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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Right Choice Recovery

Right Choice Recovery, located in Dayton, NJ, provides a thorough approach to treating adults dealing with substance use issues alongside mental health disorders, as well as children facing significant emotional challenges. The center features a range of treatment modalities including intensive outpatient programs, outpatient services, and day treatment. It also offers tailored programs for active duty military personnel, teenagers, and men. The center employs various strategies such as 12-step facilitation, anger management, and brief intervention techniques. By serving both adults and children, with services designed for male and female clients alike, this facility is committed to delivering personalized care and assistance for individuals on their path to overcoming addiction and addressing mental health issues.

Right Turn IMPACT Treatment Center

Nestled in Sykesville, MD, Right Turn IMPACT Treatment Center is a distinguished institution providing a complete spectrum of addiction rehabilitation. Their offerings encompass crucial services like detoxification, comprehensive substance abuse therapy, and supportive transitional and sober living arrangements. The center supports adults and young adults across all gender identities, employing diverse treatment methodologies including intensive outpatient, extended residential stays, and standard outpatient care. Employing proven strategies such as 12-step facilitation, cognitive behavioral therapy, and brief intervention, Right Turn IMPACT Treatment Center customizes each recovery journey to the unique requirements of every client. They also feature specialized support for active-duty military members, adult men, and adult women, underscoring their commitment to delivering exceptional care and guiding individuals toward lasting sobriety.

Rimrock Trails Treatment Services

Situated in Prineville, OR, Rimrock Trails Treatment Services provides a range of extensive rehabilitation programs, including long-term residential care, short-term stays, and 24-hour residential support for those facing challenges with substance abuse and concurrent mental health disorders. The center is equipped to offer specialized treatment for youth and individuals who have encountered trauma, such as domestic violence and sexual assault, fostering a supportive environment for recovery. By employing proven methods like 12-step programs, anger management techniques, and brief intervention strategies, the facility adapts its approach to address the diverse needs of each individual. Rimrock Trails Treatment Services accepts clients of all genders looking for targeted, high-quality rehabilitation assistance.

Rise Luxury Rehab LLC

Situated in Malibu, California, Rise Luxury Rehab LLC delivers exceptional detox and substance misuse therapy. The center specializes in long-term residential care, residential detox, and around-the-clock support. Emphasizing 12-step programs, anger management techniques, and short intervention strategies, it serves adult men and women, particularly those affected by intimate partner or domestic violence. With dedicated programs for both adults and young adults, clients are provided with personalized treatment plans and superior care at Rise Luxury Rehab LLC.

Rising Phoenix Wellness Services

Rising Phoenix Wellness Services, situated in Scottsdale, AZ, provides thorough substance abuse recovery services for adults and younger adults. They expertly address co-occurring mental health conditions and offer intensive outpatient, day treatment outpatient, and partial hospitalization programs. Their approach incorporates anger management, brief intervention, and cognitive behavioral therapy, serving both male and female patients, including those in active military service. This center is recognized for its dedication to high-quality treatment and personalized recovery paths, positioning it as a leading option for individuals pursuing effective and encouraging rehabilitation.

Right Path Recovery

Situated in Columbus, OH, Right Path Recovery delivers a thorough spectrum of addiction treatment solutions customized for each person. This center features intensive outpatient, extended residential stays, and outpatient options for adults and emerging adults. By emphasizing anger management, cognitive behavioral therapy, and community reinforcement with incentives, the center provides excellent support for both men and women. Right Path Recovery also has distinct programs for active military members. Whether clients require temporary lodging or a drug-free setting, this facility addresses the specific requirements of every individual, positioning it as a prime option for those in search of impactful recovery services.

River Hills Community Health Center

Situated in Ottumwa, IA, the River Hills Community Health Center provides targeted outpatient services for adults grappling with substance use disorders. The center employs a personalized methodology for treatment, particularly addressing the challenges of concurrent substance abuse and severe mental health issues or emotional challenges. Offering a variety of services such as counseling for substance use disorders and telehealth therapy options, this facility serves both men and women who are in search of effective treatment. Their offerings include outpatient services for methadone/buprenorphine or naltrexone, alongside standard outpatient care. If you or someone close to you needs customized and holistic support for addiction, this center is committed to offering expert care for adults.

