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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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SaVida Health
Newport, VT

SaVida Health located in Newport, VT, specializes in outpatient treatment for adults and young adults dealing with substance use issues alongside significant mental health challenges or emotional difficulties. The center administers treatments such as methadone, buprenorphine, and naltrexone in conjunction with standard outpatient services. Their methods incorporate techniques like anger management, brief interventions, and cognitive behavioral therapy. SaVida Health serves a diverse population, including men and women who have faced trauma. By offering specialized programs designed for various genders and age categories, this center guarantees customized support and assistance for individuals pursuing in-depth rehabilitation solutions.

SaVida Health
Morrisville, VT

SaVida Health located in Morrisville, VT, provides outpatient services for adults facing substance use challenges and co-occurring mental health disorders, as well as emotional issues in children. The center offers medications such as methadone, buprenorphine, and naltrexone, in conjunction with standard outpatient therapies. Emphasizing approaches like anger management, brief intervention, and cognitive behavioral therapy, the facility supports both men and women, including those who have dealt with trauma. By accommodating adults and young adults of all backgrounds, SaVida Health ensures a high standard of care through customized programs that address the unique needs of each individual, making it an excellent option for those in need of effective rehabilitation support.

SaVida Health
Springfield, VT

SaVida Health, situated in Springfield, VT, delivers thorough outpatient care for individuals struggling with substance use disorders. The center caters to adults and young adults with distinct programs designed for men, women, and those who have undergone trauma. Their approach emphasizes personalized treatment, incorporating techniques such as anger management, brief intervention, and cognitive behavioral therapy. SaVida Health offers outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, in addition to general outpatient services. The facility is committed to providing a nurturing setting and high-quality support for all its male and female clients as they pursue lasting sobriety.

SaVida Health
Saint Johnsbury, VT

SaVida Health in Saint Johnsbury, VT, delivers outpatient services for adults battling substance use disorders, particularly those also facing significant mental health challenges. The facility is equipped to support individuals with emotional difficulties and past trauma. Services encompass outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone), as well as specialized interventions like anger management, brief therapeutic approaches, and cognitive behavioral therapy. SaVida Health provides gender-specific programming for adult men and women. Prioritizing high-quality, personalized care, SaVida Health assists adults and young adults in their journey toward recovery.

SRR Treatment Solutions

SRR Treatment Solutions, located in Columbia, MD, delivers thorough detox and addiction treatment programs for adults and younger individuals. They offer specialized intensive outpatient, standard outpatient, and outpatient detox services designed to meet each person's unique requirements. Through techniques like motivational interviewing, relapse prevention planning, and individual counseling for substance use disorders, the facility prioritizes a customized path to recovery. SRR Treatment Solutions provides distinct care for male and female clients, fostering a welcoming and supportive setting. For excellent addiction care centered on personal progress, this center is distinguished by its dedication to guiding clients toward sustained recovery.

SaVida Health
Colchester, VT

SaVida Health, located in Colchester, VT, specializes in outpatient treatment for substance use disorders targeting both adults and young adults, including individuals facing severe mental health challenges. The facility offers treatments involving methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Emphasizing techniques such as anger management, short intervention strategies, and cognitive behavioral therapy, the center serves adult clients, including those who have a history of trauma. SaVida Health is dedicated to providing high-quality care in a nurturing setting for those in need of focused therapeutic support.

SaVida Health
Dover, DE

At SaVida Health, located in Dover, DE, we provide extensive care for substance use disorders via our outpatient services. These include medication-assisted treatment with methadone, buprenorphine, or naltrexone, as well as standard outpatient therapy. Our expertise lies in developing effective relapse prevention plans, and we offer remote therapy options for greater accessibility. SaVida Health has specific programs designed for active military personnel, adult men, and adult women, addressing the varied needs of our clientele. We welcome adults and young adults of all gender identities, offering personalized support and treatment plans to meet each individual's distinct requirements. SaVida Health in Dover, DE is committed to delivering exceptional and results-driven addiction treatment.

