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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Salisbury VA Medical Center

Salisbury VA Medical Center, located in Salisbury, NC, delivers extensive rehabilitation support for those overcoming substance use challenges. The center features inpatient detox and treatment, alongside transitional and halfway housing. Tailored services address trauma survivors and veterans, serving adult and young adult men and women. Treatment modalities encompass 12-step facilitation, anger management, and brief intervention. Known for its high standards and personalized plans, the center is a leading option for impactful and empathetic addiction recovery.

Salt Lake Behavioral Health
Salt Lake City, UT

Salt Lake Behavioral Health, located in Salt Lake City, UT, offers a wide range of addiction treatment services designed for both adults and youth. This center features hospital inpatient detoxification along with comprehensive care for substance use disorders, addressing any accompanying mental health issues. Salt Lake Behavioral Health has specialized programs tailored for active military personnel and individuals facing concurrent challenges of pain and substance abuse. By employing therapeutic methods such as 12-step programs, anger management, and brief interventions, the facility underscores its commitment to personalized care for every individual. Focused on delivering high-quality, customized treatment strategies, this center is devoted to guiding clients toward recovery.

SalusCare
Fort Myers, FL

SalusCare, located in Fort Myers, FL, delivers diverse outpatient services addressing addiction and concurrent mental health concerns for individuals of all ages. The facility offers specialized programs including medication-assisted treatment with methadone/buprenorphine and 12-step integration. Through personalized strategies like anger management and crisis intervention, SalusCare supports adolescents, adult women, and those with co-occurring disorders. Serving a broad demographic including seniors, this center is dedicated to providing effective care for those pursuing sobriety and mental wellness.

Salvation Army
Cleveland, OH

The Salvation Army Rehabilitation Center, situated in Cleveland, OH, is dedicated to assisting those on their path to overcoming addiction. They offer a variety of treatment options, including intensive outpatient care, standard outpatient services, and residential detoxification. Employing methods like 12-step facilitation and specialized counseling for substance use disorders, the center develops unique treatment strategies for each person. Their commitment to personalized attention extends to adults and young adults across all genders, ensuring that every individual receives the support necessary for their recovery at the Salvation Army Rehabilitation Center in Cleveland.

Salvation Army Harbor Light Center

In Indianapolis, Indiana, the Salvation Army Harbor Light Center provides a complete spectrum of addiction recovery solutions. Services encompass detoxification, substance abuse therapy, temporary lodging, and both halfway house and sober living arrangements. Treatment modalities offered include intensive outpatient care, extended residential stays, and standard outpatient services. Employing techniques such as 12-step facilitation, anger management strategies, and cognitive behavioral therapy, the center serves adult men and women, with particular support for survivors of intimate partner violence. The Salvation Army Harbor Light Center also features tailored programs for young adults and emphasizes gender-specific care, ensuring high-quality, personalized recovery journeys for individuals battling addiction.

Salvation Army Harbor Light System

The Salvation Army Harbor Light System in Detroit, MI, is a dedicated facility offering a full spectrum of addiction recovery support. They provide essential detoxification and ongoing substance use disorder treatment through flexible options including intensive outpatient, long-term residential stays, and standard outpatient care. Employing evidence-based methods like 12-step facilitation, anger management, and cognitive behavioral therapy, this center serves adult men and women, with particular sensitivity to individuals affected by intimate partner violence. The Salvation Army Harbor Light System is committed to delivering high-quality, individualized rehabilitation to adults and young adults across all genders seeking to overcome addiction.

Samaria Behavioral Health Center

Situated in Tempe, AZ, Samaria Behavioral Health Center is dedicated to offering targeted treatment programs for both adults and teenagers dealing with substance use issues. This center delivers a variety of outpatient services, such as treatments involving methadone, buprenorphine, or naltrexone, standard outpatient care, brief interventions, cognitive behavioral therapy, and motivational interviewing techniques. Samaria Behavioral Health Center implements specialized programs aimed at adult men, women, and youth, ensuring that care is customized to each individual's needs. The facility welcomes both male and female clients, fostering an environment that is supportive and inclusive throughout the recovery process. Opt for Samaria Behavioral Health Center for extensive addiction treatment that emphasizes high-quality care and tailored strategies.

