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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Sage Neuroscience Center

Sage Neuroscience Center in Albuquerque, NM, delivers a complete suite of rehabilitative programs designed for your unique situation. They offer detox services, address substance abuse, and provide focused support for individuals facing both addiction and significant mental health challenges. Treatment options include robust outpatient programs and a day treatment setting. Their methods are grounded in proven techniques like cognitive behavioral therapy and anger resolution. Sage Neuroscience Center also features dedicated programs for adult men and women, and those affected by intimate partner or domestic violence. Serving all age groups from children to adults, they provide gender-tailored care for both men and women. You can anticipate caring and successful support at this location.

Sage Recovery and Wellness Center

Sage Recovery and Wellness Center, located in Austin, TX, presents a variety of thorough addiction recovery programs designed for both adults and minors. The center focuses on dual diagnosis treatment for individuals facing both substance use and mental health challenges. Offering intensive outpatient, outpatient, and standard outpatient services, the facility employs customized methods that feature 12-step support, anger management strategies, and brief intervention methods. With dedicated programs aimed at teenagers and young adults, Sage Recovery and Wellness Center addresses the needs of a wide array of age groups. The center prioritizes individualized care, welcoming clients of all genders and promoting a nurturing atmosphere for those on their path to recovery.

Saint Annes Home
Chicago, IL

Saint Annes Home, situated in Chicago, IL, provides extended residential support for adult women undergoing substance use recovery within a secure and nurturing setting. The establishment focuses on transitional living and halfway house programs, serving individuals healing from intimate partner violence, domestic abuse, and sexual assault. Employing proven methods such as 12-step facilitation and contingency management, the center delivers thorough care for both young adults and adults. Dedicated to equipping female clients for successful recovery, Saint Annes Home guarantees excellent treatment via tailored plans and empathetic assistance.

Saint Barnabas Hospital

Saint Barnabas Hospital, located in the Bronx, NY, provides outpatient treatment for substance use aimed at both adults and children facing concurrent mental health issues. Their offerings include 12-step programs, strategies for managing anger, and short-term intervention techniques. This center caters specifically to adult men and women, including those who have been victims of intimate partner violence. With a commitment to serving both male and female adults and young adults, Saint Barnabas Hospital prioritizes personalized care to foster recovery and overall wellness. Discover their routine outpatient services tailored to meet the needs of those grappling with substance use disorders and mental health concerns with empathy and professionalism.

Saint Barnabas Hospital

Saint Barnabas Hospital in Bronx, NY, delivers extensive substance abuse recovery programs for adults and younger individuals. Their offerings include outpatient options such as detoxification, general addiction counseling, and dedicated support for dual diagnoses of substance use and mental health conditions. Emphasizing strategies like 12-step encouragement, emotional regulation techniques, and concise counseling, the institution customizes care plans. Saint Barnabas Hospital also distinguishes itself with unique services for adult women, individuals affected by HIV/AIDS, and those facing the combined challenges of pain and addiction. Catering to both men and women, the facility is committed to providing excellent care and individualized assistance throughout the recovery process.

Saint Charles Hospital
Port Jefferson, NY

Saint Charles Hospital, located in Port Jefferson, NY, provides extensive treatment options for substance use through its inpatient services and around-the-clock care. The center is focused on methods such as 12-step programming, brief interventions, and cognitive behavioral therapy. It specifically caters to adult men and women, including those who have faced domestic or intimate partner violence. With services available for both adults and young adults of any gender, Saint Charles Hospital prioritizes customized care that meets individual requirements. If you or someone you know is in search of an effective and supportive approach to addiction recovery, this facility offers various programs designed to assist on the journey to healing.

Saint Charles Hospital
Port Jefferson, NY

Saint Charles Hospital, located in Port Jefferson, NY, delivers extensive care for substance dependence. Their services encompass withdrawal management and broader addiction therapy. Operating with inpatient options and round-the-clock availability, the establishment ensures a secure and nurturing space for healing. Employing methodologies like 12-step integration, cognitive behavioral techniques, and brief counseling, this institution customizes recovery plans. Distinctive support is provided for young people and individuals affected by relationship abuse, domestic violence, and sexual trauma, catering to all age groups. Saint Charles Hospital also offers distinct care for male and female patients, underscoring their commitment to excellent treatment and assistance for those battling addiction.

