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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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SaVida Health
Newport, VT

SaVida Health located in Newport, VT, specializes in outpatient treatment for adults and young adults dealing with substance use issues alongside significant mental health challenges or emotional difficulties. The center administers treatments such as methadone, buprenorphine, and naltrexone in conjunction with standard outpatient services. Their methods incorporate techniques like anger management, brief interventions, and cognitive behavioral therapy. SaVida Health serves a diverse population, including men and women who have faced trauma. By offering specialized programs designed for various genders and age categories, this center guarantees customized support and assistance for individuals pursuing in-depth rehabilitation solutions.

SaVida Health
Springfield, VT

SaVida Health, situated in Springfield, VT, delivers thorough outpatient care for individuals struggling with substance use disorders. The center caters to adults and young adults with distinct programs designed for men, women, and those who have undergone trauma. Their approach emphasizes personalized treatment, incorporating techniques such as anger management, brief intervention, and cognitive behavioral therapy. SaVida Health offers outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, in addition to general outpatient services. The facility is committed to providing a nurturing setting and high-quality support for all its male and female clients as they pursue lasting sobriety.

SaVida Health
Saint Johnsbury, VT

SaVida Health in Saint Johnsbury, VT, delivers outpatient services for adults battling substance use disorders, particularly those also facing significant mental health challenges. The facility is equipped to support individuals with emotional difficulties and past trauma. Services encompass outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone), as well as specialized interventions like anger management, brief therapeutic approaches, and cognitive behavioral therapy. SaVida Health provides gender-specific programming for adult men and women. Prioritizing high-quality, personalized care, SaVida Health assists adults and young adults in their journey toward recovery.

SaVida Health
Morrisville, VT

SaVida Health located in Morrisville, VT, provides outpatient services for adults facing substance use challenges and co-occurring mental health disorders, as well as emotional issues in children. The center offers medications such as methadone, buprenorphine, and naltrexone, in conjunction with standard outpatient therapies. Emphasizing approaches like anger management, brief intervention, and cognitive behavioral therapy, the facility supports both men and women, including those who have dealt with trauma. By accommodating adults and young adults of all backgrounds, SaVida Health ensures a high standard of care through customized programs that address the unique needs of each individual, making it an excellent option for those in need of effective rehabilitation support.

SBT Health
Murrieta, CA

At SBT Health in Murrieta, CA, we provide extensive recovery support for individuals struggling with addiction and co-occurring mental health conditions, serving both adolescents and adults. Our diverse treatment options encompass intensive outpatient, outpatient, and day programs. We employ scientifically validated methods including 12-step facilitation, anger management, and brief intervention techniques. SBT Health is dedicated to assisting adults and young adults, regardless of gender, and offers targeted assistance for those managing both chronic pain and substance use challenges. Our commitment to superior care guides individuals toward lasting wellness.

Savida Health
Brattleboro, VT

Savida Health, located in Brattleboro, VT, provides an extensive range of outpatient treatment options for individuals struggling with substance use, catering to both adults and young adults. This center focuses on personalized care through methods such as anger management, brief interventions, and cognitive behavioral therapy. With specific programs designed for adult men, women, and those dealing with trauma, Savida Health prioritizes individualized attention. The facility is inclusive, welcoming clients of all genders in a secure and supportive setting. Patients have the option to engage in outpatient services including methadone/buprenorphine or naltrexone treatments, alongside standard outpatient care. Savida Health is committed to offering exceptional services to help individuals navigate their recovery journey.

Saving My Tomorrow

"Saving My Tomorrow" in Sylmar, CA, provides thorough substance abuse treatment for adults and adolescents. Their offerings include inpatient detox, round-the-clock residential support, and shorter inpatient stays. Emphasizing 12-step programs, anger management techniques, and short-term counseling, this center addresses individuals struggling with both mental health and addiction. They have distinct programs for men, women, and those with more intricate recovery requirements. "Saving My Tomorrow" is committed to delivering personalized, high-quality care to foster enduring sobriety.