Samaritan Center Residency Clinic

The Samaritan Center Residency Clinic, situated in Vincennes, IN, provides targeted outpatient services for adults dealing with substance use disorders and co-occurring mental health issues, as well as for children experiencing serious emotional disturbances. This center employs a range of scientifically validated methods, including cognitive behavioral therapy and motivational incentives, to foster healing and recovery. It features distinct programs designed for active military personnel, teenagers, and adult men, accommodating a broad spectrum of client needs. The clinic offers comprehensive outpatient care for both adults and children, including methadone, buprenorphine, or naltrexone treatment. The Samaritan Center Residency Clinic is committed to delivering excellent care within a nurturing setting for those pursuing assistance with addiction and mental health concerns.

SalusCare
Fort Myers, FL

SalusCare in Fort Myers, Florida, delivers complete substance abuse recovery programs for adults and emerging adults. Their offerings include extended stay residential, outpatient, and partial hospitalization options, all grounded in proven therapeutic methods like 12-step support, emotional regulation strategies, and cognitive restructuring. They have dedicated tracks for those facing dual diagnoses of addiction and mental illness, individuals with trauma histories, and survivors of domestic or sexual assault. Furthermore, SalusCare provides supportive housing to aid in the ongoing recovery journey. Committed to excellence, this institution designs personalized treatment plans for men and women aiming for freedom from addiction and mental health struggles.

Samadhi Center Inc
Kingston, NY

Samadhi Center Inc, located in Kingston, NY, provides a range of outpatient services for individuals grappling with substance use disorders. They are particularly adept at addressing complex needs, offering specialized care for adults with co-occurring substance use and serious mental health issues, as well as for children experiencing emotional disturbances. Their treatment modalities include intensive day programs, medication-assisted treatment options like methadone and buprenorphine, and evidence-based approaches such as cognitive behavioral therapy. Samadhi Center Inc distinguishes itself with unique programming tailored for active duty military personnel, adolescents, and adult men. This facility welcomes individuals of all genders across adult, child/adolescent, and young adult populations, with a dedicated emphasis on managing anger and implementing brief, impactful interventions to foster personalized recovery journeys. Samadhi Center Inc is committed to delivering high-quality, individualized rehabilitation to all its clients.

Samaritan Daytop Village Inc

Samaritan Daytop Village Inc, located in Jamaica, NY, delivers an array of addiction treatment options for both adults and youth. The facility specializes in detoxification, treatment for substance use disorders, and care for those facing both addiction and significant mental health challenges. Services include intensive outpatient programs, outpatient care, and detoxification on an outpatient basis. The center employs a range of evidence-based techniques, such as anger management, brief interventions, and cognitive behavioral therapy. Additionally, with programs designed for active-duty military personnel, teenagers, and adult males, Samaritan Daytop Village Inc is committed to providing effective support to all clients, regardless of gender, in their journey toward recovery.

Salvation Army Clitheroe Center

The Salvation Army Clitheroe Center located in Anchorage, AK, specializes in treating adult women who face substance use issues alongside significant emotional or mental health challenges. The center offers a variety of programs including long-term, short-term, and round-the-clock residential options, incorporating methods like 12-step principles, cognitive-behavioral therapy, and strategies for managing anger. It emphasizes recovery from trauma associated with intimate partner violence, domestic abuse, and sexual assault, serving adult, senior, and young adult women. The Salvation Army Clitheroe Center is committed to delivering exceptional care and assistance to help women navigate their recovery process.

Salvation Army Harbor Light Center

The Salvation Army Harbor Light Center, situated in Monroe, MI, delivers a full spectrum of recovery support. They provide detox services, substance abuse counseling, temporary accommodations, and sober living environments. Offering intensive outpatient, extended residential stays, and standard outpatient care, the center serves adults and adolescents of any gender. Tailored services are in place for adult men, adult women, and individuals affected by intimate partner or domestic abuse. The center employs diverse therapeutic methods, including 12-step guidance, anger management techniques, and brief intervention strategies, to personalize each person's journey to recovery.

Samaritan Behavioral Health

Samaritan Behavioral Health in Dayton, OH, delivers a wide array of addiction recovery services tailored for adults and young adults. The center features intensive outpatient programs, standard outpatient care, and detoxification options that do not require hospitalization. Emphasizing methods such as 12-step support, anger management strategies, and short-term intervention techniques, this facility addresses the needs of those grappling with both mental health and substance use challenges. There are specialized programs designed for teenagers and those with intricate treatment requirements. Samaritan Behavioral Health is committed to providing effective support for both men and women on their journey to overcome substance use issues and related mental health disorders.