SSM Health Treatment and Recovery

SSM Health Treatment and Recovery, situated in Wentzville, MO, delivers a complete spectrum of substance use interventions for adults and young adults. This facility excels in addressing dual diagnoses, managing co-occurring substance use disorders and significant mental health challenges within a nurturing setting. Their array of services, encompassing intensive outpatient care and outpatient methadone/buprenorphine services, allows for personalized treatment plans designed for each individual's requirements. Utilizing scientifically validated methods like cognitive behavioral therapy and anger management, the center prioritizes effective recovery results. SSM Health Treatment and Recovery further extends its offerings with tailored programs for individuals managing both pain and substance use disorders, serving both men and women who are pursuing excellent care and assistance on their path to healing.

SW Arkansas Counseling MHC Inc

SW Arkansas Counseling MHC Inc in Texarkana, AR, delivers focused treatment for substance use and co-occurring mental health disorders for both adults and children. This center provides various programs including intensive outpatient, outpatient, and daytime treatment, all customized to meet each individual's requirements. Emphasizing 12-step support, anger management techniques, and short intervention strategies, the facility guarantees comprehensive assistance. Specialized programs are available for adolescents, as well as adult men and women, catering to their distinct needs. Serving clients of all genders, this center provides exceptional, gender-sensitive treatment. Whether individuals require help with substance abuse or mental health challenges, this facility offers effective, tailored care suitable for all ages and demographics.

SaVida Health
Vergennes, VT

SaVida Health, located in Vergennes, VT, offers outpatient treatment for substance use issues targeting both adults and young adults, with a particular emphasis on co-occurring disorders and severe mental health challenges. The center provides outpatient options including methadone/buprenorphine and naltrexone therapies, employing techniques rooted in evidence-based methods like anger management, brief intervention, and cognitive behavioral therapy. They feature tailored programs designed for adult men and women, as well as individuals with trauma backgrounds. By concentrating on adult and young adult populations, SaVida Health is committed to delivering high-quality care and customized treatment strategies to foster recovery and overall wellness.

SaVida Health
Worcester, MA

SaVida Health, located in Worcester, MA, specializes in outpatient treatment for substance use, prioritizing high-quality care and effective methodologies. The center offers outpatient services for methadone/buprenorphine or naltrexone, along with regular outpatient treatment, and tailored programs for men, women, and individuals who have faced trauma. Their offerings encompass anger management, brief interventions, and cognitive behavioral therapy. SaVida Health serves adults and young adults across all genders, providing a comprehensive and personalized approach to recovery from addiction. If you are looking for research-supported treatment in a nurturing setting, this center is committed to supporting you on your path to achieving long-term sobriety.

SaVida Health
Newark, DE

SaVida Health, located in Newark, DE, provides outpatient care for adults and adolescents struggling with substance use and co-occurring mental health challenges. Dedicated services are available for military personnel, men, and women. Treatment modalities include outpatient methadone, buprenorphine, or naltrexone. Employing proven strategies such as brief interventions, motivational incentives, and relapse prevention techniques, SaVida Health delivers thorough support. Prioritizing excellence and personalized recovery plans, SaVida Health offers distinct care paths for men and women aiming for sobriety.

SaVida Health
Bennington, VT

SaVida Health in Bennington, VT, is dedicated to providing extensive outpatient care for adults grappling with substance use disorders. Recognizing the profound impact of trauma, the center features tailored programs designed to address these co-occurring challenges. Their therapeutic approach heavily incorporates cognitive behavioral therapy, anger management techniques, and concise, effective interventions, ensuring each individual receives a personalized recovery plan. SaVida Health extends its services to both adults and young adults, offering outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone within a supportive setting. The commitment at SaVida Health is to deliver exceptional care, equipping clients with the tools and encouragement needed to achieve lasting sobriety.

START Treatment and Recovery Centers

START Treatment and Recovery Centers, located in New York, NY, delivers focused outpatient programs for substance use treatment aimed at both adults and young adults. The center employs proven strategies, including brief interventions, cognitive behavioral therapy, and motivational interviewing, to ensure customized support for individuals on the path to recovery. With an emphasis on inclusivity, START features dedicated programs for adult men and women, as well as clients who have faced incidents of intimate partner or domestic violence. Moreover, the center offers outpatient treatment options using methadone, buprenorphine, or naltrexone, fostering a well-rounded and supportive atmosphere for clients striving for sobriety.