River Parishes Treatment Center

River Parishes Treatment Center in La Place, LA, provides comprehensive outpatient services for adults battling substance use disorders, particularly those experiencing co-occurring mental health challenges. They also support children with significant emotional difficulties. Their treatment options include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Therapeutic interventions such as anger management, brief intervention strategies, and cognitive behavioral therapy are integrated into treatment plans. The center has developed specialized programs tailored for adolescents, adult men, and adult women, emphasizing a personalized approach to recovery. Catering to adults and seniors across genders, River Parishes Treatment Center is dedicated to delivering high-quality, individualized support for long-term healing.

Ringer Centers Inc
Greensboro, NC

Ringer Centers Inc in Greensboro, NC, specializes in comprehensive addiction recovery. They offer tailored programs including intensive outpatient, standard outpatient, and outpatient detoxification. Their therapeutic approach incorporates methods like 12-step facilitation, brief intervention, and cognitive-behavioral therapy. Ringer Centers Inc serves adult men and women, including those with trauma histories, and also provides services for children and adolescents, with distinct options for male and female patients. Their commitment to excellence and diverse treatment plans guides individuals toward lasting sobriety.

Rivendell Behavioral Health Services

Situated in Bowling Green, KY, Rivendell Behavioral Health Services provides extensive rehabilitation for both adults and children dealing with addiction. This facility offers inpatient detoxification and treatment programs specifically designed for individuals facing concurrent substance use and mental health issues. With dedicated programs for adolescents, as well as adult men and women, Rivendell employs proven methodologies such as 12-step support, anger management techniques, and brief intervention strategies to assist in the recovery process. The center operates around-the-clock, ensuring a secure and nurturing environment for those striving to overcome their substance use challenges. Rivendell Behavioral Health Services focuses on delivering high-quality care tailored for male and female patients, establishing itself as a vital resource for effective addiction recovery.

River Hills Community Health Center

River Hills Community Health Center, located in Oskaloosa, IA, specializes in providing outpatient treatment tailored for adults dealing with substance use issues and associated mental health disorders. This facility emphasizes personalized care, offering counseling for substance use disorders and access to telemedicine therapy. Catering to both men and women, River Hills focuses on a unique approach to recovery. Among its services are outpatient treatments using methadone, buprenorphine, or naltrexone. The center is recognized for its exceptional care and dedication to assisting individuals on the path to recovery and improved mental health.

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Rigel Recovery Services, situated in Fremont, OH, provides expert treatment for adults and young adults dealing with substance use disorders alongside significant mental health challenges. The center features both intensive outpatient and regular outpatient programs, as well as options for methadone and buprenorphine treatments. Emphasizing methods such as anger management, cognitive behavioral therapy, and motivational incentives, they customize the treatment experience to meet the specific needs of each individual. The center has specialized programs for adult men, women, and individuals who have faced sexual abuse. With a commitment to offering compassionate and high-quality care, Rigel Recovery Services stands out as a leading option for those pursuing rehabilitation.

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Situated in Tiffin, OH, Rigel Recovery Services delivers a wide range of addiction treatment options for both adults and young adults. The center specializes in detoxification and treatment for substance use disorders, along with tailored support for individuals facing simultaneous substance use issues and significant mental health challenges in adults or serious emotional issues in children. Employing methods such as cognitive behavioral therapy and contingency management, the center features intensive outpatient and outpatient programs, which include detox services. Rigel Recovery Services serves both men and women, as well as individuals who have experienced trauma from sexual abuse. With an emphasis on personalized care and scientifically supported practices, this facility fosters a nurturing atmosphere for those on the path to recovery.

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Rigel Recovery Services, located in Akron, OH, provides a wide array of treatment options for adults and young adults dealing with substance use issues. The facility addresses the needs of those with dual diagnoses, targeting both substance use disorders and significant mental health challenges. Emphasizing intensive outpatient programs, day treatment, and partial hospitalization, the center employs proven methodologies including anger management, cognitive behavioral therapy, and motivational incentives. Customized programs designed for both men and women promote personalized care. Rigel Recovery Services is dedicated to offering effective, gender-sensitive treatment to foster enduring recovery for its clients.

