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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Sandstone Care
Denver, CO

Sandstone Care, situated in Denver, CO, delivers a full spectrum of addiction recovery support for individuals of all ages. Their offerings encompass detox services, comprehensive substance abuse rehabilitation, temporary residences, and sober living environments. Emphasizing personalized treatment plans, Sandstone Care provides intensive outpatient programs, day treatment, and partial hospitalization. They also feature tailored programs for those dealing with trauma, co-occurring mental health and addiction issues, and younger individuals. Employing methods like 12-step integration, emotional regulation training, and short-term therapeutic strategies, the center ensures high-quality care for all. Sandstone Care is committed to supporting individuals on their journey to enduring wellness and restoration.

Sandstone Care
Rockville, MD

Sandstone Care located in Rockville, MD, presents a wide array of addiction recovery services customized to address the specific needs of individuals. The center encompasses detox services, treatment for substance use, transitional housing, and options for sober living. Various program formats are offered, including intensive outpatient, outpatient, and day treatment sessions. Sandstone Care is known for its expertise in 12-step methodologies, anger management, and short intervention strategies. Special programs are designed for teenagers, individuals with a history of trauma, and those experiencing simultaneous mental health and substance use challenges. The facility provides support for adults as well as children and adolescents of every gender, ensuring a focus on delivering high-quality care and comprehensive support for effective recovery.

Sandstone Care
Reston, VA

Situated in Reston, VA, Sandstone Care delivers an extensive array of services aimed at treating addiction for adults, young children, and teenagers. This facility offers various options, including detox, substance abuse treatment, transitional living arrangements, and sober housing. Sandstone Care customizes its treatment strategies to meet personal requirements, featuring programs like intensive outpatient care and outpatient day services. Specialized initiatives are available for adolescents, individuals who have experienced trauma, and those facing both mental health challenges and substance use issues. The center employs techniques such as 12-step programs, anger management, and short interventions, striving to provide exceptional care for all clients, regardless of gender.

Sandstone Care
Darien, IL

Sandstone Care, located in Darien, IL, delivers an extensive array of services aimed at addressing addiction. This center offers detox services, addiction treatment, and transitional living arrangements, including halfway houses and sober living environments. It provides a variety of treatment options such as intensive outpatient programs, outpatient services, and day treatment, serving both adolescents and adults. Sandstone Care employs evidence-informed methodologies including 12-step support, brief interventions, and cognitive behavioral therapy. The facility has a focus on supporting individuals who have faced trauma, along with those dealing with simultaneous mental health and substance use challenges. Programs are customized to cater to the distinct needs of both male and female clientele, ensuring comprehensive and effective care.

Sandstone Care LLC
Crownsville, MD

Sandstone Care LLC, located in Crownsville, MD, specializes in a wide range of rehabilitation services designed for individuals of all ages and genders. The center's expertise includes detox programs, treatment for substance use disorders, and addressing co-existing mental health conditions. It offers various options, such as long-term residential care, detoxification services, and round-the-clock residential support. The facility employs diverse treatment methodologies, including the 12-step approach, anger management techniques, and brief interventions. Additionally, Sandstone Care LLC provides customized programs to meet the needs of adolescents, trauma survivors, and those with concurrent mental health challenges. Committed to delivering high-quality care, the center aims to support recovery for adults, children, and young adults in a nurturing and therapeutic setting.

Sanford West Behavioral Health Campus

Sanford West Behavioral Health Campus, situated in Marne, MI, delivers an extensive array of services for addiction recovery. This center encompasses detoxification, transitional living, intensive outpatient care, long-term residential options, and outpatient programs. Employing methodologies like cognitive behavioral therapy and motivational interviewing, it serves adult men and women, including those affected by intimate partner violence. Focusing on adults and young adults, with customized services for both genders, Sanford West is committed to providing high-quality treatment within a compassionate setting.

Sanstone Care
Crownsville, MD

Sanstone Care, situated in Crownsville, MD, delivers a complete suite of recovery services for those addressing addiction and coinciding mental health conditions. The center excels in extended residential stays, supervised detoxifications, and round-the-clock residential treatment for adults and younger individuals. Emphasizing 12-step principles, emotional regulation techniques, and concise therapeutic approaches, Sanstone Care offers customized assistance to patients managing past traumas, combined illnesses, and significant emotional distress. Through dedicated tracks for teens, those who have experienced trauma, and individuals with multiple diagnoses, this establishment guarantees individualized attention for all genders.

