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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Rockland Recovery Treatment Center

Rockland Recovery Treatment Center, located in Braintree, MA, delivers an extensive array of services for those dealing with substance use challenges, along with support for individuals facing co-occurring mental health disorders. The center features multiple program formats, including intensive outpatient, long-term residential, and standard outpatient options, all of which incorporate methodologies like 12-step programs, anger management training, and brief interventions. Additionally, it offers specialized services designed for active duty military personnel, teenagers, and adult men, ensuring that its offerings are suitable for a diverse clientele. Renowned for its commitment to high-quality care and personalized treatment strategies, Rockland Recovery is a reliable choice for anyone on the path to recovery and healing.

Rockland Treatment Center
New Port Richey, FL

At Rockland Treatment Center, situated in New Port Richey, FL, we provide a full spectrum of care for individuals struggling with substance misuse. Our expertise lies in addressing dual diagnoses, which involve addiction combined with significant mental health conditions in adults and profound emotional challenges in young people. We offer diverse treatment modalities, including intensive outpatient, extended residential stays, and standard outpatient services. Rockland employs tailored strategies such as 12-step integration, emotional regulation techniques, and brief counseling. The center features distinct programs designed for adult men and women, individuals affected by intimate partner violence, and those who have endured domestic abuse. Catering to adults and young adults across all gender identities, Rockland Treatment Center is dedicated to offering superior, customized support for those on their journey to recovery.

Roger Williams Medical Center

Roger Williams Medical Center, located in Providence, RI, provides a wide range of services for addiction recovery, encompassing detoxification and treatment for substance use disorders. The center features hospital-based inpatient detox and treatment options, with unique programs designed specifically for active duty military members and customized services for both adult men and women. Employing evidence-based methods, including brief interventions, relapse prevention strategies, and counseling for substance use disorders, the facility aims to deliver effective care. Catering to both adults and young adults, the center is dedicated to offering individualized, high-quality treatment to help individuals on their journey to recovery from addiction.

Rogers Behavioral Health

Rogers Behavioral Health, situated in Milwaukee, WI, specializes in a wide range of substance use rehabilitation along with targeted care for individuals facing serious mental health challenges concurrently. This facility offers various treatment options, including intensive outpatient programs, outpatient day treatment, and partial hospitalization for both adults and young people. By implementing proven methods like 12-step facilitation, cognitive behavioral therapy, and the Matrix Model, the center serves a variety of groups, including military personnel, teenagers, and adult males. Emphasizing personalized treatment plans, Rogers Behavioral Health aims to provide high-quality care to all clients on their journey to recovery and wellness.

Rome Memorial Hospital

Rome Memorial Hospital in Rome, NY, provides extensive substance abuse services for individuals of all ages struggling with co-occurring mental health disorders. Their offerings encompass intensive outpatient programs, standard outpatient services, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The facility is adept in techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. Catering to specific needs, they have distinct programs for teenagers, adult men, and adult women, ensuring personalized support for diverse age groups and genders. Clients will experience effective, scientifically-backed treatment designed to meet their specific challenges within a safe and encouraging setting.

Rogers Behavioral Health

Rogers Behavioral Health, situated in Madison, WI, specializes in treating substance use issues and co-occurring disorders for both adults and children. The center offers a variety of programs including intensive outpatient, outpatient, and day treatment. Emphasizing methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the facility customizes its treatment to meet each individual's specific requirements. There are specialized programs available for adolescents and individuals dealing with combined mental health challenges and substance use disorders. Catering to both men and women, Rogers Behavioral Health is committed to providing high-quality, compassionate care, making it an excellent option for those in search of thorough rehabilitation services in the Madison region.

Rogers Behavioral Health

Situated in Kenosha, Wisconsin, Rogers Behavioral Health delivers exceptional rehabilitation services for those facing challenges related to substance abuse and concurrent mental health issues. The center features various programs, including intensive outpatient care, outpatient day treatment, and partial hospitalization, designed for both adults and children/adolescents. Catered to specific groups such as active duty service members, men, and women, Rogers Behavioral Health utilizes proven methods, including 12-step support, cognitive behavioral therapy, and the Matrix Model. This facility is committed to offering holistic care aimed at helping patients attain long-lasting recovery and improved mental health.

