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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Reward Path Recovery Center

Reward Path Recovery Center, located in Santa Paula, CA, provides extensive treatment for addiction for both adults and young adults. The center features long-term residential programs, detoxification services, and round-the-clock residential assistance. Emphasizing a 12-step approach, anger management, and short interventions, the services are designed for those dealing with co-occurring substance use and severe mental health challenges or emotional issues. With a specialization in trauma recovery, the center offers personalized treatment plans for men and women alike. Reward Path Recovery Center is dedicated to ensuring top-notch care to aid individuals in achieving sobriety and improved mental health.

Richard C Ward Addiction Trt Center

Situated in Middletown, NY, the Richard C Ward Addiction Trt Center provides tailored, top-notch services for adult women, seniors, and young adults facing challenges related to substance use and accompanying mental health issues. This center features both residential and short-term residential options, utilizing methodologies such as 12-step programs, anger management, and brief intervention techniques. What distinguishes this facility is its focus on individuals who have undergone trauma and those with dual diagnoses, alongside a commitment to female clients. By prioritizing personalized care and comprehensive support, the center aims to facilitate enduring recovery and enhanced mental health for its clients.

Ridgeview
Oak Ridge, TN

Situated in Oak Ridge, TN, Ridgeview serves as a leading rehabilitation facility that delivers tailored treatment programs for detox, substance abuse, and concurrent mental health challenges in both adults and children. Emphasizing inpatient hospital care and around-the-clock assistance, the center utilizes a variety of evidence-supported methods, such as anger management, brief intervention, and cognitive behavioral therapy. Ridgeview distinguishes itself with customized programs specifically designed for pregnant and postpartum women, individuals with co-occurring disorders, and those involved in the legal system. Catering to adults and seniors of all genders, Ridgeview is dedicated to providing high-quality, gender-sensitive care to help individuals navigate their recovery journey.

Richmond Behavioral Health Authority

Richmond Behavioral Health Authority in Richmond, VA, delivers extensive support for recovery. This establishment concentrates on addressing addiction and accompanying mental health challenges for individuals of all ages. They provide structured intensive outpatient and standard outpatient care. Key treatment modalities include anger management, rapid intervention, and cognitive behavioral therapy. Specialized services are available for young people, individuals with combined conditions, and those involved with legal proceedings. Catering to adults and older adults irrespective of gender, Richmond Behavioral Health Authority is committed to high-standard healing by employing tailored strategies and scientifically proven methods.

Ridgeview
La Follette, TN

Ridgeview, situated in La Follette, TN, provides outpatient treatment for substance use disorders in both adults and children facing simultaneous mental health challenges. The center's offerings include anger management, brief interventions, and cognitive behavioral therapy. With a focus on individuals with dual diagnoses, it serves those connected to the criminal justice system as well as pregnant and postpartum women, accommodating clients of all genders, including seniors. Ridgeview is committed to delivering exceptional care within a nurturing environment, making it a prime option for those in need of thorough and effective rehabilitation services.

RHA Health Services
Asheville, NC

Nestled in Asheville, NC, RHA Health Services stands as a beacon of comprehensive rehabilitation, dedicated to assisting adults and seniors navigating the complexities of substance use disorders and co-occurring mental health challenges. Their offerings encompass robust intensive outpatient treatment, flexible outpatient services, and targeted medication-assisted treatment including methadone, buprenorphine, or naltrexone. Employing proven methodologies like cognitive behavioral therapy and anger management techniques, the center prioritizes exceptional care crafted around each person's unique journey. RHA Health Services welcomes both men and women, featuring distinct programs tailored for adult men, adult women, and individuals impacted by intimate partner or domestic violence. For those in search of specialized, empathetic support within a nurturing setting, this center provides a well-rounded path toward lasting recovery.

Rigel Recovery Residential Services

Rigel Recovery Residential Services, located in Marietta, OH, provides extensive treatment for adult individuals facing substance use issues, including those with concurrent serious mental health challenges. The center features a variety of residential options, including long-term and short-term stays, as well as 24-hour care. It offers personalized treatment plans utilizing methods like 12-step programs, anger management techniques, and brief intervention strategies. Additionally, the center has specialized programs for adult men, adult women, and those who have encountered trauma. Rigel Recovery Residential Services is dedicated to delivering high-quality care and customized support for both adults and young adults of all genders, guiding them toward sustainable recovery.