Santa Ana Comprehensive Treatment Ctr

Santa Ana Comprehensive Treatment Ctr located in Santa Ana, CA, provides outpatient detox services, addiction therapy, and treatments involving methadone, buprenorphine, or naltrexone. This center emphasizes a 12-step approach, anger management, and brief intervention techniques, catering to active military members as well as adult men and women. It offers personalized care solutions for both adults and young adults, ensuring attention to individual circumstances. Committed to delivering high-quality support, Santa Ana Comprehensive Treatment Ctr is a reputable option for individuals looking for efficient addiction recovery services in the Santa Ana region.

Santa Barbara Cottage Hospital

Santa Barbara Cottage Hospital, located in Santa Barbara, CA, delivers exceptional substance abuse treatment through its residential offerings. With a commitment to personalized care, the center provides both short-term and round-the-clock residential services for adults and young adults across all genders. Incorporating evidence-backed methods such as cognitive behavioral therapy and 12-step facilitation, the facility also features tailored brief interventions to meet the specific needs of each client. The center's focus on individualized treatment makes it distinct, ensuring every person gets the specialized support they need for effective recovery. If you are looking for addiction treatment that values your personal path to sobriety, Santa Barbara Cottage Hospital might be the right choice for you.

Santa Barbara Cottage Hospital

Santa Barbara Cottage Hospital in Santa Barbara, CA, delivers extensive addiction recovery solutions for adults and emerging adults. This institution delivers focused attention for detoxification, substance misuse intervention, and co-occurring mental health conditions. Emphasizing customized strategies, the hospital provides residential care incorporating 12-step guidance, concise intervention techniques, and cognitive behavioral methods. A distinctive aspect of their approach is the development of treatment programs specifically designed for each individual's unique requirements. Both male and female patients are provided with excellent services in a secure and encouraging atmosphere. For those seeking impactful addiction therapy with a distinct, personalized strategy, Santa Barbara Cottage Hospital stands out as an excellent option.

Sante Center for Healing

Situated in Argyle, Texas, the Sante Center for Healing provides a complete suite of recovery options for adults and young adults battling addiction and coinciding mental health struggles. Their services, which include intensive outpatient, extended residential stays, and outpatient care, utilize methods like 12-step encouragement, emotional regulation training, and concise therapeutic strategies. The Sante Center for Healing also features specific treatment plans designed for active military members, adult males, and adult females. Dedicated to high-quality support, the Sante Center for Healing cultivates a nurturing atmosphere where individuals of any gender can begin their path toward wellness and lasting sobriety.

Santa Maria Hostel Inc

Located in Houston, TX, Santa Maria Hostel Inc specializes in addiction treatment services tailored specifically for adult women. The center offers a range of services, including detoxification, treatment for substance use disorders, transitional living arrangements, and sober housing. Emphasizing 12-step programs, anger management techniques, and cognitive behavioral therapy, it effectively addresses the needs of clients dealing with both substance abuse and mental health challenges, including those who have faced trauma. The facility provides various treatment options such as intensive outpatient, long-term residential, and outpatient programs designed for adults of all ages, ensuring high-quality, gender-focused support for women in their recovery journey.

Santa Fe Recovery Center

Nestled in Santa Fe, NM, Santa Fe Recovery Center delivers an extensive array of addiction treatment services designed for both adults and young adults. The center features detox programs, substance abuse therapies, transitional housing options, and sober living arrangements. Treatment is available in various formats, including intensive outpatient, long-term residential, and standard outpatient services. Santa Fe Recovery Center employs research-backed methodologies such as 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Additionally, tailored programs are available for active duty military members, as well as adult men and women. With an emphasis on personalized care, this center commits to providing high-quality treatment for clients embarking on their recovery journey from addiction.

Santa Fe Mountain Center Inc

Santa Fe Mountain Center Inc, located in Espanola, NM, specializes in outpatient care for individuals dealing with substance abuse and concurrent mental health issues, serving both adults and children. Their treatment offerings encompass techniques such as cognitive behavioral therapy, motivational interviewing, and strategies aimed at preventing relapse. The center is dedicated to providing personalized support for clients who have undergone trauma and those with co-occurring disorders. Catering to adults and young adults of all backgrounds, Santa Fe Mountain Center Inc delivers outpatient treatment options, including methadone/buprenorphine and naltrexone, alongside typical outpatient services. Their holistic approach and customized treatment plans position the center as a crucial support system for individuals pursuing successful recovery.