SaVida Health
Colchester, VT

SaVida Health, located in Colchester, VT, specializes in outpatient treatment for substance use disorders targeting both adults and young adults, including individuals facing severe mental health challenges. The facility offers treatments involving methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Emphasizing techniques such as anger management, short intervention strategies, and cognitive behavioral therapy, the center serves adult clients, including those who have a history of trauma. SaVida Health is dedicated to providing high-quality care in a nurturing setting for those in need of focused therapeutic support.

SaVida Health
Dover, DE

At SaVida Health, located in Dover, DE, we provide extensive care for substance use disorders via our outpatient services. These include medication-assisted treatment with methadone, buprenorphine, or naltrexone, as well as standard outpatient therapy. Our expertise lies in developing effective relapse prevention plans, and we offer remote therapy options for greater accessibility. SaVida Health has specific programs designed for active military personnel, adult men, and adult women, addressing the varied needs of our clientele. We welcome adults and young adults of all gender identities, offering personalized support and treatment plans to meet each individual's distinct requirements. SaVida Health in Dover, DE is committed to delivering exceptional and results-driven addiction treatment.

Scioto Paint Valley Mental Health Ctr

Situated in Chillicothe, OH, Scioto Paint Valley Mental Health Ctr delivers extensive treatment for adults grappling with significant mental health challenges or emotional issues in youngsters. The facility provides outpatient services, including methadone and buprenorphine therapies, and offers specialized programs such as anger management, cognitive behavioral therapy, and brief intervention sessions. Customized treatment options are available for adult men, women, and survivors of sexual abuse. This center caters to both adults and children/adolescents, ensuring personalized care for all its clients. Scioto Paint Valley Mental Health Ctr is distinguished by its effective treatment offerings and a wide range of services designed to aid individuals in their recovery journey.

SaVida Health
Vergennes, VT

SaVida Health, located in Vergennes, VT, offers outpatient treatment for substance use issues targeting both adults and young adults, with a particular emphasis on co-occurring disorders and severe mental health challenges. The center provides outpatient options including methadone/buprenorphine and naltrexone therapies, employing techniques rooted in evidence-based methods like anger management, brief intervention, and cognitive behavioral therapy. They feature tailored programs designed for adult men and women, as well as individuals with trauma backgrounds. By concentrating on adult and young adult populations, SaVida Health is committed to delivering high-quality care and customized treatment strategies to foster recovery and overall wellness.

SaVida Health
Worcester, MA

SaVida Health, located in Worcester, MA, specializes in outpatient treatment for substance use, prioritizing high-quality care and effective methodologies. The center offers outpatient services for methadone/buprenorphine or naltrexone, along with regular outpatient treatment, and tailored programs for men, women, and individuals who have faced trauma. Their offerings encompass anger management, brief interventions, and cognitive behavioral therapy. SaVida Health serves adults and young adults across all genders, providing a comprehensive and personalized approach to recovery from addiction. If you are looking for research-supported treatment in a nurturing setting, this center is committed to supporting you on your path to achieving long-term sobriety.

Savida Health
Saint Albans, VT

Savida Health in Saint Albans, VT, specializes in outpatient care for adults grappling with substance use disorders and co-occurring severe mental health challenges, as well as for children experiencing serious emotional disturbances. The facility administers medication-assisted treatment options such as methadone, buprenorphine, and naltrexone, alongside standard outpatient services. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Targeted support is available for adult men, adult women, and individuals with a history of trauma. Catering to adults and young adults, Savida Health is dedicated to delivering personalized, high-quality care within a supportive setting aimed at fostering recovery and well-being.

SaVida Health
Newark, DE

SaVida Health, located in Newark, DE, provides outpatient care for adults and adolescents struggling with substance use and co-occurring mental health challenges. Dedicated services are available for military personnel, men, and women. Treatment modalities include outpatient methadone, buprenorphine, or naltrexone. Employing proven strategies such as brief interventions, motivational incentives, and relapse prevention techniques, SaVida Health delivers thorough support. Prioritizing excellence and personalized recovery plans, SaVida Health offers distinct care paths for men and women aiming for sobriety.