Rigel Recovery Residential Services

Rigel Recovery Residential Services located in Marietta, OH, provides an extensive array of treatment programs tailored for both adults and youth dealing with substance use disorders alongside severe mental health challenges. The center features various treatment options including intensive outpatient programs, regular outpatient care, and alternative treatments involving methadone, buprenorphine, or naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, the facility is equipped to meet the distinct requirements of adult males, adult females, and adolescents. Rigel Recovery Residential Services prides itself on offering specialized programs designed for both genders, delivering high-quality care and tailored support for those on the path to recovery from addiction.

Ridgeview
Wartburg, TN

Ridgeview, situated in Wartburg, TN, is a full-service rehabilitation facility providing community-based care for adults struggling with substance use and concurrent mental health conditions, as well as children experiencing significant emotional challenges. Our therapeutic approach incorporates proven methods like anger management, brief intervention, and cognitive behavioral therapy. Ridgeview has particular expertise in supporting individuals with dual diagnoses, those involved in the justice system, and expectant or new mothers. Our programs are designed for adults and older adults, irrespective of gender, emphasizing personalized treatment strategies to foster sustained recovery.

RHA Health Services
Lumberton, NC

RHA Health Services in Lumberton, NC, specializes in comprehensive care for adults facing substance use disorders and co-occurring mental health conditions, alongside children with significant emotional challenges. They offer a spectrum of services, including intensive outpatient, outpatient, and day treatment, employing evidence-based therapeutic modalities like anger management, cognitive behavioral therapy, and the Matrix Model. The center features individualized treatment plans designed for adolescents, adult men, and adult women. RHA Health Services welcomes individuals of all genders across both adult and youth populations, delivering high-quality, supportive rehabilitation.

Ridgeview
Harriman, TN

Situated in Harriman, TN, Ridgeview provides a wide range of outpatient rehabilitation services designed for both adults and children coping with substance use disorders along with concurrent mental health challenges. This center focuses on anger management, cognitive behavioral therapy, and short-term interventions. Customized programs are available for individuals involved with the criminal justice system, pregnant or postpartum women, and those experiencing co-occurring disorders. Ridgeview also offers outpatient treatments with methadone/buprenorphine and emphasizes personalized treatment strategies. Catering to adults and seniors of all genders, Ridgeview is dedicated to delivering high-quality care and support for those in need of effective rehabilitation options.

Ridgeview Institute of Monroe

Ridgeview Institute of Monroe, located in Monroe, GA, provides extensive treatment options for individuals of all ages struggling with addiction and mental health issues. Their expertise encompasses detox, substance abuse care, and dual diagnosis, delivered through inpatient hospital services utilizing cognitive behavioral therapy. Distinctive offerings include specialized care for adult men, women, and those with trauma histories. Ridgeview Institute of Monroe prioritizes personalized healing through dedicated treatment paths for adults and children, and distinct programs for men and women. Discover effective, research-backed treatment at this respected recovery facility.

RHA Health Services Inc

RHA Health Services Inc, situated in Bakersville, NC, provides thorough substance use care for adults and youth experiencing dual mental health challenges. Their offerings encompass intensive outpatient and standard outpatient programs, featuring methadone and buprenorphine options. The facility is equipped with specific tracks for those impacted by domestic violence, sexual assault, and trauma, fostering a secure environment for recovery. Employing proven methods like 12-step facilitation and anger management, they serve both male and female individuals. RHA Health Services Inc is dedicated to delivering high-quality support for those on the path to overcoming addiction and trauma.

Richmond State Hospital

Richmond State Hospital, situated in Richmond, Indiana, provides focused inpatient care for individuals dealing with substance use issues and concurrent mental health challenges for both adults and youth. The center employs proven methodologies, including 12-step support, cognitive behavioral therapy, and strategies for managing anger, to ensure holistic care that meets the specific requirements of each client. Its distinctive programs address the needs of those facing both chronic pain and addiction. Committed to delivering high-quality, individualized treatment, Richmond State Hospital welcomes people of all genders aiming for recovery in a nurturing and healing atmosphere.