Santa Catalina
Tucson, AZ

Santa Catalina, located in Tucson, AZ, provides outpatient treatment for substance use, focusing on adults with co-occurring disorders related to substance use and significant mental health challenges, as well as children dealing with serious emotional disturbances. The center employs various methods such as anger management, brief intervention, and cognitive behavioral therapy to deliver high-quality care to adults and seniors of all genders. Additionally, Santa Catalina offers specialized programs for active duty military, adolescents, and adult males, ensuring it meets the needs of a wide array of individuals looking for comprehensive rehabilitation support in a nurturing setting.

Santa Fe Health Services

Santa Fe Health Services, located in Santa Fe, NM, provides outpatient detox and substance abuse treatment designed for both adults and young adults. This center is dedicated to addressing substance use disorders through customized counseling, offering tailored programs for men and women, including those facing concurrent mental health challenges. With an emphasis on outpatient care, Santa Fe Health Services administers methadone/buprenorphine or naltrexone treatments. The facility prioritizes high-quality support, assisting clients on their journey to recovery from addiction. Individuals seeking thorough, specialized treatment in a friendly atmosphere will discover valuable options at Santa Fe Health Services.

Santa Maria Hostel Inc

Santa Maria Hostel Inc in Houston, TX, delivers targeted addiction recovery programs for adult women, older adults, and young adults navigating dual diagnoses of substance use and mental health challenges. The center offers robust intensive outpatient and standard outpatient care, incorporating medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Their therapeutic model emphasizes 12-step principles, anger management strategies, and cognitive behavioral techniques, specifically addressing the needs of individuals with a history of trauma. This facility is distinguished by its personalized programming and dedicated focus on co-occurring conditions, presenting a complete recovery solution. Santa Maria Hostel Inc is recognized for its dedication to high-quality, women-centered care within the realm of substance abuse rehabilitation.

Santa Maria Hostel Inc

Santa Maria Hostel Inc in Houston, TX, provides targeted recovery support for women facing challenges with addiction. Their programs include extended, brief, and round-the-clock live-in treatment options, employing proven therapeutic methods like 12-step integration, emotional regulation skills, and cognitive behavioral strategies. The center is equipped to address co-occurring mental health conditions and serves adult females, with specialized care for those who have encountered trauma. Santa Maria Hostel Inc excels in delivering complete assistance for individuals with multifaceted requirements, fostering a nurturing space for recovery and well-being.

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Saratoga County Addiction Services, situated in Saratoga Springs, NY, is dedicated to providing outpatient care for individuals of all ages struggling with substance use and co-occurring mental health conditions. Their treatment methodology encompasses targeted therapies such as anger management, cognitive behavioral therapy, and brief intervention strategies. The center champions a personalized approach, serving adults and seniors irrespective of gender. Offering medication-assisted treatment options including methadone, buprenorphine, and naltrexone, Saratoga County Addiction Services delivers a holistic recovery experience. Clients can anticipate high-quality, customized programs designed to meet their unique recovery journeys, positioning it as a leading resource for addiction treatment within Saratoga County.

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Sauk County Department of Human Servs, situated in Baraboo, WI, delivers extensive care for adults and youth facing significant emotional challenges and substance use disorders. Their outpatient offerings encompass tailored interventions for those impacted by past sexual abuse. Employing proven methods such as cognitive behavioral therapy and contingency management, the center effectively tackles addiction and mental health issues. Customized treatment plans are available for adult males and females, as well as older adults, ensuring individualized support. Sauk County Department of Human Servs is committed to offering superior recovery services within a nurturing and empowering setting.

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The Sault Tribe Health and Human Services center, situated in Saint Ignace, MI, provides outpatient treatment for substance use disorders, serving both adults and young people. Their approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies. The facility caters to specific needs, including active duty military personnel, adult males, and individuals of any gender, with distinct programs designed for adults and children/adolescents. This dedication to adaptable and high-quality care positions the center as a key provider of individualized addiction recovery services.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)