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Cape Coral, FL

SalusCare, located in Cape Coral, FL, delivers extensive outpatient care for addiction and associated mental health challenges in both young people and adults. This center features distinct services for teenagers, adult women, and individuals facing dual diagnoses. For adults and older adults, regardless of gender, SalusCare embraces a complete recovery strategy. Prioritizing high standards of service, the center guarantees that each person receives individualized support tailored to their specific requirements. If you are looking for effective treatment for substance abuse and mental health within a supportive setting, SalusCare is committed to aiding your path to improved well-being.

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Pittsburgh, PA

The Salvation Army rehabilitation center in Pittsburgh, PA, provides comprehensive care for adults struggling with substance use and co-occurring mental health conditions, as well as children with serious emotional disturbances. Their treatment modalities include 12-step facilitation, anger management, and brief intervention strategies. Services are offered through hospital inpatient, long-term residential, and 24-hour residential settings. The center features specialized programs for adult men, including those affected by intimate partner violence, domestic violence, and sexual abuse. Primarily serving adult men of all ages, from young adults to seniors, the facility ensures high-quality, compassionate support.

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Grand Rapids, MI

The Salvation Army Rehabilitation Center, situated in Grand Rapids, MI, provides a wide range of detox and substance abuse treatment services. This facility offers customized care for both adults and young adults through options such as inpatient detox in a hospital setting, 24-hour inpatient care, and outpatient services. The center specializes in methods like 12-step facilitation, anger management, and brief interventions, serving clients of all genders, including those who have faced domestic or intimate partner violence. Tailored programs for men and women create a nurturing atmosphere for individuals on their recovery journey. Discover personalized care and effective treatment at this esteemed rehabilitation center.

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Clinton Township, MI

Situated in Clinton Township, MI, the Salvation Army Rehabilitation Center provides extensive support for those aiming to recover from substance abuse issues as well as related mental health challenges. This center features tailored programs for adult men and women, including those who have faced trauma, and offers inpatient detox services and treatment within a nurturing atmosphere. Utilizing methods like 12-step programs, anger management, and short-term interventions, the facility serves both adult and young adult clients of all genders. The Salvation Army Rehabilitation Center is committed to offering exceptional care to assist individuals in attaining sustained sobriety and mental health.

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Situated in Anchorage, AK, the Salvation Army Clitheroe Center provides extensive treatment for substance use issues specifically aimed at adult males. This center focuses on addressing co-occurring disorders that involve both substance abuse and significant mental health challenges in both adults and children. It offers various programs, including long-term, short-term, and 24-hour residential options, fostering a nurturing atmosphere conducive to recovery. Employing methods like 12-step approaches, anger management strategies, and cognitive-behavioral therapy, the center customizes its care to meet the specific needs of each individual. Distinct programs are also available for adult men and those who have faced intimate partner violence or sexual trauma. The Salvation Army Clitheroe Center is dedicated to delivering high-quality support for adults, seniors, and young individuals in need of help with substance use issues.

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Vincennes, IN

Situated in Vincennes, Indiana, the Samaritan Center delivers expert outpatient care for individuals, both young and adult, struggling with addiction and associated mental health challenges. The center employs various therapeutic modalities such as anger management, brief intervention strategies, and cognitive behavioral therapy. They offer distinct programs designed for adult men and women, acknowledging the unique requirements of each. The Samaritan Center is committed to providing personalized support to adults and seniors across all gender identities within a nurturing setting. Clients receive superior, scientifically-backed treatment for their recovery path, whether they require outpatient methadone/buprenorphine services or standard outpatient care.

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Samaritan Daytop Village Inc, located in New York, NY, provides extensive residential treatment for adults and children dealing with substance abuse and concurrent mental health issues. The center employs evidence-based strategies, including anger management, cognitive behavioral therapy, and motivational incentives. It specifically serves adult women, those who have experienced intimate partner violence or sexual abuse, and clients requiring trauma-informed care. Catering to adults, seniors, and young adults, Samaritan Daytop Village Inc fosters a secure and nurturing atmosphere for women seeking thorough rehabilitation services aimed at facilitating recovery and personal growth.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)