in Oak Ridge, TN, Ridgeview serves as a leading rehabilitation facility that delivers tailored treatment programs for detox, substance abuse, and concurrent mental health challenges in both adults and children. Emphasizing inpatient hospital care and around-the-clock assistance, the center utilizes a variety of evidence-supported methods, such as anger management, brief intervention, and cognitive behavioral therapy. Ridgeview distinguishes itself with customized programs specifically designed for pregnant and postpartum women, individuals with co-occurring disorders, and those involved in the legal system. Catering to adults and seniors of all genders, Ridgeview is dedicated to providing high-quality, gender-sensitive care to help individuals navigate their recovery journey.

Richmond Behavioral Health Authority

Richmond Behavioral Health Authority in Richmond, VA, delivers extensive support for recovery. This establishment concentrates on addressing addiction and accompanying mental health challenges for individuals of all ages. They provide structured intensive outpatient and standard outpatient care. Key treatment modalities include anger management, rapid intervention, and cognitive behavioral therapy. Specialized services are available for young people, individuals with combined conditions, and those involved with legal proceedings. Catering to adults and older adults irrespective of gender, Richmond Behavioral Health Authority is committed to high-standard healing by employing tailored strategies and scientifically proven methods.

Richmond State Hospital

Richmond State Hospital, situated in Richmond, Indiana, provides focused inpatient care for individuals dealing with substance use issues and concurrent mental health challenges for both adults and youth. The center employs proven methodologies, including 12-step support, cognitive behavioral therapy, and strategies for managing anger, to ensure holistic care that meets the specific requirements of each client. Its distinctive programs address the needs of those facing both chronic pain and addiction. Committed to delivering high-quality, individualized treatment, Richmond State Hospital welcomes people of all genders aiming for recovery in a nurturing and healing atmosphere.

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Retreat at Lancaster County PA LLC, situated in Lansdale, PA, delivers complete addiction treatment and targeted support for individuals managing both substance use disorders and significant mental health challenges, as well as children with serious emotional disturbances. The facility features intensive outpatient, general outpatient, and day treatment options. Employing proven therapeutic methods such as cognitive behavioral therapy, addiction counseling, and trauma-informed therapy, the center customizes care to each person's unique requirements. Catering to adolescents through dedicated programs and serving both adults and children, Retreat at Lancaster County PA LLC ensures high-quality care in a nurturing setting for all clients.

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RevCore Recovery Center/Manhattan, situated in Jackson Heights, NY, is dedicated to providing outpatient substance use disorder services for adults. They are equipped to address individuals with co-occurring serious mental health conditions or emotional disruptions. The center features distinct programs designed for adult men and women, alongside support for survivors of intimate partner or domestic violence. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Catering to adults and young adults, regardless of gender, this establishment offers outpatient treatment utilizing methadone, buprenorphine, or naltrexone. RevCore Recovery Center/Manhattan is committed to delivering exceptional care individualized for each client.

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RevCore Recovery Center of Manhattan, located in New York, NY, provides expert care for adults and adolescents struggling with addiction and co-occurring mental health conditions or emotional challenges. The center offers comprehensive outpatient and intensive outpatient services, incorporating medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic approach includes anger management, brief intervention strategies, and cognitive behavioral therapy, serving both adult men and women, as well as those affected by domestic violence. RevCore distinguishes itself with gender-specific programming, ensuring a personalized and effective recovery journey built on proven methods.

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Revitalized Behavioral Healthcare LLC in Toledo, OH, provides extensive care for adults grappling with substance use alongside co-occurring mental health conditions, as well as children experiencing significant emotional challenges. They employ proven strategies like cognitive behavioral therapy and the Matrix Model within their structured outpatient and day treatment offerings. The facility caters to specific needs with dedicated programs for teenagers, adult men, and women, extending personalized support to adults and seniors irrespective of gender. By prioritizing brief interventions and customized treatment paths, Revitalized Behavioral Healthcare LLC guarantees effective recovery in a nurturing setting.

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Nicholasville, KY

Revive Ministries Inc, located in Nicholasville, KY, provides targeted treatment for substance use disorders specifically for adult males. The center offers various options, including intensive outpatient services, long-term residential care, and outpatient programs designed to meet the unique needs of each individual. Emphasizing methods like 12-step support, brief interventions, and cognitive behavioral therapy, this facility ensures thorough and effective treatment. Distinctive programs are available for active-duty military members, adult men, and individuals who have faced intimate partner violence. Catering to adults, seniors, and young adults, Revive Ministries Inc operates exclusively for men, allowing for focused and personalized support. Discover exceptional care and effective recovery solutions at this esteemed rehabilitation center.

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Revived Essence Recovery, situated in Morehead, KY, provides dedicated substance abuse rehabilitation for adult women. The center offers extended, brief, and round-the-clock inpatient services for those facing simultaneous addiction and significant mental health challenges. Employing methodologies like 12-step encouragement, emotional regulation training, and short-term intervention strategies, Revived Essence Recovery crafts personalized care paths. This personalized method guarantees that both adult and young adult clients receive excellent support for their addiction and psychological well-being. For a thorough and encouraging path to healing, Revived Essence Recovery is available to assist.

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Situated in Morehead, KY, Revived Essence Recovery is dedicated to providing targeted substance use support for adult women. The center offers intensive outpatient, outpatient, and transitional living options, with a particular emphasis on addressing both addiction and significant mental health challenges. Their treatment strategies incorporate 12-step facilitation, anger management techniques, and brief intervention methods, all customized to suit each person's unique journey. Revived Essence Recovery is committed to delivering high-caliber care to adults, seniors, and young adults looking for a nurturing space to begin their healing process. Their distinct, personalized approach distinguishes Revived Essence Recovery as a vital resource for individuals pursuing lasting recovery.

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Morehead, KY

Revived Recovery, located in Morehead, KY, specializes in treating adults with substance use disorders alongside serious mental health issues, as well as addressing emotional challenges in children. The center offers a range of services, including intensive outpatient programming, long-term residential care, and standard outpatient treatment. Their therapeutic methods include 12-step facilitation, anger management, and short-term interventions. Revived Recovery provides customized programs for adult men and also caters to survivors of intimate partner violence, domestic violence, and sexual abuse. Primarily focused on male clients, the center is dedicated to delivering high-quality care and support for individuals in need of thorough rehabilitation services.

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Revived Recovery Transitional Care, situated in Morehead, KY, provides individualized substance abuse treatment coupled with transitional housing specifically for adult males. The center emphasizes a range of therapeutic practices, including 12-step support, anger management strategies, and focused intervention approaches. Offering short-term residential care, the facility maintains a nurturing atmosphere. With a specialization in serving adult and young adult men, it ensures continuous support and a commitment to quality treatment. For those in search of an all-encompassing recovery program within a well-organized framework, this center presents a tailored methodology for overcoming addiction.

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Bridgewater, NJ

Richard Hall CHWC in Bridgewater, NJ, provides specialized care for adults and children struggling with substance use and co-occurring mental health issues through intensive outpatient and outpatient programs. Their services include 12-step facilitation, anger management techniques, and brief intervention strategies. The center has a particular expertise in supporting individuals who have experienced trauma and those managing dual diagnoses. They offer customized treatment plans for adults and young adults, respecting all gender identities. Richard Hall CHWC is dedicated to delivering high-quality, personalized rehabilitation services for a holistic recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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