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Situated in Morehead, KY, Revived Essence Recovery is dedicated to providing targeted substance use support for adult women. The center offers intensive outpatient, outpatient, and transitional living options, with a particular emphasis on addressing both addiction and significant mental health challenges. Their treatment strategies incorporate 12-step facilitation, anger management techniques, and brief intervention methods, all customized to suit each person's unique journey. Revived Essence Recovery is committed to delivering high-caliber care to adults, seniors, and young adults looking for a nurturing space to begin their healing process. Their distinct, personalized approach distinguishes Revived Essence Recovery as a vital resource for individuals pursuing lasting recovery.

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Morehead, KY

Revived Recovery, located in Morehead, KY, specializes in treating adults with substance use disorders alongside serious mental health issues, as well as addressing emotional challenges in children. The center offers a range of services, including intensive outpatient programming, long-term residential care, and standard outpatient treatment. Their therapeutic methods include 12-step facilitation, anger management, and short-term interventions. Revived Recovery provides customized programs for adult men and also caters to survivors of intimate partner violence, domestic violence, and sexual abuse. Primarily focused on male clients, the center is dedicated to delivering high-quality care and support for individuals in need of thorough rehabilitation services.

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Revived Recovery Transitional Care, situated in Morehead, KY, provides individualized substance abuse treatment coupled with transitional housing specifically for adult males. The center emphasizes a range of therapeutic practices, including 12-step support, anger management strategies, and focused intervention approaches. Offering short-term residential care, the facility maintains a nurturing atmosphere. With a specialization in serving adult and young adult men, it ensures continuous support and a commitment to quality treatment. For those in search of an all-encompassing recovery program within a well-organized framework, this center presents a tailored methodology for overcoming addiction.

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Nestled in Marion, NC, RHA Behavioral Health Services delivers thorough care for individuals grappling with substance use disorders and co-occurring mental health challenges. They also address serious emotional disturbances in younger individuals. The facility offers various levels of care, including intensive outpatient and outpatient programs, with medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Specific programs are available for adolescents, survivors of intimate partner violence, domestic abuse, and sexual assault. Utilizing personalized therapeutic methods such as 12-step facilitation, anger management techniques, and brief intervention strategies, RHA Behavioral Health Services supports both men and women across all age demographics. Select RHA Behavioral Health Services for skilled guidance and assistance throughout your journey to wellness.

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Whiteville, NC

Situated in Whiteville, NC, RHA Health Services delivers extensive treatment for substance use disorders among adults and young adults who also face significant mental health challenges or emotional issues. The center features a variety of programs, including intensive outpatient services, outpatient day programs, and partial hospitalization options. By employing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, RHA Health Services serves both men and women, as well as those who have dealt with intimate partner violence. With dedicated programs designed for various age groups and genders, the center is committed to providing customized care and support to all individuals on their path to recovery.

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Bladenboro, NC

Situated in Bladenboro, NC, RHA Health Services provides a wide range of treatment options for substance use disorders and specialized support for individuals dealing with co-occurring mental health issues. The facility offers intensive outpatient programs, outpatient day treatment, and partial hospitalization settings specifically designed for both adults and young adults. Emphasizing methods such as 12-step facilitation, cognitive behavioral therapy, and motivational incentives, RHA Health Services delivers tailored care to meet the unique needs of each person. The center also features specific programs catering to adult men, adult women, and those affected by domestic violence. Its gender-sensitive approach and dedication to delivering high-quality care position it as a vital asset for individuals in search of effective rehabilitation solutions.

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Bridgewater, NJ

Richard Hall CHWC in Bridgewater, NJ, provides specialized care for adults and children struggling with substance use and co-occurring mental health issues through intensive outpatient and outpatient programs. Their services include 12-step facilitation, anger management techniques, and brief intervention strategies. The center has a particular expertise in supporting individuals who have experienced trauma and those managing dual diagnoses. They offer customized treatment plans for adults and young adults, respecting all gender identities. Richard Hall CHWC is dedicated to delivering high-quality, personalized rehabilitation services for a holistic recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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