SaVida Health
Blacksburg, VA

SaVida Health in Blacksburg, VA, delivers accessible outpatient programs designed for adults and adolescents confronting the dual challenges of substance use and significant mental health conditions. Their treatment spectrum encompasses medication-assisted options like methadone, buprenorphine, or naltrexone, alongside comprehensive outpatient services. Therapies offered at the center include strategies for managing anger, brief interventions, and cognitive behavioral techniques. SaVida Health is committed to tailoring treatment plans to each individual, serving both men and women. For those in search of effective and personalized addiction recovery support, SaVida Health presents a compelling option.

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Fall River, MA

SSTAR, situated in Fall River, MA, specializes in a variety of evidence-supported therapies for individuals dealing with substance use issues and related mental health challenges, catering to both adults and children. The facility offers intensive outpatient, outpatient, and day treatment services, utilizing methods such as 12-step support, anger management, and brief intervention techniques. Additionally, it features tailored programs for those who have faced intimate partner violence, domestic abuse, sexual trauma, and other forms of adversity. Serving individuals of all genders, SSTAR prioritizes customized care and guidance to facilitate meaningful recovery. Known for its commitment to quality and all-encompassing services, this center is recognized as a reliable option for those in pursuit of effective rehabilitation solutions.

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Fall River, MA

Situated in Fall River, MA, SSTAR is a distinguished rehabilitation facility that provides a wide range of services for both adults and young adults facing challenges related to substance use and concurrent mental health conditions. The center offers residential detox services and round-the-clock residential treatment programs, employing effective methods including 12-step facilitation, brief interventions, and cognitive behavioral therapy. SSTAR serves a diverse clientele, including adult men, women, and those with co-occurring disorders, ensuring tailored support for every individual. Emphasizing high-quality and personalized care, this center is dedicated to assisting clients in their journey toward sustainable recovery.

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Fall River, MA

SSTAR in Fall River, MA, provides extensive addiction care for individuals and adolescents grappling with substance abuse and psychological well-being issues. The facility offers diverse treatment options, including inpatient detox, round-the-clock residential stays, and brief residential stays. SSTAR customizes its methods for men, women, and those with dual diagnoses, ensuring personalized support. Employing proven therapeutic strategies like 12-step support, cognitive behavioral therapy, and concise counseling, the center delivers excellent treatment for all clients pursuing sobriety.

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Orlando, FL

Situated in Orlando, Florida, STEPS Inc delivers extensive treatment for substance use disorders and targeted assistance for those facing significant mental health issues simultaneously. The center presents various options including intensive outpatient, outpatient, and daytime therapies, employing proven methods such as 12-step programs, anger management, and focused interventions. STEPS Inc serves both adult men and women, including active duty military members. With customized programs designed for both adult and young adult participants of any gender, the facility prioritizes effective care and support for those on the journey to recovery from addiction and mental health struggles.

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Cocoa, FL

STEPS Inc, located in Cocoa, FL, specializes in comprehensive treatment for substance use disorders and offers targeted support for individuals facing serious mental health challenges or emotional issues in children. The center provides a range of treatment options, including intensive outpatient, outpatient, and day programs. Emphasizing 12-step strategies, anger management techniques, and brief intervention methods, STEPS Inc customizes its services to address the unique needs of each client. They feature specialized programs for active duty service members as well as separated options for men and women. This facility serves both adults and young adults of any gender, committing to high-quality care and evidence-based methodologies to aid clients in their recovery journey.

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Apopka, FL

STEPS Inc in Apopka, Florida, is a dedicated facility providing extensive recovery support for adult women, older adults, and younger individuals facing challenges with addiction and coexisting severe mental health issues. The center offers structured programs including intensive outpatient care, extended residential stays, and general outpatient services, employing methods such as 12-step guidance, emotional regulation techniques, and brief counseling strategies. STEPS Inc has particular expertise in assisting adult women and those who have endured intimate partner abuse, domestic violence, or sexual trauma. Committed to high standards of care and individualized therapeutic pathways, the facility is devoted to guiding individuals toward lasting healing.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)