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In Norwalk, OH, Rigel Recovery Services delivers thorough addiction treatment and expert support for individuals facing dual diagnoses, addressing both substance use issues and significant mental health challenges in adults, or emotional difficulties in youth. The center provides various treatment options, including intensive outpatient care and outpatient methadone/buprenorphine services, employing proven methods like anger management, cognitive behavioral therapy, and motivational incentives. Specialized programs are available for adult men, women, and those who have experienced sexual abuse, acknowledging specific requirements. This facility is dedicated to offering high-quality, compassionate care to adults and young adults of any gender, fostering an environment conducive to long-term healing and recovery.

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Billings, MT

Rimrock, situated in Billings, MT, delivers extensive addiction recovery services for both adults and youth. The facility specializes in detoxification, treatment for substance use disorders, and supports individuals facing both substance abuse and significant mental health challenges. Offering a variety of treatment options, including intensive outpatient, long-term residential, and outpatient programs, Rimrock is equipped to meet various patient needs. Its customized strategies, which encompass 12-step facilitation, anger management, and brief therapeutic interventions, focus on providing personalized care. Furthermore, Rimrock features unique programs for active duty military personnel, adult men, and women, as well as gender-specific treatment approaches, showcasing its dedication to inclusive and high-quality care.

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Situated in Espanola, NM, the Rio Arriba County Department of offers extensive outpatient treatment for substance use disorders, assisting both adults and children who face concurrent severe mental health challenges. The center features targeted programs specifically for adult individuals and pregnant/postpartum women, accommodating clients of all genders. By employing evidence-based methodologies, such as cognitive behavioral therapy and anger management, this facility provides outpatient treatment options with methadone, buprenorphine, or naltrexone. Committed to delivering high-quality care and personalized treatment strategies, this center is devoted to aiding adults and seniors on their path to recovery.

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Rio Rancho Health Services, situated in Rio Rancho, NM, provides comprehensive outpatient support for individuals grappling with substance use. Their services encompass detoxification, treatment, and counseling. The center is particularly adept at assisting active duty military members, as well as adult men and women. They offer customized programs for both adults and young adults, emphasizing personalized care plans. Rio Rancho Health Services is committed to delivering excellent support and treatment for those on the path to recovery. Through various outpatient options, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, the facility strives to guide clients toward enduring sobriety and improved well-being.

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River City Professional Csl Servs LLC, located in Monroe, LA, specializes in complete care for individuals struggling with addiction and dual diagnoses of significant mental health challenges. The program includes robust intensive outpatient care, general outpatient services, and medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. They utilize approaches like 12-step facilitation, anger management training, and brief intervention, serving a wide age range from children and adolescents to adults and young adults. The center also offers specialized support for teens, adult men, and adult women, providing individualized attention. Their dedication to high-quality treatment and varied therapeutic methods establishes River City Professional Csl Servs LLC as a key provider for effective recovery services.

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River City Rehabilitation Center Inc, located in New Braunfels, TX, provides targeted substance abuse treatment services for both adults and young adults. The center offers various outpatient options, such as methadone, buprenorphine, or naltrexone therapies along with standard outpatient care. Emphasizing tailored treatment plans, they employ proven methods including 12-step programs, brief interventions, and cognitive behavioral techniques. River City Rehabilitation Center is particularly attentive to the needs of adult men and women, offering gender-specific programs that foster a nurturing atmosphere for all clients. If you are seeking effective addiction recovery in a caring environment, this facility is an excellent choice for thorough and individualized support.

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River City Rehabilitation Center Inc. in San Antonio, TX, delivers targeted outpatient services for individuals battling substance use disorders. Their comprehensive approach encompasses various treatment modalities such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient care, and support through 12-step facilitation. Employing strategies like brief intervention and cognitive behavioral therapy, the center supports adults, including young adults, and offers gender-specific programming. River City Rehabilitation Center is dedicated to providing effective and individualized care for adults pursuing recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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