Rogers Behavioral Health

Rogers Behavioral Health in Appleton, WI, provides extensive care for addiction in both young people and adults. They focus on individuals facing co-occurring substance use and mental health challenges, offering day treatment, intensive outpatient, and outpatient services. Utilizing proven methods such as motivational interviewing and cognitive behavioral therapy, the center supports those with a history of trauma. Their specialized programs for teens and clients with dual diagnoses highlight a commitment to personalized recovery for all genders.

Rogers Behavioral Health

Rogers Behavioral Health, located in Oconomowoc, WI, specializes in providing focused care for both substance abuse issues and concurrent mental health challenges in both adults and children. Their range of services encompasses intensive outpatient, standard outpatient, and day treatment programs. With a foundation in evidence-based practices, such as 12-step facilitation, cognitive behavioral therapy, and the Matrix Model, the center offers customized support for individuals, including men and women who have faced intimate partner or domestic violence. Targeting young adults with a tailored gender-specific framework, Rogers Behavioral Health is dedicated to delivering top-notch, personalized treatment for those on the path to recovery.

Rockbridge Area Community Servs Board

Rockbridge Area Community Servs Board, located in Lexington, VA, provides outpatient treatment for substance use, emphasizing Anger Management, Cognitive Behavioral Therapy, and Brief Intervention techniques. This center features targeted programs for youth, adult men, and adult women, accommodating a diverse range of clients including children and teenagers. With options for outpatient treatment using methadone, buprenorphine, or naltrexone, the facility guarantees thorough support for individuals facing addiction challenges. The center's commitment to quality care and customized programs establishes it as an essential support system for those aiming to tackle substance use challenges in a nurturing setting.

Rockville Ctr Drug and Alcohol Abuse

Rockville Ctr Drug and Alcohol Abuse, located in Rockville Centre, NY, provides a wide range of treatment options for substance use disorders. The center specializes in various outpatient services, including methadone/buprenorphine and naltrexone therapies, alongside standard outpatient programs. It emphasizes evidence-based practices like 12-step facilitation, anger management strategies, and brief intervention methods. Catering to diverse populations, including adult men, adult women, and individuals facing both mental health and substance abuse challenges, this center guarantees gender-sensitive care for clients of all ages—adults, children, and adolescents alike. With a commitment to personalized care and effective treatment strategies, Rockville Ctr Drug and Alcohol Abuse stands out as a reliable resource for those in need of rehabilitation from addiction.

Rocky Boy Health Center

Situated in Box Elder, MT, Rocky Boy Health Center provides extensive substance use disorder services for adults and older adults. Emphasizing ambulatory care, this institution features distinct offerings including outpatient medication-assisted treatment (methadone, buprenorphine, or naltrexone) and general outpatient services. Recovery is fostered through scientifically supported methods such as 12-step facilitation, anger management techniques, and brief intervention strategies. Specifically addressing the needs of individuals involved with the criminal justice system, Rocky Boy Health Center delivers individualized treatment plans. The center accommodates both male and female patients, underscoring its commitment to high-quality, individualized assistance for those pursuing freedom from addiction.

Root Center for Advanced Recovery

Root Center for Advanced Recovery, located in Bristol, CT, delivers extensive treatment for substance use disorders and addresses the needs of individuals facing dual mental health challenges. This center offers a range of options including intensive outpatient care, standard outpatient services, and day treatment programs. Their approach emphasizes 12-step guidance, cognitive behavioral techniques, and short-term interventions. Customized programs are designed for adult men and women, as well as individuals impacted by intimate partner violence. Catering to adults and young adults across all gender identities, the center prioritizes providing high-quality support and a nurturing atmosphere for those on their path to recovery from addiction.

Root Center for Advanced Recovery

Root Center for Advanced Recovery is situated in Manchester, CT, and delivers extensive treatment for adults facing substance use challenges alongside severe mental health disorders, as well as for children dealing with significant emotional issues. The center offers a range of services, including intensive outpatient programs, outpatient care, and medication-assisted therapies with methadone, buprenorphine, or naltrexone. Emphasizing a blend of 12-step strategies, brief interventions, and cognitive behavioral therapy, it is designed to support adult men, women, and teenagers. Their specialized initiatives focus on the unique needs of various groups, providing customized support for both adults and youth. Root Center for Advanced Recovery is recognized for its high-quality care and personalized treatment strategies for addiction.