SaVida Health
Bennington, VT

SaVida Health in Bennington, VT, is dedicated to providing extensive outpatient care for adults grappling with substance use disorders. Recognizing the profound impact of trauma, the center features tailored programs designed to address these co-occurring challenges. Their therapeutic approach heavily incorporates cognitive behavioral therapy, anger management techniques, and concise, effective interventions, ensuring each individual receives a personalized recovery plan. SaVida Health extends its services to both adults and young adults, offering outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone within a supportive setting. The commitment at SaVida Health is to deliver exceptional care, equipping clients with the tools and encouragement needed to achieve lasting sobriety.

Sault Tribe Health and Human Services

Situated in Sault Sainte Marie, MI, Sault Tribe Health and Human Services delivers an extensive array of services for substance use rehabilitation. The center offers outpatient programs, along with treatments involving methadone, buprenorphine, or naltrexone, in addition to traditional outpatient services. Emphasizing 12-step support, anger management strategies, and short intervention techniques, this facility addresses various client needs. It features specialized programs for active military members, teenagers, and adult males. Catering to both adults and youth of all genders, the center is dedicated to providing personalized care for each client. Discover compassionate care and support at Sault Tribe Health and Human Services.

SaVida Health
Blacksburg, VA

SaVida Health in Blacksburg, VA, delivers accessible outpatient programs designed for adults and adolescents confronting the dual challenges of substance use and significant mental health conditions. Their treatment spectrum encompasses medication-assisted options like methadone, buprenorphine, or naltrexone, alongside comprehensive outpatient services. Therapies offered at the center include strategies for managing anger, brief interventions, and cognitive behavioral techniques. SaVida Health is committed to tailoring treatment plans to each individual, serving both men and women. For those in search of effective and personalized addiction recovery support, SaVida Health presents a compelling option.

SCADD Lebanon Pines

SCADD Lebanon Pines, located in Lebanon, CT, provides extensive long-term residential care for adult males facing challenges with substance use and significant mental health issues. Emphasizing 12-step support, short-term interventions, and cognitive behavioral therapy, this center delivers customized treatment to meet the demands of clients with intricate requirements. Programs specifically designed for adult men, those with dual diagnoses, and individuals entangled with the criminal justice system foster a nurturing atmosphere conducive to recovery. Catering to a range of clients including adults, seniors, and young adults, this facility is dedicated to delivering high-quality care and utilizing evidence-based strategies to assist individuals in achieving sustainable sobriety and mental health stability.

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Situated in Munising, MI, Sault Tribe Health and Human Services provides extensive substance abuse treatment options, including outpatient services and standard outpatient programs. This center is adept at utilizing 12-step facilitation, anger management techniques, and brief intervention strategies. It also features specialized programs designed for active duty military members, adolescents, and adult males. Catering to both adults and younger clients, the facility offers tailored care for male and female individuals alike. Emphasizing high-quality treatment along with diverse specialized programs, this center serves as an important support system for those pursuing impactful and customized addiction recovery solutions.

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Sault Tribe Health and Human Services, situated in Manistique, MI, provides outpatient treatment for substance use that emphasizes 12-step facilitation along with anger management and brief interventions. This center serves a diverse clientele, including active duty military members, adolescents, and adult males, offering tailored services to meet various age-specific needs. It is designed to support both men and women, fostering an inclusive and nurturing atmosphere. With a focus on high-quality care and proven treatment strategies, Sault Tribe Health and Human Services is recognized as a dependable resource for those in need of personalized addiction recovery services.

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Situated in Schoharie, NY, the Schoharie Co Community Services Board delivers extensive treatment for substance use disorders and specialized assistance for those facing dual mental health challenges. This center provides outpatient services, including treatments with methadone, buprenorphine, or naltrexone, along with regular outpatient care designed for adults as well as children and adolescents. Emphasizing 12-step programs, anger management, and brief intervention strategies, the facility supports individuals who have undergone trauma and those with co-occurring conditions. Customized programs for both male and female participants ensure that each person's specific path to recovery is addressed with personalized care and attention.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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