Saint Charles Hospital
Port Jefferson, NY

Saint Charles Hospital, located in Port Jefferson, NY, offers extensive detox and addiction recovery services. Their inpatient programs feature specialized interventions including 12-step facilitation, brief intervention, and cognitive behavioral therapy. They also provide distinct programs for adult men and women, and for individuals affected by intimate partner or domestic violence. Catering to adults and young adults, Saint Charles Hospital is committed to personalized care within a secure and encouraging setting, establishing it as a reliable option for comprehensive rehabilitation.

Saint Clairsville
McConnelsville, OH

Situated in McConnelsville, OH, Saint Clairsville stands out as a top-tier rehabilitation facility that offers comprehensive outpatient treatment for issues related to substance use, co-occurring conditions, and acute mental health challenges in both adults and children. The center features a variety of targeted programs, such as 12-step approaches, anger management tactics, and short-term interventions. Saint Clairsville is designed to serve active military members, young people, and adult men, with a commitment to providing services that cater to the specific needs of clients of all genders. Emphasizing personalized care and tailored treatment strategies, this center aims to support clients in achieving sustainable recovery and enhancing their overall quality of life.

Saint Clares Behavioral Health

Saint Clares Behavioral Health, located in Boonton, NJ, provides a wide array of addiction treatment options for both adults and young adults, with particular expertise in detoxification, substance use disorders, and co-existing mental health challenges. Emphasizing high-quality care, the center features hospital-based inpatient detox services, intensive outpatient programs, and various evidence-supported methodologies, such as 12-step facilitation and cognitive behavioral therapy. The center also offers specialized programs for those who have faced trauma or have dual diagnoses. Designed to serve both men and women, this facility fosters a nurturing setting conducive to recovery and personal growth.

Saint Cloud VAMC
Saint Cloud, MN

Saint Cloud VAMC, located in Saint Cloud, Minnesota, provides extensive services for adults and young individuals dealing with substance use disorders, as well as concurrent mental health issues. The center features inpatient detoxification, extended treatment, and round-the-clock support, including tailored programs specifically for veterans. It employs methodologies such as 12-step programs, anger management techniques, and brief interventions, accommodating both men and women. Committed to offering high-quality care and personalized treatment strategies, Saint Cloud VAMC aims to assist clients in their recovery journey.

Saint Anthonys
Garrison, NY

Saint Anthonys, situated in Garrison, NY, provides a wide array of addiction rehabilitation services. The facility offers detox services, treatment for substance use, transitional housing, and options for sober living. With various treatment styles such as intensive outpatient care, long-term residential stays, and outpatient programs, Saint Anthonys serves both adults and young adults across all genders. The center focuses on specialties like 12-step support, anger management, and brief interventions, alongside tailored programs for adult men and women, including those who have faced intimate partner or domestic violence. Committed to delivering high-quality, personalized care, the center aims to assist clients on their recovery path.

Saint Christophers Inn

Saint Christophers Inn located in Garrison, NY, delivers thorough addiction rehabilitation services geared towards adult males in a long-term residential environment. This facility includes tailored programs for those who have gone through intimate partner violence and for active military service members. The center adopts a multifaceted approach that features 12-step facilitation, strategies for anger management, and brief intervention methods. By prioritizing transitional housing and sober living arrangements, Saint Christophers Inn is dedicated to guiding clients through the detoxification process and addressing substance use challenges. This initiative is specifically designed for adult men who are looking for a nurturing atmosphere conducive to recovery, emphasizing personalized care and support for each individual’s unique needs.

Saint Christophers Inn Inc

Saint Christophers Inn Inc in Garrison, NY, provides an extensive array of services for substance use treatment specifically designed for adult males. The center focuses on addressing both substance use and significant mental health issues concurrently. Treatment modalities include intensive outpatient services, long-term residential care, and outpatient programs, all of which feature personalized care utilizing methodologies such as 12-step programs and anger management techniques. Specialized programs are available for male adults who have endured intimate partner violence, domestic violence, or sexual trauma. This facility is especially well-equipped for adults and older individuals in need of focused support within a gender-sensitive setting.