Root Center for Advanced Recovery

Situated in Willimantic, CT, the Root Center for Advanced Recovery specializes in addressing substance use disorders alongside mental health issues. The center offers a variety of treatment options, including intensive outpatient services, outpatient programs, and medication-assisted treatments such as methadone, buprenorphine, or naltrexone. Emphasizing therapeutic methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy, the facility serves adolescents, men, and women of all ages. Committed to providing exceptional and holistic care, this center aims to support individuals of all genders on their journey to recovery.

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Nestled in Valley Cottage, NY, Rockland Medication Assisted Treatment delivers targeted outpatient care for individuals dealing with substance use issues alongside mental health challenges. The facility offers outpatient treatment options including methadone, buprenorphine, and naltrexone, complemented by conventional outpatient therapy. Emphasizing anger management, brief intervention, and cognitive behavioral therapy, this center addresses the needs of adult men and women, including those with dual diagnoses. Catering to diverse populations such as adults, seniors, and young adults across all gender identities, the center's personalized approach guarantees all-encompassing support for those pursuing effective and empathetic rehabilitation solutions.

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Rockland Outreach Center, situated in Blauvelt, NY, delivers expert recovery programs for individuals struggling with substance dependence and co-occurring psychiatric conditions. Their offerings include robust intensive outpatient, structured day treatment, and partial hospitalization services. Addressing critical areas like anger control, cognitive restructuring, and short-term therapeutic approaches, they support adults, seniors, and young people, with distinct tracks for military personnel, adult males, and mixed-gender groups. Rockland Outreach Center is dedicated to providing high-caliber support for those pursuing all-encompassing and individualized recovery from addiction and mental health issues.

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Situated in Blauvelt, NY, the Rockland Outreach Center provides extensive treatment for substance use disorders and specialized assistance for individuals facing both substance use and mental health issues, catering to both adults and children. The center offers a variety of treatment options, including intensive outpatient programs, outpatient services, and daytime treatment. Utilizing evidence-based methodologies such as anger management, cognitive behavioral therapy, and motivational interviewing, the facility also features customized programs designed specifically for active duty military personnel, adolescents, and adult males. Rockland Outreach Center is committed to delivering high-quality care and support for individuals of all genders seeking to achieve recovery and comprehensive wellness.

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Rogers Behavioral Health in Milwaukee, WI, delivers targeted therapies for addiction and dual diagnoses in individuals of all ages. This facility provides comprehensive care through various outpatient and day programs, customizing treatment intensity to each person's requirements. Employing proven methods such as cognitive behavioral therapy and the Matrix Model, the center emphasizes complete wellness. Dedicated services are available for active military personnel, teenagers, and adult men, offering specialized assistance. Catering to both male and female patients, the center is committed to offering exceptional, all-encompassing care to support sustained sobriety.

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Situated in New London, CT, the Root Center for Advanced Recovery specializes in treating adults who struggle with substance use and concurrent mental health issues, as well as children dealing with significant emotional difficulties. The center provides thorough care via intensive outpatient and outpatient programs, employing proven methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. Customized treatment options for teenagers, adult men, and women guarantee that each patient receives individualized attention. Committed to delivering high-quality care with empathy, the center accommodates both male and female clients, creating a secure and nurturing space for their recovery journey.

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Root Center for Advanced Recovery, situated in Middletown, CT, specializes in holistic treatment for substance use issues in both adults and children facing concurrent mental health challenges. The facility offers a range of services, including intensive outpatient programs, outpatient care, and targeted treatments with methadone, buprenorphine, or naltrexone. Employing research-supported methods such as 12-step programs, cognitive behavioral therapy, and brief intervention strategies, the center serves adult men and women, as well as teens. With tailored programs designed for various demographics and needs, Root Center for Advanced Recovery prioritizes personalized care and effective support, focusing on achieving sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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