Safe Refuge
Long Beach, CA

Safe Refuge, situated in Long Beach, CA, delivers extensive addiction recovery programs for adults and young adults. The center is equipped to provide specialized support for those facing both addiction and significant mental health challenges. Offering a variety of residential options, including long-term, short-term, and 24-hour care, Safe Refuge customizes treatment plans for each client. Their therapeutic methods are grounded in proven techniques like 12-step support, emotional regulation training, and cognitive behavioral strategies. Safe Refuge also features distinct programs designed for active military members, adult men, and women. The facility is committed to high standards of care and provides separate treatment tracks for men and women, fostering a secure and conducive atmosphere for healing.

Saginaw Odyssey House Inc

Saginaw Odyssey House Inc, situated in Saginaw, MI, delivers extensive recovery support for adult women facing challenges with substance abuse and concurrent severe mental health conditions. Their array of services includes long-term residential stays, intensive outpatient care, and standard outpatient treatment. The center is particularly adept at assisting those who have endured intimate partner violence, domestic abuse, and sexual assault. Employing therapeutic methods like anger management, motivational interviewing, and cognitive behavioral therapy, Saginaw Odyssey House Inc serves adults, older adults, and younger adults. This facility offers a secure and nurturing setting strictly for women, ensuring individualized, top-tier care designed to address each resident's specific requirements.

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Saint Paul, MN

Nestled in Saint Paul, MN, Sage Prairie Eagan stands as a dedicated provider of extensive addiction recovery solutions. This establishment features transitional living, halfway house accommodations, and sober living environments, specifically designed for adults contending with both addiction and significant mental health challenges. Employing treatment modalities like inpatient hospital care and robust outpatient programs, Sage Prairie Eagan employs proven therapeutic strategies including 12-step integration, cognitive behavioral therapy, and the Matrix Model. The center boasts specialized offerings for active military members, adult men, and adult women, welcoming individuals across young adult and adult age groups. Sage Prairie Eagan delivers customized support for both male and female individuals in pursuit of effective rehabilitation.

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Saint Croix Behavioral Health Services in New Richmond, WI, is dedicated to providing tailored care for individuals struggling with addiction and accompanying mental health challenges, serving both young people and adults. Their wide array of services encompasses intensive outpatient care, regular outpatient services, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods, including cognitive behavioral therapy and motivational incentives, they foster a path toward lasting recovery. The center features distinct programs designed for teenagers, adult men, and women, addressing specific demographic requirements. Catering to a broad demographic of adults and older adults, regardless of gender, this facility emphasizes personalized treatment plans to ensure sustained wellness and recovery.

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Saint Elizabeth Physicians in Covington, KY, provides extensive substance use disorder treatment for adults and young adults facing co-occurring mental health challenges. Their offerings encompass intensive outpatient services, standard outpatient care, and targeted medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing scientifically validated methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center delivers tailored interventions. Recognizing the unique needs of women, they feature specialized programs for adult women and those who are pregnant or have recently given birth, fostering gender-responsive support. Saint Elizabeth Physicians is committed to high-quality, individualized recovery plans.

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Saint Francis Ministries located in Salina, KS, provides outpatient services for individuals of all ages, including adults, children, adolescents, seniors, and young adults grappling with dual diagnoses involving substance use and mental health challenges. The center emphasizes techniques such as 12-step facilitation, anger management, and concise interventions, while also offering targeted programs for individuals who have faced trauma, sexual abuse, and additional hardships. By customizing treatment plans for both genders, the facility ensures personalized support. Its holistic strategy for tackling addiction and mental health issues makes it an essential option for anyone in search of effective and empathetic rehabilitation assistance.

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Saint Francis Ministries in Salina, KS, provides extensive services for individuals facing substance use challenges, utilizing approaches like intensive outpatient, standard outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their expertise includes guiding patients through 12-step programs, teaching anger management techniques, and employing brief intervention strategies. They offer personalized programs catering to young people, adult men, and adult women, and welcome individuals of any gender and age group, including seniors. Saint Francis Ministries is dedicated to creating custom treatment plans rooted in proven methods, ensuring effective support for anyone pursuing freedom from addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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